Raf in Biological Technology

Sunesis Reports Financial Results for the Second Quarter 2009

...ogen Idec (Nasdaq: BIIB ) for the selection of a raf kinase inhibitor development candidate for the tre...pate in the co-development and co-promotion of the raf kinase inhibitor resulting from this collaboration...nt with them, and $1.5 million for the Biogen Idec raf kinase inhibitor milestone referred to above. Reve...

Bayer and Onyx Announce Nexavar Data Presentations at 45th American Society of Clinical Oncology Annual Meeting

...olved in both cell proliferation (growth) and angiogenesis (blood supply) - two important processes that enable cancer growth. These kinases included raf kinase, VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-B, KIT, FLT-3 and RET. Nexavar is currently approved in more than 70 countries for the treatment of pa...

AgFeed Industries Enters Into Hog Genetic Program Arrangement with Hypor, the Pig Breeding Division of Hendrix Genetics B.V.

...ding technology innovation, offers AgFeed a robust breeding animal that thrives under all conditions. This is a key requirement in China today." raf Beeren, Director of Hypor Asia, continued "Hypor is committed to providing superior genetics which results in greater profitability for hog producers....

FDA Approves EOVIST(R) to Detect and Characterize Focal Liver Lesions

...volved in both cell proliferation (growth) and angiogenesis (blood supply) - two important processes that enable cancer growth. These kinases included raf kinase, VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-B, KIT, FLT-3 and RET. Nexavar is currently approved in more than 40 countries for the treatment of liver c...

Bayer and Onyx Announce Nexavar Data Presentations at 44th American Society of Clinical Oncology Annual Meeting

...olved in both cell proliferation (growth) and angiogenesis (blood supply) -- two important processes that enable cancer growth. These kinases included raf kinase, VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-B, KIT, FLT-3 and RET. Nexavar is currently approved in more than 40 countries for the treatment of patient...

Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2007 Financial Results

...a Phase 1 dose-escalating clinical trial in patients with advanced solid tumors. In addition, Sunesis is developing novel small molecule inhibitors of raf kinase and other protein kinases in collaboration with Biogen Idec. About Sunesis Pharmaceuticals Sunesis is a clinical-stage biopharmaceutical co...

Sunesis Pharmaceuticals to Present Interim Phase 2 Data for SNS-595 at the 39th Annual Meeting on Women's Cancer

...a Phase 1 dose-escalating clinical trial in patients with advanced solid tumors. In addition, Sunesis is developing novel small molecule inhibitors of raf kinase and receptor tyrosine kinases in collaboration with Biogen Idec. About Sunesis Pharmaceuticals Sunesis is a clinical-stage biopharmaceutica...

Accelerated Community Oncology Research Network, Inc. (ACORN), Initiates a Phase 2b Metastatic Breast Cancer Trial in Cooperation With Bayer and Onyx

...volved in both cell proliferation (growth) and angiogenesis (blood supply) - two important processes that enable cancer growth. These kinases included raf kinase, VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-B, KIT, FLT-3 and RET. Preclinical models have also demonstrated that Raf/MEK/ERK has a role in HCC; therefor...

Sunesis Pharmaceuticals to Present Data at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

...a Phase 1 dose-escalating clinical trial in patients with advanced solid tumors. In addition, Sunesis is developing novel small molecule inhibitors of raf kinase and other oncology kinases in collaboration with Biogen Idec. About Sunesis Pharmaceuticals Sunesis is a clinical-stage biopharmaceutical com...

In Vivo Signal Transduction Pathway Reporting Systems

... of the pathway and screening for drugs that promote or inhibit the activity of JNK, MAPK, PKA or other upstream signaling molecules (such as Ras, raf and JNKK). Conclusions The PathDetect in vivo signal transduction pathway reporting systems can be used to determine and map the signal tran...