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RNA in Biological Technology

Santaris Pharma Director Appointed Adjunct Professor in RNA Biology at the University of Aalborg, Denmark

COPENHAGEN, June 3 /PRNewswire/ -- Santaris Pharma and Copenhagen Institute of Technology, Aalborg University, Denmark, announced today that Director of microRNA, Santaris Pharma, Sakari Kauppinen, has been appointed Adjunct Professor in RNA Biology at Copenhagen Institute of Technology. The a...

MIT reels in RNA surprise with microbial ocean catch

CAMBRIDGE, Mass.--An ingenious new method of obtaining marine microbe samples while preserving the microbes' natural gene expression has yielded an unexpected boon: the presence of many varieties of small RNAs snippets of RNA that act as switches to regulate gene expression in these single-celled...

Santaris Pharma Delivers Six LNA-Based RNA Inhibitors to Enzon Pharmaceuticals Ahead of Schedule

COPENHAGEN, April 27 /PRNewswire/ -- As a testimony to the strength of Santaris Pharma's efficient Drug Discovery Engine, the Company announced today the completion of the delivery of six cancer target drug candidates to their collaboration partner Enzon Pharmaceuticals. All six drug candidate...

LNA-Based RNA oligonucleotides Potently Inhibit Cancer microRNAs

COPENHAGEN, April 20 /PRNewswire/ -- Santaris Pharma announced today promising findings on the in vitro and in vivo activity of microRNA-targeted therapeutics against cancer developed on the basis of its proprietary Locked Nucleic Acid (LNA) Drug Platform. In both in vitro and in vivo models S...

Nobel Laureates to Speak at Keystone Symposia RNA Silencing Conference

SILVERTHORNE, Colo., April 17 /PRNewswire-USNewswire/ -- Keystone Symposia on Molecular and Cellular Biology will convene its conference on "The Biology of RNA Silencing" on April 25, 2009 at the Fairmont Empress Victoria in Victoria, British Columbia. This will be an opportunity to hear two Nobel...

Researchers develop new way to see single RNA molecules inside living cells

Biomedical engineers have developed a new type of probe that allows them to visualize single ribonucleic acid (RNA) molecules within live cells more easily than existing methods. The tool will help scientists learn more about how RNA operates within living cells. Techniques scientists currently...

VIRxSYS Publishes New Study on RNA Therapy

New RNA therapy reversed hemophilia in mice GAITHERSBURG, Md., April 6 /PRNewswire/ -- VIRxSYS Corporation announced today the publication of a new research article, " Trans -splicing into Highly Abundant Albumin Transcripts for Production of Therapeutic Proteins In Vivo," in the journal...

Intradigm Receives Notice of Allowance for Key RNA Interference (RNAi) Patent Covering Potent siRNA Sequence

Issuance Will Give Company Patents in Each of the Three Critical Areas of RNAi Therapeutic Development PALO ALTO, Calif., March 17 /PRNewswire/ -- Intradigm Corporation, a leading developer of targeted, systemic RNA interference (RNAi) therapeutics, today announced that the United States Pate...

Sigma-Aldrich Releases WTA2, a Transplex Whole Transcriptome Amplification Technology for Degraded RNA Samples

WTA2 Kits Offer Rapid, Robust Amplification of Partially Degraded RNA ST. LOUIS, Oct. 28 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) today announced the launch of its TransPlex(R) Whole Transcriptome Amplification (WTA2) technology ( http://www.sigma.com/wta ). TransPlex technology...

Norgen Biotek Corp. Launches Four New Kits for the Purification of RNA and DNA from Plants and Fungi

THOROLD, ON, July 18 /PRNewswire/ - Norgen Biotek Corp., an innovative Canadian biotechnology company focusing primarily on advancing powerful tools for RNA, DNA and protein purifications, today announced the expansion of its product offerings by launching four new kits geared towards the isol...

Intradigm Licenses Key Next Generation RNA Interference (RNAi) Intellectual Property From University of Massachusetts Medical School

Company Continues to Fortify Position in Emerging RNAi Industry through Addition of Important and Novel Small Interfering RNA (siRNA) Structural IP PALO ALTO, Calif., April 9, 2008 /PRNewswire/ -- Intradigm Corporation, a leading developer of targeted, systemic RNA interference (RNAi) therapeu...

Biomatrica's RNAstable(TM) Stabilizes RNA at Room Temperature

SAN DIEGO, Jan. 24 /PRNewswire/ -- Biomatrica, the biostability company that offers innovative technologies for stabilizing biological samples at room temperature, has introduced RNAstable(TM) for preserving RNA at room temperature, eliminating the need for cold storage and shipping. Interes...

Alfacell to Host Webinar on RNA Interference-Like Mechanics of RNase Therapeutics on Nov. 29

Presenters will Include World-Renowned RNase and RNA Researchers SOMERSET, N.J., Oct. 25 /PRNewswire-FirstCall/ -- The RNA interference- like mechanics of ribonuclease (RNase) therapeutics will be the focus of scientific presentations in a Nov. 29 Webinar hosted by Alfacell Corporation (Na...

Sigma-Aldrich and the Universite de Montreal Establish Collaboration for RNA Interference Studies

ST. LOUIS, Oct. 4 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) announced today that it has entered into a collaboration with the Institute of Research in Immunology and Cancer (IRIC) of the Universite de Montreal. This collaboration, made possible through grants from Genome Quebec an...

Team demos safety of RNA therapy

CAMBRIDGE, MA -- Researchers from MIT, Alnylam Pharmaceuticals and other institutions have demonstrated the safety of a promising type of genetic therapy that could lead to treatments for a wide range of diseases such as cancer. The work, which will be published in the Sept. 27 issue of Nature,...

Caliper Life Sciences Introduces High Throughput RNA Assay to Improve Workflow in Gene Expression Studies

- New assay assures integrity of RNA samples; offers improved throughput and walk-away time - HOPKINTON, Mass., Sept. 13 /PRNewswire-FirstCall/ -- Caliper Life Sciences, Inc. (Nasdaq: CALP ) today launched a new high throughput RNA assay for automatically assessing th...

GenVault and the National Center for Forensic Science to Present Novel Technology for Room Temperature Storage of RNA

CARLSBAD, Calif., Oct. 1 /PRNewswire/ -- GenVault Corporation, the leader in room temperature biosample management, together with the National Center for Forensic Science will be presenting data showing stabilization of RNA on GenVault's Reversible Porous Matrix (RPM) storage media at room tem...

Mirus Bio awarded patent on RNA delivery

Madison, Wis. - Mirus Bio Corp. , a Madison-based company engaged in gene therapy and the study of RNA interference, has been granted a United States patent on a new injection delivery method. The company has been working to address the lack of an effective method to deliver nucleic acids suc...

Evaluation of RNA isolated from human tissues: quality control for surgical and postmortem samples

James F. Eliason, Ph.D., Asterand plc Introduction The path to identification of new and improved drugs for the treatment of human diseases often begins with the identification of novel gene targets through RNA expression analysis. Most high thro...

Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents

Abstract Applied Biosystems has developed new techniques that produce highpurity total RNA from biological sources such as cultured cells. These techniques eliminate the need for post-isolation DNase treatment or other manual handling, and produce a highly pure product, free ...

Total RNA Isolation: 100 l Viral Sample From Cultured-Cell Supernatant Containing Virus

AquaPure RNA Isolation Kit Catalog #732-6370 Yield: Dependent on sample and RNA expression levels Method Sample Collection and Handling Samples may be fresh or frozen. Collect fresh virus and isolat...

Total RNA Isolation From 50100 mg Plant Tissue

AquaPure RNA Isolation Kit Catalog #732-6370 Expected yield range: 50200 g RNA Method Cell Lysis 1.Add 50100 mg (0.050.1 g) frozen ground tissue or fresh tissue to a tissue grinder tube on ice a...

Total RNA Isolation From 500 l Body Fluid

AquaPure RNA Isolation Kit Catalog #732-6370 Method Cell Lysis 1. Vigorously add 2.5 ml cell lysis solution to an Oak Ridge centrifuge tube (or other tube rated for high speed) containing 500 l bod...

Quantitation of RNA for Hybridization Blots Using the VersaFluor Fluorometer

Matthew W. Fields, Section of Microbiology, Cornell University, Ithaca, New York 14853 Introduction Biologists frequently monitor the effect of environmental stimuli on living organisms by quantitating mRNA levels. The relative abunda...

Inoculation of Viral RNA and cDNA to Potato and Tobacco Plants Using the Helios Gene Gun

Tuija Kekarainen and Jari P. T. Valkonen, Department of Plant Biology, Swedish University of Agricultural Sciences (SLU), P.O. Box 7080, SE-75007 Uppsala, Sweden Introduction Particle bombardment is a physical method widely used for gene transfe...

RNAPrep - Total RNA Isolation Purification

RNAPrep is a SPRI based magnetic bead purification kit for extracting and purifying total RNA from Eukaryotic cultured cells. RNAPrep is a simple and reproducible 3-step procedure for isolating total RNA for use in applications such as microarray...

RNAClean - RNA & cDNA in vitro Reaction Purification

Agencourts RNAClean kit provides a simple, flexible and highly reproducible method for purifying nucleic acid products generated in common enzymatic RT and IVT reactions such as cDNA and cRNA. The kit is formatted for microarray gene expression analysis...

RNAqueous-96 RNA Isolation Kit Automation Protocol

This protocol was developed for the MultiPROBE II HT Liquid Handling System with a Gripper Integration Platform. Time required: 1 hr 20 min. For more information on the protocol, see the

Unmask Blood RNA for Gene Expression Profiling

GLOBINclear-Human Globin mRNA Removal Kit Depletes alpha and beta globin mRNA from blood total RNA with a simple magnetic bead procedure (no enzymatic treatments) Increases sensitivity of gene ...

Total RNA from Whole Blood for Expression Profiling

RiboPure-Blood with RNAlater Provides Superior Stabilization and Recovery of RNA The RiboPure-Blood Kit recovers twice the RNA yield as the market leader's system RNA later Stabilization Reagen...

SUPERIOR RNA FOR DEMANDING APPLICATIONS

With the emergence of more and more sophisticated techniques for gene expression analysis (e.g. array analysis, real-time RT-PCR), the quality of the RNA used in these studies has become increasingly critical. As The RNA ...

Stabilizing RNA in Fresh and Frozen Tissues for RNA Isolation

RNA later Tissue Collection: RNA Stabilization Solution for Freshly Dissected Tissue and Cells. Problem: Successful RNA isolation requires rapid processing or appropriate storage of the tissue or cell...

Robust High Throughput RNA Isolation from Blood Samples

MagMAX-96 Blood RNA Isolation Kit Mammalian whole blood is a widely used tissue for molecular assays due to abundant genetic information as well as ease and simplicity of sample collection. RNA isolation fr...

RNAlater FAQs: Preserving RNA Before Isolation

Appropriate storage of cells or tissue samples prior to RNA isolation is critical for preservation of intact RNA within those samples. RNA later is an aqueous solution designed specifically to maintain RNA integ...

Preserve Samples for RNA Expression Microarrays RNAlater Around the World

RNA later protects cellular RNA within specimens during sample collection and during shipping. Whether you are in the lab, in the OR, or out in the field, you can use this aqueous, non-toxic Tissue Collection:RN...

Rapidly Prepare Probes and Markers for Small RNA Analysis

mir Vana Probe & Marker Kit Ideal for analyzing miRNA, siRNA, and other small RNAs Prepare high specific activity RNA or DNA probes Includes purification system optimized for recovery of small RNA probes ...

More siRNA Vectors for RNA Interference

Small Interfering RNAs (siRNAs) are short, double-stranded RNA molecules that can target complementary mRNAs for degradation via a cellular process termed RNA interference (RNAi) (Elbashir et al., 2001a). Recent publications have describ...

Protect RNA and Improve Target Cell Identification

LCM Staining Kit Reagents and protocols optimized to minimize endogenous RNase activity Superior identification of target cells provided by histological and fluorescent stains Desig...
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