Older in Biological Technology

Looking Older Than You Are May Have Little to Do With Wrinkles

What's the biggest aging factor and how is it addressed? International Sculptra trainer Dr. Rebecca Fitzgerald, known among her medical colleagues as the "Sculptra guru" here in the U.S., presented her findings on Facial Volume Restoration to an internationally represented group of phys...

GlaxoSmithKline Responds to JAMA Article on the ICES Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes

PHILADELPHIA, Dec. 11 /PRNewswire-FirstCall/ -- The following is GlaxoSmithKline's (NYSE: GSK ) response to the retrospective analysis by the Institute for Clinical Evaluative Sciences (ICES) titled "Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes". GSK believ...

Novavax Reports Second Quarter 2009 Financial Results

...in healthy adults with our trivalent seasonal flu vaccine candidate; Initiate a Phase II clinical study of our trivalent seasonal flu vaccine in older adults; Continue development of our pandemic H1N1 vaccine candidate; Complete definitive license and supply agreements with ROVI; and ...

Biotech Hot in July Driven by Positive Drug Data and Acquisitions

... percent on news that its drug candidate, TC-5214, significantly improved symptoms of major depressive disorder for patients who did not respond to an older drug, Forest Laboratories Inc.'s Celexa. TC-5214 was better than a placebo at improving an overall depression measurement, as well as reducing depress...

Five Questions About Protopic (tacrolimus) Ointment

...et is called Protopic Ointment. Protopic is a prescription ointment used to treat moderate to severe eczema in adults or children two years of age or older who have a normal immune system. Protopic is for use after other prescription medicines have not worked or when a doctor recommends that other prescr...

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

... of bone following traumatic bone injuries, which are affecting a substantial and increasing proportion of the human population as patients survive to older ages along with general improvements in medicine and healthcare. "With the completion of the sale of our InnerCool Therapies operating unit to ...

Lotus Pharmaceuticals, Inc. Announces Patent Pending Gliclazide-Controlled Release Tablets

...w drugs approved by the SFDA and other factors. Additional information regarding risks can be found in the Company's Annual Report on Form 10K and its older filings with the SEC. Accordingly, although the Company believes that the expectations reflected in such forward-looking statements are reasonable, th...

Sunesis Reports Financial Results for the Second Quarter 2009

...at over 13,000 new cases of AML were diagnosed and approximately 9,000 deaths from AML occurred in the U.S. during 2007. AML is generally a disease of older adults, and the median age of a patient diagnosed with AML is about 67 years. A majority of elderly patients are not considered candidates for standar...

FDA Grants First Authorization of a Commercial 2009 H1N1 Flu Test for use During Pandemic Flu Emergency to Quest Diagnostics' Focus Diagnostics Business

...ur data are consistent with CDC data suggesting that this pandemic flu virus is disproportionately affecting children and young adults, as compared to older adults," Jay M. Lieberman, M.D., medical director, Focus Diagnostics, said. "In fact, almost 60 percent of all positive results identified by our test...

Canadian researchers discover gene related to the appearance of aging

...ere investigating the genetic cause of a rare disorder known as cutis laxa type 2 (CL2), which causes skin on the hands, feet and face to be loose and older looking, as well as growth and developmental delays including effects on the brain. In the process, researchers found some interesting correlations wi...

Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease

...pression (3-fold higher), and pneumonia (2-fold higher). According to Professor Roy Jones , Director, The Research Institute for the Care of older People, Bath, United Kingdom, these conditions alone can add significant burden to patients and their loved ones, but in combination with AD, they oft...

2009: Immunotec announces important clinical research initiative: New study to be launched with the goal of improving the quality of the aging process

... decisively to disability in old age and to a loss of quality of life. Resistance training exercise can increase muscle strength, function and mass in older adults. The primary aim of this study is to determine whether taking a cysteine-rich whey protein isolate (IMMUNOCAL(R)) compared to casein (a milk ...

Lixte Biotechnology Holdings' Lead Compound, LB-1.2, Enhances the Effectiveness of Standard Cancer Chemotherapy in Animal Models

... GBM, by itself caused regression but with recurrence of all tumors." Dr. Kovach added "that, since LB-1.2 has a biochemical action similar to an older drug used for anticancer treatment for many years in China, we are cautiously optimistic that LB-1.2 will be well tolerated by cancer patients and hop...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

...en. This could represent an increase of Hib carriage and transmission from older non-symptomatic children to those children whose parents refused vaccinatio...th-care providers to administer the booster dose of Hib vaccine to children older than 12 months of age who were previously deferred, at the next regularly-s...

Preclinical Proof-of-Concept Studies Published for Novavax Seasonal Influenza Virus-Like-Particle Vaccine

...ratory tract, which may be an important factor in preventing influenza-associated pneumonia, a leading cause of flu-related hospitalizations in adults older than 65 years of age. "This study demonstrates the breadth of the immune response induced by the VLP vaccine," said Ted Ross, Ph.D., Assistant ...

Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures

... selective and highly potent type 1 interferon alpha. INFERGEN is indicated for the treatment of chronic HCV infection in patients 18 years of age or older with compensated liver disease who have anti-HCV serum antibodies and /or the presence of HCV RNA. INFERGEN is currently FDA approved for TIW monothe...

New Phase 3 Data Continue to Indicate that Wyeth's Investigational 13-valent Vaccine Has the Potential to Broaden Coverage Against Pneumococcal Disease

...and showed a safety profile comparable to Prevenar. A study of 352 children in Poland assessed the safety and immunogenicity of Prevenar 13 in older children not previously immunized with Prevenar. Children were vaccinated with one of three different catch-up schedules currently recommended for Pr...

Printing New Organs: Foundation Funds Medical Technology That Replicates Human Tissue

...Rejection of transplanted tissue is not a concern; the cells that are used can be taken from youthful progenitor cells from the patient to replace the older diseased cells. Keith Murphy, CEO of Organovo, looks ahead, "Organovo has an exciting technology platform that has attracted broad investment at...

Matrix Genomics, Elizabeth Corder, PhD - Gene Variation in the LRRK2 Gene and High Risk for Parkinson's Disease

... Parkinson's disease is the second most common neurodegenerative disorder in the Western world, and a major cause of disability and distress among older Americans. Family studies have long indicated that Parkinson's is a genetic disorder when certain mutations are inherited. However, specific genetic f...

Optimer Pharmaceuticals Announces Lower Recurrence Rates for Fidaxomicin Versus Vancocin(R) in Subgroup Analyses from Its Phase 3 Study for the Treatment of CDI

...hows that fidaxomicin is more effective than oral vancomycin when it comes to reducing recurrence, even in high risk patient populations such as those older than 65, hospitalized patients, and patients with very low albumin levels," said Mark A. Miller, M.D., Chief of Clinical Microbiology, Head of the Div...

For Medical Device Makers, a New Software Technology Report, Time to Get Rid of Your Old Code from Full Spectrum Software

... Many medical device makers have older products, with old yet still functional software c...re . A must read for any medical device maker with older products. Southborough,... of Your Old Code. Many medical device makers have older products with even...

Vimpat(R) (lacosamide) C-V, a New Antiepileptic Drug (AED), To Be Available in U.S. Pharmacies

...t was approved by the U.S. FDA in the fall of 2008 for the use as an add-on therapy for the treatment of partial-onset seizures in people 17 years and older with epilepsy. (Photo: http://www.newscom.com/cgi-bin/prnh/20090526/NY22555 ) Vimpat approval is based on safety and efficacy data from t...

Schering-Plough Announces Changes to its Global Collaboration with Novartis to Develop Combination Therapies for Asthma and COPD

...fects with ASMANEX in patients 12 years of age and older include headache, allergic rhinitis, sore throat, ...intenance treatment of asthma in those 5 years and older when taken on a long-term, twice-daily basis. FORA...ced bronchospasm (EIB) in those 5 years of age and older when administered on an occasional, as-needed basi...

Sanofi-aventis U.S. to Acquire Oral Chronic Lymphocytic Leukemia Treatment

...ed with fludarabine phosphate. About CLL CLL is a slow-growing cancer of the white blood cells and bone marrow, which arises predominantly in older age groups (the majority of people with CLL are at least 50 years of age). According to the Leukemia & Lymphoma Society, CLL is the most prevalen...

Novavax Reports First Quarter 2009 Financial Results

...accine doses and to provide data to help select doses for future studies in older adults and a Phase III efficacy study. The Company plans to report top-lin...ation of a Phase II clinical study of our trivalent seasonal flu vaccine in older adults. 2009 Financial Results Revenue from operation...

Novavax Announces Enrollment in the Second Phase II Study of its Seasonal Influenza VLP Vaccine Candidate

...d immunogenicity of a broader range of vaccine doses. The purpose of this study is to provide data to help with selecting doses for future studies in older adults and a Phase III efficacy study. Specifically, the trivalent seasonal vaccine containing VLPs against the 2008-2009 H3N2, H1N1, and B influenza...

Disability and Poor Quality of Life Associated With Treatment Failure Gout Patients

...59 years in age. However, due to the poor quality of life associated with the disease, the reported results were more typical of Americans 74 years or older without TFG. Additionally, patient-reported perceptions of their gout-related pain and functioning were even more severe and more consistent than ass...

Under the Microscope: 'Micro IVF'

...ould outweigh diminished pregnancy rate which for young high responders and older poor responders will be minimal. The reason these groups would see a minim...as many embryos to produce the healthy one that will result in a baby. The older poor responders do not make extra embryos with aggressive stimulation and h...

WebReach, Inc. Becomes Mirth Corporation

...lso offer security hardened information appliances and full turnkey hosting. Consequently we're seeing more and more institutions make the switch from older interface engines to Mirth - lowering their total cost of ownership and harnessing the power of data in their legacy systems" said Teichrow. Abo...

Roche Madison Moves to New Facility

...he No. 1 Company to Sell For ( Selling Power). In previous years, Roche has been named as Top Company of the Year by Med Ad News, a Top Company for older Workers (AARP) and one of the Best Companies to Work For in America ( Fortune ). For additional information about the U.S. pharmaceuticals business, v...

Sunesis Pharmaceuticals Reports Fourth Quarter and Full-Year 2008 Financial Results

...at over 13,000 new cases of AML were diagnosed and approximately 9,000 deaths from AML occurred in the U.S. during 2007. AML is generally a disease of older adults, and the median age of a patient diagnosed with AML is about 67 years. A majority of elderly patients are not considered candidates for standar...

Publication of Shire plc's Annual Report 2008

... in one country act in a way that causes concern for prescribers or patients in another country; - if patients, payors or physicians favor older treatments over newer treatments; - if government regulation is stricter for the Group's new products than for existing treatments; ...

Photos: 'Project Runway's' Tim Gunn Launches Addressing Psoriasis(TM) Campaign to Advocate That Patients Shouldn't Let Psoriasis Impact Personal Style

...t to allow the condition to inhibit their personal style. Individuals 18 or older with moderate to severe plaque psoriasis are eligible to enter for a chance...s of the 50 United States and the District of Columbia, 18 years of age and older on date of entry. Contest begins at 12:00:00 (Noon) PM Eastern Time ("ET") ...

FDA Approves SYMBICORT(R) for Chronic Obstructive Pulmonary Disease (COPD)

...FDA approval is based on two pivotal (Phase III) efficacy and safety trials, SHINE and SUN, which evaluated more than 3,600 patients ages 40 years and older with moderate to very severe COPD. (2) These studies demonstrated that patients using SYMBICORT pMDI 160/4.5 mcg had significantly greater mean impro...

Nanotechnologists gain powerful new materials probe

... atoms within the material. Analyzing how neutrons scatter from a sample can tell scientists a great deal about the materials physical properties, but older spectrometers are limited to relatively large samples and offer less range in the conditions under which they can be tested. These limitations are ...

Mindset BioPharmaceuticals (USA) Inc Obtains Notice of Allowance for European Patent Related to Use of Insulin Sensitizers in Senile Dementia, Dementia and Memory Loss

...they need to live but glucose utilization may be impaired in the brain's of older people and especially those suffering from Senile Dementia or other forms o...ementia and also help improve age-related memory loss affecting millions of older people who are not yet demented." Professor Mike Cawthorne, Director ...

European Commission Approves EFIENT(R) (prasugrel) for Patients with Acute Coronary Syndrome Undergoing PCI

...who weighed less than 60 kg (132 lbs), patients who were 75 years of age or older and patients who have had a prior transient ischemic attack (TIA) or stroke. Patients who weighed less than 60 kg, or were 75 years of age or older had increased exposure with prasugrel. The U.S. Food and Drug Adminis...

Genetic information personalizes warfarin prescribing

...proach called machine learning. Researchers tested the performance of 14 models by comparing them to patient outcomes. They found that two modelsan older technique called linear regression and a newer one called support vector regressionwere equally successful when a combination of clinical information ...

Vion Pharmaceuticals Submits New Drug Application for Onrigin(TM)

...ction treatment for patients sixty years of age or older with de novo poor-risk acute myeloid leukemia (A...hase II trial of 85 patients sixty years of age or older with de novo poor-risk AML, supplemented by data...l Phase II trial in patients sixty years of age or older with de novo poor-risk AML. There are four clin...

Proximity Systems' LAN Based Electronic Lock Management System Offers Increased Security, Efficiency and Reporting Capability for Wall-Mounted WorkStations

...e new cost-effective locking system can be ordered with Proximity Systems' retractable wall-mounted computer workstations beginning in April, and many older multi-compartment workstations can also be retrofitted with the new locking system. The locking system combines hardware components and propriet...