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--Highlights prepGEM(TM) Tissue Kit's Rapid, Robust and Reliable DNA Extraction That Generates DNA Templates Outperforming Other Commercial Kits--
-- Samples Prepared from Mouse Tails Using prepGEM(TM) Yielded Over 34 Times the Amount of DNA Produced by Two Commercial Rapid Extraction Kits --...
EVALUATION OF VARIOUS FINANCIAL AND RESTRUCTURING ALTERNATIVES ONGOING VANCOUVER, Nov. 21 /PRNewswire-FirstCall/ - Angiotech Pharmaceuticals, Inc. (NASDAQ: ANPI , TSX: ANP), a global specialty pharmaceutical and medical device company, today announced that the Company had been notified ...
OAKLAND, Calif., May 9 /PRNewswire-FirstCall/ -- (Nasdaq: WHRT, TSX: WHT) Since January 2008, World Heart Corporation (the "Company") has aggressively pursued various financing alternatives to raise additional capital, including through equity financing transactions and corporate collaboration...
Evelyn McGown, Ph.D. , Michael Su, M.S. and Jin Liao, M.D., Ph.D. Molecular Devices Corporation, 8/00 INTRODUCTION Luciferase from the North American firefly (Photinus pyralis) is very popular foruse in Reporter Gene Assays. The enzyme catalyzes the AT...
Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 INTRODUCTION Immunoassays have traditionally employed colorimetric indicators. As such, multiple dilutions of samples were necessary to ensure that they fell within the dynam...
Jinfang Liao, M.D., Ph.D. and Evelyn McGown, Ph.D. Molecular Devices Corporation, 8/00 INTRODUCTION The photoprotein aequorin, a bioluminescent protein from the coelentratejellyfish Aequorea victorea, has proven to be highly sensitive to the trace amou...
INTRODUCTION Pipettors often fail to meet the manufacturers stated specifications 1- 5 and pipetting is a major source of laboratory error even when the pipettor is operating properly. Accuracy and precision specifications typically provided by pipettor manufacturer...
INTRODUCTION Most spectrophotometric methods for inorganic phosphorus (Pi) analysis are based on the color formed upon the reduction of a phosphomolybdate complex. The classic (and still widely-used) method is that of Fiske and Subbarow 1 , in which the reduction is c...
INTRODUCTION Protein concentration is commonly estimated by measuring the absorbance at 280 nm and calculating the concentration using the extinction coefficient of the protein. The procedure is feasible because extinction coefficients are typically obtained using sta...
By Yan Zhang., Molecular Devices Corporation, 1311 Orleans Dr., Sunnyvale, CA 94089. Introduction This application note describes how to use the OliGreen Quantitation Kit from Molecular Probes in the Gemini XS, Gemini EM and SpectraMax M2 mic...
INTRODUCTION β -lactamases are either plasmid or chromosomally encoded bacterial enzymes which hydrolyze β -lactam antibiotics. The majority of β -lactamases produced by clinical isolates are serine active site enzymes. One successful approach to combat...
By Yan Zhang, Molecular Devices Corporation, 1311 Orleans Dr., Sunnyvale, CA 94089. INTRODUCTION This application note describes how to use the NanoOrange Protein Quantitation Kit from Molecular Probes in the Gemini XS, Gemini EM and SpectraMax M2 ...
Evelyn McGown and Michael Su October 1999 Molecular beacons are fluorogenic oligonucleotide probes developed by Kramerand associates to detect specific nucleic acids in homogeneous solutions. 1 4 They are single-stranded oligonucleotides that exist in a hairpin shape becau...
Simon Lydford 1 and Thomas Giller 2 1 Molecular Devices Limited and 2 Axovan Ltd. INTRODUCTION GFP (Green Fluorescent Protein) is an extremely stable protein of 238 amino acids produced by the jellyfish Aequorea victoria 1 that fluoresces in the lower green r...
Anne T. Ferguson, Ph.D. Molecular Devices Corporation INTRODUCTION This application note describes the use of the SPECTRAmax GEMINI XS from Molecular Devices to study the performance of the LIVE/DEAD Viability/Cytoxicity Assay Kit for animal cells....
Evelyn McGown, Ph.D. and Anna Lam, B.S. Molecular Devices Corporation, 8/99 INTRODUCTION Modern assays for proteolytic activity typically use synthetic chromogenic or flu-orogenic peptide substrates. Enzyme selectivity is obtained by choosing a peptide...
...tal Inc., J.P. Morgan Securities Inc., and Lazard Capital Markets LLC are acting as co-managers. The common stock offering and the convertible senior note offering are being conducted as separate public offerings by means of separate prospectus supplements, and neither of these offerings is contingent up...
... equity $59,823 $84,232 ======= ======= note 1: Derived from audited financial statements included in the Company's Annual Report on Form 10-K for the year ended Decemb...
...m domestic and international operations, including the matters described in note 4-Uncertainty in Income Taxes-to the Consolidated Financial Statements in t...ich the Company operates, and (13) the outcome of the matters described in note 13-Contingent Liabilities and Commitments-to the Consolidated Financial Sta...
... functionality and attributes of EHRs and how they are implemented will be critical to the successful implementation and use of these systems." As we note in our formal comments, "Certifying an EHR does not necessarily equate with effectively using the system's available functions nor does implementation...
...uire one common share for $0.044 expiring June 2014. In July 2009, Viral Genetics issued 7,518,796 shares of common stock for conversion of a note of $100,000 issued in July 2008 for the purchase of 49% of the common shares of an early-stage private business engaged in the marketing and design of...
...clinical signs of disease caused by exposure to a dose of aerosolized anthrax spores that was approximately 200 times the median lethal dose. We also note that the safety profile shown in healthy human volunteers provides support for use of raxibacumab in the clinical setting of immediately life-threaten...
Mach One Completes Note Exchange
BELGIUM, Wis., Jan. 22 /PRNewswire-FirstCall/ -- Mach One Corporation (Pink Sheets: MNCN), a biological solutions company that develops products that produce a positive long term benefit to the agricultural and consumer market, announced today that it has completed its Subordinated Note Swap o...EVALUATION OF VARIOUS FINANCIAL AND RESTRUCTURING ALTERNATIVES ONGOING VANCOUVER, Nov. 21 /PRNewswire-FirstCall/ - Angiotech Pharmaceuticals, Inc. (NASDAQ: ANPI , TSX: ANP), a global specialty pharmaceutical and medical device company, today announced that the Company had been notified ...
OAKLAND, Calif., May 9 /PRNewswire-FirstCall/ -- (Nasdaq: WHRT, TSX: WHT) Since January 2008, World Heart Corporation (the "Company") has aggressively pursued various financing alternatives to raise additional capital, including through equity financing transactions and corporate collaboration...
ImaRx Therapeutics Satisfies Abbott Note Obligation Associated With the Acquisition of Urokinase
TUCSON, Ariz., April 23 /PRNewswire-FirstCall/ -- ImaRx Therapeutics, Inc. (Nasdaq: IMRX ) today announced that it has entered into an agreement with Abbott Laboratories pursuant to which it has satisfied its obligations under its $15 million non-recourse promissory note with Abbott issued in...Evelyn McGown, Ph.D. , Michael Su, M.S. and Jin Liao, M.D., Ph.D. Molecular Devices Corporation, 8/00 INTRODUCTION Luciferase from the North American firefly (Photinus pyralis) is very popular foruse in Reporter Gene Assays. The enzyme catalyzes the AT...
Dual-Luciferase Quantitation in the LMax Microplate Luminometer (MaxLine Application Note #39)
Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 INTRODUCTION Reporter gene assays are used to study eukaryotic gene expression. Dual geneticreporters are commonly used in transient transfections of cultured cells tominimiz...Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 INTRODUCTION Immunoassays have traditionally employed colorimetric indicators. As such, multiple dilutions of samples were necessary to ensure that they fell within the dynam...
DNA Quantitation in the LMax Microplate Luminometer (MaxLine Application Note #37)
Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 INTRODUCTION DNA measurements are important for many aspects of molecular biology. Of thespectrophotometric methods available, UV absorbance measurement at 260 nm isthe simpl...ATP Quantitation in the LMax Microplate Luminometer (MaxLine Application Note #40)
Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 INTRODUCTION Adenosine triphosphate (ATP) is present in all living cells. Because the level isstrictly-controlled, assay of ATP can be used as a indicator of viable cell numb...Jinfang Liao, M.D., Ph.D. and Evelyn McGown, Ph.D. Molecular Devices Corporation, 8/00 INTRODUCTION The photoprotein aequorin, a bioluminescent protein from the coelentratejellyfish Aequorea victorea, has proven to be highly sensitive to the trace amou...
INTRODUCTION Pipettors often fail to meet the manufacturers stated specifications 1- 5 and pipetting is a major source of laboratory error even when the pipettor is operating properly. Accuracy and precision specifications typically provided by pipettor manufacturer...
Using the SpectraMax Plus for USP Dissolution Calibration (MaxLine Application Note #27)
INTRODUCTION Calibration of a dissolution apparatus is necessary to produce accurate results for dissolution testing of pharmaceutical dosage forms and to allow comparison between batches and between laboratories. USP requirements for calibration are given in the Appa...UV Absorbance Measurements in SpectraMax Microplate Spectrophotometers MaxLine Application Note #32)
Evelyn McGown, Ph.D. Molecular Devices Corporation. 7/99 In 1994, Molecular Devices introduced SPECTRAmax , the first microplate reader equipped with a monochromator, rather than bandpass filters, for wavelength selection. It was also the first microplate reader capable of m...INTRODUCTION Most spectrophotometric methods for inorganic phosphorus (Pi) analysis are based on the color formed upon the reduction of a phosphomolybdate complex. The classic (and still widely-used) method is that of Fiske and Subbarow 1 , in which the reduction is c...
INTRODUCTION Protein concentration is commonly estimated by measuring the absorbance at 280 nm and calculating the concentration using the extinction coefficient of the protein. The procedure is feasible because extinction coefficients are typically obtained using sta...
By Yan Zhang., Molecular Devices Corporation, 1311 Orleans Dr., Sunnyvale, CA 94089. Introduction This application note describes how to use the OliGreen Quantitation Kit from Molecular Probes in the Gemini XS, Gemini EM and SpectraMax M2 mic...
INTRODUCTION β -lactamases are either plasmid or chromosomally encoded bacterial enzymes which hydrolyze β -lactam antibiotics. The majority of β -lactamases produced by clinical isolates are serine active site enzymes. One successful approach to combat...
By Yan Zhang, Molecular Devices Corporation, 1311 Orleans Dr., Sunnyvale, CA 94089. INTRODUCTION This application note describes how to use the NanoOrange Protein Quantitation Kit from Molecular Probes in the Gemini XS, Gemini EM and SpectraMax M2 ...
Evelyn McGown and Michael Su October 1999 Molecular beacons are fluorogenic oligonucleotide probes developed by Kramerand associates to detect specific nucleic acids in homogeneous solutions. 1 4 They are single-stranded oligonucleotides that exist in a hairpin shape becau...
Simon Lydford 1 and Thomas Giller 2 1 Molecular Devices Limited and 2 Axovan Ltd. INTRODUCTION GFP (Green Fluorescent Protein) is an extremely stable protein of 238 amino acids produced by the jellyfish Aequorea victoria 1 that fluoresces in the lower green r...
Anne T. Ferguson, Ph.D. Molecular Devices Corporation INTRODUCTION This application note describes the use of the SPECTRAmax GEMINI XS from Molecular Devices to study the performance of the LIVE/DEAD Viability/Cytoxicity Assay Kit for animal cells....
Evelyn McGown, Ph.D. and Anna Lam, B.S. Molecular Devices Corporation, 8/99 INTRODUCTION Modern assays for proteolytic activity typically use synthetic chromogenic or flu-orogenic peptide substrates. Enzyme selectivity is obtained by choosing a peptide...
Digital Healthcare Conference starts on a realistic note
Madison, Wis. Information technology managers in healthcare received a heavy dose of reality about IT integration in their field during the opening session of WTN Media's Digital Healthcare Conference . The conference, which is being held May 3 and 4 at the Fluno Center on the University of ...KV Pharmaceutical Announces Stockholder Action to Amend By-Laws is Invalid
...mac e uti c al.com . Cautionary note Regarding Forward-looking Statements The infor...imitation the litigation and claims referred to in note 16 of the Notes to the Consolidated Financial Stat...y by the cautionary statements in this "Cautionary note Regarding Forward-looking Statements" and the risk...Kensey Nash Announces Agreement to Acquire Rights to OsseoFit Product
...e closure, as the inventor and developer of the Angio-Seal(TM) Vascular Closure Device, which is licensed to St. Jude Medical, Inc. Cautionary note for Forward-Looking Statements. This press release contains forward-looking statements that reflect the Company's current expectations about its pros......tal Inc., J.P. Morgan Securities Inc., and Lazard Capital Markets LLC are acting as co-managers. The common stock offering and the convertible senior note offering are being conducted as separate public offerings by means of separate prospectus supplements, and neither of these offerings is contingent up...
SEQUENOM Reports Second Quarter 2009 Financial Results and Highlights
...x(TM), and MassARRAY((R)) are trademarks of SEQUENOM, Inc. All other trademarks and service marks are the property of their respective owners. note to Investors As previously announced, SEQUENOM will hold a conference call to discuss the second quarter and six-month financial results today, Aug...PDI Reports 2009 Second Quarter Financial Results
...alth of strong leadership to the Board and I look forward to working more closely with him in the months and years to come. "Finally, I want to note that while we have begun to benefit from the pharmaceutical industry's strategic shift in outsourced sales, the first half of 2009 was particularly ch...... equity $59,823 $84,232 ======= ======= note 1: Derived from audited financial statements included in the Company's Annual Report on Form 10-K for the year ended Decemb...
Beckman Coulter Completes Acquisition of Olympus' Lab-Based Diagnostics Business
...$780 million, which was funded as follows: Approximately $495 million in net proceeds raised from the issuance of two $250 million senior note offerings of 6- and 10- year maturities with 6% and 7% coupons, respectively. Approximately $240 million in a common stock offering comprised of...Endo Pharmaceuticals Reports Strong Second Quarter 2009 Financial Results
...r current views, expectations and beliefs concerning future events, these forward-looking statements involve risks and uncertainties. Investors should note that many factors could affect our future financial results and could cause our actual results to differ materially from those expressed in forward-lo...Sunesis Reports Financial Results for the Second Quarter 2009
...nd stockholders' equity $9,785,803 $12,783,829 ========== =========== note 1: The condensed consolidated balance sheet as of December 31, 2008 has been derived from the audited financial statements as of that date in......m domestic and international operations, including the matters described in note 4-Uncertainty in Income Taxes-to the Consolidated Financial Statements in t...ich the Company operates, and (13) the outcome of the matters described in note 13-Contingent Liabilities and Commitments-to the Consolidated Financial Sta...
... functionality and attributes of EHRs and how they are implemented will be critical to the successful implementation and use of these systems." As we note in our formal comments, "Certifying an EHR does not necessarily equate with effectively using the system's available functions nor does implementation...
China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2009 Financial Results
...TIVITIES $(17,479,673) $(10,302,291) CASH FLOWS FROM FINANCING ACTIVITIES Proceeds from issue of convertible note $-- $25,000,000 Repayment on loan from shareholders -- -- NET CASH PROVIDED BY/(USED IN) ...New drugs faster from natural compounds: A UC San Diego breakthrough
... a bioinformatics PhD student advised by Pavel Pevzner in computer science and Pieter Dorrestein in the Skaggs School of Pharmacy. The researchers note that currently there is no one place to look for known NRPs, a situation they are trying to change with a new data repository effort. The UC San D......uire one common share for $0.044 expiring June 2014. In July 2009, Viral Genetics issued 7,518,796 shares of common stock for conversion of a note of $100,000 issued in July 2008 for the purchase of 49% of the common shares of an early-stage private business engaged in the marketing and design of...
...clinical signs of disease caused by exposure to a dose of aerosolized anthrax spores that was approximately 200 times the median lethal dose. We also note that the safety profile shown in healthy human volunteers provides support for use of raxibacumab in the clinical setting of immediately life-threaten...
Verenium Completes Amendment to 8% Senior Convertible Notes
...e April 1, 2012 (the "Notes") entered into and announced on July 1, 2009 is effective as of 8:00 a.m. today. The Company has entered into Convertible note Amendment Agreements with holders of 87% of the Notes, which is above the required 66.67% necessary to amend the outstanding Notes. Lazard Freres &am...Other TagsUsingUsingUsingUsingConfirmationSpeakSpeakSpecializedDiabeticDiabeticDiabeticMechanismMechanismMechanismProteomicsDepressionDepressionDepressionMorphineMappingMappingMicroRNAsOther Contentscorneacorneacorneacorneacornealcornealcornealcornealcornscortisolcortisolcortisolcortisolcoughingcoughing
UsingConfirmationSpeakBioinformaticsSpecializedDiabeticMechanismChickadeesProteomicsDepressionMorphineMappingMosaicMicroRNAs
(Date:12/14/2009)... ON, December 10, 2009If you are spending the holidays ... wondering whether you would be better off with another ... , A research team from McMaster University and ... among cichlids, a species that lives in groups, members ... The results appear in the current issue of ...
(Date:12/14/2009)... of the United Nations Framework Convention on Climate ... Agency hosted the ,Bend the Trend, event on ... platform and premiere the screening of the new ... of Europe, a joint project of the European ... and ESA, is a series of short films ...
(Date:12/13/2009)... enzymes that may help to engineer plants that take ... efficiently. The finding could help to engineer crops that ... in the carbon dioxide they need for photosynthesis through ... for each molecule of the gas gained, they lose ... pores can tighten to save water when CO 2 ...
Breaking Biology News(10 mins):'Environmental Atlas of Europe' unveiled at COP15 2Newly identified enzymes help plants sense elevated CO2 and could lead to water-wise crops 2Newly identified enzymes help plants sense elevated CO2 and could lead to water-wise crops 3National Institutes of Health Secures Armory with Patent Pending Technology 10647 1Simple Steps Get Walkers Moving 60853 1New finding suggests prostate biopsy is not always necessary 60850 1New finding suggests prostate biopsy is not always necessary 60850 2New finding suggests prostate biopsy is not always necessary 60850 3(Date:12/15/2009)... Ill. A study in the Dec. 15 issue ... shows that being overweight or obese increases the risk ... not in younger children. , Results indicate ... years of age and older increased 3.5 fold with ... while the risk of OSA did not significantly increase ...
(Date:12/14/2009)... particles carry oxygen, drugs, and more… , ... ... Santa Barbara, in collaboration with scientists at University of Michigan, ... key functions of natural red blood cells, including softness, flexibility, ... , ,The primary function of natural red blood cells is ...
(Date:12/14/2009)... Heska Corporation (Nasdaq: HSKA ; "Heska" ... veterinary diagnostic and specialty products, today announced ... new DRI-CHEM® 7000 Veterinary Chemistry Analyzer (the ... ,, Customers receiving these analyzers have invested ... available to the veterinary in-clinic market. ...
(Date:12/14/2009)... NAPA, Calif., Dec. 14 Tough Enough To ... fight breast cancer, celebrated its fifth anniversary at ... at the Wrangler National Finals Rodeo (Wrangler NFR) ... associated with rough-and-tumble rodeo cowboys, the support of ... as the sold-out crowd sported pink shirts, hats, ...
(Date:12/14/2009)... vary widely and are higher than generally thought, raising concerns about ... University of California, San Francisco (UCSF) imaging specialists. ... ... Radiation doses from common CT procedures vary widely and are higher ... to a new study led by University of California, San ...
Breaking Medicine News(10 mins):Health News:Obesity increases the risk for obstructive sleep apnea in adolescents, but not in younger children 2Health News:Synthetic Red Blood Cells Developed 2Health News:Synthetic Red Blood Cells Developed 3Health News:Heska Announces Installation of New Chemistry Analyzer 2Health News:Heska Announces Installation of New Chemistry Analyzer 3Health News:Tough Enough To Wear Pink(TM) Celebrates Fifth Anniversary 2Health News:Tough Enough To Wear Pink(TM) Celebrates Fifth Anniversary 3Health News:Tough Enough To Wear Pink(TM) Celebrates Fifth Anniversary 4Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 2Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 3Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 4Health News:Variable Doses of Radiation Raise Safety Concerns for CT Procedures 5[1] Obesity increases the risk for obstructive sleep apnea in adolescents, but not in younger children[0] Synthetic Red Blood Cells Developed [0] Heska Announces Installation of New Chemistry Analyzer[0] Tough Enough To Wear Pink(TM) Celebrates Fifth Anniversary[0] Variable Doses of Radiation Raise Safety Concerns for CT Procedures
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