Celsis Outlines the Top Five Advantages of Cryo-plateable Hepatocytes
...A High Throughput Screening Assay for Hepatotoxicity Using Cryopreserved Hepatocytes
Comparison of Fresh and Cryo Cynomolgus Monkey Hepatocyte
cyp P450 Levels
1 Drug Interaction Studies - Study Design, Data Analysis, and Implications for Dosing and Labeling (draft): Guidance...
Celsis In Vitro Technologies and Promega to Offer Fast, Reliable Solutions for ADME-Tox Testing With Primary Hepatocytes
...e with Promega's bioluminescent ADME-Tox assays, including
the P450-Glo(TM)
cyp Assay used to study cytochrome P450 gene induction and
inhibition and the G...ald, vice president and general manager of
Celsis IVT. "Promega's P450-Glo
cyp and GSH-Glo ADME-Tox assays enable
scientists to get results faster. Now w...
Science Fuels DNA Testing Controversy with Prejudicial Misquote
.... (JAMA 286:2270 2001). -- Multiple studies have found that people with
cyp variants require lower doses of the affected medications. Molecular ...ribe without knowing the
patient's age, sex, and medical history, and often
cyp genetics are more
important than all these factors combined.
...
Simultaneous Detection of CYP3A4, CYP2D6 and CYP2C9 Metabolites with a Single, Sensitive, LC/MS/MS Method
...s to discover the underlying mechanisms of drug-drug interactions 3 , drug side effect(s) 4 and toxicity (including hepatotoxicity). Also relevant to
cyp testing is the discovery that polymorphisms in the genetic sequences expressing these enzymes leads to populations of people whose ability to metaboli...