Bacterium in Biological Technology

NewBridge Pharmaceuticals Announces Licensing of Pylera(R) for Middle East, Africa, Turkey & Caspian Region

...e license and supply agreement with Axcan Pharma for Pylera (R) , an innovative 3-in-1 capsule therapy for the eradication of Helicobacter pylori , a bacterium now recognized as being the main cause of gastric and duodenal ulcers. Pursuant to the agreement, NewBridge is entitled to obtain exclusive rights in ...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

...eady stream of available supply, which remains constrained in the short term. About Hib Disease Haemophilus influenzae type b, or Hib, is a bacterium that resides in the upper respiratory tract of humans and is usually transmitted by coughing or sneezing. Invasive Hib disease can be very severe, and...

New Phase 3 Data Continue to Indicate that Wyeth's Investigational 13-valent Vaccine Has the Potential to Broaden Coverage Against Pneumococcal Disease

... submissions expected in 2010. Pneumococcal Disease Pneumococcal disease is complex and describes a group of illnesses, all caused by the bacterium Streptococcus pneumoniae . Pneumococcal disease affects both children and adults, and includes invasive infections such as bacteremia/sepsis and men...

Bacteria from the deep can clean up heavy metals

... solutions, converting it into insoluble manganese oxides. Not only did the bacterium directly oxidize the manganese but the resulting oxides themselves also ab...ly and are known to absorb zinc and nickel; but the oxides produced by this bacterium absorbed two- to three- times more metal. Professor Wang's team showed that...

Scientists determine the structure of highly efficient light-harvesting molecules in green bacteria

...shape, and structure. "Each chlorosome in a green bacterium has a unique organization," said Bryant. "They ar.... They used genetic techniques to create a mutant bacterium with a more regular internal structure, cryo-elect...e chlorosome. First, the team created a mutant bacterium in order to determine why the chlorophyll molecule...

PharmAthene Presents Data for SparVax(TM), a Novel Vaccine for the Prevention and Treatment of Anthrax Infection, at the 12th Annual Conference on Vaccine Research

... About Anthrax According to the Centers for Disease Control and Prevention, anthrax is an acute infectious disease caused by the spore-forming bacterium Bacillus anthracis . Anthrax most commonly occurs in hoofed mammals and can also infect humans. Symptoms of disease vary depending on how the disease...

ImmunoVaccine Technologies Collaborates with Defence Research & Development Canada to Strengthen Canada's Ability to Deal with Biological Threats

...ted, it is well suited for the development of an effective anti-anthrax vaccine." Anthrax is an acute infectious disease caused by the spore-forming bacterium Bacillus anthracis. Infection with anthrax is very serious, and potentially life threatening. Currently, to protect individuals who may come in contac...

Connecting Materials Science With Biology, K-State Engineers Create DNA Sensors That Could Identify Cancer Using Material Only One Atom Thick

...or the most part the two fields are isolated. If you join these two fields, the possibilities are going to be immense. For example, one can think of a bacterium as a machine with molecular scale components and one can exploit the functioning of those components in a material device." For his doctoral rese...

University of Maryland Announces Finalists for $75K Business Plan Competition

...ims to license out patented processes for converting plant fiber to fuel ethanol and other products. University of Maryland researchers discovered a bacterium that can readily digest and ferment various forms of plant fiber to ethanol. Team: Richard Kohn, professor of animal science; Robert Fr...

MIT, BU team combats antibiotic resistance with engineered viruses

...otic-resistant bacteria pose a serious and growing health risk. The Centers for Disease Control and Prevention estimates that the antibiotic-resistant bacterium MRSA, or methicillin-resistant Staphylococcus aureus, causes approximately 94,000 infections and contributes to 19,000 deaths annually in the United S...

PharmAthene Presents Data for SparVax(TM) and Valortim(R), a Novel Vaccine and Anti-Toxin for the Prevention and Treatment of Anthrax Infection at the 7th Annual ASM Biodefense Meeting

... About Anthrax According to the Centers for Disease Control and Prevention, anthrax is an acute infectious disease caused by the spore-forming bacterium Bacillus anthracis . Anthrax most commonly occurs in hoofed mammals and can also infect humans. Symptoms of disease vary depending on how the disease...

Gene against bacterial attack unravelled

...l effect occurs in the body is not yet known. To date, B. Pseudomallei, a bacterium suitable for bioweapons, had managed to elude medics. It can remain hidden ... a 10-figure alarm code. Upon coming into contact with the immune cell each bacterium enters its own Toll code. For known pathogens this sets off an alarm in the...

J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology

...ess in which the team had to build the genome a quarter at a time using the bacterium Escherichia coli to clone and produce the DNA segments. During this build...nts necessary to sustain life, started with M. genitalium because it is a bacterium with the smallest genome known that can be grown in pure culture. This work...

Nephros Provides Corporate Update

...ple reported outbreaks and deaths due to Legionnaire's disease this year in institutional facilities in the U.S. Legionnaire's disease is caused by a bacterium known as legionella pneumophila. Legionella can live in water and is often found in the plumbing systems of buildings such as hospitals, nursing and ...

Medarex and Massachusetts Biologic Laboratories Announce Primary Objective Achieved in Phase 2 Trial of Monoclonal Antibody Combination for the Treatment of Clostridium difficile Associated Diarrhea (CDAD)

...l-designed and well- executed studies is amply demonstrated." About Clostridium difficile Acquired Diarrhea (CDAD) C. difficile is a spore forming bacterium that is common in the environment and can colonize the gastrointestinal (GI) tract. It can be easily spread among hospitalized patients and residents ...

Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R)

...nt). About Anthrax According to the Centers for Disease Control and Prevention, anthrax is an acute infectious disease caused by the spore-forming bacterium Bacillus anthracis. Anthrax most commonly occurs in hoofed mammals and can also infect humans. Symptoms of disease vary depending on how the disease i...

Scientists use light to control proteins

...id protein by inserting a light-sensing protein from an oat plant into an enzyme -- a type of protein that catalyzes biochemical reactions -- from the bacterium E. coli. After engineering the two components together, the researchers found that the enzyme's activity could be manipulated by shining a light on t...

Cepheid Molecular Diagnostic Test for MRSA and S. aureus Categorized 'Moderate Complexity' by FDA

...l laboratory. The key benefit is a potential further reduction in the test time-to-result thereby improving patient management decisions." MRSA is a bacterium that has become resistant to multiple antibiotics including penicillin and cephalosporins. Current culture-based lab testing methods require 24 - 72 h...

Clontech Laboratories, Inc. Recognizes the 2008 Winners of the Nobel Prize in Chemistry

...t green under ultraviolet light. Dr. Chalfie applied GFP to biological research, using it as a visual genetic tag to study biological phenomena in the bacterium Escherichia coli and the model organism Caenorhabditis elegans. Dr. Roger Y. Tsien, a Howard Hughes Medical Institute Investigator of the University o...

Cepheid Receives FDA Clearance for First Rapid On-Demand Molecular Diagnostic Test for MRSA and S. aureus

... expanding test menu, we expect Cepheid's GeneXpert System to continue to be the molecular platform of choice for the management of HAIs." MRSA is a bacterium that has become resistant to multiple antibiotics including penicillin and cephalosporins. Current culture-based lab testing methods require 48-72 hou...

UTSA/UTHSCSA publish results on bio-threat agent

... the Centers for Disease Control. Tularemia is an illness caused primarily by bites or scratches from rabbits, rodents and hares. In most cases, the bacterium causes relatively benign fever, chills and headaches that can be treated with antibiotics. However, when spread by aerosol, the organism can cause sev...

Dartmouth researchers advance cellulosic ethanol production

...neau Distinguished Professor in Environmental Engineering Design at the Thayer School of Engineering at Dartmouth. "In the near term, the thermophilic bacterium we have developed is advantageous, because costly cellulase enzymes typically used for ethanol production can be augmented with the less expensive, ge...

Cyprus and Ireland Add Wyeth's 7-Valent Pneumococcal Conjugate Vaccine (PCV7) to Their National Immunisation Schedules

... Pneumococcal disease affects both children and adults and is a leading cause of illness and death worldwide.(6) Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneum...

Bavarian Nordic A/S - Interim Report for the Period 1 January to 30 June 2008

...ngoing to evaluate several MVA-BN(R) based anthrax vaccine candidates. Originally MVA-BN(R) encoding the Protective Antigen of Bacillus anthracis, the bacterium that causes anthrax, was planned to enter into a Phase I clinical study in late 2008. However, recent evidence suggests that other MVA-BN(R) anthrax v...

UTSA/UTHSCSA publish results on bio-threat agent

... the Centers for Disease Control. Tularemia is an illness caused primarily by bites or scratches from rabbits, rodents and hares. In most cases, the bacterium causes relatively benign fever, chills and headaches that can be treated with antibiotics. However, when spread by aerosol, the organism can cause sev...

UTSA/UTHSCSA publish results on bio-threat agent

... the Centers for Disease Control. Tularemia is an illness caused primarily by bites or scratches from rabbits, rodents and hares. In most cases, the bacterium causes relatively benign fever, chills and headaches that can be treated with antibiotics. However, when spread by aerosol, the organism can cause sev...

Microscopic 'clutch' puts flagellum in neutral

... BLOOMINGTON, Ind. -- A tiny but powerful engine that propels the bacterium Bacillus subtilis through liquids is disengaged from the corkscrew-like flagellum by a protein clutch, Indiana University Bloomington and Harvard Un...

Researchers bring new meaning to the term 'computer bug'

...in the fewest number of flips. In this experiment, the researchers used fragments of DNA as the pancakes. They added genes from a different type of bacterium to enable the E. coli to flip the DNA pancakes. They also included a gene that made the bacteria resistant to an antibiotic, but only when the DNA fra...

Nektar Receives Patent Covering Pulmonary Targeted Antibiotics

...the cells lining their lungs, which leads to secretion of thick, sticky mucus that supports bacteria growth. Pseudomonas aeruginosa is the most common bacterium causing lung infections in people with CF. By the age of 17, nearly 70 percent of people with CF have Pseudomonas aeruginosa in their lungs. Pseudomon...

JCI table of contents: April 22, 2008

... Filling in the blanks: defining a molecular pathway that promotes inflammation and tumor development in the stomach Persistent infection with the bacterium Helicobacter pylori leads to persistent inflammation of the stomach lining and in some individuals stomach cancer, also known as gastric cancer. New i...

MIT's PANTHER sensor quickly detects pathogens

... body. B cells in the body are very fast and very sensitive, Rider said. The CANARY concept uses an array of B cells, each specific to a particular bacterium or virus. The cells are engineered to emit photons of light when they detect their target pathogen. The device then displays a list of any pathogens f...

Solving the Z ring's mysteries may lead to new antibiotics

...orted how a belt-like structure called a Z ring, which pinches a rod-shaped bacterium to produce two offspring, can be disabled by a protein called MinC. By expl...oduce, the infection will die. The researchers focused on the rod-shaped bacterium E. coli, commonly found in the human digestive tract, which serves as a mod...

New approach may render disease-causing staph harmless

...multi-institutional team exploited a chemical pathway that allows the Staph bacterium to defend itself against an immune response. The researchers showed that a ...ction. A golden-colored pigment called a carotenoid gives the S. aureus bacterium its edge. Aureus is Latin for golden. The carotenoid acts as an antioxidant...

Gen-Probe Reports Strong Financial Results for Fourth Quarter and Full Year 2007

...based methods. The collaboration's first MilliPROBE assay targets the bacterium Pseudomonas aeruginosa and is designed as an in-process, early warning system to provide faster, more effective detection of the bacterium in purified water used during drug production. -- Purchase of Blood ...

First documented case of pest resistance to biotech cotton

...so named because they have been genetically altered to produce Bt toxins, which kill some insects. The toxins are produced in nature by the widespread bacterium Bacillus thuringiensis, hence the abbreviation Bt. The bollworm resistance to Bt cotton was discovered when a team of University of Arizona entomol...

Venter Institute Scientists Create First Synthetic Bacterial Genome

...h about 24,000 base pairs (24kb). These 24kb fragments were cloned into the bacterium Escherichia coli to produce sufficient DNA for the next steps, and for DNA ...ponents necessary to sustain life, began with M. genitalium because it is a bacterium with the smallest genome that we know of that can be grown in pure culture....

Life at the jolt

...ste not Bacteria have such a rich diversity that researchers can find a bacterium that can handle almost any waste compound in their daily diet. By linking ...erate electrical power. In the first step of the MFC, an anode respiring bacterium breaks down the organic waste to carbon dioxide and transfers the electrons...

NOLabs AB Achieves Break-Through in Fight Against MRSA-Bacteria

...tone in the development of a new line of products for wounds infected by MRSA-bacteria. MRSA stands for Methicillin Resistant Staphylococcus aureus, a bacterium that is particularly troublesome in hospital-acquired infections due to its resistance to several traditional antibiotics. In experiments performed ...

Massive reanalysis of genome data solves case of the lethal genes

...e was thought to be futile. Now, researchers at DOE JGI have characterized barriers to this gene transfer by identifying genes that kill the recipient bacterium upon transfer, regardless of the type of bacterial donor. These lethal genes also provide better reference points for building phylogenic treesthe me...

FDA Approves DORIBAX(TM) for the Treatment of Complicated Intra-Abdominal and Complicated Urinary Tract Infections

...E. coli, B. fragilis, viridans group streptococci, Proteus species, K. pneumoniae and Pseudomonas aeruginosa. Pseudomonas aeruginosa, a Gram-negative bacterium with increasing multi-drug resistance, is one of the leading causes of hospital-acquired (nosocomial) infections. In general, there are few antibiotic...