DNA2.0 Introduces Freedom of Expression With a New Family of Bacterial Expression Vect:ors

A significant challenge utilizing pET vectors for bacterial expression has been the cost and uncertainty associated with vectors that have been patented. In order to tackle this problem, DNA2.0 has developed a new family of vectors called pJexpress that are free of IP constraints. pJexpress vecto...

Gene against bacterial attack unravelled

Humans have an innate defence system against deadly bacteria. However, how the step from gene to anti-bacterial effect occurs in the body is not yet known. To date, B. Pseudomallei, a bacterium suitable for bioweapons, had managed to elude medics. It can remain hidden in the human body for many ...

Venter Institute Scientists Create First Synthetic Bacterial Genome

Publication Represents Largest Chemically Defined Structure Synthesized in the Lab Team Completes Second Step in Three Step Process to Create Synthetic Organism ROCKVILLE, Md., Jan. 24 /PRNewswire-USNewswire/ -- A team of 17 researchers at the J. Craig Venter Institute (JCVI) has creat...

Verenium Explores Bacterial Genes Inside Termite Guts to Understand How Wood is Broken Down and Converted to Energy

- Study findings published in November 22 issue of Nature - - Company partners with CalTech and DoE for first system-wide gene-analysis of microbial community focused on plant lignocellulose degradation - CAMBRIDGE, Mass., Nov. 21 /PRNewswire-FirstCall/ -- Verenium Corporation (Nasdaq: ...

A simple method to sequence from bacterial colonies using [a-33P] radiolabeled ddNTPs and Thermo Sequenase

Introduction In traditional DNA sequencing systems, sequencing products are radioactively labeled using either endlabeled primers or by the incorporation of radiolabeled dNTPs during primer extension. Successful sequencing results produced by these two labeling methods are hi...

Use of the DCode System to Detect the Food-Borne Bacterial Pathogen Listeria monocytogenes

Nikolaj Schmolker, Fintan van Ommen Kloeke and Gill Geesey, Department of Microbiology and Center for Biofilm Engineering, Montana State University, Bozeman, MT 59717-3980 Abstract Amplification of a region of the 16S rRNA gene of L. monocytoge...

Monitoring Bacterial Genetic Diversity in a Freshwater Lake Using TTGE and DNA Sequence Analysis

Richard Hastings, Jon Saunders and Alan McCarthy School of Biological Sciences, University of Liverpool, Liverpool, UK Introduction Microbial ecology is now firmly focused on the genotypic analysis of naturally-occurring assemblages...

Analysis of Bacterial Assemblage Genetic Diversity in Environmental Samples Using the DCode System

Derek Cody and Laura G. Leff, Department of Biological Sciences, Kent State University, Kent, Ohio Introduction Assessing bacterial genetic diversity in natural environments is problematic because of difficulties in culturing native ba...

RNAlater Preserves Bacterial Gene Expression Profiles for Array Analysis

RNA later Tissue Collection: RNA Stabilization Solution is the worldwide standard for the preservation of RNA in intact animal tissues, organs, and cells. RNA later eliminates the need to immediately process tissue sam...

Perform Microarray Analysis with Limited Bacterial RNA

Linear RNA amplification technology for bacterial gene expression analyses As little as 10 ng of mRNA or 100 ng total RNA required for array analysis Low input requirements enable analys...

Mammalian and Bacterial Expression in One Vector

Novel pdual expression vector for high-level expression in both mammalian and bacterial cells Kerstien A. Padgett Joseph A. Sorge Stratagene Stratagene has developed the pdual expression vector,* which permits high-level expression of heterologous genes in both eukaryotic ...

High-Throughput Cultivation of Bacterial Clones

Culture 192 clones simultaneously with the tempest thermoshaker Jeff Braman Stratagene Figure 1: The tempest Thermoshaker The tempest thermoshaker and a 96-deep-well round-bottom plate were used t...

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Radezolid in Community-Acquired Pneumonia

...cillin-resistant Staphylococcus aureus and other bacterial infections. Radezolid has been shown to be efficac...h most common cause of death in the United States. bacterial CAP is most often caused by pathogens such as S. ...y discovery process and was designed to expand the bacterial spectrum and improve the utility of this class of ...

NovaBay(R) Pharmaceuticals Names Roy J. Wu as Senior Vice President for Business Development

...bioequivalent to the active antimicrobial molecules generated within white blood cells to treat and prevent a wide range of infections without causing bacterial resistance. NovaBay has internal development programs aimed at addressing hospital and respiratory infections. The company has a licensing and researc...

Advanced Life Sciences Receives Complete Response Letter From FDA for Restanza(TM) (Cethromycin) in Community Acquired Pneumonia

...resistant bacteria. Restanza's demonstrated potency and ability to overcome bacterial resistance may be due to its mechanism of action resulting in specificity for its bacterial target. In addition to its utility in CAP, Restanza is also being investiga...

SmartGene's Services for Faster, More Precise Identification of Bacteria and Fungi to be Used by The Johns Hopkins Hospital

...ns Hopkins Hospital will utilize SmartGene's advanced technology and integrated Web-based services to support more rapid and precise identification of bacterial and fungal pathogens by sequence analysis. Some bacteria and fungi do not grow quickly or well enough in culture to support timely, accurate id...

NovaBay(R) Pharmaceuticals to Present at Jesup & Lamont 2009 Growth Stock Conference

...ntibiotics without contributing to the growing rise of antibiotic-resistant bacterial strains. In preclinical testing, the Aganocide compounds have been shown to...blood cells to treat and prevent a wide range of infections without causing bacterial resistance. NovaBay has internal development programs aimed at addressing d...

Genetically engineered bacteria compute the route

...to a number of applications. The second-generation bacterial computers illustrate the feasibility of extending ...red the DNA of Escherichia coli bacteria, creating bacterial computers capable of solving a classic mathematica...published last year in the same journal to produce bacterial computers that could solve the Burnt Pancake Probl...

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

...ack of structural understanding of the mechanism of the vast majority of known nucleic acid sequences. Half of all clinically used antibiotics target bacterial ribosomes, which are RNA-based molecules. Yet, the 3D structures for the complete ribosomes of many pathogenic bacteria are still unknown. Thus, the...

SynCo Bio Partners Increases its Capacities by Expanding its Quality Team

...as been acquired by developing new production processes for a number of international clients and producing a wide variety of different vaccines, live bacterial products and recombinant proteins in our state-of-the-art, GMP-licensed facilities since inception in 2000. Focused solely on biopharmaceutical...

Improving Transfusion Safety: Fenwal, Verax Biomedical Sign Agreement for Rapid, Point-of-Care Bacteria Test

...technology, a rapid diagnostic test used to detect bacterial contaminants in donated blood platelets. ...gents that work together to detect the presence of bacterial contaminants in platelets. The test can be perfor...educing transfusion-related issues associated with bacterial contamination." About Verax Biomedical ...

Novel handheld device detects anthrax with outstanding accuracy and reliability

...nfirm the exceptional accuracy of its Ceeker (pronounced "seeker") portable bacterial detection device in discriminating between anthrax spores and similar-looki... of Canterbury. It uses ultraviolet light and special algorithms to detect bacterial spores and provides test results within minutes, without the need for wet c...

Sorenson Molecular Genealogy Foundation to Protect Archived DNA Using Biomatrica's Room Temperature Storage

...pleMatrix technology and the Biomatrica products utilizing this technology platform (DNAstable(R) for DNA, RNAstable(R) for RNA and CloneStable(R) for bacterial DNA, and PCRboost(R) for stable PCR), visit: www.biomatrica.com . About Sorenson Molecular Genealogy Foundation The Sorenson Molecular Ge...

Celtic Pharma Holdings Announces Investment in Novacta Biosystems Limited

...t year, accounting for twice as many deaths as MRSA. Novacta's pipeline also includes programmes targeting other areas of unmet medical need in bacterial infection. These include novel promising lantibiotic candidates in pre-clinical testing for the treatment of Gram-positive infections including MRSA a...

Enigma Diagnostics Announces Successful Evaluation of the Enigma FL by the UK's Veterinary Laboratories Agency

...as classical swine fever, with minor modifications. The system itself is broadly applicable to many other veterinary pathogens, such as TB in cattle, bacterial infections and other viral infections, such as foot and mouth disease and avian influenza. Allowing vets to use advanced molecular diagnosis in the f...

Rib-X Pharmaceuticals, Inc. Appoints Dr. Russell Greig to Board of Directors

...e ribosome, which performs an essential role in protein synthesis. Many known, commercially valuable antibiotics exert their effects by binding to the bacterial ribosome. The Company's integrated research strategy, which combines state-of-the-art, proprietary computational analysis, X-ray crystallography, medi...

MEDS World, LLC Provides Multiple Environments with Designed Solutions - Wherever People Congregate, MEDS Odor Elimination Solutions Offer Eco-Friendly, Odor-Free Air

...nmental agencies as effective and environmentally friendly odor elimination processes. The release of our EPA registered active-oxidant eliminates the bacterial source of odors. NSF Certified, for use in restaurants, MEDS solutions offer clean air in walk-ins and keep refrigeration units odor free. BLAST, FIBE...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

...sive Hib disease can be very severe, and can cause hospitalization or even death. Before Hib vaccines were available, Hib was the most common cause of bacterial meningitis in the United States. According to the CDC, about 12,000 children each year, most of whom were younger than 5 years of age, got Hib meningi...

Independent U.S. Study Confirms Veritide's Ceeker(TM) Handheld Device Detects Anthrax With Outstanding Accuracy and Reliability

...m the exceptional accuracy of its Ceeker(TM) (pronounced "seeker") portable bacterial detection device in discriminating between anthrax spores and similar-looki... of Canterbury. It uses ultraviolet light and special algorithms to detect bacterial spores and provides test results within minutes, without the need for wet c...

Ganeden Biotech Introduces GanPro(TM) Direct-Fed Microbial for Livestock

...; and 1 gram per day for chickens. The product, which is sold directly by Ganeden Biotech, is available in bulk quantities and 50-pound bags. The bacterial strain in GanPro has been shown to: improve feed conversion ratios by increasing daily weight gain increase immune system re...

Innocoll Announces Provisional Findings From Its Three Phase 2 Clinical Trials Investigating CollaRx(R) GENTAMICIN TOPICAL for the Treatment and Prevention of Diabetic Foot Infections

...tions such as diabetic foot ulcers are often colonized or contaminated with bacterial pathogens that can prevent ulcers from healing. A high proportion of such w...ed with systemic side effects and widespread use can lead to development of bacterial resistance. Furthermore, diabetic ulcers are often associated with vascular...

Phase 3 Cystic Fibrosis Trial Results Presented at European Conference

...fference in microbial growth for specific microorganisms between treatment groups, confirming that Bronchitol does not contribute to the bacterial load in the lung. Bronchitol has received Orphan Drug Designation and fast track status for cystic fibrosis from the U.S. Food and Drug Admini...

Australia: Face Mask That Kills Swine Flu Readied for Australian Pandemic Fight

...plication across consumer products. BioFriend(TM) not only contains and protects against infection, but keeps items of everyday personal use, prone to bacterial and viral contamination, safer and clean. About Filligent Filligent is a Hong Kong biotech company that develops advanced and affordabl...

Techne Corporation Board Member Recognized

...research that holds the promise of new and improved vaccines and innovative ways to harness the power of the immune system to better fight viruses and bacterial illness. Their achievements are nothing short of astounding." Dr. Dinarello, along with Professors Tadamitsu Kishimoto, M.D., Ph.D., and Tosh...

Bacteria from the deep can clean up heavy metals

... more metal. Professor Wang's team showed that the crystal structure of the bacterial manganese oxides is different to that of the chemically produced ones, with... Professor Wang said, "The next stage of our research is to immobilize this bacterial strain into a bioreactor to test its ability to remove manganese and other ...

Optimer Pharmaceuticals Announces Lower Recurrence Rates for Fidaxomicin Versus Vancocin(R) in Subgroup Analyses from Its Phase 3 Study for the Treatment of CDI

...t www.optimerpharma.com . About Fidaxomicin Fidaxomicin is the first in a new class of antibiotics called macrocyclics, which inhibit the bacterial enzyme RNA polymerase, resulting in the death of Clostridium difficile . The narrow spectrum profile of fidaxomicin may eradicate Clostridium diffic...

MIT, BU engineer cellular circuits that count events

...uction of the second protein, a different RNA polymerase. The number of steps in the sequence is, in theory, limited only by the number of distinct bacterial RNA polymerases. "Our goal is to use a library of these genes to create larger and larger cascades," said Lu. The counter's timescale is minutes or...

Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial

...ignant neoplasm, diabetes mellitus, and autoimmune disorders. Equally important to the company are hypertension, hyperlipidemia or atherosclerosis and bacterial infections. For more information, visit www.daiichisankyo.com . Daiichi Sankyo, Inc., headquartered in Parsippany, New Jersey, is the U.S. s...

China Dasheng Biotechnology Company Reports Unaudited Third Quarter FY2009 Financial Results

...r agents market including organic fertilizers, non-chemical agents, and biological agents based additives. The major product line of AM/HM biological bacterial crop and live stock feed additive were certified by the China Green Product Development Center as a "Grade A Green Food Raw Material." To learn more ...

Rib-X Pharmaceuticals Announces Presentations at the 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

...e ribosome, which performs an essential role in protein synthesis. Many known, commercially valuable antibiotics exert their effects by binding to the bacterial ribosome. The Company's integrated research strategy, which combines state-of-the-art, proprietary computational analysis, X-ray crystallography, medi...