Vical Licensee AnGes MG Files NDA in Japan for Collategene Angiogenesis Product
...development went ahead in Japan first. Since last June, when we got the positive results at the interim analysis of our Phase III study in Japan for aso patients with CLI, we have prepared for submission, and are pleased to be the first company in Japan to submit an NDA for a gene therapy product. An...The Gradient Feature: Use in Optimization of Allelic Discrimination Assays, Rev B
...cross-hybridization of target DNA to an aso probe even under the presence of a mismatch. ... mM MgCl 2 , 0.2 M each PCR primer, 0.15 M each aso TaqMan probe, 1.25 U Platinum Taq DNA p... beacon assays is based on the principle of aso hybridization (Wallace et al. 1979). SN...