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Scientists tie several cancers to common 'oncogene engine'

Researchers at Dana-Farber Cancer Institute report that a common "oncogene engine" ?a small family of malfunctioning cell growth switches ?drives several seemingly unrelated, lethal forms of cancer, including malignant melanoma. The finding suggests that it may be possible to attack these different...

U-M researcher and colleagues predict large 2009 Gulf of Mexico 'dead zone'

...ll blanket about 7,980 square miles, roughly the same size as last year's zone, Scavia said. That would put the years 2009, 2008 and 2001 in a virtual tie for second place on the list of the largest Gulf dead zones. It would also mean that the five largest Gulf dead zones on record have occurred since...

March of Dimes awards $250,000 prize to scientists unraveling the causes of muscular dystrophy

...honor of President Franklin Delano Roosevelt, who founded the March of Dimes. The Prize will be awarded to Dr. Campbell and Dr. Kunkel at a gala black tie dinner and ceremony at the InterContinental Harbor Court here. CBS sportscaster Greg Gumbel, member of the March of Dimes national Honorary Board of T...

Bovine genome provides clues to possible new developments

...a faculty member in the CVM. Gill hosted the DNA repository from cattle around the world. Gill is using the SNP resources generated in this study to tie information into the agency's own cattle mapping resource at the AgriLife Research Center in McGregor. Gill also led a team that annotated the genes...

6 young ASU faculty earn NSF Career awards

...the work to young students, and Sodano will establish an "engineering science night" for middle school students and their parents. The binds that tie Arjan van der Vaart's Career award is for $600,000 and will be used to study the binding mechanism of sequence specific DNA-binding proteins. ...

Clarke clarifies pattern recognition theory

...his also means is that we aren't just concerned here with comedic entertainment, but also situations such as when you turn up to work wearing the same tie as a colleague and find yourself laughing. Humour is therefore a faculty for the apprehension of any information, not just a social diversion. "On...

Major step for drug discovery and diagnostics

...iseases such as cancer, cardiovascular diseases and neurological diseases, just to mention at few. The researchers have developed a system, where they tie a tag to the protein that attach it to a surface and make it possible to investigate it in the laboratories. Until now membrane proteins have been ...

Genetic study shows direct link between vitamin D and MS susceptibility 'gene'

...her autoimmune diseases." The research has been welcomed by Simon Gillespie, Chief Executive of the MS Society (UK). "These remarkable results tie together leading theories about the environment, genes and MS but they are only part of the jigsaw," says Mr Gillespie. "This discovery opens up new a...

Weizmann Institute scientists show extra copies of a gene carry extra risk

...enes can cause problems as well. Reiner was the first to discover LIS1's tie to lissencephaly, in 1993. Their latest study shows that it works by helpin...strate the effects of the duplication of a single gene in a mouse model and tie it to a new 'copy number variation' human disease.' ...

Results of the third school nutrition dietary assessment study published

...ergy-dense foods at home, school or other locations and the relationship of the school food environment to their dietary behaviors. Two final articles tie the SNDA-III results to the data on children's body mass index to assess the effects of the school meal programs, the school environment and dietary b...

Full-Featured Video Analytics Platform Available in Smart Camera Format

...he camera) offers a variety of advantages: full frame rate raw video is available to the image processing algorithm; information sparse video need not tie up the network bandwidth -- only video of interest need be transmitted. Additionally, system expansion and management is much simplified -- each camer...

Alternative to burning: environmentally sound disposal for wood chips

... A previous article published in HortScience addressed the nutritional aspects of burning wood chips. Concerns that incorporation of wood chips would tie up nutrients proved not to be the case. According to Lindemann, further research may help refine the practices outlined in the study. He summarized; ...

Duke stem cell biologist wins 3 major awards in 1 month

...em cell environments are constructed, "which will give us new ways to look at biological problems," Kuo said. "This award will provide a basis for and tie together our future work." ...

Natural childbirth linked to stronger baby bonding than C-sections

... The bonds that tie a mother to her newborn may be stronger in women who deliver naturally than in those who deliver by cesarean section, according to a study published b...

Dartmouth researchers discover gene signatures for scleroderma

...rchers also identified a gene signature that highly correlated with increased severity of skin disease. The results, according to Whitfield, help tie together basic and clinical science for scleroderma and could potentially be used as an outcome measure in clinical trials. Studies are in progress, h...

Rats on islands disrupt ecosystems from land to sea, researchers find

...demic researchers tend to do studies and publish them, and then nothing happens. So it's very exciting for our students to see that their research can tie in directly with the conservation mission of a large organization like the Nature Conservancy." ...

WHRC releases 4 key reports

...nt revenues. The carbon market represents a lifeline for poor families that have struggled through more than a decade of war in the DRC. If we can tie reducing greenhouse gasses to moving people out of abject poverty, we will really have achieved something, says Frank Merry, economist and co-author o...

A mechanism to explain biological 'cross-talk' between 24-hour body cycle and metabolism

...roles of heme inside cells is to facilitate the use of oxygen to generate energy in the process known as cellular respiration. The findings further tie together the 24-hour cycle of the body with metabolic function. Circadian rhythms are our sleep-wake cycle and metabolism is how we process food, so i...

Evil genes made me do it

...scinating scientific and personal exploration of the roots of evil, filled with human insight and telling detail. "Evil Genes" is the first book to tie together the cutting edge neuroscientific and genetic results that explain human evil, showing that some deceitful, manipulative, and even sadistic be...

Stevens wins Excellence in Technology Education Award

...the Institutes consistent success in defining the role of the modern technological university. Stevens will be honored by the NJTC at its annual black tie ceremony at the Liberty Science Center in Jersey City, N.J., November 15, 2007. This is a further recognition that Stevens is an institution with bo...

The importance of gene regulation for common human disease

...families, which can help to understand inheritance of genetic variation. The team used these resources to study gene activity in the cell cultures and tie that to DNA sequence variation We have generated an information resource readily available to investigators working in the mapping of variants und...

Modeling the restless brain

...onal model of the human brain would help researchers better understand where the observed resting state fluctuations come from. It also would let them tie neural activity to cognitive and behavioral performance and ask questions about differences in the brains of individual persons. Sporns said thi...

Reconstructing the biology of extinct species: A new approach

...er, because larger animals have absolutely larger canals, the analysis had to take body size into account. The research revealed that this functional tie between the semicircular canals and locomotor pattern is evident both within the primates alone and within the entire mammalian sample. "How an a...

How fish conquered the ocean

...udied various aspects of the physiological adaptations of the fish egg to the marine environment. It is most satisfying that Dr. Finn has been able to tie the threads together in molecular and evolutionary terms with their impressive, comparative sequence alignment study of the involved yolk genes and pr...

Researchers discover mechanism that determines when detailed memories are retained

...t a higher level of acetylcholine during a learning task correlated with more details of the experience being remembered. The results are the first to tie levels of acetylcholine to memory specificity and could have implications in the study and treatment of memory-related disorders. The findings ap...

Slow brain waves play key role in coordinating complex activity

...s that this theta rhythm might be more of an executive control mechanism to tie different brain areas together, whereas high-gamma waves within a region tie groups of cells together and time when their output can be sent or when inp...

Soil nutrition affects carbon sequestration in forests

...below ground, then recycling it back to the atmospheric through respiration. "With sufficient soil nutrition, forests increase their ability to tie up, or sequester carbon in woody biomass under increasing atmospheric CO2 concentrations," says Kurt Johnsen, SRS researcher involved in the project. ...

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

...e and death. Scientists suspect a variety of environmental and genetic factors contribute to fetal hydronephrosis. However, they frequently cannot tie it to any causative factors, making it difficult to determine how normal molecular and cellular processes in kidney development break down in infants ...

In drug design, a loose fit may be best bet

... to and undock from its associated GPCR, activating a succession of G-proteins, and firing signal after signal. A tight connection, alternatively, may tie up a hormone with its GPCR, activating one G-protein, and limiting its signaling ability. In future studies, the scientists hope to determine wheth...

Alaska seal pup diet may hold key to decline of population

...depth. "Our longitudinal study is leading to a better understanding of the role that fat consumption plays in the life of the harbor seal and could tie the declining population of seals and other marine mammals with the change in availability of seal prey, including herring," lead author Lori Polasek ...

Researchers unravel DNA tangles and enzyme seamstresses

...angling often result in cell death. "The exciting part is that these seemingly abstract physical principles we work with can be useful some day to tie up DNA in cancer cells and kill them off," says U of T biochemist Hue Sun Chan, the study's co-author and a Canada Research Chair in proteomics, bioin...

Many needles, many haystacks

...on is crucial, and any change is likely to be disruptive. But so far, because of their size, these motifs have been below the radar of most methods to tie protein structures to disease." ...

Skull study sheds light on dinosaur diversity

...of sauropods were walking with a new wide-gauge stance. We can identify characteristics of titanosaurs that would have allowed that stance, and we can tie the appearance of those features with the proliferation of wide gauge tracks everywhere in the fossil record at the end of the dinosaur era." Wilson w...

Sensor web simulation investigates technique to improve prediction of pollution across the globe

... For asthmatics and for anyone with respiratory problems, air pollution can significantly impair simple everyday activities. NASA is trying to tie together satellites and stations on the ground to develop a "sensor web" to track this pollution and improve air quality forecasts. Understanding ho...

NIH creates nationwide network of molecular libraries screening centers

... to the identification of potential targets for new therapies. Central to this effort are the databases supporting the network, which will allow us to tie together data from diverse fields of science in ways not previously brought to bear on important health problems," said NHGRI Director Francis S. Coll...

Two new retroviruses—transmitted from animals—identified

...n the voice box with a high degree of dexterity that would be tremendously difficult using conventional instruments. They were also able to suture and tie knots deep in the mannequin's throat with relative ease ?a task exceptionally challenging without the aid of robotic technology. In the second stud...

Penn Researchers Use Robotic Surgery

...n the voice box with a high degree of dexterity that would be tremendously difficult using conventional instruments. They were also able to suture and tie knots deep in the mannequin's throat with relative ease ?a task exceptionally challenging without the aid of robotic technology. In the second stud...

Researchers make gains in understanding antibiotic resistance

...different, nearby sites on the ribosome represented by different classes of antibiotics," he said. "The idea is to take a bit of one antibiotic and tie it to another. So, if resistance arises due to a mutation in one site, there is still another binding site that can be targeted. It's like multiple dr...

New Clues Add 40,000 Years to Age of Human Species

...ars old. Forty years ago, radiometric dating methods were less accurate and suggested an age of roughly 130,000 years. No one was able to securely tie both sets of fossils to the same time period. "Fortunately, small pumice fragments from two sediment layers were perfect for precise isotopic dati...
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