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Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

Foreveryone doing or reading a paper about microarray-based experiments,reproductibility, especially inter-lab, is the #1 concern. Can I trustthese results? If I redo the same experiment in one month, will I beable to compare both? The NIH recently demonstrated that microarrays experiments performed in d...

Agilent Technologies releases probe sequence, annotation information for all its commercial gene expression microarrays

Agilent Technologies Inc. (NYSE: A) today announced that it has for the first time released the chip design, probe sequence and annotation information for all of its microarrays. The release of this information is expected to improve cross-laboratory experimental research and cross-platform data comparison. "Full release of the probe sequences is an admirable and responsible position for A...

Characterizing Skin Cancer by Microarrays

Microarray technology can be used to identify each stage of skin cancer tumor (melanoma) progression, according to a newly published report. Christopher Haqq and colleagues dissected a large primary melanoma into r...

Microarrays as phenotype

Microarrays provide a method of quantifying the expression and order of genes in a particular genome -- acting as a surrogate measure of cell physiology, said researchers at Baylor College of Medicine in a report that appears online today in the journal Nature Genetics. "Microarray data are good phenotypes to determine the order of genes and are a good surrogate measure of cell status," sa...

Agilent Technologies introduces advanced zebrafish, mouse microarrays for stem cell and developmental biology research

Which is more likely to happen - you being in a car wreck or being bitten by a shark? Those who answered that cars are greater killers win a free trip to the beach. It's really no contest, says a Texas A&M University professor. Your chances of being in a wreck are far greater than being a shark's lunch, says John McEachran, a professor of wildlife and fishery sciences who has studied...

Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool

A standard Internet protocol that checks errors made during email transmissions has now inspired a revolutionary method to transform DNA microarray analysis, a common technology used to understand gene activation. The new method, which blends experiment and computation, strengthens DNA microarray analysis, according to its Carnegie Mellon University inventor, who is publishing his findings in the...

T-rays: New imaging technology spotlighted by American Chemical Society

T-ray sensing and imaging technology, which can spot cracks in space shuttle foam, see biological agents through a sealed envelope and detect tumors without harmful radiation, was the focus of a recent symposium at the national meeting of the American Chemical Society. Charles A....

Nanowire arrays can detect signals along individual neurons

Opening a whole new interface between nanotechnology and neuroscience, scientists at Harvard University have used slender silicon nanowires to detect, stimulate, and inhibit nerve signals along the axons and dendrites of live mammalian neurons. "We d...

'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage

Researchers have known for years that damaged DNA can lead to human diseases such as cancer, but how damage occurs--and what causes it--has remained less clear. Now, computational chemists at the University of Georgia have discovered for the first time that when a proton is knocked off one of the pairs of bases that make up DNA, a chain of damage begins that causes "lesions" in the DNA. T...

Using dental X-rays to detect osteoporosis

Researchers in the Academic Center for Dentistry Amsterdam have created a unique way of identifying patients at risk of osteoporosis by using ordinary dental x-rays. Professor Paul F. van der Stelt and his team developed the largely automated approach to detecting the disease during a three-year, EU-funded collaboration with the Universities of Manchester, Athens, Leuven, and Malmö. They will pre...