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Study explains potential failure of oral contraceptives with obese women

PORTLAND, Ore. Researchers have identified a potential biological mechanism that could explain why oral contraceptives may be less effective at preventing pregnancy in obese women, as some epidemiological studies have indicated. Although conventional oral contraceptives appear to eventually re...

Forsyth scientists suggest linkages between obesity and oral bacterial infection

A scientific team from The Forsyth Institute has discovered new links between certain oral bacteria and obesity. In a recent study, the researchers demonstrated that the salivary bacterial composition of overweight women differs from non-overweight women. This preliminary work may provide clues to...

Christopher McCulloch receives the IADR Research in Oral Biology Award

Alexandria, Va. The 2009 Research in Oral Biology Award will be presented to Dr. Christopher McCulloch, from the University of Toronto, ON, Canada, at the International Association for Dental Research (IADR) 87th General Session & Exhibition in Miami, Florida, USA, on April 1, 2009. Dr. McCullo...

Childhood chicken pox could affect oral health years later

CHICAGO (February 18, 2009) - You may recall as a child catching the itchy red rash, chicken pox. The unsightly infection was caused by the varicella zoster virus and was responsible for nearly 4 million cases each year, according to the Centers for Disease Control (CDC), until a vaccine introduce...

Advancement in tissue engineering promotes oral wound healing

Tampa, Fla. (Feb. 3rd, 2009) Oral tissue engineering for transplantation to aid wound healing in mouth (oral cavity) reconstruction has taken a significant step forward with a Netherlands-based research team's successful development of a gum tissue (gingival) substitute that can be used for recon...

First trimester smoking linked to oral clefts

Smoking during the first trimester of pregnancy is clearly linked with an increased risk of cleft lip in newborns. Genes that play a role in detoxification of cigarette smoke do not appear to be involved. This is shown in a new study published in the journal Epidemiology . Oral clefts are one...

Human connection to our nation's fisheries comes alive through oral history project

Voices from the Fisheries , an archive of oral histories of recreational and commercial fishermen and the communities and families that rely on them, documents the human experience with the nation's coastal, marine and Great Lakes environments and living marine resources. Social scientists Sus...

Saliva proteins could help detection of oral cancer

PHILADELPHIA Clinicians could detect oral squamous cell carcinoma, a form of oral cancer, using a simple test that detects proteins in saliva, according to a report in the October 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research. This work wa...

Alcohol binges early in pregnancy increase risk of infant oral clefts

A new study by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, shows that pregnant women who binge drink early in their pregnancy increase the likelihood that their babies will be born with oral clefts. The researchers f...

New oral angiogenesis inhibitor offers potential nontoxic therapy for a wide range of cancers

The first oral, broad-spectrum angiogenesis inhibitor, specially formulated through nanotechnology, shows promising anticancer results in mice, report researchers from Children's Hospital Boston. Findings were published online on June 29 by the journal Nature Biotechnology . Because it is nont...

CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients

PHILADELPHIA, May 16, 2008 New data show that CAPHOSOL ( www.caphosol.com ), an advanced electrolyte solution, relieves painful oral mucositis (OM) and improves quality of life for cancer patients undergoing chemotherapy and radiation therapy. These data will be reported in two separate presenta...

Continuous oral contraceptives better at easing pain, bleeding

Continuous oral contraceptives may be more effective than the standard 28-day birth control pills in suppressing the ovary, according to researchers. They say that the continuous pill also causes a significant improvement in pain and behavioral changes. "We have provided a biological proof of ...

Scientists launch first comprehensive database of human oral microbiome

Scientists know more today than ever before about the microbes that inhabit our mouths. They know so much, in fact, that gathering all of the relevant bits of information into one place when designing experiments can be a job in itself. Now, grantees of the National Institute of Dental and Crani...

Scientists launch human oral microbiome database

Boston -- Scientists from The Forsyth Institute and Kings College, London have released a new tool for the research community, the Human Oral Microbiome Database, which provides descriptions of the approximately 600 microbes (bacteria) that are most commonly found in peoples mouths. Most bacteria...

Texas A&M testing oral contraceptives for animals

COLLEGE STATION, Feb. 19, 2008 If youre a land owner and animals such as coyotes or wild pigs are driving you hog wild, help may soon be on the way to control their numbers in a humane way in the form of a birth control pill for animals being developed at Texas A&M Universitys College of Veterin...

Avocados may help prevent oral cancer, OSU study shows

Columbus, Ohio -- Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-cancerous cells from developing into actual cancers, according to researchers at Ohio State University. Researchers found that extracts from Hass avocados kill or stop the gro...

Rapid oral HIV test shows great promise according to MUHC-led research

A convenient, easy to use, and rapid alternative to blood-based HIV testing may become the new standard for field testing according to a new MUHC study. The study shows that the oral fluid-based OraQuick HIV1/2 test is 100 per cent accurate and patients?preferred choice. Senior and lead author ...

First link of oral bacteria and preterm birth found in human

A 37-year-old-mother, who gave birth to a low-weight preemie at 24 weeks, exhibited the first-found link in a human between bacteria found in the mouth and the amniotic fluid of a woman in preterm labor. Using new DNA finger-printing techniques to find bacteria that cannot be cultured and grown ...

Forsyth scientists find three bacteria associated with oral cancer

Scientists at the Forsyth Institute have found that three bacterial species are associated with the most common form of oral cancer--a discovery the researchers hope will lead to a simple diagnostic test for the often-fatal disease. The findings also open the question of whether bacteria might, ...

Biomarkers isolated from saliva successfully predict oral and breast cancer

Screening for breast cancer and the early detection of other tumors one day may be as simple as spitting into a collection tube or cup, according to recent studies by UCLA researchers. In one early study based on a risk model, presented here at the 96th Annual Meeting of the American Association...

Test helps in fight against lung infections and for treating other life-threatening infections

... discharged and is still symptom free after more than one year. In another case, a patient was on a lung transplant waiting list, and was receiving oral and inhaled antibiotics, but showed a continuous decline in health and lung function. The doctors admitted the patient to hospital in an attempt to s...

Microbes and their hosts -- exploring the complexity of symbiosis in DNA and cell biology

...c topics and disciplines related to microbial symbiosis. These include "The oral Microbial Consortium's Interaction with the Periodontal Innate Defense Syst... "another mechanism by which the action of a single bacterial member of the oral consortium can affect the host responses to a wide variety of different bac...

UTMB study identifies women at risk of gaining excessive weight with injectable birth control

...pularity. This study builds upon UTMB research released earlier this year that found DMPA users gain significant weight not seen among women using oral or nonhormonal contraception. The study was supported by the National Institute of Child Health and Human Development. Yen-Chi L. Le, of UTMB's depart...

Skin-like tissue developed from human embryonic stem cells

..., multilayer tissues that mimic human skin and the oral mucosa (the moist tissue that lines the inside of ...th," said Jonathan Garlick, DDS, PhD, professor of oral and maxillofacial pathology at Tufts University Sc...tissues that mimic the lining tissues found in the oral cavity," said Garlick. Using a combination of c...

Healing power of aloe vera proves beneficial for teeth and gums, too

...on as toothpaste, which is to eliminate pathogenic oral microfloradisease-causing bacteriain the mouth. Th...ms have a number of choices when it comes to their oral health, and aloe vera is one of them," says AGD sp...y are interested in a more alternative approach to oral hygiene, they should speak with their dentist to e...

Alzheimer's disease drug treats traumatic brain injury, report GUMC researchers

...rom Georgetown University Medical Center (GUMC). They say this finding suggests that novel therapy might successfully target both conditions. In an oral presentation at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease, the scientists will show that deactivating these pat...

2 reproductive factors are important predictors of death from ovarian cancer

...ious studies indicated that fewer lifetime ovulatory cycles, higher parity, oral contraceptive use, hysterectomy and tubal ligation are associated with decr...e number of lifetime ovulatory cycles a woman has is affected by her use of oral contraceptives, pregnancy and breastfeeding, all of which temporarily cause...

Work in mice will contribute to the study of hereditary diseases that lead to blindness

... work has been recently published in the specialized Journal of Comparative Neurology . Likewise, some of the results obtained have been presented in oral communications and posters in different national and international scientific meetings: VIII European Meeting on Glial Cell Functions in Health and Di...

Funxional successfully completes initial clinical trial of FX125L, an anti-inflammatory drug with a novel mechanism of action

...events or subject withdrawals were observed. The pharmacokinetics of FX125L was linear over the wide dose range studied and consistent with once-daily oral dosing for patients. We are extremely pleased with the outcome of this initial clinical study with FX125L said Konstantinos Efthymiopoulos, CEO o...

Two dietary oils, two sets of benefits for older women with diabetes

...f women like those in our study could use diet, activity and other aspects of a healthy lifestyle to manage their health. But most will probably be on oral medications for the rest of their lives for managing their diabetes and metabolism, which is fine as long as the medications work. We think there's a ...

Clinical trial shows quadriplegics can operate powered wheelchair with tongue drive system

...heir tongues to indicate different commands. A unique set of specific tongue movements was tailored for each individual based on the user's abilities, oral anatomy and personal preferences. For the first computer test, the user issued commands to move the computer mouse left and right. Using these command...

OJ worse for teeth than whitening says Eastman Institute researchers

...pularity of whitening one's teeth, researchers at the Eastman Institute for oral Health, part of the University of Rochester Medical Center, set out to lear...han those who finish a drink quickly. It's also very important to keep good oral hygiene practices, Ren added, by brushing twice daily with fluoride toothpa...

DuoCort: New chronotherapy for adrenal insufficiency

...ciency, a rare disease for which DuoCort has orphan drug designations in Europe and the USA. The new product, a once daily dual-release hydrocortisone oral tablet that comes in both 5 mg and 20 mg sizes, is being developed by DuoCort Pharma AB, a wholly-owned subsidiary. For more information on DuoCort pl...

NYU Langone Medical Center awarded NIH grants totaling $1,560,000

... particular types of microbiomes are more likely to have the early stages of esophageal adenocarcinoma than those who do not. His team will sample the oral cavity, esophagus, and stomach to study the relationship between the microbiome from these body sites and esophageal cancer. Dr. Blaser and Dr. Pe...

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

...Pei, M.D., Ph.D., New York University School of Medicine Mouth and digestive tract: Esophageal Adenocarcinoma $1 million This team will sample the oral cavity, esophagus, and stomach to study the relationship of the microbiome from these body sites and esophageal cancer. Jacques Ravel, Ph.D., Univ...

Chemical in blood may explain susceptibility to bladder pain

...st currently exists for IC, and the cause is unknown. Treatments range from oral medications to exercise for humans, and maintaining a safe environment for ... disorder have the option of bladder distention, dietary changes, exercise, oral drugs, electrical nerve stimulation or surgery. But all treatments target o...

NIH funds $9.5 million for research on HIV and the human innate immune system

...r in the dental school's 117-year history to study oral health as one of the human body's frontline defens...ay healthy. "New evidence surfaces repeatedly that oral health plays an important and integral role in gen...al therapy (HAART) have increased the incidence of oral complications, such as a quadrupled rate of contra...

USC researchers present diabetes findings at American Diabetes Association Scientific Sessions

...ession of diabetes, and how the body becomes aware of low blood sugar. The presentations comprise four symposium lectures, 11 poster presentations, 10 oral presentations and three late-breaking poster presentations. Researchers are available at the meeting to discuss their findings and provide expert c...

Microtest Labs Adds Dissolution Testing to its Suite of Analytical and Stability Testing Services

...ample preparation technique. Samples still need to be analyzed separately, usually by Microtest's HPLC or UV Spectroscopy testing. Typical samples are oral dosage forms, although it can also be used on topicals and transdermal systems. In addition to dissolution testing, Microtest provides a host of ...

Komodo even more deadly than thought: Research

...t the combination of the reptiles' teeth and venom likely accounts for their hunting prowess. "The view that the Komodo routinely kills using dirty oral bacteria is wrong," says research co-author, Dr Stephen Wroe from the University of New South Wales, Australia. "The dragon is truly poisonous. It has...
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