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mimics in Biological News

Synthetic catalyst mimics nature's 'hydrogen economy'

CHAMPAIGN, Ill. By creating a model of the active site found in a naturally occurring enzyme, chemists at the University of Illinois have described a catalyst that acts like nature's most pervasive hydrogen processor. The researchers describe their work in a paper accepted for publication in th...

Scientists create tough ceramic that mimics mother of pearl

Biomimicry technological innovation inspired by nature is one of the hottest ideas in science but has yet to yield many practical advances. Time for a change. Scientists with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have mimicked the structure of mothe...

Mouse model developed at UT Southwestern mimics hyperglycemia, aids in diabetes research

DALLAS June 2, 2008 UT Southwestern Medical Center researchers have genetically engineered a laboratory mouse in which pancreatic beta cells can regenerate after being induced to die. The new animal model's regenerative ability may provide future insights into improved treatments of diabetes, wh...

Genetic variant mimics effect of heart failure medications

A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected. Thats the conclusion of a research team led by investigators at the University of Maryland School of Medicine in Baltimore and the Washing...

Team of chemists receives $5 million grant to develop enzyme mimics

EVANSTON, Ill. --- Mother Nature regulates critical cellular activities in plants and animals by using enzymes, catalysts that bring about specific biochemical reactions. Looking to learn from nature, a team of Northwestern University chemists has received a $5 million grant from the Air Force Off...

How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of 'fullness'

Yaniv Linde in his lab. Millions of people the world over suffer today from obesity, yet there is no “magic bullet” that has yet provided a universally accepted solution. However, a young researcher at the Hebrew University of Jerusalem feels he has come up with a practical weight loss solution...

Researchers create artificial enzyme that mimics the body's internal engine

The protein cytochrome c oxidase (CcO) is the ultimate enzyme responsible for all aerobic life on Earth, from bacteria to people. It is also a crucial component of the cellular machinery that generates energy in our body. With such impressive credentials, you might expect that scientists would have...

MIT's ocean model precisely mimics microbes' life cycles

Scientists at MIT have created an ocean model so realistic that the virtual forests of diverse microscopic plants they "sowed" have grown in population patterns that precisely mimic their real-world counterparts. This model of the ocean is the first to reflect the vast diversity of the invisible ...

Mouse mimics chronic leukemia, will aid drug development

A study by cancer researchers here reveals that a new strain of mice offers the first real animal model for an incurable form of chronic leukemia and should greatly aid the development of new drugs for the disease. The mouse, called the TCL-1 transgenic mouse, develops a malignancy that closely...

Poison dart frog mimics gain when birds learn to stay away

Studying neotropical poison dart frogs, biologists at the University of Texas at Austin uncovered a new way that the frog species can evolve to look similar, and it hinges on the way predators learn to avoid the toxic, brightly colored amphibians. In the Mar. 8 issue of Nature, Catherine Darst a...

Engineered mouse mimics cognitive aspects of schizophrenia

Researchers have developed a mouse strain in which the abnormal activity of the dopamine machinery in a specific part of the brain causes cognitive and behavioral impairments mimicking those in human schizophrenics. The achievement is important, because creating an animal model of any schizophren...

Largest computational biology simulation mimics life’s most essential nanomachine

With preliminary results from a study in Botswana, Harvard School of Public Health researchers have found that people with HIV-1 subtype C in resource-poor settings, who receive antiretroviral (ARV) therapy, can achieve comparable results to those in the developed world. A fully supported health ca...

Bacterial protein mimics host to cripple defenses

Like a wolf in sheep's clothing, a protein from a disease-causing bacterium slips into plant cells and imitates a key host protein in order to cripple the plant's defenses. This discovery, reported in this week's Science Express by researchers at the Boyce Thompson Institute (BTI) for Plant Researc...

Bladder cells feel stretch

...4' protein abundantly expressed in urothelial cells. The group developed a special apparatus to measure cell responses upon stretch stimulation, which mimics bladder distension. Upon stretch stimulation, robust Ca2+ influx and following ATP release were observed in urothelial cells. These phenomena were a...

Symposium to discuss geoengineering to fight climate change at the ESA Annual Meeting

...he climate by releasing light-colored sulfur particles or other aerosols into the atmosphere to reflect the sun's rays back into space. This approach mimics what happens naturally when volcanoes erupt; in 1991, for instance, an eruption of Mount Pinatubo in the Philippines cooled the Earth by 0.9 degrees F...

Scientists closer to making implantable bone material, thanks to new research

... have had bone removed because of tumours or accidents live in real pain. By repairing bone defect sites in the body with bone-like material that best mimics the properties of their real bone we could improve their lives immeasurably. Our study provides an important insight into how different cell sources c...

Plastics chemical retards growth, function of adult reproductive cells

...o that of estradiol, a key steroid hormone, and it can bind to estrogen receptors on the surface of some cells. It is not known whether BPA blocks, or mimics or enhances estrogen's activity on these cells, Flaws said. Human studies have found BPA in many tissues and fluids, including urine, blood, breast...

DuoCort: New chronotherapy for adrenal insufficiency

...ew drug has been developed to produce a physiological release profile that mimics the bodys natural secretion pattern of cortisol to improve outcomes for pat...ogical diurnal serum cortisol profile after single-dose administration that mimics the natural secretion pattern of cortisol. The new DuoCort therapy showed n...

Scripps Research scientists observe human neurodegenerative disorder in fruit flies

...e, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States...

Crustacean shell with polyester creates mixed-fiber material for nerve repair

...rmance for strength, flexibility and resistance to compression under both dry and wet conditions. Under wet conditions, which the researchers say best mimics those in the body, the chitosan-polyester blend required twice as much force to push the tube halfway shut as the other biomaterial, and eight times a...

Simple drug treatment may prevent nicotine-induced SIDS: Study

...speculated that chemicals released from nerves might interact with adrenal cells and cause them to lose oxygen sensitivity. It turns out that nicotine mimics the effects of one of these chemicals, thereby allowing us to test the idea. The present study was significant in that it led to a mechanistic unders...

One size does not fit all

...integrity of myelin in the brain and on the remyelination process. The study uses a model of myelin damage that has relatively little inflammation and mimics the demyelinating aspect of MS, allowing MNI researchers to determine the direct effect of long-term statin therapy on remyelination, independent of i...

MIT: New tissue scaffold regrows cartilage and bone

...started clinical trials in Europe. The scaffold has two layers, one that mimics bone and one that mimics cartilage. When implanted into a joint, the scaffold can stimulate mesenchy...

Small molecules might block mutant protein production in Huntington's disease

...ed their formation. In some cells, some of the RNA mimics drastically cut the production of both mutant and ...er tweaking of the molecular structures of the RNA mimics will be needed to minimize the effects on normal p...ure studies, the researchers plan to try these RNA mimics in whole animals, using several different mutation...

Some vocal-mimicking animals, particularly parrots, can move to a musical beat

..., the YouTube video database. Schachner systematically searched the database for videos of animals moving with the beat of the music, including vocal mimics such as parrots and vocal non-mimics such as dogs and cats. Schachner analyzed the videos frame-by-frame, using the same analyses applied to the ...

Towards a natural pacemaker

...inson's work helps to shed light on the secrets of the HCN channels, but more importantly describes a cell culture they have developed that accurately mimics HCN function in whole mammalian hearts, making future research in the area far quicker and easier. The researchers used their new cellular model to...

Researchers develop flow sensors based on hair structures of blind cavefish

... In a presentation on March 20 at the American Physical Society meeting, researchers from Georgia Tech described their engineered motion detector that mimics the underwater flow measurements made by the blind cavefish. This research was sponsored by the Defense Advanced Research Projects Agency (DARPA). ...

Scripps research scientists 'watch' as individual alpha-synuclein proteins change shape

... resolve shape complexity in the system. To coax the protein to change shapes, the researchers increased the concentration of a soapy solution that mimics the lipids found in different nerve cell membranes in the brain. Alpha-synuclein is known to bind to membranes on nerve cells, and lipids are a large ...

Addiction: Insights from Parkinson's disease

... the ability to experience pleasure, reward and pain. Parkinson's patients lack dopamine and are often treated with dopamine agonists, medication that mimics dopamine action. "In some instances Parkinson's disease (PD) patients become addicted to their own medication, or develop behavioural addictions s...

Food counterfeiting, contamination outpace international regulatory systems

...n lies the counterfeiter, seeking not to harm but to hide the act for profit. The melamine incidents are such examples. As an industrial chemical that mimics protein content in tests was added to milk and subsequently created kidney problems for children. Product counterfeiting is the focus of a presenta...

Single gene lets bacteria jump from host to host

...d and the reef-dwelling pinecone fish. In the squid, which feeds at night near the ocean surface, one strain of the bacterium forms a light organ that mimics moonlight and acts like a cloaking device to shield the squid from hungry predators below. In the pinecone fish, another strain of the bacterium colon...

Natural brain substance blocks weight gain in mice, UT Southwestern researchers discover

...ice show no sleep/wake disturbance or other serious side effects," Dr. Yanagisawa said. "This study suggests that if we can develop a compound that mimics the action of orexin on its receptor, we might be able to treat narcolepsy and other sleep disorders, as well as obesity," Dr. Yanagisawa said. "We ha...

Biomedical researchers create artificial human bone marrow in a test tube

...l drug testing, closer study of immune system defects and a continuous supply of blood for transfusions. The substance grows on a 3-D scaffold that mimics the tissues supporting bone marrow in the body, said Nicholas Kotov, a professor in the U-M departments of Chemical Engineering; Materials Science and...

UC Davis researchers exploring gene therapy to fight AIDS

...Institute for Regenerative Cures in Sacramento. "We are working on a similar approach to genetically engineer a patient's own stem cells in a way that mimics this natural immunity. The German case offers further proof that genetic engineering provides a pathway to success, and gene therapy offers real hope ...

Scripps research scientists identify blood component that turns bacteria virulent

...sis, and whether this belief was correct," Perego said. "Now, we know that it is bicarbonate and that the growth in the presence of bicarbonate really mimics the host growth conditions." In their current study, the Perego lab identified a previously unknown ATP-binding cassette transporter (ABC-transport...

Sniffing out a better chemical sensor

... Marrying a sensitive detector technology capable of distinguishing hundreds of different chemical compounds with a pattern-recognition module that mimics the way animals recognize odors, researchers at the National Institute of Standards and Technology (NIST) have created a new approach for electronic n...

Florida's 'worm grunters' collect bait worms by inadvertently imitating mole sounds

...nd wait for thunderstorms. Even in very heavy downpours, only 1-2 worms came out in an hour. That seemed to rule out the hypothesis that worm grunting mimics the sound of rainfall. Finally, Catania compared the vibrations produced by worm grunting and those of a mole burrowing. "The moles are quite noisy....

Egg whites solve the 3-D problem

...ies are seeking to develop three-dimensional cell culture systems that allow them to test their new techniques and drugs in a system that more closely mimics the way in which cells grow. However, a big sticking point is the cost of commercial media for growing such cultures. Dr. Steffi Oesterreich, assoc...

The dietary supplement genistein can undermine breast cancer treatment

...r prevent its recurrence should think twice before also taking a soy-based dietary supplement, researchers report. Genistein, a soy isoflavone that mimics the effects of estrogen in the body, can negate the effectiveness of aromatase inhibitors, which are designed to reduce the levels of estrogens that c...

Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering

...What most people have done is try to promote the cell differentiation through adding soluble factors to cell culture. Nothing has been developed that mimics how the extracellular matrix morphs over time. And, this matrix is known to play a large role in cell survival and fate." "If you can better mimic ...
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