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Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

Philadelphia (July 27, 2009) DLX5, a gene crucial for embryonic development, promotes cancer by activating the expression of the known oncogene, MYC, according to researchers from Fox Chase Cancer Center. Since the DLX5 gene is inactive in normal adults, it may be an ideal target for future anti-...

Mystery E. coli genes essential for survival of many species

Scientists have shown that E. coli one of the best known and extensively studied organisms in the world remains an enigma that may hold the key to human diseases, such as cancer. The team, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and based at the Univers...

Rutgers study finds many consumers ignore food product recalls

NEW BRUNSWICK, N.J. Rutgers' Food Policy Institute (FPI) released a study today showing that many Americans fail to check their homes for recalled food products. Only about 60 percent of the studied sample reported ever having looked for recalled food in their homes, and only 10 percent said they...

New models question old assumptions about how many molecules it takes to control cell division

Blacksburg, Va. -- A single cell whether a yeast cell or one of your cells is exquisitely sensitive to its surroundings. It receives input signals, processes the information, makes decisions, and issues commands for making the proper response. As with any control system, noise errors, slip-ups,...

Vaccines and autism: Many hypotheses, but no correlation

An extensive new review summarizes the many studies refuting the claim of a link between vaccines and autism. The review, in the February 15, 2009 issue of Clinical Infectious Diseases and now available online, looks at the three main hypotheses and shows how epidemiological and biological stud...

Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases

JACKSONVILLE, Fla. A Mayo Clinic-led international consortium has found a mechanism that may help explain Parkinson's and other neurological disorders. Studying just eight families worldwide, the international team of researchers have discovered a genetic defect that results in profound depre...

In many fungi, reproductive spores are remarkably aerodynamic

CAMBRIDGE, Mass., Dec. 23, 2008 -- The reproductive spores of many species of fungi have evolved remarkably drag-minimizing shapes, according to new research by mycologists and applied mathematicians at Harvard University. In many cases, the scientists report this week in the Proceedings of th...

Nitrate concentrations of ground water increasing in many areas of the United States

MADISON, WI, SEPTEMBER 15, 2008Nitrate is the most common chemical contaminant in the world's ground water, including in aquifers used for drinking-water supply. Nitrate in drinking water of the United States is regulated by the U.S. Environmental Protection Agency (USEPA) because of concerns rela...

Researchers identify cancer-causing gene in many colon cancers

BOSTON--Demonstrating that despite the large number of cancer-causing genes already identified, many more remain to be found, scientists at Dana-Farber Cancer Institute have linked a previously unsuspected gene, CDK8, to colon cancer. The discovery of CDK8's role in cancer was made possible by ...

Fungi the cause of many outbreaks of disease but mostly ignored

Fungi can cause a number of life-threatening diseases but they also are becoming increasingly useful to science and manufacturing every year. However, many people, scientists among them, are largely unaware of the roles fungi play in the world around us. Research on fungi and fungal diseases are ...

First draft of transgenic papaya genome yields many fruits

A broad collaboration of research institutions in the U.S. and China has produced a first draft of the papaya genome. This draft, which spells out more than 90 percent of the plants gene coding sequence, sheds new light on the evolution of flowering plants. And because it involves a genetically mo...

Variety is the spice of life: too many males, too little time...

Female Australian painted dragon lizards are polyandrous, that is, they mate with as many males as they can safely get access to. This promiscuous behaviour is often found in species where male quality is dubious and there are high levels of infertility in the male population. Female painted drago...

Biomass production -- careful planning can bring many benefits

One way of supplying energy is to grow plant material and burn it. If managed well most of the carbon released by burning the material will be captured by the growing plants, and so have a low impact on overall levels of atmospheric carbon dioxide. Better still, the growing plants could be used...

Why do so many species live in tropical forests and coral reefs?

The latest development in a major debate over a controversial hypothesis of biodiversity and species abundance is the subject of a paper to be published in the 1 November 2007 issue of the journal Nature. The authors report good agreement between the species richness of two of the world's most vu...

Scientists unveil structure of molecular target of many drugs

More than 40 years after beta blockers were first used clinically, scientists can finally get a detailed, three-dimensional look at the drugs molecular targetthe beta2-adrenergic receptor. This receptor hails from a family of proteins called G protein-coupled receptors (GPCRs) that control critica...

Dead clams tell many tales

Inventories of living and dead organisms could serve as a relatively fast, simple and inexpensive preliminary means of assessing human impact on ecosystems. The University of Chicago's Susan Kidwell explains how measuring the degree of live-dead mismatch could be used as an ecological tool in the ...

Analysis of breast and colon cancer genes finds many areas of differences between tumors

Researchers from University Hospitals (UH) Ireland Cancer Center and Case Western Reserve University School of Medicine are part of a new national study that has analyzed more than 18,000 genes, including 5,000 previously unmapped genes, from breast and colorectal tumors. The study, published onl...

Data on life expectancy show many countries clustered in high mortality traps

Boston, MA -- Growing recognition of the importance of health as a contributing factor to economic development and societal change has prompted the Proceedings of the National Academy of Sciences (PNAS) to add a new subsection in Sustainable Health to its existing section on Sustainable Developmen...

Using evolution, UW team creates a template for many new therapeutic agents

MADISON - By guiding an enzyme down a new evolutionary pathway, a team of University of Wisconsin-Madison researchers has created a new form of an enzyme capable of producing a range of potential new therapeutic agents with anticancer and antibiotic properties. Writing in the current issue (Sep...

One species, many genomes

Faster growth, darker leaves, a different way of branching - wild varieties of the plant Arabidopsis thaliana are often substantially different from the laboratory strain of this small mustard plant, a favorite of many plant biologists. Which detailed differences distinguish the genomes of strains...

For many insects, winter survival is in the genes

Many insects living in northern climates don't die at the first signs of cold weather. Rather, new research suggests that they use a number of specialized proteins to survive the chilly months. These so-called "heat-shock proteins" ensure that the insects will be back to bug us come spring. ...

Warts vaccine -- 1 of many in pipeline

A clinical trial treating the papillomaviruses responsible for genital warts was on target at the halfway mark, according to Australian of the Year 2006 Professor Ian Frazer and trial manager, sexual health specialist Dr David Jardine More than 200 patients in China and Australia have taken part...

Despite their heft, many dinosaurs had surprisingly tiny genomes

They might be giants, but many dinosaurs apparently had genomes no larger than that of a modern hummingbird. So say scientists who've linked bone cell and genome size among living species and then used that new understanding to gauge the genome sizes of 31 species of extinct dinosaurs and birds, ...

Study finds mercury prevalent in many western fish

A new survey by researchers at Oregon State University and the U.S. Environmental Protection Agency of more than 600 rivers and streams in the western United States found widespread mercury concentrations in fish. Though few of the more than 2,700 fish analyzed in the study contained alarmingly h...

Successful lung cancer surgery not enough to break nicotine dependence in many smokers

A new study has found that close to half of 154 smokers who had surgery to remove early stage lung cancer picked up a cigarette again within 12 months of their potentially curative operation, and more than one-third were smoking at the one year mark. Sixty percent of patients who started smoking a...

How many genes does it take to learn? Lessons from sea slugs

Scientists analyzing the genomics of a marine snail have gotten an unprecedented look at brain mechanisms, discovering that the neural processes in even a simple sea creature are far from sluggish. At any given time within just a single brain cell of sea slug known as Aplysia, more than 10,000 ...

Chemical in many air fresheners may reduce lung function

New research shows that a chemical compound found in many air fresheners, toilet bowl cleaners, mothballs and other deodorizing products, may be harmful to the lungs. Human population studies at the National Institute of Environmental Health Sciences (NIEHS), a part of the National Institutes of He...

Dogs keep dying: Many owners unaware of toxic dog food

Even though Diamond, Country Value and Professional brand dog foods have been recalled for containing highly toxic aflatoxins, they have caused at least 100 dog deaths in recent weeks, say Cornell University veterinarians, who are growing increasingly alarmed. Some kennels and consumers around the ...

From one cell, many possible cures

A single cell with the potential to repair damaged heart muscle tissue . . . regenerate injured bone . . . create new cartilage or skin . . . even reverse nerve damage. Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other hu...

Many needles, many haystacks

Most of what happens in cells is the work of machines that contain dozens of molecules, chiefly proteins. With the completion of human and other genomes, researchers now have a nearly complete "parts list" of such machines; what's lacking now is the manual telling where all the pieces go. A new stu...

New study shows patients more willing to consider self-injectable HIV therapy than many physicians anticipate

Initial results from the OpenMind study, the largest behavioural study to look at both patients' and physicians' perceptions of HIV care in treatment-experienced patients, were revealed today at EACS. The study's findings are anticipated to help physicians implement improved care to HIV patients an...

Trio of plant genes prevent 'too many mouths'

A signaling pathway required for plants to grow to their normal size appears to have an unexpected dual purpose of keeping the plant from wallpapering itself with too many densely clustered stomata. "It's surprising that size and stomata patterning ?both key to plants being able to survive on dry...

Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades

Growing desertification worldwide threatens to swell by millions the number of poor forced to seek new homes and livelihoods. And a rising number of large, intense dust storms plaguing many areas menace the health of people even continents away, international experts warn in a new report. Thick s...

Improved statistical tools reveal many linked loci

An innovative new statistical method, described in the open-access journal PLoS Biology, streamlines the computation required to identify all the potential locations in the genome that influence a particular physical trait, or phenotype. Thanks to the new method developed by John Storey, Joshua M. ...

Simple drug has the potential to save many lives threatened by malaria

A simple drug, given to children with severe malaria before they reach hospital, has the potential to save many lives, say researchers in this week's BMJ. Every year over a million children die of malaria in Africa. The majority of fatalities occur outside hospital, especially in rural areas. Fo...

Same mutation aided evolution in many fish species, Stanford study finds

After decades of laboratory work studying how animals evolve, researchers sometimes need to put on the hip waders, pull out the fishing net and go learn how their theory compares to the real world. According to a Stanford University School of Medicine study published in the March 25 issue of Scienc...

Ancient olfaction protein is shared by many bugs, offering new pest control target

In the battle against insect pests, new research indicates that it may all come down to the sense of smell. A group of Rockefeller University scientists who had previously identified a key gene essential for the sense of smell in fruit flies now shows that this gene's function appears to be evoluti...

UW's Rosetta software to unlock secrets of many human proteins

University of Washington TechTransfer recently licensed software that will give scientists a huge advantage in the fight against disease. The software, known as Rosetta, predicts how proteins fold, information that is highly valuable to biological and biomedical researchers. UW Tech Transfer's Digi...

The hepatitis healing power of blueberry leaves

..., Kataoka and colleagues noted its effective concentration against HCV was 100 times less than the toxic threshold, and similar chemicals are found in many edible plants, suggesting it should be safe as a dietary supplement. In the meantime, the researchers now hope to explore the detailed mechanisms of h...

Advances in lung cancer research announced at conference

...event lung cancer from spreading to the brain. In non-small cell lung cancer (NSCLC), brain metastasis is a devastating complication that occurs in as many as 1 in 4 patients. The ability to identify those at risk for developing brain metastasis may guide new therapies. A team led by Dr. Weiss found se...
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