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Key to 'curing' obesity may lie in worms that destroy their own fat: McGill researchers

This release is available in French . A previously unknown mutation discovered in a common roundworm holds the promise of new treatments for obesity in humans, McGill University researchers say. Their study was published Dec. 3 in the journal Nature , and was funded by the Canadian Cance...

Holding breath for several minutes elevates marker for brain damage

...ng. The nine competitive divers formed the experimental group, while the non-divers acted as the controls. The researchers told the participants to lie on their backs on a cot and hold their breath for as long as possible. The conditions were dry, but mimicked a static apnea dive in which the divers f...

August 2009 Geology and GSA Today media highlights

...gy and Geophysics, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA. Pages 679-682. Global observations indicate that the faults that lie between tectonic plates slip far more easily than is predicted based on measurements of rock strength. The cause of this mechanical weakness may be a ...

UC San Diego engineer provides insights to decades-old DNA squabble

...ath along the chromatin axis such that adjacent nucleosomes along the chain lie side by side on the chromatin fiber also and thus the linker DNA connecting...ng the chromatin fiber such that adjacent nucleosomes on the chain actually lie on opposite sides of the fiber such that the linker DNA is straight. (The n...

New windows opened on cell-to-cell interactions

...he surface of every cell is a forest of molecules to induce interactions. These proteins need to rise from the forest. What allows them to stick up or lie down? We've really had a poor idea of what's going on. Knowing the genome and what proteins are there is crucially important, but that information in ...

Warming climate threatens California fruit and nut production

...y poorly understood, might point to additional strategies to manage tree dormancy, which will help growers cope with the agro-climatic challenges that lie ahead, the researchers suggested. ...

Children's Hospital of Pittsburgh of UPMC scientists identify enzyme important in aging

... PITTSBURGH, July 10 The secret to longevity may lie in an enzyme with the ability to promote a robust immune system into old age by maintaining the function of the thymus throughout life, according to r...

Exploring standards to advance microbial genomics

...be done with microbial genomics, according to DOE JGI Genome Biology head Nikos Kyrpides, if researchers would embrace the world of possibilities that lie beyond the present anthropocentric focus and would also institute shared standards for genomic data collection and analysis. In a perspective piece ...

The sound of light: Innovative technology shatters the barriers of modern light microscopy

...tissue to ascertain whether they are healthy or diseased or to investigate cell function. However, the penetration limits for this kind of examination lie between half a millimeter and one millimeter of tissue. In thicker layers light is diffused so strongly that all useful details are obscured. Toget...

Protein regulates movement of mitochondria in brain cells

...ues are now investigating the role that HUMMR may play in stroke models, particularly whether or not this activity helps protect vulnerable cells that lie just outside the core areas of the brain that are damaged by stroke. "Ultimately, these advances in our understanding of the molecular and cell b...

Scholar unconvinced new lie-detection methods better than old ones

... a suspect in custody, out comes the polygraph, or lie detector. But in today's forensically sophistic...ave been hailed as the next, best technologies for lie detection in America, particularly in the context ... But, Littlefield said, using the old-fashioned lie detector, "you're not really getting deception so ...

EMBL scientists develop first fully automated pipeline for multiprotein complex production

... Most cellular processes are carried out by molecular machines that consist of many interacting proteins. These protein complexes lie at the heart of life science research, but they are notoriously hard to study. Their abundance is often too low to extract them directly from cells an...

Researchers discover primer to plant defense system

...aplinski acknowledged that this field is in its infancy and involves a very complex network of responses, he and co-authors are excited about what may lie ahead. "Long term, this discovery may prove useful for preventing diseases in crops and other plants, and perhaps for generating plants that are mo...

Satellite snow maps help reindeer herders adapt to a changing Arctic

...ow maps. "Snow is of paramount importance for reindeer herding because its quality determines whether reindeer are able to access the pastures that lie beneath it for much of the year," said Anders Oskal, the Director of the International Centre for Reindeer Husbandry (ICR). "Detailed circumpolar snow...

Difference in fat storage may explain lower rate of liver disease in African-Americans

...in resistance among all groups are the same, researchers found. "This presents something of a paradox," Dr. Browning said. The explanation might lie in where different ethnic groups typically store fat. Obese Hispanics tend to deposit fat in the liver and visceral adipose tissue the area around...

MIT: Why we have difficulty recognizing faces in photo negatives

...negatives. The study, which appears in the Proceedings of the National Academy of Sciences this week, suggests that a large part of the answer might lie in the brain's reliance on a certain kind of image feature. The work could potentially lead to computer vision systems, for settings as diverse as ...

RNA research strategy for Europe takes shape

... research in RNA over the next ten years. Three earlier workshops had examined various aspects of RNA research to identify where gaps in our knowledge lie and what is required to plug these gaps and fulfil the promise that RNA holds. Forward Looks are a key part of ESF's work, examining important areas o...

Relationships in rank and file

...s like BLAST evaluate the similarity between a pair of sequences by aligning them underneath each other in such a way that similar amino acids come to lie in the same columns. The sequence similarity is then calculated by adding the similarities of all aligned amino acids. Here, the similarity between am...

Rett Syndrome Research Trust advisor makes significant discovery

...al to the health of neurons. Since MECP2 is located on the X chromosome, girls with Rett Syndrome are mosaic: cells with a healthy copy of the gene lie side by side with cells that have the mutated version. Mandel and colleagues found that MECP2- deficient astrocytes could not sustain normal neuronal ...

Honest crabs, power to the hungry, nice mice and clever meerkats: News from the American Naturalist

...acey@press.uchicago.edu . HOW OFTEN DO ANIMALS lie ABOUT THEIR INTENTIONS? An article by Princeto...r intentions. Some models suggest that animals may lie about their intentions up to 40 percent of the tim... findings, Lairde says, suggest that animals don't lie about their actions nearly as much as theorists on...

Shark attacks decline worldwide in midst of economic recession

... as the group most likely to be affected by economic hardship, Burgess said. "These are sort of the average folks that go to the water for recreation, lie on the beach, work on their suntan and take their kids in the surf for a swim," he said. "I would expect their numbers to decline in 2009." Over th...

Childhood chicken pox could affect oral health years later

... could lead to serious (and irreversible) oral health problems such as herpes-type lesions and severe bone damage to the jaws. Varicella zoster can lie dormant in the body for decades, and if activated can lead to herpes zoster (HZ), more commonly referred to as shingles, according to a study that app...

Biofuels boom could fuel rainforest destruction, Stanford researcher warns

... the global environment," Gibbs said. "As we look toward biofuels to help reduce climate change we must consider the rainforests and savannas that may lie in the pathway of expanding biofuel cropland." The FAO is in the process of collecting and interpreting the data for the current decade. "This will ...

Tailor-made recombinant proteins in mammals

...ally modifying part of its structure known as the Fc fragment. Conventionally this is done by targeting lysines, but there are many of these, and some lie near sites that, if modified, would cripple the antibody instead of making it therapeutic. Bertozzi's group proved they could precisely tag the Fc ...

Mayo Clinic researchers suspect a novel gene is causing restless legs syndrome in a large family

...ug therapy," he says. They can also trace the molecular route from the gene mutation to the disorder, and see if the other loci linked to the syndrome lie along this pathway. So far, no one has found a definitive link between restless legs syndrome and a specific gene mutation, but large families hold th...

Caltech researchers help unlock the secrets of gene regulatory networks

...ene regulatory networks of a variety of organisms, including fruit flies, soil-dwelling nematodes, sea urchins, lampreys, and mice. "These networks lie at the heart of the regulatory apparatus, and they consist of genes that encode proteins that regulate other genes, and the DNA sequences which contro...

Salk researchers develop novel glioblastoma mouse model

...mulate a disease but never fully capture the molecular complexity underlying disease in humans." Trying to mimic randomly occurring mutations that lie at the heart of all tumors, the Salk researchers used modified viruses to shuttle cancer-causing oncogenes into a handful of cells in adult mice. Thei...

Brain background to body mass

...d are likely to influence brain function." Increase in weight occurs when calories taken in exceed calories burned, but behind that simple equation lie behavioural processes such as appetite and satiety, as well as the biochemical mechanisms our bodies use to process foods and use stores of energy, su...

Genes for 9 health indicators

...vered. Work underway, such as The 1000 Genomes Project and wider population studies, will help to determine whether the additional genetic effects lie in many common variants with relatively small effect or in rare variants with a larger effect. ...

New papers offer insights into process of malarial drug resistance

...ting offering uneven results, two new papers by University of Notre Dame biologist Michael Ferdig suggest that the means of combating this old foe may lie in the new tools of genomics and bioinformatics. In the papers, Ferdig points out that development of the malaria parasite Plasmodium falciparum in t...

Lab test for allergy scoops national

...er for the event was Professor W Angus Wallace, Professor of Orthopaedic and Accident Surgery at The University of Nottingham, whose special interests lie in the fields of shoulder surgery, sports injuries, osteoporosis, biomechanics and research into passenger safety in aircraft and cars. Guests include...

New gene-silencing pathway found in plants

... getting down to business. Following a hunch, postdoctoral scholar Andrzej Wierzbicki decided to take a closer look at the stretches of DNA that lie between genes, the so-called intergenic regions. Biologists have long been baffled by this alleged "junk DNA" because transcription seems to occur he...

Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord

...t demonstrated robust Schwann cell remyelination after bone marrow stromal cell injection," reported Dr. Hunt. "An important difference in results may lie in the distinct methodologies used to culture MSCs." Although MSCs may possess neural differentiation capabilities in vitro, their in vivo behavior i...

Sarcospan, a little protein for a big problem

... and then disappear after the first few weeks of life. Mouse muscle cells were protected by sarcospan, but the true importance of this discovery will lie in its potential for human therapeutics, specifically gene therapy. In that regard, sarcospan's small gene size is significantat 600 bp, it is easily ...

Stanford researchers: Global warming is killing frogs and salamanders in Yellowstone Park

...of global warming are even more profound and are happening more rapidly than previously anticipated," the researchers wrote. The disappearing ponds lie in picturesque northern Yellowstone, specifically the lower Lamar Valley, which holds dozens of small fishless ponds where the habitat has been ideal ...

Moderate use averts failure of type 2 diabetes drugs in animal model

.... Examination of the pancreas showed that the animals' beta cells were still alive and contained normal levels of insulin. "The problem seems to lie somewhere between the trigger for secreting insulin, which was hyperactivated while they were on the medication, and the actual mechanisms that releas...

Indiana University research at American Public Health Association meeting

... amount that they smoke. Rather than changing smokers' own attitudes about smoking, the influence of the policies, particularly the strong ones, might lie more in changing smokers' perceptions of other people's attitudes about smoking -- changing the perceived social norms, according to an Indiana Univer...

UCSB study finds physical strength, fighting ability revealed in human faces

...ce of men. "The next step is to isolate what it is in the face that indicates upper body strength," said Sell. He suggests that the correlation may lie in the heavier brow ridge and thicker jaw that result from increased levels of testosterone. "Many studies have been done on the effects of testostero...

Florida's 'worm grunters' collect bait worms by inadvertently imitating mole sounds

...hy the technique works. But Catania, an associate professor of biological sciences at Vanderbilt who studies moles, thought that the explanation might lie in Darwin's remark: "It is often said that if the ground is beaten or otherwise made to tremble worms will believe that they are pursued by a mole and...

Europe rallies behind nanotechnology to wean world from fossil fuels

...ase," said Kasemo."This will push prices down and make solar electricity more and more competitive." Some of the most exciting of these alternatives lie in the field of biomimetics, which involves mimicking processes that have been perfected in biological organisms through eons of evolution. Plants and...
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