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When cancer cells can't let go

Like a climber scaling a rock face, a migrating cancer cell has to keep a tight grip on the surface but also let go at the right moment to move ahead. Chan et al. reveal that the focal adhesion kinase (FAK) coordinates these processes to permit forward movement. The study will be published online ...

Runners -- Let thirst be your guide

Many people are drinking too much water, including sports drinks, when exercising, a practice that could put some individuals engaging in prolonged types of endurance exercise at risk of potentially lethal water intoxication, say international experts who study disorders of water metabolism. Such ...

Scientists find mutations that let bird flu adapt to humans

By comparing influenza viruses found in birds with those of the avian virus that have also infected human hosts, researchers have identified key genetic changes required for pandemic strains of bird flu. The new work, reported in the Nov. 16 issue of the journal Nature, illustrates the genetic ch...

'Prosthetic' retinal cells let blind mice see light

In an experiment that could offer a new pathway to restoring vision in people with inherited retinal degeneration, researchers have engineered cells in the eye to be light sensitive that were not before. Using a harmless virus, they introduced a gene for a light-sensitive protein into "inner retina...

Argonne to showcase science and technology at community open house

... The educational event will feature interactive exhibits, hands-on demonstrations, engaging presentations and tours of Argonne's unique facilities. let your imagination soar as you learn about the wonders of science, explore technology innovation and experience Argonne's research firsthand with experi...

DNA computation gets logical at the Weizmann Institute of Science

...le bound to a second protein which keeps the light covered. A specialized enzyme, attracted to the site of the correct answer, removed the 'cover' and let the light shine. The tiny water drops containing the biomolecular data-bases were able to answer very intricate queries, and they lit up in a combinat...

Opening a new window on daylight

... A new approach to windows that could let in more light and cut indoor lighting needs by up to 99% in buildings in Tropical regions without losing the cooling effect of shades. Details are rep...

Silicon with afterburners: Process developed at Rice could be boon to electronics manufacturer

...nice entry point for molecules into the silicon industry. We can go to a manufacturer and say, 'Let us make your fabrication line work for you longer. let us complement what you have.' "This gives the Intels and the Microns and the Samsungs of the world another tool to try, and I guarantee you they'll...

Life on Earth came from other planets

...e the theory of "abiogenesis" also known as the "organic soup." In the Judeo-Christian Bible, the story of Genesis, it is stated: "And God said, let the earth bring forth the living creature after his kind, cattle, and creeping thing, and beast of the earth after his kind: and it was so." As summed...

Reading the brain without poking it

... SALT LAKE CITY, June 29, 2009 Experimental devices that read brain signals have helped paralyzed people use computers and may let amputees control bionic limbs. But existing devices use tiny electrodes that poke into the brain. Now, a University of Utah study shows that brain sig...

Caltech researchers explore how cells reconcile mixed messages in decisions about growth

...y need a higher level of growth factor before they will divide." The relationships between these competing influences "are really striking when you let them play out" under the influence of cell geography, says Asthagirithat is, when the cells grow as a multicellular cluster. The reality is that not a...

Researchers from around the globe coming to K-State June 21 for workshop on Fusarium fungus

...d answer questions of more than 100 years standing while, at the same time, raising a whole new set of questions that scientists never dreamed to ask, let alone answer. "Many problems arose because different species looked the same," Leslie said. "As you begin to tell those species apart with the DNA-...

Flexible solar strips light up campus bus shelter

...hn Hodgins Engineering Building and the Life Sciences Building. "Our goal is to provide a clean, affordable power source for bus shelters that will let transit companies run Internet-based scheduling updates," said Adrian Kitai, a professor of engineering physics at McMaster who guided the project. "...

First jaguar photo taken at Smithsonian Research Station in Panama

...ional group, Panthera, is using camera traps to monitor jaguars on the mainland. "These cats are incredibly elusive and sightings on the mainland, let alone Barro Colorado Island, are extremely rare," said Jackie Willis. "This is what makes this photo so excitingit offers proof positive that despite ...

Star Trek-like technology offers noninvasive monitor for patients and athletes

...t risk for cardiovascular collapse," said Soller, who leads NSBRI's Smart Medical Systems and Technology team. "The measurement of metabolic rate will let astronauts know how quickly they are using up the oxygen in their life-support backpacks. If spacewalking astronauts run low on oxygen, the situation ...

Analysis finds strong match between molecular, fossil data in evolutionary studies

...versity of Chicago paleontologist David Jablonski fielded a hostile question: Why bother classifying organisms according to their physical appearance, let alone analyze their evolutionary dynamics, when molecular techniques had already invalidated that approach? With more than a few heads in the audie...

Grouping muscles to make controlling limbs easier

...ur experiment tried to do." Using both analytical approaches and techniques from control theory, the researchers chose the muscle combinations that let the frog's hind leg do what it wants to do most effectively. The simulation showed that by choosing the most effective balance of muscle synergies, th...

Risk of vibration-induced vascular injuries linked to vibration frequency differences

...moother than the slower vibrations of an electric hand drill (approximately 63 Hz) and therefore are less likely to cause users discomfort. Don't let that fool you into not using protective devices that can reduce your exposure to vibration, she says. The new research study conducted at the National...

Poison: It's what's for dinner

...ity of Utah biologists have narrowed the hunt for detoxification genes that let the rodents eat toxic creosote bushes that replaced juniper. "It was ei... Dearing says that as creosote invaded, some woodrats already had genes to let them eat creosote or there was a mutation in existing detoxification genes ...

Desert woodrats switch one dietary poison for another

...ood. Now biologists have narrowed the hunt for detoxification genes that let the rodents eat the toxic creosote bushes that replaced junipers. "It wa... Dearing says that as creosote invaded, some woodrats already had genes to let them eat creosote, or there was a mutation in existing detoxification genes...

Research could lead to new non-antibiotic drugs to counter hospital infections

...hicago, hypothesized that phosphate depletion in the stressed intestinal tract signals P. aeruginosa to become lethal. To test this theory, they let worms (Caenorhabditis elegans) feed on "lawns" of P. aeruginosa and Escherichia coli grown in both low-phosphate and high-phosphate media. Only the ...

Desert woodrats switch one dietary poison for another

...ood. Now biologists have narrowed the hunt for detoxification genes that let the rodents eat the toxic creosote bushes that replaced junipers. "It wa... Dearing says that as creosote invaded, some woodrats already had genes to let them eat creosote, or there was a mutation in existing detoxification genes...

Spring fishing season arrives... and with it, amphibian diseases

...ranaviruses and Bd, and conducted surveys of anglers to determine how often tiger salamanders are used as bait, and how frequently the salamanders are let go in fishing waters. The scientists also organized bait-shop surveys to determine whether tiger salamanders are released back into the wild after...

Poison: It's what's for dinner

...ity of Utah biologists have narrowed the hunt for detoxification genes that let the rodents eat toxic creosote bushes that replaced juniper. "It was ei... Dearing says that as creosote invaded, some woodrats already had genes to let them eat creosote or there was a mutation in existing detoxification genes ...

NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces

...ks as "black-or-white stencils" to remove either all or none of the photoresist according to a set pattern. The "white" parts of the patternthose that let light throughare then etched to a single depth into the substrate. Grayscale photolithography, on the other hand, uses "shades of gray" to activate an...

New simulation shows consequences of a world without Earth's natural sunscreen

...hers then increased the emission of CFCs and similar compounds by 3 percent per year, a rate about half the growth rate for the early 1970s. Then they let the simulated world evolve from 1975 to 2065. By the simulated year 2020, 17 percent of all ozone is depleted globally, as assessed by a drop in Do...

Arctic governments and industry still unprepared for oil spills 20 years after Exxon Valdez

...en's livelihoods were destroyed, many wildlife and fish populations still haven't recovered and the Alaskan economy lost billions of dollars. We can't let that happen again in Alaska's productive waters." ...

The 'clean plate club' may turn children into overeaters

...We Think. He recommends that parents provide moderate portions of a variety of foods, encouraging the child to at least try all of the foods, and let them decide whether they want additional servings. ...

Understanding natural crop defenses

...mited resources. Mutated Arabidopsis seedlings that no longer responded to far-red radiation but had normal levels of the far-red photoreceptor, still let their defenses down. At closer inspection, the researchers found that far-red radiation decreased the plants' sensitivity to jasmonates. By ignoring j...

How Volvox got its groove

...es and is one of the costs of cooperation. "So now there's a temptation to cheat," Herron said. "Let's say I'm in a four-cell colony. I'm going to let the other three guys make the extracellular matrix, and I'm going to focus on growing and reproducing. That's the conflict." Overcoming that confli...

Weizmann Institute scientists discover how cancer cells survive a chemotherapy drug

...d allow them to cast a wide net on the one hand to sift through the numerous cellular proteins that could conceivably affect survival but that would let them zoom in on the activities of individual cells in detail, on the other. Letting the computer take over the painstaking work of searching for anoma...

Virtual reality: Keyhole surgeons training could help meet European working time directives

...nt, as well as newly qualified doctors who are at the beginning of their surgical careers. The Royal College of Surgeons runs training courses that let a surgeon see what a procedure involves. With the arrival of desktop computing that has high graphic capability, software developers have built progra...

Researchers to use K-State's BSL-3 Lab for $1 million study of fungus threatening wheat crops

... have narrowed down a few Kansas varieties in the laboratory, they will further test the resistance by planting them in a test field in Brazil. "We'll let the fungus find our varieties naturally," Valent said. The third aspect of the project involves sharing findings about wheat blast with stakeholder...

Cell 'anchors' required to prevent muscular dystrophy

....D., a postdoctoral fellow in the Bennett laboratory, devised a method that let researchers manipulate gene expression in a specific section of adult muscle, rather than in the whole animal. "This development let us look right away at what happened in adult mice when we produced ankyrin ...

Reverse evolution in real-time

... In his book, Wonderful World, Stephen Jay Gould writes about an experiment of 'replaying life's tape', wherein one could go back in time, let the tape of life play again and see if 'the repetition looks at all like the original'. Evolutionary biology tells us that it wouldn't look the same ...

Protein that regulates hormones critical to women's health found in pituitary

...mone release," says Jackson. "Unlike other synaptotagmins, Syt IV tunes the triggering command and determines whether the same electrical impulse will let a large or small amount of hormone out of the nerve terminal." This ability to modulate hormone release may have important implications for pregn...

Tellme Enters Automotive Market

...ally improves how people use the phone to get the information they need every day. By combining Internet data and a voice interface, Tellme's services let people simply say what they want and get it. Services running on Tellme's platform include business search on 411 and information search on 1-800-555-...

Viruses, start your engines!

...f the techniques, x-ray crystallography, showed the ordered arrays of atoms in the various structures, while another, called cryo-electron microscopy, let the researchers study the broader shape of the structures without the need for coating or drying out the specimens. Having already determined the s...

Our unconscious brain makes the best decisions possible

...ly good decision makers after all, just not quite so good at doing it consciously. Kahneman explicitly told his subjects what the chances were, but we let people's unconscious mind work it out. It's weird, but people rarely make optimal decisions when they are told the percentages up front." Pouget anal...

Princeton researchers discover new type of laser

...0%, said Franz. This could potentially allow the device to run at lower currents, and also makes it less vulnerable to temperature changes. "It should let us dramatically improve laser performance," he said. The device used in the study does not fully attain this level of performance, because the conv...
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