The very unexpected life and death of a leukemic cell
B cell chronic lymphocytic leukemia (CLL) is an incurable disease in which cells in the bone marrow grow and survive to the point where they become abnormal and malignant (leukemic). The progression of the disease is slow and there has been a lack of information regarding the rate of production of CLL cells, and the time-course of their death. For years, doctors and scientists believed th...Unexpected lock and key mechanism found for the assembly of tumor blood vessels
A critical lock and key mechanism that allows the final step in the completion of new blood vessel formation has been identified by a University of California, San Diego (UCSD) School of Medicine team in research that promises to lead to a new way to halt tumor growth by cutting off the tumor blood supply. The research team led by Judith Varner, Ph.D., Associate Professor of Medicine at UC...Retina adapts to seek the unexpected, ignore the commonplace
Researchers at Harvard University have found evidence that the retina actively seeks novel features in the visual environment, dynamically adjusting its processing in order to seek the unusual while ignoring the commonplace. The scientists report in this week's issue of the journal Nature on their finding that this principle of novelty-detection operates in many visual environments. "Appar...Tissue regeneration operates differently than expected
Max Planck researchers in Bad Nauheim discover the mechanism by which adult stem cells are integrated into skeletal or heart muscle tissue. There is disagreement, however, about the mechanism on which repair processes are based. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, in co-operation with colleagues from Martin Luther University in Halle...UF scientist finds unexpected link between cat and human AIDS viruses
Emerging relationships between the two viruses could one day lead to a vaccine for human A University of Florida researcher has discovered an unexpected link between the viruses that cause feline and human AIDS: Cats vaccinated with an experimental strain of the human AIDS virus appear to be at least as well-protected against the feline version of the disease as those immunized with the v...Mouse genome much more complex than expected
Over 100 scientists worldwide publish joint study in Science More than 100 scientists from Australia, Asia, Europe and the US have been probing the genome of the mouse in a joint study lasting several years. Their results in some aspects have completely overturned geneticists' traditional assumptions. The findings are available in the prestigious journal Science on 2nd September. The gene...Enzyme crystal structure reveals 'unexpected' genome repair functions
The study is being published in an advance online version of the journal Molecular Cell. The research looked at XPB helicase from an archaea, a single cell organism similar to bacteria. Helicases are enzymes that unwind or separate the strands of the nucleic acid double helix, an action that is critical to transcription and nucleotide excision repair (NER), as well as other cell processes...Scientists find Antarctic ozone hole to recover later than expected
Scientists from NASA and other agencies have concluded that the ozone hole over the Antarctic will recover around 2068, nearly 20 years later than previously believed. Researchers from NASA, the National Oceanic and Atmospheric Administration (NOAA) and the National Center for Atmospheric Research (NCAR) have developed a new tool, a math-based computer model, to predict the timing of ozone...Food-crop yields in future greenhouse-gas conditions lower than expected
Open-air field trials involving five major food crops grown under carbon-dioxide levels projected for the future are harvesting dramatically less bounty than those raised in earlier greenhouse and other enclosed test conditions ?and scientists warn that global food supplies could be at risk without changes in production strategies. The new findings are based on on-going open-air research a...Wolves are suffering less from inbreeding than expected
Increasing levels of inbreeding is a threat against the viabi lity of the Scandinavian wolf population. A study just coming out in the new journal PLoS ONE now demonstrates that inbreeding is not affecting the wolves as badly as expected. The results show that it is the most genetically variable wolf individuals that are recruited into the breeding population. An important consequence of this act...Cheaper, better disease treatments expected from faster approach to developing antibodies
A method of mass-producing disease-fighting antibodies entirely within bacteria has been developed by a research group at The University of Texas at Austin. The group led by Dr. George Georgiou developed the new antibody-production approach to improve upon processes used previously to identify new drugs. Drug companies have used those more time- and labor-intensive processes to develop a...St. Jude study shows genes play an unexpected role in their own activation
The “on switch,” a protein called CREB, is a transcription factor—a molecule that binds to a section of DNA near a gene and triggers that gene to make t...