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Specific genetic cause of fetal alcohol-related developmental disorders found

Alcohol consumption by pregnant women hinders brain development in their children by interfering with the genetic processes that control thyroid hormone levels in the fetal brain, a new animal study found. Results will be presented Wednesday at The Endocrine Society's 91st Annual Meeting in Washin...

Psychiatric disorders are common in adults who have had anorexia

The study was initiated in 1985. A total of 51 teenagers with anorexia nervosa were studied, together with an equally large control group of healthy persons. The groups have been investigated and compared several times as the years have passed. "This study is unique in an international perspecti...

OSA's ISP launches with research on breathing disorders and congenital heart defects

WASHINGTON, Oct. 30 -- Two groups of researchers, one in the United States and one in Australia, are announcing the development of new optical techniques for visualizing the invisible processes at work in several human diseases. The published results are the first to showcase the Optical Society's...

Aberrations in region of chromosome 1q21.1 associated with broad range of disorders in children

Researchers have discovered a submicroscopic aberration in a particular region of human chromosome 1q21.1 that appears to be associated with a variety of developmental disorders in children. The aberration can manifest itself as unexplained mild or moderate mental retardation, growth retardation, ...

IVF does not increase risk of developmental disorders in children

This release is available in Spanish . Barcelona, Spain: Couples who need IVF in order to become pregnant can be reassured that this will not lead to developmental problems in early infancy, a Dutch researcher told the 24th annual conference of the European Society of Human Reproduction ...

Mental disorders are disorders of the brain

Depression, anxiety disorders such as panic disorder and obsessive-compulsive disorders, alcohol and drug dependence, dementia and Parkinsons disease are just a few examples of disorders of the brain. The size, the burden and cost of brain disorders in the EU is immense, and has so far been und...

New research finds possible genetic link to cause of pregnancy loss and disorders

KNOXVILLE -- Scientists at the University of Tennessee, Knoxville, and Lawrence Berkeley National Laboratory (LBNL) have published new findings about a cause of a condition at the root of genetic disorders such as Down Syndrome, pregnancy loss and infertility. Called aneuploidy, the condition i...

A new mouse model provides insight into genetic neurological disorders

Neurosensory diseases are difficult to model in mice because their symptoms are complex and diverse. The genetic causes identified are often lethal when transferred to a mouse. The lack of animal models slows progress in understanding and treating the diseases. By strategically altering a protein-...

Genetic abnormality may increase risk of blood disorders

NEW YORK, March 15, 2009 Researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) have shown for the first time that a tendency to develop some blood disorders may be inherited. Their research, published online today in Nature Genetics , identifies a common genetic sequence abnormality that...

The genetics of fear: Study suggests specific genetic variations contribute to anxiety disorders

Polymorphisms are variations in genes which can result in changes in the way a particular gene functions and thus may be associated with susceptibility to common diseases. In a new study in Psychological Science , a journal of the Association for Psychological Science, psychologist Tina B. Lonsdo...

'Neurological work-arounds' offer hope to people with monoamine-related disorders

Researchers have known for decades that the brain has a remarkable ability to "reprogram" itself to compensate for problems such as traumatic injury. Now, a research article published in the February 2009 issue of the journal Genetics ( http://www.genetics.org ) suggests that the brain may also ...

States expand newborn screening for life-threatening disorders

WHITE PLAINS, N.Y., FEB. 18, 2009 Regardless of where they are born in the United States, nearly all newborns now receive mandated screening for many life-threatening disorders, a remarkable public health advance of the last four years, according to a new report issued today by the March of Dimes...

Scientists uncover evolutionary keys to common birth disorders

Boston-- The work of Forsyth scientist Peter Jezewski, DDS, Ph.D., has revealed that duplication and diversification of protein regions ('modules') within ancient master control genes is key to the understanding of certain birth disorders. Tracing the history of these changes within the proteins ...

Biologists discover link between CGG repeats in DNA and neurological disorders

MEDFORD/SOMERVILLE, Mass. Researchers have long known that some repetitive DNA sequences can make human chromosomes "fragile," i.e. appearing constricted or even broken during cell divisions. Scientists at Tufts University have found that one such DNA repeat not only stalls the cell's replication...

NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders

(New York, Oct. 16, 2008) NARSAD, the world's leading charity dedicated to mental health research, will award its annual prizes tomorrow -- among the most coveted in psychiatry and neuroscience to six prominent scientists whose research in the areas of schizophrenia, bipolar disorder and depres...

Cortisol and fatty liver: Researchers find cause of severe metabolic disorders

A healthy body stores fat in the form of so-called triglycerides in specialized fatty tissue as an energy reserve. Under certain conditions the delicate balance of the lipid metabolism gets out of control and fat is accumulated in the liver, leading to the dreaded fatty liver. This increases the r...

Premature children 4 times more likely to have behavioral disorders

Children born prematurely are four times more likely to have emotional problems or behavioural disorders, according to research led by the University of Warwick. A team led by the University's Department of Psychology and Warwick Medical School examined the behaviour of 200 six-year-old childre...

Hebrew University develops novel approach for treating mitochondrial disorders

A novel concept for the treatment of mitochondrial disorders using directed enzyme replacement therapy (DERT) has won for a Hebrew University of Jerusalem doctoral candidate one of this year's Kaye Innovation Awards. The awards were presented at this year's 71st meeting of the Hebrew University Bo...

Body image program reduces onset of obesity and eating disorders

In their research on eating disorders, Oregon Research Institute (ORI) scientists help young women reduce the influence of the thin ideal, which is described as associating success and happiness with being thin. ORI scientist Eric Stice, Ph.D. and his colleagues have found that their obesity p...

New clinical trial results show how personalized medicine will alter treatment of genetic disorders

WASHINGTON, DC--One of the nations pre-eminent genetic researchers, Eric Hoffman, PhD, of Childrens Research Institute at Childrens National Medical Center, predicts that in relatively short order, medicines next innovation--individualized molecular therapies--will have the unprecedented ability t...

International scientists tackle obstacles to treating brain disorders

A research team led by scientists at the University of Minnesota Medical School and Oregon Health & Science University have outlined the challenges and made suggestions on how to advance research and improve treatments for brain disorders. The review article is published in the January 2008 issue...

Scientists complete genome sequence of fungus responsible for dandruff, skin disorders

Scientists from P&G Beauty announced that they successfully sequenced the complete genome for Malassezia globosa (M. globosa) , a naturally occurring fungus responsible for the onset of dandruff and other skin conditions in humans. Results of the genome sequencing are published in todays online ...

Study reveals possible genetic risk for fetal alcohol disorders

MADISON - New research in primates suggests that infants and children who carry a certain gene variant may be more vulnerable to the ill effects of fetal alcohol exposure. Reported online today (Sept. 21) in Biological Psychiatry, the findings represent the first evidence of a genetic risk for ...

Anxiety disorders surprisingly common yet often untreated

A new study by researchers led by Kurt Kroenke, M.D., of the Indiana University School of Medicine and the Regenstrief Institute, Inc. reports that nearly 20 percent of patients seen by primary care physicians have at least one anxiety disorder. The study outlines the effectiveness of a new screeni...

Men Estimate Men's Risks Of Common Disorders Higher Than Women Do, And Vice Versa

New research from University of Glasgow researchers on lay perceptions about gender differences in health reveals that both men and women believe health risks are higher for their own sex than for the opposite sex. But, it also shows that males think that men are fitter and females think women are ...

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

Late update tonight; my girlfriend is sick and I took care of her. First headline : a newly discovered virus causing respiratory infection. Let's hope its just a coincidence :) A newly discovered virus may be responsible for many respiratory tract illnesses in infants and children, and may be ass...

'Smart' mice teach scientists about learning process, brain disorders

Mice genetically engineered to lack a single enzyme in their brains are more adept at learning than their normal cousins, and are quicker to figure out that their environment has changed, a team led by researchers at UT Southwestern Medical Center has found. The results, appearing today in the...

Bladder cells feel stretch

...critically involved in the sensing mechanism in the bladder, development of chemicals modulating TRPV4 activity may be useful for treatment of bladder disorders such as overactive bladder and pollakiuria." ...

Hormone levels contribute to stress resilience

... additional research is still needed but these findings are a step forward in the quest to help prevent or better treat the symptoms of stress-related disorders that these high-risk individuals experience. ...

La Jolla Institute discovers novel tumor suppressor

...or suppressor that may be important in myeloproliferative diseases and some types of lymphoma and leukemia. Myeloproliferative diseases are a group of disorders characterized by an overproduction of blood cells by the bone marrow and include chronic myeloid leukemia. Lymphoma and leukemia are cancers of the b...

New computer simulation helps explain folding in important cellular protein

...-dimensional structures to work properly. But when for any reason the ribbons fold incorrectly, bad things can happen, and in humans misfolded-protein disorders include Alzheimer's and Parkinson's diseases. Scientists have for the past three decades tried to understand what makes proteins fold into functio...

Maternal, paternal genes' tug-of-war may last well into childhood

...ass., July 28, 2009 -- An analysis of rare genetic disorders in which children lack some genes from one parent ...e for more than one child at a time. Evidence from disorders of genomic imprinting suggests that maternal and p...ic disorders. He found evidence that children with disorders characterized by dominance of some maternal genes ...

Placenta-derived stem cells may help sufferers of lung diseases

...ate characteristics of high plasticity and low immunogenicity. "The potential application of fetal membrane-derived cells as a therapeutic tool for disorders characterized by inflammation and fibrosis is supported in previous studies," says Dr. Ornella Parolini, the study's lead author. "In line with the hy...

Researchers develop 'brain-reading' methods

...nuing research, Hanson and his team plan to develop a system for identifying neural connectivity abnormalities to assist with the study of such mental disorders as attention-deficit hyperactivity and autism and to produce a handbook for many of the new tools used for pattern analysis and the classification of ...

Scientists track impact of DNA damage in the developing brain

...axia (AOA1) and spinocerebellar ataxia with axonal neuropathy (SCAN1). Both disorders are inherited and are characterized by progressive difficulty with walking ... movement. AOA1 is among the most common form of certain inherited movement disorders in Japan and Portugal. McKinnon said those reports sparked new interest in ...

Preimplantation genetic diagnosis may pose neurological risks

...e brains; 36 proteins displayed significant differences between biopsied and control groups, 17 of which are closely associated with neurodegenerative disorders like Alzheimers and Down Syndrome. The authors suggest that the developing nervous system may be sensitive to blastomere biopsy, and that more stu...

Study by NTU professors provides important insight into apoptosis or programmed cell death

...eukemia. When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer, Huntington and Parkinson diseases. While it is established that cells undergo apoptosis when they are damaged by mechanical inju...

Researchers gain insight into mechanism underlying Huntington's

...nderlying Huntington's disease and other neurodegenerative or neuromuscular disorders caused by trinucleotide repeats (or TNRs) in DNA. The research, performe...r systems and become ingrained in an affected gene pool leading to familial disorders has been a longstanding subject of study in my laboratory at the UK Medical...

Alzheimer's disease drug treats traumatic brain injury, report GUMC researchers

... that one therapy could possibly work for both," says the study's lead author, neuroscientist Mark Burns, PhD, an assistant professor at GUMC. Both disorders are associated with build-up of beta amyloid, a toxic brain peptide. This substance is commonly found in the brains of elderly patients who died from ...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

... Mental disorders are a global problem and represent one of the bigg...ental disorders, and in the European Union, mental disorders range as one of the leading causes of disease burd... is that the prevalence of mental and neurological disorders is expected to grow for a variety of reasons: an a...
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(Date:10/18/2014)... patients with undiagnosed, suspected genetic conditions, a certain type ... molecular diagnostic yield than traditional molecular diagnostic methods, according ... study is being released to coincide with the American ... which sequences the protein­coding region of the genome (the ... a cell or organism), has been rapidly applied in ...
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