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Scientists discover how fish evolved to float at different sea depths

Scientists at the University of Liverpool have discovered how fish have evolved over the last 400 million years to stay motionless at different water depths. A research team led by Dr Michael Berenbrink, a Comparative Physiologist at the School of Biological Sciences, has revealed how modern fish, such as pike and cod, have developed a way of floating at certain water levels using a gas-f...

Variation in women's X chromosomes may explain differences among individuals, between sexes

The first comprehensive survey of gene activity in the X chromosomes of women has revealed an unexpected level of variation among individuals, according to new work by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and Pennsylvania State University. The results may have important implications for understanding the differences in traits among women and...

Drug-resistant bacteria on poultry products differ by brand

The presence of drug-resistant, pathogenic bacteria on uncooked poultry products varies by commercial brand and is likely related to antibiotic use in production, according to researchers at the Johns Hopkins Bloomberg School of Public Health. Their study is the first to directly compare bacterial contamination of poultry products sold in U.S. supermarkets from food producers who use antibiotics...

Hirsute Or Hairless? Two Proteins May Spell The Difference

If you're a cat fancier, you're well aware that hair follicles are expendable. The product of a spontaneous mutation that caught a cat breeder's eye, le chat nu, would quickly succumb in the wild—its winter coat consists of little more than a ridge of fur down the midback and tail—and needs special care to thrive as a pet. Hairless animals in the lab, on the other hand, can be very instructive. U...

Different microarray systems more alike than previously thought

A multicenter comparison of equipment that can analyze the expression of thousands of genes at once to create a genetic "fingerprint," suggests these different microarray technologies are more alike than once thought. Published in the May 2005 issue of Nature Methods, the study provides new hope that the mounds of information generated by these systems might actually be comparable, even t...

Study reveals dramatic difference between breast cancers in US and Africa

A study comparing, for the first time, breast cancers from Nigeria, Senegal and North America has found that women of African ancestry are more likely to be diagnosed with a more virulent form of the disease than women of European ancestry. Researchers from the University of Chicago, working with colleagues at the University of Calabar in Nigeria and the University of North Carolina, foun...

Big differences in duplicated DNA distinguish chimp and human genomes

A study comparing the genomes of both humans and chimpanzees has found that much of the genetic difference between the two species came about in events called segmental duplications, in which segments of genetic code are copied many times in the genome. The study appears as a companion article to the draft sequence of the chimpanzee genome published in the Sept. 1 issue of the journal Nature....

Cats' indifference towards sugar explained

Unlike most mammals, cats--both domestic and wild--are indifferent to sweets. A new study in PLoS Genetics explains the molecular mechanism behind their strictly carnivorous behavior. "We took a behavioral question and answered it molecularly," says Joseph Brand, senior author of the study and Associate Director of the Monell Chemical Senses Center. Scattered on mammalian tongues are speci...

Comparison of Cocaine, Methamphetamine ‘Highs?Finds Differences

Don't call them the Dirt Doctors, or Sultans of Soil, they're just clever Lab guys. A team from Los Alamos National Laboratory has a paper in this week's Science Magazine with a new way to count bugs in dirt. Bacteria, that is, in the highly complex world beneath our feet. "Computational Improvements Reveal Great Bacterial Diversity and High Metal Toxicity in Soil," by Jason Gans, Murray W...

Bitter or sweet? The same taste bud can tell the difference

The tongue's ability to differentiate between sweet and bitter tastes may reside in the same taste bud cells, a new study reports....

A slight difference and significant similarities

There is little difference between the composition of the genetically produced potatoes known as fructan potatoes and that of conventionally bred varieties. They only differ in the new substances intentionally incorporated with gene technology. This conclusion has been reached by scientists at the Max Planck Institute of Molecular Plant Physiology and their colleagues from the University of Wales...

Treatments have same target, different responses for lung cancer patients with genetic mutation

The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux), according to a new study published in the August 17 issue of the Some patients with non�small-ce...

Genetics links whale to two different ocean basins

For the first time ever, a genetic study has followed a single humpback whale from one ocean basin to another, adding to traditional notions of the migratory patterns of these majestic marine mammals in the process, according to researchers from the Wildlife Conservation Society (WCS), the American Museum of Natural History (AMNH), and New York University. In the most recent Royal Society's Biolo...

Time and money make a difference in endangered species recovery

Since passage of the Endangered Species Act in 1973, over 1,300 endangered species have been protected in the United States and its territories. In the forthcoming issue of Ecology Letters, Male & Bean assess 14 years of endangered plant and animal status trends and show that the length of time species are protected, and the amount of money spent on their conservation are key variables in exp...

Stem cells bring fast direct improvement, without differentiation, in acute renal failure

Acute renal failure, or ARF, is as serious as it sounds. An estimated 40% of critical care hospital admissions experience ARF. Estimates of their death rate range from 50% to 80%, complicated by the fact that patients with ARF often simultaneously suffer failure of other major organ systems. The most serious form of ARF is caused by ischemia, or loss of blood supply to the kidneys caused b...

Identical twins may have more differences than meet the eye

Identical twins lose some fundamental similarities as they grow older, a new study reports. Researchers report in this week's Proceedings of the National Academy of Sciences that these differences may stem from changes in the epigeno...

Tiny roundworm's telomeres help scientists to tease apart different types of aging

The continual and inevitable shortening of telomeres, the protective "caps" at the end of all 46 human chromosomes, has been linked to aging and physical decline. Once they are gone, so are we. But there are more ways than one to grow old. Researchers at Salk Institute for Biological Studies demonstrate for the first time that the roundworm Caenorhabditis elegans succumbs to the trials of...

Tissue regeneration operates differently than expected

Max Planck researchers in Bad Nauheim discover the mechanism by which adult stem cells are integrated into skeletal or heart muscle tissue. There is disagreement, however, about the mechanism on which repair processes are based. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, in co-operation with colleagues from Martin Luther University in Halle...

Human cerebellum and cortex age in very different ways

Researchers have found that the two primary areas of the human brain appear to age in radically different ways: The cortex used in higher-level thought undergoes more extensive changes with age than the cerebellum, which regulates basic processes such as heartbeat, breathing and balance. Their work, based on an analysis of gene expression in various areas of human and chimpanzee brains, also show...

UCLA scientists discover immune response to HIV differs, even in identical twins

In findings illustrating the difficulty of developing an AIDS vaccine, UCLA AIDS Institute researchers report the immune systems in two HIV-positive identical twins responded to the infection in different ways. ), the findings show that the body's defenses against the v...

Men and women differ in brain use during same tasks

The comedians are right. The science proves it. A man's brain and a woman's brain really do work differently. The study involved volunteers who performed memory...

Attention shoppers: Researchers find neurons that encode the value of different goods

Researchers at Harvard Medical School (HMS) report in the April 23 issue of Nature that they have identified neurons that encode the values that subjects assign to different items. The activity of these neurons might facilitate the process of decision-making that occurs when someone chooses between different goods. "We have long known that different neurons in various parts of the brain re...

Aspirin reduces cardiovascular risks in men and women -- but differently

Aspirin can significantly reduce the risk of cardiovascular events -- a combined endpoint including stroke, heart attack and death due to cardiovascular disease -- in both men and women, according to a new meta-analysis of more than 95,000 patients by a Duke University Medical Center cardiologist. However, the researchers found, the major reasons for the risk reduction differed between the...

Study outlines genetic differences between potential pandemic influenza strains

An analysis of H5N1 influenza samples in Southeast Asia shows not only how the two strains that have caused human disease are related but also that they belong to two different, distinct genetic subgroups. Researchers from the Centers for Disease Control and Prevention report their findings today at the International Conference on Emerging Infectious Diseases. "As the virus continues its...

Forsyth scientists gain greater understanding of how embryos differentiate left from right

Researchers at the Forsyth Institute have discovered a new mechanism responsible for early left/right patterning, the process by which organs locate themselves on the left or right side of the body. The discovery of this novel mechanism, garnered through the study of three different vertebrates (frogs, chickens and zebrafish), marks the first time that a single common mechanism has been identif...

Brain differences could explain why males and females experience pain relief differently

A study conducted by investigators at Georgia State University and the Atlanta-based Center for Behavioral Neuroscience (CBN) reports that anatomical and functional differences in the brain may explain sex differences in the experience of pain and in the effects of certain drugs on pain. The finding, reported in the April 13 issue of the Journal of Comparative Neurology, is the first rep...

Viral 'fitness' explains different resistance patterns to aids drugs

Some HIV medications lead to the development of drug-resistant HIV when patients take as few as two percent of their medications. For other medications, resistance occurs only when patients take most of their pills. These differences appear to be explained by the different levels of viral "fitness" of the drug-resistant HIV, say AIDS researchers in a new study. The research, led by David B...

Most human-chimp differences due to gene regulation ?not genes

The vast differences between humans and chimpanzees are due more to changes in gene regulation than differences in individual genes themselves, researchers from Yale, the University of Chicago, and the Hall Institute in Parkville, Victoria, Australia, argue in the 9 March 2006 issue of the journal The scientists provide powerful new evidence for a 30-year-old theory, propose...

Are dancers genetically different than the rest of us? Yes, says Hebrew University researcher

What makes dancers different than the rest of us? Genetic variants, says a researcher at the Hebrew University of Jerusalem. In a study published in the American journal, Public Library of Science Genetics, Psychology Prof. Richard P. Ebstein and his research associates have shown, through DNA examination, that dancers show consistent differences in two key genes from the general popula...

HIV vaccine takes different tack to boosting immune response

Researchers at Baylor College of Medicine (BCM) in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infection, according to a study published in today's edition of Public Library of Science Medicine. The study in mice boosted the immune response by removing the host's natural immune "brake." By unleashing the immune system's full potentia...

Albatross study shows regional differences in ocean contamination

As long-lived predators at the top of the marine food chain, albatrosses accumulate toxic contaminants such as PCBs, DDT, and mercury in their bodies. A new study has found dramatic differences in contaminant levels between two closely related albatross species that forage in different areas of the North Pacific. Researchers also found that levels of PCBs and DDT have increased in both species ov...

How can identical twins be genetically different?

They sleep together, eat together, and most people find it impossible to tell them apart. Identical twins who grow up together share just about everything, including their genes. But sometimes only one twin will have health problems when genetics predicts both of them should. Scientists at the University of Michigan Medical School are just beginning to understand how two people who are so...

Viral genetic differences are possible key to HIV dementia

The study of 18 HIV-positive subjects shows that HIV in the brain and central nervous system is genetically different from HIV that lives in the blood and peripheral tissues. The study appears in the July 2006 issue of Brain. It was...

African parasite makes component of fat differently from all other organisms

Studying the parasite that causes African sleeping sickness, scientists at Johns Hopkins have discovered a previously unknown way of making fatty acids, a component of fat and the outer layer of all cells. The find unveils more about the biology of this hard-to-kill parasite and could lead to a target for designing new drugs to fight the illness that infects a half-million people and kills 50,000...

Genetic tug of war determines sexual differentiation

Whether or not a fertilized mammalian egg ultimately develops into a male or female is determined by the winner of a tug of war between two different genes encoding signaling proteins and the divergent pathways they control, according to a new study led by Duke University Medical Center cell biologists. In their experiments in mice, the researchers found that two specific genes, Wnt4 and F...

Patients and their doctors have different perceptions about HIV and its treatment

According to results of a nation-wide study published in the latest issue of SAGE Publications' Journal of the International Association of Physicians in AIDS Care (JIAPAC), HIV positive patients and their doctors have very different views about the disease and how it's treated. The study uncovered differences of opinion between patients and physicians about the initiation of treatment, th...

Internal body clock dictates timing of different types of stroke

The internal body clock, or circadian rhythm, seems to influence the timing of different types of stroke, suggests research published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry. These patients' data had been...

UCLA study finds same genes act differently in males and females

UCLA researchers report that thousands of genes behave differently in the same organs of males and females ?something never detected to this degree. Published in the August issue of Genome Research, the study sheds light on why the same disease often strikes males and females differently, and why the genders may respond differently to the same drug. "We previously had no good understandi...

Different strategies underlie the ecology of microbial invasions

Infectious disease can play a key role in mediating the outcome of competition between rival groups, as seen in the effects of disease-bearing conquistadors in the New World--or, on a much smaller ecological scale, the ability of bacteria to spread their viruses to competing bacteria. In a new study, researchers have compared two different general ways in which bacteria compete with one another,...

Proteins may behave differently in natural environments

When in an environment similar to that in which they exist naturally, proteins and multiprotein assemblies may demonstrate actions or dynamics different than those they exhibit when in the static form in which they are most often studied, said researchers at Baylor College of Medicine in a report in the current issue of the journal Structure. In a study using electron cryomicroscopy, Dr....
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