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copy in Biological News

Want to fly? Don't copy the birds and the bees

Since earliest recorded history, and presumably beyond, humans have always wanted to fly. First attempts involved imitation of winged creatures around them, and unfailingly ended in disaster. No workable flying machines have ever looked particularly similar to nature's fliers, and today there is...

Scientists find that squid beak is both hard and soft, a material that engineers want to copy

(Santa Barbara, Calif.) How did nature make the squids beak super hard and sharp allowing it, without harm to its soft body to capture its prey? The question has captivated those interested in creating new materials that mimic biological materials. The results are published in this weeks ...

Clearing jams in copy machinery

Bacteria and humans use a number of tools to direct perhaps the most important function in cells -- the accurate copying of DNA during cell division. New research published this week in Molecular Cell from the laboratory of Rockefeller University's Michael O'Donnell, a Howard Hughes Medical Institu...

Bumblebees copy one another when contending with unfamiliar flowers

Researchers have reported findings that offer a surprising new twist to our understanding of how bumblebees, a vital floral pollinator, select the flowers from which they collect nectar. When faced with unfamiliar plants, foraging bees do not choose flowers entirely alone but instead copy the choic...

Parasites ready to jump

...ew type of cellular defence that acts against DNA sequences present in high copy numbers inside the cell, even if they have not integrated into the genome. ...ow the mechanism is targeted specifically against sequences present in high copy numbers". ...

Jet-propelled imaging for an ultrafast light source

...can outrun radiation damage, always one of the fundamental limitations to imaging in biology. Another quick pulse could be diffracted from another copy of the protein in a different orientation. As the process is repeated, diffractions from different angles give the overlapping views needed for the co...

Nottinghamshire Police First Law Enforcement Agency to Deploy ForensicSoft in United Kingdom

...vironment to ensure a forensically sound preview, exploration and capture of the digital evidence. SAFE employs Microsoft Windows PE (a fully licensed copy is included) and is capable of running your favorite Windows-based forensic tools such as FTK, EnCase, X-Ways, and many more. With SAFE's use of Windo...

Comprehensive look at rare leukemia finds relatively few genetic changes launch disease

... catalog the changes, including single-nucleotide-polymorphism (SNPs) microarrays to chart genome-wide regions of DNA gain or loss, which are known as copy number alterations (CNAs). To identify point mutations, the researchers also performed DNA re-sequencing of 25 genes that are commonly mutated in adul...

ISU researchers find possible treatment for spinal muscular atrophy

...When SMN2 makes enough SMN, it compensates for the mutated or malfunctioning SMN1 gene. All proteins in human bodies are made by copying genes. This copy is called pre-mRNA. Pre-mRNA then becomes mRNA by splicing out certain parts of the sequence that are non-coding, meaning they don't help the functi...

$2 million grant aids study of lung cancer in people who never smoked

...r. The researchers will use lung-cancer cell lines, tumor and lung tissue, and blood specimens to conduct studies in proteomics, gene mutations and copy numbers, microRNAs (ribonucleic acid), methylation, mitochondrial mutations and gene expression. Many of these studies will examine the entire genome....

New research finds possible genetic link to cause of pregnancy loss and disorders

... if a mother's egg cell has a mutation in just one copy of a gene, called Bub1, then she is less likely to...ved to term in the litters of females that had one copy of Bub1," said Venkatachalam. "So this was unusual...ssue to females by mating both a male with one bad copy of the gene with a normal female and a female with...

A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline

...hanced cognitive function, and that this relationship was differentially influenced by the person's APOE genotype: non-E4 carriers and people with one copy of E4 performed better than people with two copies of E4. After adjusting for age, ethnicity, severe chronic medical illness, lean body mass, and educ...

Dogs, humans, put heads together to find cure for brain cancer

...e segments of chromosomes, which makes isolating the specific genes involved extremely difficult. Humans suffering from meningioma frequently lose one copy of almost the entire length of human chromosome 22. This chromosome is made of almost 50 million base pairs of DNA that code for more than 500 genes. ...

Further gene mutations linked to autism risk

...ty of Pennsylvania School of Medicine and The Children's Hospital of Philadelphia (CHOP). The study identified 27 different genetic regions where rare copy number variations missing or extra copies of DNA segments were found in the genes of children with autism spectrum disorders, but not in the healthy...

Genetic finding could lead to targeted therapy for neuroblastoma

...rmed a second validation analysis, pinpointing that a glitch called a "copy number variation" in a single chromosome is associated with neuroblastoma. copy number variation has to do with the gain, loss or duplication of snippets of DNA. "This is part of series of papers that creates the bigger picture...

American Chemical Society's Weekly Presspac -- June 17, 2009

...verall, the fact that chemists are paying closer attention to their choices of reagents and solvents is making process development even greener. For a copy of this story, send an e-mail to m_bernstein@acs.org . ACS pressroom blog The American Chemical Society's Office of Public Affairs (OPA) has ...

DNA template could explain evolutionary shifts

...late switching mechanism involved in some forms of copy number variation. "I think this is going to make people think very hard about copy number variation with respect to genome evolution,...ly discovered method by which the genome generates copy number variation among genes, but it also demonstr...

Researchers observe single protein dimers wavering between two symmetrically opposed structures

...ry of Thomas J. Magliery of Ohio State University, has shown that a protein dimer made up of two identical parts can actually twist itself so that one copy of the protein is turned upside down if its environment is only slightly altered. "It has long been a puzzle as to how proteins, which can theoreti...

Common fish species has 'human' ability to learn

...ow to evade predators. But it is not always a recipe for success to simply copy someone. Animals are often better off being selective about when and who t... at all closely related to humans, yet they have this human ability to only copy when the pay off is better than their own. You might expect this ability i...

Researchers describe 'implausible' chemistry that produces herbicidal compound

...ent synthetic catalysts that can also sever C-C bonds in one step. "Every time we find something new in nature it's an inspiration to see if we can copy that reactivity with a small molecule," van der Donk said. ...

Is this the beginning of the end of plant breeding?

...somes condense into tightly bound structures, and in mitosis these form an X shape in which each half of the X is a chromatid, comprising one complete copy of the chromosome. The double-chromatid chromosomes line up along the centre of the cell. In mitosis, the two chromatids are pulled apartthe X is divi...

New research program BioInterfaces launched

...n-made surfaces, another area of immense technical relevance. "The basic philosophy of the BioInterfaces programme is to learn from nature and then copy it. So, the first stage of our strategy involves a focused, innovative, large-scale analysis to learn more about the natural control mechanisms of cel...

American Chemical Society's Weekly PressPac -- June 3, 2009

...ement officials have to downsize their equipment with one device the size of a fingernail used to find vapors of various explosives. To receive a free copy of this C&EN story, send an e-mail to m_bernstein@acs.org . ACS pressroom blog The American Chemical Society's Office of Public Affairs (OPA) h...

International Serious Adverse Events Consortium announces initial study results in its global research collaboration to identify genetic markers related to drug induced liver injury

...infections. HLA-B is one of a number of highly variable genes responsible for immune function. The study found that individuals carrying at least one copy of HLA-B*5701 were 80-100 times more likely than non-carriers to develop DILI in response to this antibiotic. This risk-associated variant is relativ...

A bad performance is better than no performance at all

...niles had reached the age of 60-70 days and thus had started song development already. Detailed song analysis showed that the juveniles did not simply copy the bad songs of their tutors, but rather developed a version that resembled more the song of normal canaries. "Apparently these birds possess an inna...

American Chemical Society's Weekly PressPac -- May 20, 2009

...earnings rose by only 1.3 percent. No drug companies lost money, but double digit earnings declines at some top firms raised warning flags. For a free copy of this C&EN story about pharma companies' economic problems, send an e-mail to m_bernstein@acs.org . ACS pressroom blog The American Chemical ...

P[acman]-generated fruit fly gene 'library': A new research tool

...y, Drs. Roger Hoskins and Joseph Carlson, played a key role in the design, construction, and annotation of the libraries. "You can insert a single copy of a gene and rescue a mutation, or do a structure/function analysis of the gene," Bellen said. "If you don't know where the gene is expressed, you ca...

Early identification of dementia increasingly difficult

...ed 85-year-olds show that the link between memory problems and dementia is not as clear in this age group. The 85-year-olds' ability to find words, to copy a geometric figure and to take quick decisions were some qualities that were evaluated in a psychiatric assessment. More than 300 individuals particip...

American Chemical Society's Weekly PressPac -- May 13, 2009

...ew years building new water treatment facilities, with help from major international companies with expertise in water purification. To receive a free copy of this must-read C&EN story about China's water needs, send an e-mail to m_bernstein@acs.org . ACS pressroom blog The American Chemical Societ...

Small molecules might block mutant protein production in Huntington's disease

...he earlier in life it appears. A person with the disease carries one normal copy of the gene and one mutated copy in his or her cells. In Huntington's, this CAG repeat occurs in a gene c...

Scientists shed light on inner workings of human embryonic stem cells

... Because there is typically less "wiggle room" in the levels of microRNA compared to mRNA, further studies are needed to quantify more precisely the copy numbers of miR-145 and its targets, to figure out exactly how this layer of control really works, Kosik said. Kosik credits the lion's share of thi...

Cystic fibrosis testing -- next steps

... CFTR gene; cystic fibrosis patients must inherit a mutated gene from each parent. Genetic screening for cystic fibrosis carrier mutations (one copy of a mutated gene) is universally recommended for the reproductive-age population. Current professional guidelines call for screening a panel of 23 c...

Case Western Reserve University engineers hit pay dirt with clay mixture

...d. He says the graduate student replied: "The same thing seven days in a row." While he thought he had made a new discovery, a 1-inch column of copy in an old journal article from the 1940s described a similar substance made with a different kind of clay. Schiraldi knew he was on to something, bu...

New insights into progressive hearing loss

...g data. "We were able quite quickly to show that if the mice carried one copy of the gene variant they suffered progressive hearing loss, if they carried...ls from birth and the cells degenerated from an early age. In mice with one copy of the mutant gene, the effects were less severe, but became worse with age...

Getting down to cancer basics

... team showed that the biology of the mutation fitted their prediction. Cells that lacked a functional UTX gene showed notable slowing of growth when a copy of normal UTX was reintroduced. As well, substantial changes in gene transcription were noted. Genes with the most significant changes in expression w...

MCTP bought Genomatix NextGen Sequencing analysis stations

...analysis solution starting at the raw data from the sequencer, delivering ultra fast mapping, SNP detection, expression profiling and splice analysis. copy number analysis, small RNA analysis and de-novo assembly are following shortly.Results seamlessly feed into second level analysis with the Genomatix G...

Doubling a gene in corn results in giant biomass

...ent approval, but Moose said that this is about as safe a gene as you can get. "It's a gene that's already in the corn all we did was to put an extra copy in that amps it up." ...

New tumor markers determine therapy intensity

... present in three copies (instead of the usual 2 copies) in the genetic material of the brain tumors, the patient's prognosis is poor. If however, one copy of chromosome 6 is missing in the tumor, the patients in the collective observed always survived. The combination of these and other characteristics l...

Boehringer Ingelheim uses Genomatix' Next Generation Sequencing data analysis systems

...hat can be taken into account during the mapping process. Depending on the nature of the experiment, the GMS can provide SNP detection and genotyping, copy number analysis, and small RNA analysis. For ChIPseq data, the GMS delivers clustering and peak finding, and performs automated binding pattern identi...

Doubling a gene in corn results in giant biomass

...ent approval, but Moose said that this is about as safe a gene as you can get. "It's a gene that's already in the corn all we did was to put an extra copy in that amps it up." ...
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