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coli in Biological News

Mystery E. coli genes essential for survival of many species

Scientists have shown that E. coli one of the best known and extensively studied organisms in the world remains an enigma that may hold the key to human diseases, such as cancer. The team, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and based at the Univers...

K-State researchers help Epitopix license the United States' first E. coli O157 vaccine for cattle

Studies by veterinary researchers at Kansas State University, with collaboration from Epitopix LLC, have resulted in the United States' first vaccine against E. coli O157 in beef cattle. "Researchers have done so much to focus on the post-harvest food safety aspect, whether it's E. coli or ...

Transport behavior of E. coli varies depending on manure source

MADISON, WI, MARCH 9, 2009 Escherichia coli is a commonly used indicator organism for detecting the presence of fecal contamination in drinking water supplies. The importance of E. coli as an indicator organism has led to several studies looking at the transport behavior of this important mic...

Escherichia coli bacteria transferring between humans and mountain gorillas

Bwindi, Uganda November 24, 2008 A new study finds that mountain gorillas are at increased risk of acquiring gastrointestinal microbes, such as Escherichia Coli , from humans. The study, published in Conservation Biology , examines the exchange of digestive system bacteria between humans, moun...

Dissecting the genetic components of adaptation of E. coli to the mouse gut

New insights into the evolutionary mechanisms that facilitate the remarkably fast adaptation of intestinal bacteria within their natural environment are provided in the January issue of PLoS Genetics by researchers from INSERM and INRA at University Paris Descartes. Using germ-free mice a simp...

Understanding, combating foodborne pathogens E. coli 0157 and salmonella

MANHATTAN, KAN. -- Understanding the ecology of two dangerous foodborne pathogens and devising ways to combat them is a big job. That's why Kansas State University has a team of seven researchers and six collaborators taking on E. coli 0157 and salmonella. "It's becoming more and more difficult...

Plant Min protein sits tight and rescues E. coli

This release is available in Chinese . A protein vital for correct chloroplast division in plants is able to take on a similar role in bacterial cells, according to research published today in the open access j...

Sesame seed extract and konjac gum may help ward off Salmonella and E. coli

A new study in SCI's Journal of the Science of Food and Agriculture shows that konjac gum and sesame seed extract may offer protection against different strains of E. coli and Salmonella bacteria. The study by Dr Petra Becker et al from Wageningen University and Research Centre, the Netherlan...

Poultry workers at increased risk of carrying antibiotic-resistant E. coli

Poultry workers in the United States are 32 times more likely to carry E. coli bacteria resistant to the commonly used antibiotic, gentamicin, than others outside the poultry industry, according to a recent study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health. Whil...

K-State researchers findings on E. coli

MANHATTAN, KAN. -- Ethanol plants and livestock producers have created a symbiotic relationship. Cattle producers feed their livestock distiller's grains, a byproduct of the ethanol distilling process, giving ethanol producers have an added source of income. But recent research at Kansas State ...

Yale scientists use nanotechnology to fight E. coli

New Haven, Conn. Single-walled carbon nanotubes (SWCNTs) can kill bacteria like the common pathogen E. coli by severely damaging their cell walls, according to a recent report from Yale researchers in the American Chemical Society (ACS) journal Langmuir. We began the study out of concerns for ...

E. coli bacteria migrating between humans, chimps in Ugandan park

Scientists from the University of Illinois at Champaign-Urbana have found that people employed in chimpanzee-focused research and tourism in a park in western Uganda are exchanging gastrointestinal bacteria ?specifically Escherichia coli ?with local chimpanzee populations. And some of the E. coli s...

Technology exists to keep E. coli out of food

In a groundbreaking study at the University of Minnesota, Extension food scientist Joellen Feirtag has been experimenting since April with a water-based electrochemical activation system that disinfects, cleans food and wipes out E. coli. While electrolyzed water systems are not new, this system...

New study reveals structure of E. coli multidrug transporter protein

This new study could potentially help researchers find new ways to avoid the problem of multidrug resistance and enhance the potency of existing drug compounds. The study is being published in ScienceXpress, an advance online edition of the journal Science, on May 5. "The development of antib...

Basic work on E. coli identifies two new keys to regulation of bacterial gene expression

The cellular process of transcription, in which the enzyme RNA polymerase constructs chains of RNA from information contained in DNA, depends upon previously underappreciated sections of both the DNA promoter region and RNA polymerase, according to work done with the bacterium E. coli and published...

MBL leads effort to update E. coli genome

E.coli is one of the most important model organisms for molecular science today and is arguably the single organism about which the most is known. The genes of higher-level plants and animals, even humans, are often understood by their similarity to E. coli genes. As such, the accuracy and complet...

How E. coli bacterium generates simplicity from complexity

The ubiquitous and usually harmless E. coli bacterium, which has one-seventh the number of genes as a human, has more than 1,000 of them involved in metabolism and metabolic regulation. Activation of random combinations of these genes would theoretically be capable of generating a huge variety of i...

Vaccine blocks malaria transmission in lab experiments

...th's W. Harry Feinstone Department of Molecular Microbiology and Immunology. For the study, the research team expressed full-length Pfs48/45 in E. coli bacteria to produce the vaccine. Previous attempts to fully express the protein had not been successful. The vaccine was first given to mice in the la...

Munich researchers discover new target for tailored antibiotics

... crystal structure opened the door to a detailed examination of the reaction mechanism using computer simulation and mutagen experiments, in which E. coli bacteria are coerced into synthesizing defective IspH enzymes. Thus, the X-ray structure, kinetic measurements, and mutagenic analyses ultimately con...

Spontaneous assembly

... Public Library of Science entitled: "Self-Organization of the Escherichia coli Chemotaxis Network Imaged with Super-Resolution Light Microscopy." Co-autho... to be found within prokaryotic cells, such as rod-shaped bacteria like E. coli . "It has remained somewhat mysterious how bacteria are able to organize...

Researchers observe single protein dimers wavering between two symmetrically opposed structures

...rol disease, Deniz notes. Head or Tail? In the new study, the researchers examined a protein known as Rop (repressor of primer), expressed in E. coli bacteria, which binds to RNA to regulate the number of copies of plasmid genes produced within the bacteria. This small "homodimer" is made up of two ...

Tips from the journals of the American Society for Microbiology

...with L5 were highly effective in preventing death when inoculated with Staphylococcus aureus Smith, Enterococcus faecalis SR1004, and Escherichia coli EC14. More specifically, normal injections of L5 prior to infection greatly reduced rates of death and intra-abdominal administration of L5 increase...

A tiny frozen microbe may hold clues to extraterrestrial life

...h colonies of very small purple-brown bacteria were seen. H. glaciei is small even by bacterial standards it is 10 to 50 times smaller than E. coli . Its small size probably helped it to survive in the liquid veins among ice crystals and the thin liquid film on their surfaces. Small cell size is c...

Researchers engineer metabolic pathway in mice to prevent diet-induced obesity

... metabolism in mammals, Liao's team cloned bacteria genes from Escherichia coli that would enable the shunt, then introduced the cloned E. coli genes into the mitochondria of liver cells in mice; mitochondria are where...

Boston University biomedical engineers teach bacteria to count

...t the organism is no longer in the environment or your body." Collins' team designed two separate synthetic gene networks not found naturally in E. coli bacteria. Each uses a different method to make the bacteria count. The first, the Riboregulated Transcriptional Cascade (RTC) synthetic gene networ...

The evolution of gene regulation

...activity of cells to internal and external conditions even in microorganisms. It is known, for example, that the intestinal bacterium Escherichia coli in the digestive tract of young mammals can break down lactose, the sugar abundant in mother's milk. To do this, the bacterium produces the enzyme lac...

NEWSLETTER: Antibody Fragment Production Breakthrough with 2nd Generation EBA

...h; Richter-Helm BioLogics GmbH & Co. KG announces today a technological breakthrough in the field of purification of antibody fragments from an E. coli expression system. Richter-Helm BioLogics has finalized the downstream process for Phase III clinical trial material using 2nd Generation Expanded B...

Genetic switch potential key to new class of antibiotics

...senior author. "Among the bacteria now known to contain riboswitches are E. coli and streptococcus, as well as the bacteria behind forms of anthrax, gonorrh...causing ability. Previous experiments showed that bacteria like Escherichia coli (a main cause of food poisoning) and Shigella flexneri (a main cause of dys...

Research could lead to new non-antibiotic drugs to counter hospital infections

... P. aeruginosa to become lethal. To test this theory, they let worms (Caenorhabditis elegans) feed on "lawns" of P. aeruginosa and Escherichia coli grown in both low-phosphate and high-phosphate media. Only the worms that ate P. aeruginosa with low levels of phosphate died. The researchers dubbe...

UGA licenses invention that kills food-borne pathogens in minutes

...U.S. The new technology, invented by scientists from the University of Georgia Center for Food Safety, can kill significant numbers of dangerous E. coli and salmonella in less than one minute, but it is recommended that the wash be applied from one to five minutes. The technology can be used as a food ...

Tips from the American Journal of Pathology

...ay cause disease. Some bacteria, such as Escheria coli ( E. coli ) or Citrobacter rodentium ( C. rodentium ), can...n produced by gram negative bacteria including E. coli and C. rodentium , has been associated with bact...

When intestinal bacteria go surfing

... The bacterium Escherichia coli is part of the healthy human intestinal flora. However, E. coli also has pathogenic relatives that trigger diarrhea illnesses: enterohemor...

Synthetic biology can help extend anti-malaria drug effectiveness

... By transplanting genes from yeast and from the sweet wormwood tree into E. coli bacteria and then bypassing the E. coli's metabolic pathway and engineering...e-synthesis and other techniques to improve the yield of amorphadiene in E. coli by a million fold from where started," Keasling said. In 2004, Keasling ...

Protein structure determined in living cells

...ure of a protein within the bacterium Escherichia coli . "We have reached an important goal of molecular ...binding protein into the model system Escherichia coli , where the protein was in high concentration. ...ee-dimensional structure of the protein within E. coli cells using software that was developed in their ...

Milestone achieved toward production of malaria treatment using synthetic biology and fermentation

...he antimalarial agent artemisinin, in Escherichia coli " appears in PLoS ONE , an open-access journal fr...e production of 25 g/L of amorphadiene through E. coli fermentations. The production of amorphadiene in E. coli was first described in 2003 but the amount produc...

Special issue of BMC Microbiology spotlights standardized language for describing microbes

...bacterial organisms is shown by taking a close-up look at the plant pathogen Pseudomonas syringae pv tomato DC3000 and the animal pathogen Escherichia coli strains. Many plant pathogens that draw their nutrition from living tissue have evolved sophisticated ways to interfere with programmed cell death,...

Tailor-made recombinant proteins in mammals

...ng insulin for diabetes, can be made in bacterial systems like Escherichia coli , but most protein pharmaceuticals must be expressed in cultured mammalian ...or pinpointing chemical reactions to sites on recombinant proteins from E. coli , Bertozzi and her colleagues showed that it works equally well in the most...

Scripps scientists create first crystal structure of an intermediate particle in virus assembly

...rocesses involved. The scientists built the viral shells in a test tube. Genes that encode the 420 proteins that make up the coat were expressed in e coli bacteria, the normal host of the virus. These proteins spontaneously assemble and form the immature particles. In the presence of viral DNA and the en...

Long-sought protein structure may help reveal how 'gene switch' works

...called X-ray diffraction. However, the structure of the inactive ("off") E. coli CRP eluded them as attempts to crystallize it repeatedly failed. With only ...cobacterium tuberculosis [the pathogen that causes tuberculosis] for the E. coli protein. The team's initial successobtaining crystals of CRP in the "o...

Bacteria are models of efficiency

... and Tadmor found that their model was able to accurately predict how an E. coli would change its production strategy to maximize efficiency following disru...osome production. It turns out that that's exactly the number an average E. coli cell has. Bacteria having five or nine get a much lower efficiency rating....
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