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NIH announces new program to develop therapeutics for rare and neglected diseases

...rapy in patients. Clinical trials go through several stages that take several years to determine the safety and efficacy of a new drug. FDA will only approve a drug for general use after it passes these trials. This is also an expensive process, but the failure rate is lower at this stage. "NIH tradition...

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

...as that the number of siRNAs we would have to test in order to have impact on the disease would be too large, and as a consequence the FDA would never approve any trial," he continued. By adding an siRNA against one of two other common SNPs, Zamore says gene silencing could be effective in 75 percent of p...

When fish farms are built along the coast, where does the waste go?

...ccurately predicting where the unhealthy effluent from fish pens will end up, and should probably not be used by state or federal regulators when they approve locations for fish farms. Existing software is typically derived from models that attempt to describe the drift of effluent from sewage outfall pipe...

New standard for popular stevia-based sweetener to assure product's quality

...008, for 90 days. After this comment period, USP's Food Ingredients Expert Committee, which comprises a group of independent, scientific experts, will approve the final monograph to be included in the 2009 FCC supplement. The FCC monograph for Rebaudioside A will contain specifications related to the ing...

Ecological Society of America criticizes administration's overhaul of the Endangered Species Act

... provide little incentive for agencies to assess their work as rigorously as an unbiased reviewer. "What if we allowed pharmaceutical companies to approve and distribute drugs without consulting the Food and Drug Administration?" she asks. "The result would spell potential disaster for humans. In this ca...

UTSA receives $822,000 from Kleberg Foundation to enhance scientific research

...tribute to the Klebergs legacy of philanthropy, said Romo. So, several months ago, we asked the Board of Regents of the University of Texas System to approve the naming of one of our more popular student gathering places outside the new Biotechnology, Sciences and Engineering Building as the Kleberg Commons...

DOE publishes update of plan: 'Facilities for the Future of Science: A 20-Year Outlook'

...s to proceed. Then came a revised proposal in 2004, very positive reviews by scientific leaders in the field worldwide, and DOE decisions in 2005 to approve its mission need and in 2007 to locate the machine at Brookhaven National Laboratory and initiate project engineering and design in fiscal year 2007. ...

Majority of Americans want local action on global warming, says poll

...ing electric utilities to produce at least 20 percent of their electricity from wind, solar and other renewable energy sources. 68 percent would approve changing their city or town zoning rules to decrease suburban sprawl and concentrate new development near the town center. 65 percent would supp...

Americans remain pessimistic about the environment, Stanford-AP survey finds

... percent in 2006). Approval of U.S. businesses' handling of the environment also stayed constant, at 22 percent (21 percent in 2006). ''Republicans approve of U.S. businesses significantly more than do Democrats-31 percent versus 19 percent,'' Krosnick noted. ''This was true in 2006 as well-32 percent ver...

Georgia Tech/Emory Center to study origin of life

...ive research and innovation in the field. The Georgia Tech-Emory grant is Phase I funding; at the end of Phase I in three years, the NSF may choose to approve The Origins Project for Phase II funding, which will provide up to $15 million over five years. The center's research will seek to understand what ...

Growth hormone is not the anti-aging bullet for healthy adults

...ormone. "Think about all the scientific claims made on anti-aging Web sites based on this small population of patients. The FDA typically doesn't approve a drug until it's been tested in thousands of patients. "In our review, we found that growth hormone increased lean body mass or muscle mass by s...

Ten years later, Dolly is still making headlines

... Center to discuss the various regulatory, scientific and ethical issues surrounding generic biopharmaceuticals, as well as: Why is the FDA slow to approve biogenerics? What are the risks of a biogeneric drug, like a human growth hormone, being used for the off-label purpose of anti-aging? With $20B of ...

Cincinnati surgeons report new treatment for often-fatal injury

...later. Surgeons must repair the damaged aorta quickly before it does rupture, killing the patient. The Food and Drug Administration has yet to approve a device for treatment of this type of injury, says Dr. Giglia, and custom-made devices are usually large and difficult to use in an emergency setting...

Computer scientist sorts out confusable drug names

... went into cardiac arrest. A few years ago, the FDA turned to Project Performance Corporation (PPC), a U.S. software company, to ensure they don't approve the names of new drugs that may easily be confused with any one of the more than 4,400 drugs that have already been approved. PPC looked at the pr...

Center releases new public survey on stem cells

...rcent) accord embryos some intermediate moral status. A third of those who believe an embryo in a Petri dish has maximum moral status nonetheless approve of ESC research. Similarly, a third support ESC research policies more permissive than the current policy and which involve funding for research usin...

Researchers find Amchitka seafood safe for now

...F workshop suggested a technical path forward, the State and the Department signed a Letter of Intent that assigned the four party team (see above) to approve a plan for the needed research and to help assure the independence of the CRESP study. 18 months after CRESP was given partial funding and the actual ...

Genetically modified maize not found in southern Mexico

...genic seeds may have declined if farmers became aware of the issue and took extra precautions with their seed stocks." The Mexican government might approve the cultivation of GM maize at some point in the future ?meanwhile, transgenic seeds can easily enter Mexico from the United States, and more cases of...

Can two killers make a cure?

... Regulators in the US could soon be asked to approve a human trial of gene therapy for cystic fibrosis that uses a hybrid of the HIV and Ebola viruses. Tests on monkeys show the hybrid virus delivers gen...

Canada approves marijuana-based pain spray

...tive treatment for the symptomatic relief of neuropathic pain in adults with multiple sclerosis (MS). Canada becomes the first country in the world to approve Sativex, a novel prescription pharmaceutical product derived from components of the cannabis plant shown to have therapeutic properties. Sativex is ad...

Medical whistleblowers speak out

...ies through the Prescription Drug User Fee Act "to approve new drugs and approve them more quickly." A senior official at the FDA, ... Another lesson, says Lenzer, is that "the race to approve new drugs without proper safety testing may be com...
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