Vision

Needling Chromosomes Reveals Cell Division Secret

By impaling individual chromosomes with glassneedles one thousandth the diameter of a human hair, a Duke Universitygraduate student has tested their "stickiness" to one another duringcell division. Her uncanny surgical skills have added a piece to thelarge and intricate puzzle of how one cell divides into two -- aprocess fundamental to all organisms.In the Dec. 14, 2004, issue of Current Bi...

Devising Nano Vision for an Optical Microscope

Contrary to conventional wisdom, technology’s advance into the vanishingly small realm of molecules and atoms may not be out of sight for the venerable optical microscope, after all. In fact, research at the National Institute of Standards and Technology (NIST) suggests that a hybrid version of the optical microscope might be able to image and measure features smaller than 10 nanometers—a tiny fr...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

Ophthalmologists at Rush University Medical Center implanted Artificial Silicon Retina (ASR) microchips in the eyes of five patients to treat vision loss caused by retinitis pigmentosa (RP). The implant is a silicon microchip 2mm in diameter and one-thousandth of an inch thick, less than the thickness of a human hair. Four patients had surgery Tuesday, January 25. The fifth patient is sch...

Key mechanism in genetic inheritance during cell division identified

A key mechanism in the passing of genetic material from a parent cell to daughter cells appears to have been identified by a team of Berkeley researchers. Their study may explain how a complex of proteins, called kinetochores, can recognize and stay attached to microtubules, hollow fibers in the walls of biological cells that are responsible for the faithful segregation of chromosomes during cell...

Migratory songbirds have a specialized night-vision brain area

Neurobiologists have discovered a specialized night-vision brain area in night-migratory songbirds. They believe the area might enable the birds to navigate by the stars, and to visually detect the earth's magnetic field through photoreceptor molecules, whose light-sensitivity is modulated by the field. The researchers published their findings May 23, 2005, in the early online edition of t...

Pair of cancer genes found to drive both cell migration and division

Johns Hopkins researchers have found that two genes already known to control cell movement are also needed for proper cell division. They report their findings in the April issue of Developmental Cell. The researchers discovered that the two genes are required for a dividing cell's halves to separate, raising the possibility that interfering with them could be helpful in stopping the uncon...

Hunt for human genes involved in cell division under way

A systematic search through human genes has begun at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Working within the MitoCheck consortium that includes 10 other institutes throughout Europe, the EMBL scientists will silence all human genes, one-by-one, to find those involved in cell division (mitosis) and to answer fundamental questions of how cell division is regulate...

Sugar helps control cell division

Johns Hopkins scientists have discovered that a deceptively simple sugar is in fact a critical regulator of cells' natural life cycle. The discovery reveals that, when disturbed, this process could contribute to cancer or other diseases by failing to properly control the steps and timing of cell division, the researchers say. The findings are described in the Sept. 23 issue of the Journal...

Multiple genes permit closely related fish species to mix and match their color vision

Vision, like other biological attributes, is shaped by evolution through environmental pressures and demands, and even closely-related species that are in other ways very similar might respond to their particular environments by interpreting the visual world slightly differently, using photoreceptors that are attuned to particular wavelengths of light. By studying a special group of closely-relat...

'Computer-chemistry' yields new insight into a puzzle of cell division

Duke University biochemists aided by Duke computer scientists and computational chemists have identified the likely way two key enzymes dock in an intricate three-dimensional puzzle-fit to regulate cell division. Solving the docking puzzle could lead to anticancer drugs to block the runaway cell division behind some cancers, said the researchers. Significantly, their insights arose not ju...

Genes involved in cell growth and cell division identified

A recent study shows that hundreds of genes contribute to cell growth and cell division. For the first time these genes, many of which are potential contributors to cancer, have been mapped in a single systematic study. The group led by Professor Jussi Taipale (University of Helsinki and National Public Health Institute of Finland) has identified genes contributing to cell growth and cell...

Researchers solve mystery of how nuclear pores duplicate before cell division

Researchers have long wondered how nuclear pores ?the all-important channels that control the flow of information in and out of a cell's nucleus ?double in number to prepare for the split to come when a cell divides. Now, for the first time, scientists at the Salk Institute for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into the nucl...

Behavioral studies show UV contributes to marsupial color vision

Work reported this week provides new evidence that marsupials, like primates, have functional color vision based on three different types of color photoreceptor cones--but unlike primates, a component of marsupial color vision includes sensitivity to ultraviolet wavelengths. In the study, researchers employed behavioral tests to show that at least one type of marsupial uses its detection...

'Word-vision' brain area confirmed

Humans have an uncanny ability to skim through text, instantly recognizing words by their shape--even though writing developed only about 6000 years ago--long after humans evolved. Thus, neuroscientists have hotly debated whether an area of the cortex called the Visual Word Form Area (VWFA) is truly a specific and necessary area for recognizing words. Functional MRI scans have shown that...

Lizard 'third eye' sheds light on evolution of color vision

Published in the March 17 issue of Science, their lizard study describes how the "side-blotched" lizard's so-called third, or parietal, eye, distinguishes two different colors, blue and green, possibly to tell the time of day. Specialized nerve cells in that eye, which looks more like a spot on the lizard's forehead, use two types of molecular signals to sense light: those found only in simpler...

Rewind, please: Nature paper shows that cell division is reversible

Gary J. Gorbsky, Ph.D., a scientist with the Oklahoma Medical Research Foundation, has found a way to reverse the process of cell division. "No one has gotten the cell cycle to go...

Scientists discover why cornea is transparent and free of blood vessels, allowing vision

Scientists at the Harvard Department of Ophthalmology's Schepens Eye Research Institute and Massachusetts Eye and Ear Infirmary (MEEI) are the first to learn why the cornea, the clear window of the eye, is free of blood vessels--a unique phenomenon that makes vision possible. The key, say the researchers, is the unexpected presence of large amounts of the protein VEGFR-3 (vascular endothelial gro...

Bone marrow may restore cells lost in vision diseases

University of Florida scientists conducting experiments with mice have found evidence that the body naturally replenishes small amounts of cells in the eye essential for healthy vision. The finding may shatter the belief that a cell layer vital for eyesight called the retinal pigment epithelium, or RPE, is a nonrenewable resource, say researchers writing in a recent issue of Investigative...

Virginia Tech's System X supercomputer provides super tool for simulation of cell division

Virginia Tech researchers in computer science and biology have used the university's supercomputer, System X, to create models and algorithms that make it possible to simulate the cell cycle -- the processes leading to cell division. They have demonstrated that the new mathematical models and numerical algorithms provide powerful tools for studying the complex processes going on inside living cel...

Stem cell therapy shows promise for rescuing deteriorating vision

For the millions of Americans whose vision is slowly ebbing due to degenerative diseases of the eye, the lowly neural progenitor cell may be riding to the rescue. In a study in rats, neural progenitor cells derived from human fetal stem cells have been shown to protect the vision of animals with degenerative eye disease similar to the kinds of diseases that afflict humans. The new study ap...

Biologically inspired sensors can augment sonar, vision system in submarines

To find prey and avoid being preyed upon, fish rely on a row of specialized sensory organs along the sides of their bodies, called the lateral line. Now, a research team led by Chang Liu at the University of Illinois at Urbana-Champaign has built an artificial lateral line that can provide the same functions in underwater vehicles. "Our development of an artificial lateral line is aimed at...

Making mice with enhanced color vision

Researchers at the Johns Hopkins School of Medicine and their colleagues have found that mice simply expressing a human light receptor in addition to their own can acquire new color vision, a sign that the brain can adapt far more rapidly to new sensory information than anticipated. This work, appearing March 23 in Science, also suggests that when the first ancestral primate inherited a n...

Newborn brains grow vision and movement regions first

The regions of the brain that control vision and other sensory information grow dramatically in the first few months following birth, while the area that controls abstract thought experiences very little growth during the same period, University of North Carolina at Chapel Hill researchers have found. The researchers discovered that the back regions of the brain, which control vision and s...

New study challenges 'critical period' in childhood vision development

Understanding how the human brain learns to perceive objects is one of the ultimate challenges in neuroscience. In 2003, Pawan Sinha, a professor at the Massachusetts Institute of Technology, launched an initiative with the hopes of shedding some light on the acquisition of visual skills. The goal of his "Project Prakash" is to find, treat, and study congenitally blind children in India. A uniq...

Action video games sharpen vision 20 percent

Video games that contain high levels of action, such as Unreal Tournament, can actually improve your vision. Researchers at the University of Rochester have shown that people who played action video games for a few hours a day over the course of a month improved by about 20 percent in their ability to identify letters presented in clutter—a visual acuity test similar to ones used in regul...