More than half of Texas physicians do not always recommend HPV vaccine to girls

PHILADELPHIA - The Advisory Committee on Immunization Practices recommends the human papillomavirus vaccination for all 11- and 12-year-old girls, but results of a recent survey showed that more than half of Texas physicians do not follow these recommendations. The survey was published in Can...

First genetically-engineered malaria vaccine to enter human trials

Walter and Eliza Hall Institute scientists have created a weakened strain of the malaria parasite that will be used as a live vaccine against the disease. The vaccine, developed in collaboration with researchers from the US, Japan and Canada, will be trialled in humans from early next year. Mala...

Penn-Wistar team gains insight into HIV vaccine failure

PHILADELPHIA (July 20, 2009) A team of researchers from The Wistar Institute and the University of Pennsylvania reports new evidence refuting a popular hypothesis about the highly publicized failure in 2007 of the Merck STEP HIV vaccine study that cast doubt on the feasibility of HIV-1 vaccines....

LSUHSC's Kolls awarded $1.8 million to improve vaccine strategies for P. carinii pneumonia

New Orleans, LA Jay K. Kolls, MD, Professor and Chairman of Genetics at LSU Health Sciences Center New Orleans School of Medicine, has been awarded $1.8 million over five years by the National Heart, Lung and Blood Institute of the National Institutes of Health to study whether antibodies that re...

UTSA infectious disease researchers advancing vaccine against Valley fever

San Antonio Medical mycologists in The South Texas Center for Emerging Infectious Diseases (STCEID) and the Department of Biology at The University of Texas at San Antonio (UTSA) have significantly advanced the fight against San Joaquin Valley Fever, a respiratory infection of humans, commonly ca...

Targeting children effective use of limited supplies of flu vaccine and could help control flu spread

Targeting children may be an effective use of limited supplies of flu vaccine, according to research at the University of Warwick funded by the Wellcome Trust and the EU. The study suggests that, used to support other control measures, this could help control the spread of pandemics such as the cu...

Preventing ear infections in the future: Delivering vaccine through the skin

An experimental vaccine applied the surface of the skin appears to protect against certain types of ear infections. Scientists from the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, report their findings today at the 109th General Meeting of the American Society for Micr...

Novel vaccine approach offers hope in fight against HIV

A research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers. By using gene transfer technology that produces molecules that block infection, the scientists prote...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

CHICAGO - An experimental vaccine that triggers the patient's immune system to identify and attack specific tumor cells is showing new promise for the treatment of early lung cancer. Thoracic surgeons at Rush University Medical Center are researching the vaccine called MAGE-A3 Antigen-Specific Ca...

HPV vaccine may prevent preterm births

Chronic human papilloma virus (HPV)-infections can lead to cellular changes in the cervix that can be a pre-stage to cervical cancer. Surgical treatment of these pre-stages gives an increased risk of preterm birth in subsequent pregnancies. As the HPV-vaccine can prevent pre-stages of cervical can...

K-State researchers help Epitopix license the United States' first E. coli O157 vaccine for cattle

Studies by veterinary researchers at Kansas State University, with collaboration from Epitopix LLC, have resulted in the United States' first vaccine against E. coli O157 in beef cattle. "Researchers have done so much to focus on the post-harvest food safety aspect, whether it's E. coli or ...

New vaccine developed for preventing 'uncommon cold' virus

FAIRFAX, Va. Common colds typically cause a week of sneezing, aches and pains and then fade away leaving only a sore nose and a few used sick days behind. But what if that cold turned out to be something more? Human adenovirus type-3 is known as the "uncommon cold" because the infection's symp...

Fractional dose of scarce meningitis vaccine may be effective in outbreak control

One fifth of the standard dose of a commonly used meningitis vaccine may be as effective as using the full dose. This new finding should allow scarce vaccine resources to be stretched further, especially during epidemics in Africa. In a study initiated by the Norwegian Institute of Public Healt...

Flu shot protects kids -- even during years with a bad vaccine match

Children who receive all recommended flu vaccine appear to be less likely to catch the respiratory virus that the CDC estimates hospitalizes 20,000 children every year. This is according to new research published in Pediatrics by the University of Rochester Medical Center. The study looked at...

UT Southwestern researcher awarded Gates Foundation grant for novel vaccine development

DALLAS Oct. 22, 2008 The Bill and Melinda Gates Foundation announced today that it has awarded a UT Southwestern Medical Center scientist a grant to pursue innovative vaccine research. The $100,000 grant to Dr. Ellen Vitetta, director of the Cancer Immunobiology Center at UT Southwestern, is ...

Research identifies type of vaccine that holds promise in protecting against TB

ST. LOUIS -- Researchers are one step closer to finding a vaccine that better protects against tuberculosis. An investigational vaccine for TB tested at Saint Louis University appears likely to offer significantly better protection against the potentially fatal disease than the one in current use....

Bird flu vaccine protects people and pets

A single vaccine could be used to protect chickens, cats and humans against deadly flu pandemics, according to an article published in the November issue of the Journal of General Virology . The vaccine protects birds and mammals against different flu strains and can even be given to birds while ...

RNA molecules, delivery system improve vaccine responses, effectiveness

AUSTIN, Texas A novel delivery system that could lead to more efficient and more disease-specific vaccines against infectious diseases has been developed by biomedical engineers at The University of Texas at Austin. The findings use specific ribonucleic acid (RNA) molecules to significantly bo...

Nano vaccine for hepatitis B shows promise for third world

ANN ARBOR, Mich. Chronic hepatitis B infects 400 million people worldwide, many of them children. Even with three effective vaccines available, hepatitis B remains a stubborn, unrelenting health problem, especially in Africa and other developing areas. The disease and its complications cause an e...

UCF professor develops vaccine to protect against black plague bioterror attack

A University of Central Florida researcher may have found a defense against the Black Plague, a disease that wiped out a third of Europe's population in the Middle Ages and which government agencies perceive as a terrorist threat today. UCF Professor Henry Daniell and his team have developed a...

Footrot vaccine closer than ever

Monash University scientists have started clinical trials to find a successful vaccine against footrot in sheep. The trials have been made possible with funding of $663,000 from Australian Wool Innovation (AWI) The trials over three years are taking place at Monash University's Australian R...

LIAI researchers discover new cellular mechanism that will significantly advance vaccine development

SAN DIEGO (June 16, 2008) La Jolla Institute for Allergy & Immunology (LIAI) scientists have discovered one for the textbooks. Their finding, reported Friday in the scientific journal Immunity , illuminates a new, previously unknown mechanism in how the body fights a virus. The finding runs co...

A protein sequence associated with Huntington’s disease may become life-saving vaccine component

On June 10, 2008 the scientific journal " Vaccine " published a paper by the Massachusetts based biotech company Cure Lab, Inc., demonstrating that a protein sequence important in neurodegenerative Huntington's disease can be safely used as a new generation of vaccine adjuvants. The major comp...

New technology for boosting vaccine efficiency

One of the most pressing biomedical issues is the development of techniques that increase the efficiency of vaccines. In a paper published on April 24, 2008 in the journal Vaccine, a Massachusettss biotechnology company, Cure Lab, Inc. has proposed a new technology for anti-viral vaccination. This...

New vaccine may give long-term defense against deadly bird flu and its variant forms

WEST LAFAYETTE, Ind. - A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in m...

HIV isolate from Kenya provides clues for vaccine design

Two simple changes in its outer envelope protein could render the AIDS virus vulnerable to attack by the immune system, according to research from Kenya and the Fred Hutchinson Cancer Research Center published in PLoS Medicine. The results could provide important clues for designing an effectiv...

CWRU School of Medicine has evidence vaccine against malaria will reduce disease

CLEVELAND December 20, 2007 Researchers at the Case Western Reserve University School of Medicines Center for Global Health & Diseases published data potentially impacting the three billion people exposed to malaria every year. Brian T. Grimberg, Ph.D., Peter A. Zimmerman, Ph. D., and Christophe...

Influenza vaccine causes weaker immune response for children of rural Gabon than in semi-urban areas

Researchers have found that vaccination against influenza strains seem to be more effective in a semi-urban population than in a rural population of schoolchildren in Gabon, Africa, according to an article in the Journal of Infectious Diseases, published by the University of Chicago Press in partn...

Flu vaccine in painless skin patches under development at Emory, Georgia Tech with NIH grants

Flu vaccine delivered through painless microneedles in patches applied to the skin could soon be an alternative to delivery through hypodermic needles, according to researchers at Emory University and the Georgia Institute of Technology. Using new grants from the National Institutes of Health (NIH...

New nanoparticle vaccine is more effective but less expensive

Good news for public health: Bioengineering researchers from the EPFL in Lausanne, Switzerland, have developed and patented a nanoparticle that can deliver vaccines more effectively, with fewer side effects, and at a fraction of the cost of current vaccine technologies. Described in an article...

Study by Pittsburgh researchers identifies possible vaccine target for chlamydia

Scientists at Childrens Hospital of Pittsburgh of UPMC have identified a potential target for the development of a vaccine against Chlamydia trachomatis, the most prevalent sexually transmitted bacterial infection in the world. The researchers, led by Toni Darville, MD, chief of the Division of...

UTSA, Health Science Center collaborate with Merck & Co. to develop chlamydia vaccine

San Antonio TX -- The University of Texas at San Antonio (UTSA) and The University of Texas Health Science Center at San Antonio (Health Science Center) today announced an exclusive license and sponsored research agreement with Merck & Co., Inc., to develop a vaccine for chlamydia, targeting the c...

A natural approach for HIV vaccine

For 25 years, researchers have tried and failed to develop an HIV vaccine, primarily by focusing on a small number of engineered "super antibodies" to fend off the virus before it takes hold. So far, these magic bullet antibodies have proved impossible to produce in people. Now, in research to be...

African-Americans aware and accepting, but often do not receive, the HPV vaccine

CAREFREE, A.Z. - Although only 25 percent of eligible African-American adolescents have received the HPV vaccine, a new survey presented at the American Association for Cancer Research conference on the Science of Cancer Health Disparities, suggests they have a positive view of the treatment and m...

Children's National researchers develop novel anti-tumor vaccine

WASHINGTON, DCA novel anti-tumor vaccine for neuroblastoma and melanoma developed by scientists and clinicians at Children's National Medical Center in collaboration with investigators from the University of Iowa is showing significant impact on tumor growth in mice, according to new research ...

Clinical trial for new tuberculosis vaccine

This release is available in German . Since Monday of this week, the new vaccine "VPM1002" has entered the clinical phase I trial in Neuss, Germany, where it is being tested for safety on voluntary subjects. VPM1002 is based on a vaccine that has been in use since 1921, and has been g...

Mobilizing white blood cells to the lung: New discovery could lead to an improved influenza vaccine

July, 10, 2008; Saranac Lake, N.Y. -- Findings just published in the scientific journal Immunity by researchers at the Trudeau Institute shed new light on how a previously-unknown messaging mechanism within the human immune system prompts specific influenza-fighting cells to the lung airways dur...

Penn researchers find monkeys able to fend off AIDS-like symptoms with enhanced HIV vaccine

(PHILADELPHIA) Researchers at the University of Pennsylvania School of Medicine have discovered that using an immune system gene to enhance a vaccine used to study HIV in macaque monkeys provides the animals with greater protection against simian HIV (SHIV) than an unmodified vaccine. This multi-...

Possible hepatitis C vaccine

Hepatitis C Virus (HCV) infects up to 500,000 people in the UK alone, many of the infections going undiagnosed. It is the single biggest cause of people requiring a liver transplant in Britain. Now, in a collaborative effort with groups across Europe and the USA, scientists from The University of ...

Innovative smallpox vaccine research study to be conducted at Case Medical Center

University Hospitals Case Medical Center (UHCMC) and Case Western Reserve University School of Medicine are part of a nationwide research study to determine the safety and effectiveness of a new smallpox vaccine geared toward adults ages 18 to 34 who have never been vaccinated against the disease....