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Vaccination in Biological News

New study indicates smallpox vaccination effective for decades

New York, December 1, 2008 Although naturally occurring smallpox was eradicated in 1977, there is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. Under such circumstances, the supply of smallpox vaccine may be insufficient for universal admin...

Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack

Mass vaccination would not be necessary in the event of a large-scale smallpox bioterrorist attack in the United States, according to a study led by researchers at Fred Hutchinson Cancer Research Center that appears online in the International Journal of Infectious Diseases. Instead, the current ...

Johns Hopkins flu expert calls for mandatory vaccination of health care workers

Johns Hopkins' senior hospital epidemiologist and flu expert is calling for mandatory vaccination of all health care workers as the best means of protecting patients and hospital staff from widespread outbreaks of the viral illness. Studies by other United States researchers show that voluntary va...

Polio vaccination strategies assessed as eradication nears

Polio is on track to become only the second disease ever eradicated. In two studies in the Dec. 15 issue of The Journal of Infectious Diseases, now available online, scientists are working to ensure that once it is gone, it stays gone. One study reduces concerns that people whose immune systems wer...

Genetic factors are linked to fever following smallpox vaccination

New evidence supports the link between genetic factors and certain adverse events related to smallpox vaccination. The study, published in the July 15th issue of The Journal of Infectious Diseases, now available online, may have implications for predicting adverse events from other live vaccines....

More than half of Texas physicians do not always recommend HPV vaccine to girls

...tion Practices recommends the human papillomavirus vaccination for all 11- and 12-year-old girls, but results of ... controversy early on with a mandate for universal vaccination from the governor's office, followed by a swift re...efforts to assess educational needs related to HPV vaccination among Texas physicians. Kahn and colleagues survey...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

... of 4.5 years (range 2.4 to 7.4) for the 30 surviving patients. Although not a direct comparison, the results are superior to those observed following vaccination with irradiated tumor cells in 48 melanoma patients in a previous trial (64 vs. 31 months, p=.016). Eight patients in the dendritic cell vaccine study...

Bioterrorism and disaster preparedness explored in special issue of Medical Decision Making

... in disaster response, and good model reporting of the disaster response. "Evaluating the Capability and Cost of a Mass Influenza and Pneumococcal vaccination Clinic via Computer Simulation" This research set out to determine the best way a clinic could vaccinate as many as 15,000 clients in 17 hours, in...

Ethiopian government celebrates rinderpest eradication

...ving in remote, marginalized areas of Ethiopia as community-based animal health workers (CAHWs). Most could not read or write, but mastered the cattle vaccination process by attending special training courses in the field, designed by Ethiopia's Ministry of Agriculture and Rural Development (MoARD) and Tufts vet...

Penn-Wistar team gains insight into HIV vaccine failure

...nd no significant difference in activation or expansion of CD4 T-cells in either the high- or the low-Ad5 antibody groups. "It doesn't appear that vaccination increases the pool of potentially infectable CD4 T-cells in people with pre-existing immunity to Ad5," Ertl says. "When you look at the data together,...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...g topics: The role of genetic factors in adult ADHD The future of schizophrenia Are the monoamines involved in shaping conduct disorder? vaccination for Alzheimers disease in dementia Novel treatment for smoking Maternal serotonin Deep Brain Stimulation (DBS): new perspectives for treatment ...

Tips from the journals of the American Society for Microbiology

... and Chemotherapy , 53. 6: 2510-2516.) New vaccination Strategy May Protect Against Both Lethal 1918 and ...N1 Influenza Viruses A new study suggests that vaccination with 1918 H1N1 influenza virus-like particles not ...otected against the 1918 viral challenge. Mucosal vaccination with 1918 VLPs induced higher levels of cross-reac...

Targeting children effective use of limited supplies of flu vaccine and could help control flu spread

...ousehold needs to be vaccinated, but suggests that vaccination programmes for children might help control a poten... The researchers argue that targeting children for vaccination would not only help protect those at greatest risk... particular risk from the disease, we believe that vaccination programmes for the young can be justified," says D...

Amarna Therapeutics B.V. and TNO announce SVac research and development partnership

...eases of our time including genetic disorders, autoimmune diseases, allergies and cancer. Amarna Therapeutics acts at the forefront of the therapeutic vaccination and gene therapy markets. Both markets are rapidly growing to reach an estimated 40 billion Euro’s in 2015. I’m convinced that the therape...

Government of Canada announces funding for research on the H1N1 flu virus

...andemic vaccine evaluation. The network will strengthen Canada's capacity to evaluate the safety and effectiveness of a pandemic influenza vaccine and vaccination programs. The network was created through a partnership between the Canadian Institutes of Health Research (CIHR) and the Public Health Agency of C...

Cost-effective measures could stop child pneumonia deaths

... control strategies. Programs to promote better community-based treatment of pneumonia, promotion of exclusive breastfeeding, zinc supplementation and vaccination for Hib and S. pneumoniae were found to be the most cost-effective interventions. The burning of solid fuels like wood, for cooking and heating, was f...

22nd Congress of the European College of Neuropsychopharmacology

...ng topics: The future of schizophrenia The role of genetic factors in adult ADHD Is the monoamines involved in shaping conduct disorder? vaccination for Alzheimers disease in dementia Novel treatment for smoking Maternal serotonin Deep Brain Stimulation: new perspectives for treatment News ...

Personalized treatment for early lung cancer

...which patients will benefit from the treatment. "Because the benefits of vaccination will be limited to a subgroup of patients, strategies to define these patie...of major clinical relevance, as only these patients might be candidates for vaccination in the future." A larger, phase III, trial of the vaccine is now underway. ...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

...atients whose tumors expressed MAGE-A3, preliminary results showed that the vaccination reduced the risk of recurrence and the need for repeat surgery." The vaccination may be a promising alternative treatment solution for lung cancer patients ...

A recipe for dog bite injuries: Kids, dogs and warm weather

...gression, ownership and owner's use of restraint, time of the incident, the child's past history of dog bites, location of the incident and the dog's vaccination history. "This information is important to be able to identify trends and develop and promote prevention strategies," says Behar. ...

HPV vaccine may prevent preterm births

...d 220 preterm births per 100 000 births could be caused by surgical treatment. Nearly 60 % of these may be prevented by the HPV-vaccine, assuming that vaccination coverage is 90 %. This would mean that 35-128 preterm births per 100 000 births could be avoided. If 4 % of pregnant women are treated with conisation...

African-Americans aware and accepting, but often do not receive, the HPV vaccine

...blic Health is funding research to develop ways to increase the rate of HPV vaccination among those at highest risk. HPV vaccination prevents cervical cancer by inoculating against the human papillomavirus. ...

Fractional dose of scarce meningitis vaccine may be effective in outbreak control

... In view of the current shortage of meningococcal vaccines for Africa, the use of 1/5 fractional doses should be considered as an alternative in mass vaccination campaigns. The study's findings contributed to a 2007 WHO recommendation that a fractional dosing strategy be utilized in the event of severe vaccine ...

Flu shot protects kids -- even during years with a bad vaccine match

... this month. "Conservatively, we can estimate that vaccination for flu could prevent 2,250 hospitalizations and b...vaccinated compared to those who were not. Partial vaccination (receiving one shot when two are recommended) did ...n receive full vaccination. Receiving only partial vaccination has not been shown to protect children from flu, E...

ASU researchers receive NIH awards for studies of malaria and emergent disease

...b-Saharan Africa, Escalante says that little information presently exists with regard to its genetic diversity. Targeting parasite proteins, either by vaccination or chemotherapeutic drugs, requires an understanding of how the parasites have evolved and the extent and maintenance of their variation. "Our lon...

Avian flu threat: New approach needed

...backed by over $2bn of public money, has affected the livelihoods and businesses of millions. Markets have been restructured, surveillance and poultry vaccination campaigns implemented, and over two billion birds have died or been culled. Simultaneously substantial investment has been made in human and animal he...

Bird flu vaccine protects people and pets

... vaccine protects birds and mammals against different flu strains and can even be given to birds while they are still in their eggs, allowing the mass vaccination of wild birds. The emergence of bird flu has posed a major challenge to scientists designing vaccines as it can infect a number of different animal...

Researchers develop new self-training gene prediction program for fungi

...elp in developing and producing critical pharmaceuticals. Gene prediction can also help to identify potential targets for therapeutic intervention and vaccination against pathogenic fungi. "While we previously showed that our unsupervised training program worked well to predict genes in many eukaryotes, it d...

HPV DNA test identifies cervical pre-cancerous disease in developing countries with 90% success rate

...y carcinogenic Human Papilloma Virus and - because it is possible to stop the infectious cycle and therefore the disease - are completely preventable. vaccination against HPV shows promise for future generations and is currently being implemented in the UK, mostly in young school-aged girls. However, the curren...

Vaccine against HER2-positive breast cancer offers complete protection in lab

... of the native HER2 receptor structure. "With this vaccine, I am quite certain the receptor is functionally dead," she said. "The greatest power of vaccination is protection against initial cancer development, and that is our ultimate goal with this treatment," Wei said. ...

Midge-hunting scientists tackle spread of devastating bluetongue virus

...est practice for use of insecticides and timing of vaccination of animals against this economically important and...hardship both to directly affected farmers and, if vaccination coverage is poor, to those living in neighbouring ...ed areas of the south east and East Anglia through vaccination and vigilance but we know that we couldn't have ac...

Immune system protein accurate predictor of survival in pediatric septic shock

...ulty breathing. The resulting condition, in which multiple organs malfunction, is called septic shock. Apart from antibiotics, supportive care and vaccination strategies, no specific therapies are approved by the FDA for pediatric septic shock. For their study, Dr. Wong and colleagues obtained blood seru...

Defining DNA differences to track and tackle typhoid

...hope that these mapping data can be used to target vaccination campaigns more successfully with the aim of eradic... dead end in humans. "We believe that concerted vaccination programmes, combined with epidemiological studies ...is causing infection, identify carriers and direct vaccination programmes most efficiently. It is a remarkable st...

Identification of protein able to stimulate production of T-cells

...e age-related decline of the immune system. "Thymic atrophy is a major public health problem," said Dr. Perreault. "It compromises the efficacy of vaccination and weakens the resistance to common viruses, for instance to the respiratory syncytial virus (RSV), which is responsible each year for the hospitaliz...

A step forward in virology

... especially among the indigenous population of North America who became infected by European settlers. Pox was the first viral disease against which a vaccination was developed. In 1771, the first rudimentary vaccine was produced from cowpox viruses, which protected people from the sequelae of the disease. Since...

Effective cancer immune therapy through order in the blood vessels

...mals were still alive after 48 weeks into the investigation, all animals with normal Rgs5 formation had died from cancer after 35 weeks at the latest. vaccination with tumor-specific proteins also resulted in improved survival times of Rgs5-deficient mice, while it showed no effect in control animals. We wer...

Biomarkers allow doctors to match therapy to patient

...= 0.02). Following vaccination, immunologic responses were similar as measured by delayed-type hypersensitivity reaction; however, patients in the vaccination arm who were low-expressors of HER2 demonstrated an increased number of E75-specific CD8+ T cells when compared with the vaccinated over-expressors. ...

Mesothelin engineered on virus-like particles provides treatment clues for pancreatic cancer

... single drug is not effective. Yao and her colleagues are seeking U.S. Food and Drug Administration approval to begin studies using their vaccination on people suffering from pancreatic cancer. ...

Prostate cancer: Watchful wait or vaccinate?

... stomach. The researchers created a prime-boost vaccination scheme using two kinds of vaccines and tested it i... by an army of immune system cells, Kast said. The vaccination turned the cancer into a chronic, manageable disease. The vaccination strategy also works with other antigens, Kast says...

Texas Hospital nation's first to use large-scale 'cocoon strategy' against whooping cough

...al announced that it will implement the nations first major cocoon strategy vaccination program to protect newborn infants from the life-threatening infection pert...ce serious pertussis disease in our community. Using the cocoon strategy vaccination model to prevent whooping cough has been recommended by the CDC since 2006,...
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