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Tumors in Biological News

Cancer-causing protein can also help fight the tumors it causes

Oncogenes are genes that when mutated or expressed in high concentrations can cause normal cells to become cancerous. Now research from Tel Aviv University is demonstrating that Ras, one of the first oncogenes discovered, has the power to heal as well as harm. Ph.D. student Oded Rechavi and hi...

Novel technique for fluorescence tomography of tumors in living animals

Fluorescent molecules i.e. substances which can be stimulated to emit light are extremely valuable tools in biological research and medical diagnosis. Fluorescence can be used for instance to analyze the regulation and expression of genes, to locate proteins in cells and tissues, to follow metab...

Slipping through cell walls, nanotubes deliver high-potency punch to cancer tumors in mice

The problem with using a shotgun to kill a housefly is that even if you get the pest, you'll likely do a lot of damage to your home in the process. Hence the value of the more surgical flyswatter. Cancer researchers have long faced a similar situation in chemotherapy: how to get the most medica...

Synthetic cocoa chemical slows growth of tumors in human cell lines

Washington, D.C. A synthetic chemical based on a compound found in cocoa beans slowed growth and accelerated destruction of human tumors in laboratory studies, and should be tested further for cancer chemoprevention or even treatment, say researchers at Georgetown University Medical Center. "We...

New type of drug shrinks primary breast cancer tumors significantly in just 6 weeks

Berlin, Germany: A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6) today (Thursday 17 Ap...

Veterinary college researcher studying brain tumors in people and animals

Blacksburg, Va. -- A veterinary neurologist on faculty in the Virginia-Maryland Regional College of Veterinary Medicine( www.vetmed.vt.edu ) at Virginia Tech has been awarded funding from the Wake Forest University Translational Science Institute to study innovative approaches for treating brain t...

Cell response to stress signals predicts tumors in women with common pre-breast cancer

A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS. This information could potentially be used in a clinical setting to determine which ...

Tumor suppressor gene in flies may provide insights for human brain tumors

SINGAPORE and DURHAM, N.C. In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor. Researchers at Duke-NU...

Protein linked to change in tissue that surround and support breast tumors

Washington, DC A protein known to be overly active in breast cancer can exist in a form that seems to change the structural composition of mammary tissue, potentially making it more conducive to tumor progression, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown Univers...

TGen researchers discover possible way to block the spread of deadly brain tumors

PHOENIX, Ariz. April 17, 2009 Researchers at the Translational Genomics Research Institute (TGen) may have found a way to stop the often-rapid spread of deadly brain tumors. A gene with the playful-sounding name NHERF-1 may be a serious target for drugs that could prevent malignant tumors fro...

SIRT1 takes down tumors

Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division. The study will be published online April 13 ( www.jcb.org ) and will appear in the April 20 print issue of the Journal of Ce...

UNC study: Scientists identify chemical compound that may stop deadly brain tumors

CHAPEL HILL Researchers at the University of North Carolina at Chapel Hill School of Medicine have identified a compound that could be modified to treat one of the most deadly types of cancer, and discovered how a particular gene mutation contributes to tumor growth. The findings and potential...

University of Kansas graduate student researcher takes aim at deadly brain tumors

LAWRENCE, Kansas Natalie Ciaccio, a fourth-year graduate student researcher in the Department of Pharmaceutical Chemistry at the University of Kansas, is investigating what might be an ideal target for anti-cancer drug therapy, and she is focusing her work on brain tumors specifically. The Na...

Freezing kidney cancer: Hot treatment should be new gold standard for destroying small tumors

SAN DIEGO, Calif. (March 9, 2009)Freezing kidney tumorsusing a safe minimally invasive interventional radiology treatment that kills the cancer 100 percent effectively without surgeryshould be the gold standard or first treatment option for all individuals with tumors that are 4 centimeters in siz...

Stress may hasten the growth of melanoma tumors

COLUMBUS, Ohio For patients with a particularly aggressive form of skin cancer malignant melanoma stress, including that which comes from simply hearing that diagnosis, might amplify the progression of their disease. But the same new research that infers this also suggests that the use of co...

Implants mimic infection to rally immune system against tumors

CAMBRIDGE, Mass., Jan. 22, 2009 -- Bioengineers at Harvard University have shown that small plastic disks impregnated with tumor-specific antigens and implanted under the skin can reprogram the mammalian immune system to attack tumors. The research -- which ridded 90 percent of mice of an aggre...

UC Davis researchers find molecule that targets brain tumors

(SACRAMENTO, Calif.) UC Davis Cancer Center researchers report today the discovery of a molecule that targets glioblastoma, a highly deadly form of cancer. The finding, which is published in the January 2009 issue of the European Journal of Nuclear Medicine and Molecular Imaging , provides hope ...

2 new compounds show promise for eliminating breast cancer tumors

Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up...

Two new compounds show promise for eliminating breast cancer tumors

Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up...

Purple tomatoes: The richness of antioxidants against tumors

Researchers from the John Innes Centre in Norwich, Great Britain, in collaboration with other European centres participating to the FLORA project, have obtained genetically modified tomatoes rich in anthocyanins, a category of antioxidants belonging to the class of flavonoids. These tomatoes, adde...

Design of a compound that stabilizes the main natural suppressor of tumors

This press release is available in Spanish . An interdisciplinary team of researchers, headed by Ernest Giralt at the Institute for Research in Biomedicine (IRB Barcelona) and Javier de Mendoza at the "Institut Catal d'Investigaci Qumica" (ICIQ, Tarragona), have discovered a substance with ...

Colorful spy tactics track live cells supporting cancerous tumors

A new advance in cellular imaging is allowing scientists to better understand the movement of cells in the area around tumors, also known as the tumor microenvironment. In a recent article published in Disease Models & Mechanisms (DMM), dmm.biologists.org , Zena Werb and colleagues used optimiz...

Researchers develop nano-sized 'cargo ships' to target and destroy tumors

Scientists have developed nanometer-sized 'cargo ships' that can sail throughout the body via the bloodstream without immediate detection from the body's immune radar system and ferry their cargo of anti-cancer drugs and markers into tumors that might otherwise go untreated or undetected. In a ...

Retraining immune cells to kill tumors

Immune cells called macrophages can destroy tumor cells by producing inflammatory proteins that are toxic to the tumor. But the environment inside the tumor somehow halts this production and instead causes the cells to make proteins that promote tumor growth. The new study identifies a protei...

Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors

Berlin, Germany: The first study to investigate the effects of chemotherapy on metastatic breast cancer in women with the BRCA1 or BRCA2 gene mutation has shown that standard chemotherapy works better in these patients than in women without the BRCA1/2 mutation. The authors of a study presente...

Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors

CINCINNATI Researchers in a multi-institutional study led by Cincinnati Childrens Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers neuroblastoma and peripheral nerve sheath tumors without harming healthy tissues by inserting instructions to inhibit tissue...

Genetic breakthrough offers promise in tackling kidney tumors

A new study has shown promising results in fighting a severe genetic disorder which can create tumours throughout the body. Advances in genetic knowledge have transformed our understanding of disease in recent years. We now know which genes are linked to a wide variety of conditions. However, s...

DNA methylation shown to promote development of colon tumors

CAMBRIDGE, Mass. (December 1, 2007) Damaged or defective genes have long been known to be the cause of some cancers. Over the past decade, however, scientists have discovered that even healthy genes can be switched on or off and can cause cancer without any changes in the underlying DNA sequencea...

New X-ray technique targets terrorists and tumors

Scientists at The University of Manchester have developed a new x-ray technique that could be used to detect hidden explosives, drugs and human cancers more effectively. Professor Robert Cernik and colleagues from The School of Materials have built a prototype colour 3D X-ray system that allows...

MIT: Remote-control nanoparticles deliver drugs directly into tumors

CAMBRIDGE, MA--MIT scientists have devised remotely controlled nanoparticles that, when pulsed with an electromagnetic field, release drugs to attack tumors. The innovation, reported in the Nov. 15 online issue of Advanced Materials, could lead to the improved diagnosis and targeted treatment of c...

Synthetic compound promotes death of lung-cancer cells, tumors

DALLAS Nov. 12, 2007 Human lung-cancer tumors grown in mice have been shown to regress or disappear when treated with a synthetic compound that mimics the action of a naturally occurring death-promoting protein found in cells, researchers at UT Southwestern Medical Center report. The findings...

Analysis of breast and colon cancer genes finds many areas of differences between tumors

Researchers from University Hospitals (UH) Ireland Cancer Center and Case Western Reserve University School of Medicine are part of a new national study that has analyzed more than 18,000 genes, including 5,000 previously unmapped genes, from breast and colorectal tumors. The study, published onl...

Invasion of the brain tumors

Gliomas are highly malignant and invasive tumors with tendrils that extend far from the primary tumor site, rendering conventional therapies ineffective and leading to an invariably poor prognosis. In a new study published online this week in the open-access journal PLoS Biology, Angela Johnston, ...

Effect on breast tumors of DNA alternations in 3 genes described

Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation. Hypermethylation is a process that causes genes that promote normal cell growth to produce proteins th...

Researchers wake up viruses inside tumors to image and then destroy cancers

Researchers have found a way to activate Epstein-Barr viruses inside tumors as a way to identify patients whose infection can then be manipulated to destroy their tumors. They say this strategy could offer a novel way of treating many cancers associated with Epstein-Barr, including at least four d...

Targeting tumors the natural way

By mimicking Nature's way of distinguishing one type of cell from another, University of Wisconsin-Madison scientists now report they can more effectively seek out and kill cancer cells while sparing healthy ones. The new tumor targeting strategy, presented today (March 25) at the annual national...

Vaccine for brain tumors shows promising results

A vaccine for treating a recurrent cancer of the central nervous system that occurs primarily in the brain, known as glioma, has shown promising results in preliminary data from a clinical trial at UCSF Medical Center. Findings from the first group of six patients in the study, being conducted at...

Killing brain tumors from within: A 'Trojan horse' approach

A new method for targeting malignant brain tumors through inducing the cancerous cells to "commit suicide" has been developed by a team of researchers headed by a Hebrew University of Jerusalem professor of biochemistry. Alexander Levitzki, who is the Wolfson Family Professor of Biochemistry, ...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 15 edition of Clinical Cancer Rese...

Possible birthplace of malignant brain tumors identified

Researchers have found that abnormal stimulation of a cellular trigger that normally regulates replenishment of brain cells in adults causes invasive tumor-like growths in mice. Removing the abnormal stimulation causes the growths to regress--a finding the researchers said suggests a possible treat...
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