Discovery to aid in future treatments of third-world parasites
Saranac Lake, NY - Schistosomiasis, one of the most important of the neglected tropical diseases, is caused by infection with parasitic helminths of the genus Schistosoma . These parasites are long lived (>10 years) and dwell within blood vessels, where they produce eggs that become the focus of ...
Discovery may provide new treatments for alcohol dependence
Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have discovered a new brain mechanism involved in alcohol addiction involving the stomach hormone ghrelin. When ghrelin's actions in the brain are blocked, alcohol's effects on the reward system are reduced. It is an importa...
New tool for next-generation cancer treatments using nanodiamonds
A research team at Northwestern University has demonstrated a tool that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells.
The tool, called the Nanofountain Probe, functions in two different ways: in one mode, the probe acts like a fountain pen, wherein drug-co...
UC Davis team refines cancer treatments to reduce potential nerve damage
(SACRAMENTO, Calif.) While radiation treatments
deliver precise doses of high-energy X-rays to stop cancer cells from spreading or to shrink tumors, oncologists have become increasingly concerned about inadvertent exposures during head and neck cancer treatments
to nerves responsible for upper bo...
Sibling study could lead to better treatments for inherited form of colon cancer
SALT LAKE CITYResearchers at Huntsman Cancer Institute (HCI) believe they may be one step closer to understanding how certain forms of colon cancer develop.
In a study using siblings who have been diagnosed with colon cancer, scientists discovered similarities on a region of a particular chromo...
Research identifies first method for testing, assessing drug treatments for Chagas' disease
Athens, Ga. Chagas disease is a tropical parasitic sickness that currently affects more than 16 million people, with a staggering 100 million at risk, largely in the tropical areas of South and Central America. And yet the main drug used to treat the disease is highly toxic and causes serious sid...
European membrane expertise to focus on new treatments for human diseases
A new 15 million Euro project led by the University of Leeds aims to find novel treatments
for many human diseases by bringing together the leading European experts in membrane proteins.
The project the European Drug Initiative for Channels and Transporters (EDICT) will target about 80 protei...
Restoring sight, advances in fertility treatments and better visibility for pilots at FIO
WASHINGTON, Aug. 23 V Frontiers in Optics 2007 (FiO), the 91st Annual Meeting of the Optical Society of America, will be held from Sept. 16-20 in San Jose, Calif., alongside Laser Science XXIII, the annual meeting of the American Physical Society Division of Laser Science.
Reporters interested ...
New evidence of how high glucose damages blood vessels could lead to new treatments
AUGUSTA, Ga. New evidence of how the elevated glucose levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking the destruction, Medical College of Georgia researchers say.
They found a decreased ability of blood vessels to relax resulted from increased acti...
New orthopaedic society launched to promote research, use of biologic treatments
LAS VEGAS February 25, 2009 The first international society dedicated to the evaluation and use of new biologic treatments
for orthopaedic conditions has been formed.
The Biologic Orthopaedic Society (BOS; www.BiologicOrtho.com ) held its inaugural meeting Tuesday, February 24, 2009 at the V...
Research finds new cause of ozone wheezing and potential treatments
Researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, and Duke University have discovered a cause of airway irritation and wheezing after exposure to ozone, a common urban air pollutant. Using an animal model, the researchers wer...
Landmark study opens door to new cancer, aging treatments
(PHILADELPHIA)Researchers at The Wistar Institute have deciphered the structure of the active region of telomerase, an enzyme that plays a major role in the development of nearly all human cancers. The landmark achievement opens the door to the creation of new, broadly effective cancer drugs, as w...
Glypican-3 gene function in regulating body size helps inform novel cancer treatments
Toronto (May 13, 2008) - In a leading study that has implications for the development of novel therapies for a number of breast, lung and ovarian cancers that have lost the expression of a gene called glypican-3 (GPC3), Sunnybrook researchers have discovered how the loss of the GPC3 gene induces o...
Brain study may lead to improved epilepsy treatments
Using a rodent model of epilepsy, researchers found one of the bodys own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain. Researchers say this may explain why a...
Genes linked with lupus are revealed, giving hope for new treatments
Scientists have identified a number of genes involved in Lupus, a devastating autoimmune disease, in new research published today in the journal Nature Genetics.
In an international genetic study of more than 3,000 women, researchers found evidence of an association between Lupus (systemic lupu...
NIH selects LIAI for major study on allergy molecular causes and possible treatments
SAN DIEGO (November 13, 2007) A major study that will provide a new window into understanding and potentially treating allergies will be conducted by the La Jolla Institute for Allergy & Immunology (LIAI) under a $5 million federal contract. The five-year study, funded by the National Institute ...
Paradigm shift in Alzheimers's research: new treatments
Alzheimers disease (AD) is a progressive neurodegenerative disorder characterized by extensive neuronal degeneration and the development of neuritic amyloid plaques and neurofibrillary tangles. Neuronal and synaptic losses in AD are correlated with dementia and occur in specific brain areas involv...
Cheaper, better disease treatments expected from faster approach to developing antibodies
A method of mass-producing disease-fighting antibodies entirely within bacteria has been developed by a research group at The University of Texas at Austin.
The group led by Dr. George Georgiou developed the new antibody-production approach to improve upon processes used previously to identify n...
SARS: No evidence that any of the treatments worked
The SARS virus set alarm bells ringing across the world when it first appeared in 2002, but now a review of the effectiveness of the treatments
used against it has found no evidence that any of them worked. The review was commissioned by the World Health Organization and has been published in PLoS ...
New understanding of parasite cell structures may provide treatments for serious tropical diseases
Don't even think about trying to pronounce it. Although it is found in many organisms including humans, glycosylphosphatidylinositol has remained a mouthful for laymen and a puzzle for scientists. And yet GPIs, as science thankfully calls these cellular lipids, are important in numerous biological ...
Access to existing medical treatments could save more lives than spending to improve the treatments
More lives could be saved in the United States by spending less money on making medical treatments
better and more on getting existing treatments
to the patients who need them, according to a study published by a Virginia Commonwealth University family medicine and public health physician.
Minimally Invasive Cancer Treatments Highlighted
Clinicians and basic scientists from academia, private practice, government and industry are coming together for a week-long multi-disciplinary symposium in interventional oncology, a rapidly growing area of medicine involving minimally invasive interventional radiology treatments
Potential treatments for neurofibromatosis
Neurofibromatosis can leave its patients miserable and debilitated with chronic itching or pain from disfiguring tumors. Infants affected by the disease face possible paralysis or damage to the brain and other organs.
The disease frustrates doctors because there's no effective treatment even tho...
Effective Cancer Treatments Follow The Clock
Interesting application of chronopharmacology :
Oncologists have long thought that cancer treatments
tend to be more effective at certain times of day. But they have been unable to turn this knowledge into practice, because they did not understand the phenomenon well enough. Now, researche...
Women well informed about breast cancer, yet lacking knowledge about current treatments
According to a new GfK Roper Public Affairs survey sponsored by CancerCare, a national nonprofit cancer support organization, while the majority (76 percent) of women surveyed said they know at least a fair amount about breast cancer, many remain unaware of the important recent progress made in tr...
NIH stimulus funding supports Emory biomedical scientists
...essful projects that could soon be translated into treatments
for patients," says David Stephens, MD, vice presi...s could generate new tools to fight cancer.
Some epilepsy patients cannot contro...8A in mice, with an eye towards developing similar treatments
The role of memory T cells in trans...
Abnormal brain circuits may prevent movement disorder
... The identification of a specific abnormality in people with the genetic mutation who never develop symptoms could eventually pave the way towards new treatments
for dystonia patients. There are half a million people in the United States alone. The brains of people with inherited dystonia are normal at autopsy ...
New DNA and RNA aptamers offer unique therapeutic advantages
...gle strands of DNA or RNA, called aptamers, can bind protein targets with a high strength and specificity and are currently in clinical development as treatments
for a broad range of common diseases, as described in a comprehensive review article published online ahead of print in Oligonucleotides , a peer-rev...
Neuropathic pain: The sea provides a new hope of relief
...wan, could lead scientists to develop a new set of treatments
for neuropathic pain chronic pain that sometimes ... (NSAIDS) or even opioids like morphine) and novel treatments
are urgently required. The conclusion of a paper ...ely affecting the person's quality of life.
that give some relief to some patients are a very ...
Brain difference in psychopaths identified
...ientists the potential to move towards a more coherent understanding of the possible brain networks that underlie psychopathy, and potentially towards treatments
for this mental disorder.'
New stem cell research could reduce number of animal experiments
...If we are to reduce animal use and at the same time continue to develop new treatments
for diseases then we must engage the best minds and harness the best scienc... really pleased to be giving grants to scientists who are trying to develop treatments
in major areas of concern such as cancer, motor neurone disease and Alzheim...
Scientists open doors to diagnosis of emphysema
...tegy can be extended to other enzymes involved in lung inflammation and that, with a better picture of the processes underlying these diseases, future treatments
could be more specific, reducing the side-effects often caused by broad spectrum treatments.
Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers
...f glioblastoma cells, preventing a growth factor protein from binding to it and activating growth pathways in the tumors.
"We desperately need new treatments
for glioblastoma, and these findings have given us hope that a new approach may be possible," says the study's lead investigator, Anton Wellstein, MD,...
Scientists uncork a potential secret of red wine's health benefits
...r-in-Chief of The FASEB Journal , "and now that scientists have uncorked its secrets, they find that studies of how resveratrol works can lead to new treatments
for life-threatening inflammation."
Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth
Although early stage ovarian cancer can be treated with a combination of surgery followed by chemotherapy, there are currently no effective treatments
for advanced ovarian cancer that has recurred after surgery and primary chemotherapy. Therefore, the majority of treated early stage cancers will rela...
Reprogramming human cells without inserting genes
... risks associated with inserting extra genes or using viruses. This discovery opens a new avenue for reprogramming cells that could eventually lead to treatments
for a range of human diseases and traumatic injuries by coaxing a patient's own cells to repair and regenerate the damaged tissues.
The research te...
Researchers design first model motor nerve system that's insulated and organized like the human body
...any conditions that are caused by a loss of myelin, which forms protective insulation around our nerves, can be debilitating and even deadly. Adequate treatments
do not yet exist. Researchers at the UCF have identified this to be a result of a deficiency in model research systems.
James Hickman, a bioengine...
C. difficile spores spread superbug
The results have implications for infection control measures in the healthcare environment and open the door for the development of treatments
and improved diagnosis of C. difficile .
At present, healthcare professionals manage the threat of C. difficile by observing stringent hygiene a...
UCLA researchers discover new molecular pathway for targeting cancer, disease
... the development of cancer and other diseases. The findings may lead to new treatments
and targeted drugs using this approach.
In the study, which is curren... tumor formation, and these findings suggest that LXR agonists may be novel treatments
for a wide variety of human cancers," Matsui said.
According to rese...
'Show me the money!' MDA greenlights grants
... Board R. Rodney Howell.
There are no cures yet for most muscle diseases, but the research MDA has funded has created the basis for progressive treatments
of muscular dystrophy, amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, and spinal muscular atrophy. It also served as the basis for a li...