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Tissue in Biological News

Skin-like tissue developed from human embryonic stem cells

BOSTON (July 21, 2009) Dental and tissue engineering researchers at Tufts University School of Dental Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have harnessed the pluripotency of human embryonic stem cells (hESC) to generate complex, multilayer tissues that mimic hu...

Stem cell surprise for tissue regeneration

Baltimore, MDScientists working at the Carnegie Institution's Department of Embryology, with colleagues, have overturned previous research that identified critical genes for making muscle stem cells. It turns out that the genes that make muscle stem cells in the embryo are surprisingly not needed ...

Protein linked to change in tissue that surround and support breast tumors

Washington, DC A protein known to be overly active in breast cancer can exist in a form that seems to change the structural composition of mammary tissue, potentially making it more conducive to tumor progression, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown Univers...

Dual role in breast tissue for a protein involved in leukemia

Washington, DC - A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC). The findings, presented at the annual ...

NIH funds work at WPI on regenerating heart tissue and preventing urinary tract infections

WORCESTER, Mass. May 28, 2009 Congressman James McGovern, D-Massachusetts, today announced National Institutes of Health (NIH) awards for two researchers at Worcester Polytechnic Institute's Life Sciences and Bioengineering Center at Gateway Park. Glenn Gaudette, PhD, assistant professor of b...

WPI professor receives Fulbright Scholarship to work on tissue engineering in Ireland

WORCESTER, Mass. Kristen L. Billiar, associate professor of biomedical engineering at Worcester Polytechnic Institute (WPI), has been awarded a Fulbright Scholarship to work at the National University of Ireland Galway on research and education related to tissue engineering. Billiar, who will be ...

MIT: New tissue scaffold regrows cartilage and bone

CAMBRIDGE, Mass.--MIT engineers and colleagues have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into the knees and other joints. The scaffold could offer a potential new treatment for sports injuries and other cartilage damage, such as arthritis, s...

NIST issues first reference material for tissue engineering

The National Institute of Standards and Technology (NIST) last week issued its first reference materials to support the new and growing field of tissue engineering for medicine. The new NIST materials are samples of a typical tissue scaffold material that have been measured and documented by NIST ...

Model tissue system reveals cellular communication via amino acids

A team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) has found the first evidence of cell-to-cell communication by amino acids, the building blocks of proteins, rather than by known protein signaling agents such as growth factors or cytokines. ...

Therapeutic hypothermia is promising strategy to minimize tissue damage

New Rochelle, NY, March 19, 2009Recognition of the benefits of cooling strategies to protect the brain and spinal cord after traumatic injury has led to a wealth of cutting edge research, prime examples of which are featured in a special hypothermia issue of Journal of Neurotrauma , a peer-review...

Stem cells replace stroke-damaged tissue in rats

Effective stem cell treatment for strokes has taken a significant step forward today (09 March) as scientists reveal how they have replaced stroke-damaged brain tissue in rats. The team of scientists is funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and led by Dr M...

High-fat diets inflame fat tissue around blood vessels, contribute to heart disease

CINCINNATIA study by researchers at the University of Cincinnati (UC) shows that high-fat diets, even if consumed for a short amount of time, can inflame fat tissue surrounding blood vessels, possibly contributing to cardiovascular disease. These findings will be published in the Feb. 20 editio...

Advancement in tissue engineering promotes oral wound healing

Tampa, Fla. (Feb. 3rd, 2009) Oral tissue engineering for transplantation to aid wound healing in mouth (oral cavity) reconstruction has taken a significant step forward with a Netherlands-based research team's successful development of a gum tissue (gingival) substitute that can be used for recon...

Building better bones and tissue in the lab

Tissue engineering holds great promise for the treatment of conditions such as arthritis, osteoporosis, fibrosis, periodontal disease and traumatic injuries. However, bone and cartilage currently produced in the laboratory don't have sufficient strength to function in the body so they're not clin...

Single adult stem cell can self renew, repair tissue damage in live mammal

The first demonstration that a single adult stem cell can self-renew in a mammal was reported at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco. The transplanted adult stem cell and its differentiated descendants restored lost function to mi...

MIT: Mending broken hearts with tissue engineering

CAMBRIDGE, Mass.--Broken hearts could one day be mended using a novel scaffold developed by MIT researchers and colleagues. The idea is that living heart cells or stem cells seeded onto such a scaffold would develop into a patch of cardiac tissue that could be used to treat congenital heart de...

NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves

CLEMSON The National Institutes of Health (NIH) has awarded Naren Vyavahare, Hunter Endowed Chair and professor of bioengineering at Clemson University, more than $1.5 million over four years to develop durable bioprosthetic heart valves (BHVs). Aortic valves taken from pigs are used in thousa...

Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering

At 30, Karen Christman, an assistant bioengineering professor at the UC San Diego Jacobs School of Engineering, plans to help fuel the growing field of tissue engineering. With a new $1.5 million New Innovator Award grant from the National Institutes of Health (NIH), Christman will be able to do j...

New technique sees into tissue at greater depth, resolution

DURHAM, N.C. By coupling a kicked-up version of microscopy with miniscule particles of gold, Duke University scientists are now able to peer so deep into living tissue that they can see molecules interacting. If future studies in animal models prove fruitful, the researchers believe that their...

Fly studies reveal immune cell responses to tumor and tissue damage

September 17, 2008, Cambridge, UK Knee scrapes and tumor growth might have more in common than you think. The idea that tumor growth triggers the same immune response as a cut or wound was once a highly controversial notion. However, increasing evidence supports the idea that the same ce...

Human embryonic stem cell secretions minimized tissue injury after heart attack

A novel way to improve survival and recovery rate after a heart attack was reported in the journal Stem Cell Research by scientists at Singapore's Institute of Medical Biology (IMB) and Bioprocessing Technology Institute (BTI) and The Netherlands' University Medical Center Utrecht. This meth...

Cardiac cell transplant studies show promise in cardiac tissue repair

Tampa, Fla. (Sep. 3rd, 2008) Two studies published in the current issue of CELL TRANSPLANTATION (17:6) examine the efficacy of transplanting bone marrow cells (BMCs) for the repair of heart tissue. The first study found that implanting adult cardiomyocytes (heart muscle cells) in combination...

Dense tissue promotes aggressive cancers

New research may explain why breast cancer tends to be more aggressive in women with denser breast tissue. Breast cancer cells grown in dense, rigid surroundings step up their invasive activities, Vanderbilt-Ingram Cancer Center investigators report in the Sept. 9 issue of Current Biology . The...

Senescence in liver cells is found by CSHL scientists to help limit acute tissue damage

Although post-reproductive life in humans is often associated with decline and a loss of powers, an analogous state in certain cells -- called senescence -- is proving to be one of ironic potency. Scientists at Cold Spring Harbor Laboratory (CSHL) today reported that a particular class of senesce...

QUT researchers develop smart instrument for tissue damage assessment

Professor Oloyede said that the device, which he calls a "smarthroscope", may be able to reduce the cost of surgery, eliminate unnecessary surgery, and could be useful in developing countries. It aims to determine the degree and spread of damage to the tissue surrounding an area affected by ill...

New mechanical insights into wound healing and scar tissue formation

New research published today in the Journal of Cell Biology illuminates the mechanical factors that play a critical role in the differentiation and function of fibroblasts, connective tissue cells that play a role in wound healing and scar tissue formation. When we are injured, the body launch...

Setting a course for the future of tissue engineering

New Rochelle, NY, December 11, 2007 The editors of Tissue Engineering asked 24 leaders in the field what critical steps are needed for tissue engineering to achieve broad critical success by the year 2021 and published their findings in the December 2007 issue (Volume 13, Number 12). Tissue Engine...

Human embryonic stem cell -- derived bone tissue closes massive skull injury

There are mice in Baltimore whose skulls were made whole again by bone tissue grown from human embryonic stem cells (hESCs). Healing critical-size defects (defects that would not otherwise heal on their own) in intramembraneous bone, the flat bone type that forms the skull, is a vivid demonstr...

Raydiance collaborates with Rutgers, MTF to develop innovative tissue processing approaches

Petaluma, CA and New Brunswick, NJ, November 19, 2007 Raydiance, Inc. today announced that is has entered into an innovative collaboration with Rutgers University and the Musculoskeletal Transplant Foundation (MTF), the nations largest tissue bank, to improve the science of dermal tissue processi...

Breast cancer research and inkjet tissue printing get NSF boost

CLEMSON The National Science Foundation (NSF) has awarded $2 million to the Center for Biological Interfaces of Engineering (CBIOE) at Clemson University for the development of engineered tissues that will be used to study the causes, progression and treatment of breast cancer. The tissue engi...

Intravenous gene therapy protects normal tissue of mice during whole-body radiation

LOS ANGELES, Oct. 28 Gene therapy administered intravenously could be an effective agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological or nuclear bomb, according to an animal study presented today by University ...

Natural product discovery by Cleveland medical researchers blocks tissue destruction

CLEVELAND Scientists at Case Western Reserve Universitys School of Medicine have published in the Journal of Inflammation a remarkable discovery with a natural product derived from the Amazon rainforest. The discoverys unique actions suggest a broad set of applications in various joint, skin and ...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

BUFFALO, N.Y. -- University at Buffalo researchers have demonstrated for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart failure. Using an animal model, the researchers showed that this non-invasive procedure increased...

Non-wovens as scaffolds for artificial tissue

This release is available in German . When someone's knee hurts with every step it's a sign that the cartilage has been so badly damaged that the bones rub together when walking. Medical scientists are developing a technique to produce cartilage tissue artificially so that patients with ...

Lithium may help radiation target cancer, spare healthy tissue

Vanderbilt-Ingram Cancer Center investigators have uncovered a mechanism that helps explain how lithium, a drug widely used to treat bipolar mood disorder, also protects the brain from damage that occurs during radiation treatments. In the May 1 issue of the Journal of Clinical Investigation ,...

Gene therapy appears safe to regenerate gum tissue

ANN ARBOR, Mich.---Scientists at the University of Michigan have developed a method of gene delivery that appears safe for regenerating tooth-supporting gum tissue---a discovery that assuages one of the biggest safety concerns surrounding gene therapy research and tissue engineering. Gene ther...

Columbia University scientist devises new way to more rapidly generate bone tissue

NEW YORK (Dec. 15, 2008) Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues. The inability to foster angiogenesis a physiological process involving the growth of new blood vessels from pre-ex...

Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue

PHILADELPHIA - Biophysicists at the University of Pennsylvania have used 3,200 computer processors and long-established data on cholesterol's role in the function of proteins to clarify the mysterious interaction between cholesterol and neurotransmitter receptors. The results provide a new model o...

'Buckyballs' have high potential to accumulate in living tissue

WEST LAFAYETTE, Ind. - Research at Purdue University suggests synthetic carbon molecules called fullerenes, or buckyballs, have a high potential of being accumulated in animal tissue, but the molecules also appear to break down in sunlight, perhaps reducing their possible environmental dangers. ...

2 beta blockers found to also protect heart tissue

DURHAM, N.C. A newly discovered chemical pathway that helps protect heart tissue can be stimulated by two of 20 common beta-blockers, drugs that are prescribed to millions of patients who have experienced heart failure. Researchers from Duke University Medical Center tested 20 beta blockers a...
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