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New therapy substitutes missing protein in those with muscular dystrophy

Researchers at the University of Minnesota Medical School have discovered a new therapy that shows potential to treat people with Duchenne muscular dystrophy, a fatal disease and the most common form of muscular dystrophy in children. In the mouse model, researchers were able to substitute for ...

Genetic differences between yeasts greater than those between humans and chimpanzees

The mapping of the entire yeast genome in 1996 marked the beginning of a revolution in biological and medical research. The human genome was mapped in 2001, and by now the number of characterised species is approaching 1000, most of which are bacteria. The next advance is only a few years away ma...

Protecting those who heal

Patients are not the only ones at risk during cardiac procedures. Doctors performing heart surgery also face health risks, namely to their eyes. The IAEA is helping to raise awareness of threats, through training in radiation protection related to medical uses of X-ray imaging systems. The i...

Children born from frozen embryos weigh more and do better than those born after fresh transfer

This release is available in Spanish . Barcelona, Spain: Children born after a frozen, thawed embryo has been replaced in the womb have higher birth weight than those born where fresh embryos were used, Danish scientists reported to the 24th annual conference of the European Society of H...

Neural cell transplants may help those with Parkinson's disease

Tampa, Fla. (May 19, 2008) The current issue of CELL TRANSPLANTATION (Vol. 17:4) features a number of publications by researchers seeking new ways to treat Parkinsons disease (PD), a neurological disease characterized by muscle rigidity, tremor and slowed physical movements related to insufficien...

U of M finds teens who eat breakfast daily eat healthier diets than those who skip breakfast

University of Minnesota School of Public Health Project Eating Among Teens (EAT) researchers have found further evidence to support the importance of encouraging youth to eat breakfast regularly. Researchers examined the association between breakfast frequency and five-year body weight change in m...

Cigarette smoking may accelerate disability in those with MS

BUFFALO, N.Y. -- Persons with multiple sclerosis who smoke risk increasing the amount of brain tissue shrinkage, a consequence of MS, and the subsequent severity of their disease, new research conducted at the Buffalo Neuroimaging Analysis Center (BNAC) at the University at Buffalo has shown. Th...

Older men treated for early prostate cancer live longer than those who are not

Recent findings from an observational study by researchers at the University of Pennsylvania School of Medicine suggest that men between 65 and 80 years of age who received treatment for early stage, localized prostate cancer lived significantly longer than men who did not receive treatment. The st...

Light-sensitive photoswitches could restore sight to those with macular degeneration

A research center newly created by the University of California, Berkeley, and Lawrence Berkeley National Laboratory (LBNL) aims to put light-sensitive switches in the body's cells that can be flipped on and off as easily as a remote control operates a TV. Optical switches like these could trigge...

New discovery blurs distinction between human cells and those of bacteria

UCLA biochemists reveal the first structural details of a family of mysterious objects called microcompartments that seem to be present in a variety of bacteria. The discovery was published Aug. 5 in the journal Science. "This is the first look at how microcompartments are built, and what the pie...

New Lab Research May Help Those Deafened By Immune System Attack

Our immune system protects us from disease, destroying invading microbes with a swarm of attacking cells. But it can also go haywire for no apparent reason, ganging up on normal tissues in our body and wreaking havoc. In thousands of people each year, the immune system attacks the inner ear, home...

One gene links newborn neurons with those that die in diseases such as Alzheimer's

In certain parts of the brain, cells called neurons go through a cycle of death and replenishment. New research from Rockefeller University's Fernando Nottebohm, Ph.D., shows that these replaceable neurons share something in common with the neurons that die in people with diseases such as Alzheimer...

Mouse brain tumors mimic those in human genetic disorder

A recently developed mouse model of brain tumors common in the genetic disorder neurofibromatosis 1 (NF1) successfully mimics the human condition and provides unique insight into tumor development, diagnosis and treatment, according to researchers at Washington University School of Medicine in St. ...

Advances in lung cancer research announced at conference

...s many as 1 in 4 patients. The ability to identify those at risk for developing brain metastasis may guide ...uticals of Redwood City, Calif. In the study of those treated only with TH-302, six of eight, or 75 perc...chieved stable disease or better." In the study of those treated with TH-302 in combination with other chem...

New cancer drug delivery system is effective and reversible

...ncer cells, liposomes can enter and dump their cancer-killing contents into those cells. Scientists have spent more than a decade trying to direct liposom...les, such folate, a vitamin, also work as cancer cell targeting agents, but those now in use are not as good as antibodies at binding to cancer cells. To ...

Symposium to discuss geoengineering to fight climate change at the ESA Annual Meeting

..., ocean fertilization schemes will likely exacerbate this problem. "Any large-scale fertilization could cause risks to ocean ecosystems as great as those of global warming itself," he says. Despite its apparent hazards at the global scale, Jackson thinks that research should continue on safer ways to...

Moving to the US increases cancer risk for Hispanics

...ispanics living in the United States compared with those who live in their countries of origin. Colorectal ...xican and Puerto Rican Floridian women compared to those in Mexico or Puerto Rico. "This suggests that c... easier, including access to health care, are also those with higher cancer rates even after accounting for...

More than half of Texas physicians do not always recommend HPV vaccine to girls

...dictors of vaccine recommendation, they found that those in an academic vs. non-academic practice were more than twice as likely to recommend the vaccine. those who considered professional organizations or profe...most twice as likely to recommend the vaccine than those who did not consider these sources valuable. "...

Women often opt to surgically remove their breasts, ovaries to reduce cancer risk

...women were much less likely to have a mastectomy, but were more likely to have their ovaries removed," said Evans. Most of the women, specifically those aged 35 to 45 years, opted for surgery within the first two years after the genetic mutation test, but some did not make a decision until seven years ...

Abnormal brain circuits may prevent movement disorder

...ty of white matter pathways in the brain to study those with and without symptoms who carry the disease ge...duals had such difficulties since doctors only saw those who presented with the uncontrollable movements. ...signals from one part of the circuit to the other. those with only one lesion in the circuit developed the ...

Understanding how weeds are resistant to herbicides

...years ago genomics was reserved for what Tranel refers to as "important species" such as humans, cows, fruit flies, and mice. "That's changed now that those species have been sequenced. Now we can start doing genomics on weeds to start understanding weeds better. "With this type of technology, you can g...

Hormone levels contribute to stress resilience

...dual's capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters. Dr. Charles A...more DHEA performed better during the final underwater navigation exam than those with less DHEA. These findings are being published by Elsevier in the Augu...

The way you eat may affect your risk for breast cancer

...n the control mice who ate the amount of food they wanted, 35 percent among those who were chronically restricted and only nine percent in those who intermittently restricted calories. The researchers were initially ...

Urban water ecology at the ESA annual meeting

...sphorous that originated from the sewage treatment plants. Likewise, in laboratory experiments, mosquitoes reared in sewage overflow were larger than those reared in clean water. "In this food web, mosquitoes feed on microorganisms that require nitrogen and phosphorous to grow," Chaves says. "This trans...

Race/ethnicity, family income and education associated with sugar consumption

...lgorithms to calculate number of teaspoons of added sugars consumed daily. This method provided values for average intakes of added sugars similar to those found from more detailed methods. ...

New hope for fisheries

... examined in detail. This means that management in those areas is setting the stage for ecological and econ...ra, California. The current paper is the result of those meetings. "Prior to this study, evaluations of...p's recommendations is to fish at rates lower than those producing maximum sustainable yield (MSY), a long-...

August 2009 Geology and GSA Today media highlights

... sources emplaced to depths of about 4 km or less. those in which most high Cu grades occur in narrow halos...ical results. While ice volumes of similar size to those implied by proxy evidence are simulated, sea-level...se changes observed among the fish faunas resemble those of conodonts, another extinct group of vertebrates...

UC San Diego engineer provides insights to decades-old DNA squabble

...atin around these genes leading to cancer." The next step for Arya and his team is to study the mechanisms by which chromatin is regulated, and how those lead to genes being switched "on" and "off," genes being repaired in response to mutations, and genes being replicated during cell division. Arya be...

Scientists decoding genomic sequences of H1N1 using isolates from outbreak in Argentina

...patients with severe respiratory disease. The scientists will be comparing sequences of viruses associated with the current outbreak in Argentina with those found in other locations to determine if there are differences that may be linked to higher mortality rates or provide insights into virus evolution. ...

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers

...elanoma and pancreatic tumors. "We have found that PTN drives metastasis of those cancers, suggesting that antibody treatment may be additionally useful in those cancers," Wellstein says. Researchers at Lombardi/Georgetown University ...

Global curbs on overfishing are beginning to work

...tion rate the ultimate driver of depletion and collapse is decreasing in half of the 10 systems we examined in detail. This means that management in those areas is setting the stage for ecological and economic recovery. It's only a start but it gives me hope that we have the ability to bring overfishing ...

Rodent size linked to human population and climate change

... collected from 1892 to 2001, and Pergams compared those from before 1950 to those collected after. He also compared specimens gathered from sparsely populated islands to those from the mainland, where human populations were de...

Got zinc? New zinc research suggests novel therapeutic targets

...ists then simulated infection in laboratory conditions. Results showed that T cells taken from the zinc-supplemented group had higher activation than those from the placebo group. Specifically, cell activation stimulated the zinc transporter in T cells called "ZIP8," which transports stored zinc into the...

U of M study identifies risk factors of disordered eating in overweight youth

...s from this study also suggest the importance of strong family relationships for overweight adolescents. These youth face pressures above and beyond those faced by their non-overweight peers due to strong social pressures to be thin. Lack of family connectedness, including not eating family meals togeth...

K-State researcher, collaborators study virulence of pandemic H1N1 virus

...ide collaborators is revealing the characteristics of the pandemic H1N1 virus. Richt is among the K-State researchers who study zoonotic disease -- those that can be transmitted from animals to humans and vice versa. Zoonotic diseases will be a focus of the National Agro and Bio-Defense Facility that ha...

UCSF researchers identify new drug target for Kaposi's sarcoma

...ral enzymes known as proteases, however, including those for HIV and the herpes virus family, take the form...ully opened clamshell in their most stable state. those proteases play an essential role in making the vir...ty of devastating illnesses, the researchers said. those include mononucleosis (Epstein-Barr virus), shingl...

A crystal ball for brain cancer?

...0 percent accuracy which patients' tumors would progress within six months and which would not. They detected greater water movement in the tumors of those persons who later responded best to Avastin. "When we realized that high levels of VEGF are linked to greater cell death and increased water moveme...

Reducing risk of hospitalization in the elderly

...elative risk for hospitizations was 50% higher for those with poor walking or less dense muscle mass "Ou...ants had experienced one or more hospitalizations. those most likely to end up in the hospital were the adu... adults with the least dense thigh muscles, namely those with a higher proportion of fat in their thighs, w...

Little-known protein found to be key player

...s. It expands. It collapses. It's highly dynamic, and for that to be the case, there has to be a mechanism by which it can grow new pieces and connect those pieces together. That's where the fusion comes in." Daga said the discovery will lay the foundation for a deeper understanding of both basic biolo...

New computer simulation helps explain folding in important cellular protein

...he energy density states that allow such folding? Perhaps remarkably, they did. The first step in studying the dimerization process was to estimate those states in GpA using Wang-Landau. The second step was to sample various energy and structural "observables" of the system to provide insights into the ...
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