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Small in Biological News

Nanoneedle is small in size, but huge in applications

CHAMPAIGN, Ill. Researchers at the University of Illinois have developed a membrane-penetrating nanoneedle for the targeted delivery of one or more molecules into the cytoplasm or the nucleus of living cells. In addition to ferrying tiny amounts of cargo, the nanoneedle can also be used as an ele...

Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

Cold Spring Harbor, N.Y. -- A key item in the developmental agenda of a plant leaf is the establishment of an axis that makes a leaf's top half distinct from its bottom half. This asymmetry is crucial for the leaf's function: it ensures that the leaf develops a flattened blade that is optimized fo...

Freezing kidney cancer: Hot treatment should be new gold standard for destroying small tumors

SAN DIEGO, Calif. (March 9, 2009)Freezing kidney tumorsusing a safe minimally invasive interventional radiology treatment that kills the cancer 100 percent effectively without surgeryshould be the gold standard or first treatment option for all individuals with tumors that are 4 centimeters in siz...

Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

Cold Spring Harbor, N.Y. -- A key item in the developmental agenda of a plant leaf is the establishment of an axis that makes a leaf's top half distinct from its bottom half. This asymmetry is crucial for the leaf's function: it ensures that the leaf develops a flattened blade that is optimized fo...

CSHL scientists find a new class of small RNAs and define its function

Cold Spring Harbor, NY Researchers at Cold Spring Harbor Laboratory (CSHL) announced today the discovery of a new class of small RNAs. At the same time, they reported that their discovery suggests the presence of a strikingly novel biochemical pathway for RNA processing in which these and possibl...

Networks of small habitat patches can preserve urban biodiversity

Sets of small and seemingly insignificant habitat patches that are within reach for mobile species may under certain circumstances, as a group, provide an acceptable alternative to larger and contiguous habitats. This finding can make preservation of important ecological functions possible even in...

Studies of small water fleas help ecologists understand population dynamics

(Santa Barbara, Calif.) A study of populations of tiny water fleas is helping ecologists to understand population dynamics, which may lead to predictions about the ecological consequences of environmental change. The study is published in today's issue of the journal Nature . The water flea, ...

When particles are so small that they seep right through skin

Scientists are finding that particles that are barely there tiny objects known as nanoparticles that have found a home in electronics, food containers, sunscreens, and a variety of applications can breech our most personal protective barrier: The skin. The particles under scrutiny by Lisa DeL...

Exciting new companies at NJIT's small biz incubator get 100K in grants

The New Jersey Commission on Science and Technology has awarded almost $100,000 as part of its SBIR bridge grant program to two start-up companies based in NJIT's high technology business incubator. Applechem Inc. www.applechem.biz and Lenterra www.lenterra.com , located in NJIT's Enterprise ...

Exciting new companies at NJIT's small biz incubator get 100K in lrants

The New Jersey Commission on Science and Technology has awarded almost $100,000 as part of its SBIR bridge grant program to two start-up companies based in NJIT's high technology business incubator. Applechem Inc. www.applechem.biz and Lenterra www.lenterra.com , located in NJIT's Enterprise ...

High blood pressure takes big toll on small filtering units of the kidney

Take a kidney out of the body and it still knows how to filter toxins from the blood. But all bets are off in the face of high blood pressure. "How does the kidney know how to do it and why does it break in hypertension?" says Dr. Edward W. Inscho, physiologist in the Medical College of Geor...

In spiders, size matters: Small males are more often meals

Female spiders are voracious predators and consume a wide range of prey, which sometimes includes their mates. A number of hypotheses have been proposed for why females eat males before or after mating. Researchers Shawn Wilder and Ann Rypstra from Miami University in Ohio found, in a study publis...

Photos reveal Myanmar's large and small predators

NEW YORK (September 4, 2008)Using remote camera traps to lift the veil on Myanmar's dense northern wild lands, researchers from the Wildlife Conservation Society have painstakingly gathered a bank of valuable data on the country's populations of tigers and other smaller, lesser known carnivores (s...

Pay attention! Small packages may lead to overeating

Tempting treats are being offered in small package sizes these days, presumably to help consumers reduce portion sizes. Yet new research in the Journal of Consumer Research found that people actually consume more high-calorie snacks when they are in small packages than large ones. And smaller pa...

Crop management: How small do we go?

MADISON, WI, JULY 7, 2008 -- The use of on-the-go crop and soil sensors has greatly increased the precision with which farmers can manage their crops. Recently released research in Agronomy Journal questions whether more precise management is necessarily more efficient. They discovered that the ...

Automated microfluidic device reduces time to screen small organisms for genetic studies

Genetic studies on small organisms such as worms and flies can now be done more quickly using a new microfluidic device developed by engineers at the Georgia Institute of Technology. The new "lab-on-a-chip" can automatically position, image, determine the phenotype of and sort small animals, su...

Genome sequence of small marine creature sheds light on vertebrate origins

Genome Research is publishing several papers related to analyses of the amphioxus ( Branchiostoma floridae ) genome sequence. The amphioxus, or lancelet, is a cephalochordate residing in shallow regions of tropical and temperate seas, bearing resemblance to a small fish, however lacking pairs o...

Plant biologists discover unexpected proteins affecting small RNAs

LA JOLLA, CA - Now that high school biology students can recite that genes are made of DNA, which is transcribed into messenger RNA (mRNA), which is then translated into protein, along comes a new class of molecules, sending studentsand many scientistsscrambling for updated textbooks. A study b...

Scientists discover small RNAs that regulate gene expression and protect the genome

RNA is best known as a working copy of the DNA sequence of genes. In this role, its a carrier of the genes instructions to the cell, which manufactures proteins according to information in the RNA molecule. But molecular biologists have increasingly realized that many RNA snippets -- so-called...

1/3 of risk for dementia attributable to small vessel disease, autopsy study shows

Alzheimer's disease may be what most people fear as they grow older, but autopsy data from a long-range study of 3,400 men and women in the Seattle region found that the brains of a third of those who had become demented before death showed evidence of small vessel damage: the type of small, cumul...

Pioneers in small RNA research to present at UD symposium, April 16

Three of the world's pioneers in small RNA research--Victor Ambros, Gary Ruvkun and David Baulcombe--will lecture on their recent discoveries at a special half-day symposium at the University of Delaware from 9 a.m. to 12:30 p.m., Wednesday, April 16, in the Gore Recital Hall of the Roselle Center...

Research team finds that microorganisms filter nitrogen from small streams

MANHATTAN, KAN. -- To understand how nitrogen accumulates in large rivers and oceans miles and miles away, scientists like Walter Dodds looked at small streams flowing closer to home. Dodds, a professor of biology at Kansas State University, didn't have to look any farther than his own campus f...

Identification of a novel class of (not-so) small RNAs

In the December 1st issue of G&D, Dr. Hailing Jin and colleagues (UC Riverside) report on their discovery of a new class of small RNAs in Arabidopsis. These newly-discovered, 30-40 nt long small RNAs have been dubbed long short interfering RNAs (lsiRNAs), and are induced by bacterial infection or ...

Sweet potato shines as new promise for small enterprise and hunger relief in developing countries

WASHINGTON, DC -- Sweetpotatoes, often misunderstood and underrated, are receiving new attention as a life-saving food crop in developing countries. According to the International Potato Center ( www.cipotato.org ), more than 95 percent of the global sweetpotato crop is grown in developing coun...

Cilia: small organelles, big decisions

Johns Hopkins researchers say they have figured out how human and all animal cells tune in to a key signal, one that literally transmits the instructions that shape their final bodies. It turns out the cells assemble their own little radio antenna on their surfaces to help them relay the proper si...

Handbook of small grain insects available now

The Entomological Society of America (ESA), in cooperation with the American Phytopathological Society (APS), announces the publication of Handbook of Small Grain Insects, the latest in ESAs Insect Pest Handbooks series. This comprehensive color guide examines the biology and management of arthrop...

Predicting the distribution of creatures great and small

In studying how animals change size as they evolve, biologists have unearthed several interesting patterns. For instance, most species are small, but the largest members of a taxonomic group -- such as the great white shark, the Komodo dragon, or the African elephant are often thousands or millio...

Study shows big power of small RNAs, not just proteins, in halting cancer

Cold Spring Harbor, N.Y. – Cold Spring Harbor Laboratory (CSHL) researchers led by Lin He, Xingyue He, and Professor and Howard Hughes Medical Investigator (HHMI) Greg Hannon have identified a family of micro RNAs (miRNAs) that enable a critical tumor suppressor network, called the p53 pathway, to...

Why doesn't the immune system attack the small intestine?

Answering one of the oldest questions in human physiology, researchers at Dana-Farber Cancer Institute have discovered why the body's immune system - perpetually on guard against foreign microbes like bacteria ?doesn't attack tissues in the small intestine that harbor millions of bacteria cells. ...

'Juiced-up' battery fueled by sugar could power small portable electronics

Dutch researcher Harm Veling has demonstrated that our brains fend off distractions. If we are busy with something we suppress disrupting external influences. If we are tired, we can no longer do this. Social-psychologist Veling proved that the brain selects incoming information to remember usef...

Bacteria in small sea life yield new way to make potential cancer drugs

Researchers led by a University of Utah medicinal chemist have developed a novel method to make drugs for cancer and other diseases from bacteria found in sponges and other small ocean creatures. In a study published Sunday, Nov. 5, in Nature Chemical Biology online, researchers examined symbiot...

Study suggests that publicly available genome data may contain small but significant errors

Since the genome sequence of the bacterial pathogen Haemophilus influenzae was published in 1995, the genetic code of many other large, complex, medically, and commercially significant organisms including humans has also been elucidated. However, the techniques used to derive these genetic sequen...

Next good dinosaur news likely to come from small packages

Dinosaurs seem bigger than life ?big bones, big mysteries. So it's a delicious irony that the next big answers about dinosaurs may come from small ?very small ?remains. "Molecules are fossils, too," said Michigan State University zoologist Peggy Ostrom. "We've shown that proteins survive in very...

One small step means giant leap for spinal cord research

A new device developed at the University of Toronto that stimulates the muscles of patients with spinal cord injuries helps to increase walking function in those whose condition is not expected to improve. U of T researchers have found that functional electrical stimulation (FES), a process that...

Scientists learn to predict protein-stabilizing ability of small molecules

Prostate cancer is the second leading cause of death among American men. It is estimated that one in six males will develop the disease during his lifetime. However, promising new treatment options have been developed to help combat this threatening disease. One of the most innovat...

Delaware scientists make significant advance in study of small RNAs

Scientists from the University of Delaware have made a significant advance in the study of small ribonucleic acids (RNAs), discovering 10 times more small RNAs in the plant Arabidopsis than previously had been identified. The advance is reported in the Sept. 2 issue of Science magazine. The resea...

Solexa and collaborating scientists illuminate the small RNA component of the transcriptome

Solexa, Inc. (Nasdaq: SLXA) today announced that its researchers in collaboration with the Delaware Biotechnology Institute and the University of Delaware reported the most comprehensive analysis to date of the small RNA component of the transcriptome. The research, "Elucidation of the Small RNA Co...

No small feat: First ever gene therapy success for muscular dystrophy achieved

Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children w...

Circulating stem cells play small role in lung repair

Circulating stem cells play a minor role in repairing lung damage, according to a team of scientists who used male and female chromosomal differences to analyze the repair process in lung transplant patients. Reporting in today's edition of the journal Transplantation, lead author Dani Zander, M....

New World founders small in number

About 14,000 years ago - a few hundred thousand years after our putative modern forebears spread out from Africa - descendants of archaic humans crossed the Bering land bridge from Siberia to North America. Several lines of evidence support this model, but that's where the consensus ends and the de...
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