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Sequencing in Biological News

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

The Human Microbiome Project has awarded more than $42 million to expand its exploration of how the trillions of microscopic organisms that live in or on our bodies affect our health, the National Institutes of Health (NIH) announced today. The human microbiome is all the microorganisms that...

Stowers researchers develop whole genome sequencing approach for mutation discovery

The Stowers Institute's Hawley Lab and Molecular Biology Facility have developed a "whole-genome sequencing approach" to mapping mutations in fruit flies. The novel methodology promises to reduce the time and effort required to identify mutations of biological interest. The work was published in t...

MCTP bought Genomatix NextGen Sequencing analysis stations

Ann Arbor, MI and Munich (Germany) March 26, 2009 - Genomatix Software, a leading provider of complete solutions for the analysis of Next Generation Sequencing (NGS) data, announced today that the Michigan Center for Translational Pathology (MCTP) at the University of Michigan installed a Genomat...

CRG buys Genomatix' Next Generation Sequencing analysis solution

The Centre for Genomic Regulation (CRG) in Barcelona, Spain purchased the Genomatix Genome Analyzer (GGA), as announced today by Genomatix Software GmbH. GGA comprises purpose built high performance hardware and terabytes of proprietary databases and software providing a complete solution for th...

Boehringer Ingelheim uses Genomatix' Next Generation Sequencing data analysis systems

Munich, Germany March 2, 2009 >> Genomatix Software, a leading provider of complete solutions for the analysis of Next Generation Sequencing (NGS) data, announced today that Boehringer Ingelheim Pharma GmbH & Co. KG installed a Genomatix Mining Station and a Genomatix Genome Analyzer at its Pharm...

Genome sequencing of fungus with biotechnological applications

Researchers Antonio G. Pisabarro (Professor of Microbiology) as well as Jos Luis Lavn and Jos Antonio Oguiza, from the Genetic and Microbiology Group at the Public University of Navarre, have taken part in the international project for the sequencing of the genome of the Postia placenta fungus. ...

Complete Genomics releases proof-of-concept data for its sequencing technology for the first time

MOUNTAIN VIEW, Calif. Feb. 6, 2009 Complete Genomics, Inc. released proof-of-concept (PoC) data for its human genome sequencing technology for the first time yesterday evening. The analysis results were reviewed by Dr. Clifford Reid, Complete Genomics chairman, president and CEO, during his pres...

UC San Diego and Genentech scientists develop potentially disruptive antibody sequencing technology

Bioinformatics researchers at the University of California, San Diego and Genentech have developed a new, quicker way to sequence monoclonal antibodies a process that is many times faster than the sequencing technology typically used by academic and industry researchers today. The breakthroug...

Complete Genomics launches, becomes world's first large-scale human genome sequencing company

MOUNTAIN VIEW, Calif. Oct. 6, 2008 Complete Genomics Inc., a third-generation human genome sequencing company, today announced its formal launch as the world's first provider of large-scale human genome sequencing services. The company, which was established in March 2006, has been operating...

NHGRI seeks DNA sequencing technologies fit for routine laboratory and medical use

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today awarded more than $20 million in grants to develop innovative sequencing technologies inexpensive and efficient enough to sequence a person's DNA as a routine part of biomedical research an...

UI and ISU establish shared DNA sequencing instrumentation

AMES and IOWA CITY, Iowa The University of Iowa and Iowa State University are pooling their resources to significantly enhance both institutions' genetic research capabilities. The two institutions have each purchased a massively parallel DNA sequencer an instrument capable of deciphering DNA...

Deep sequencing study reveals new insights into human transcriptome

In a collaborative project scientists from the Max-Planck-Institute for Molecular Genetics in Berlin (MPI MolGen), Germany and Genomatix with a business in Munich, Germany and Ann Arbor, MI, USA, applied next generation sequencing and analysis methods to generate an unprecedented view at the human...

Duckweed genome sequencing has global implications

NEW BRUNSWICK, N.J. Three plant biologists at Rutgers' Waksman Institute of Microbiology are obsessed with duckweed, a tiny aquatic plant with an unassuming name. Now they have convinced the federal government to focus its attention on duckweed's tremendous potential for cleaning up pollution, ...

US Department of Energy Joint Genome Institute announces new genome sequencing projects

WALNUT CREEK, CAIn the continuing effort to tap the vast, unexplored reaches of the earth's microbial and plant domains for bioenergy and environmental applications, the DOE Joint Genome Institute (DOE JGI) has announced its latest portfolio of DNA sequencing projects that it will undertake in the...

Argonne-University of Chicago joint venture bolsters genomic sequencing capabilities

ARGONNE, Ill. (June 9, 2008) The Institute for Genomics and Systems Biology (IGSB), a joint venture of the U.S. Department of Energy's (DOE) Argonne National Laboratory and the University of Chicago, has acquired two new instruments that provide an enhanced ability to sequence genomes more quickl...

Genetic sequencing of protein from T. rex bone confirms dinosaurs' link to birds

Scientists have put more meat on the theory that dinosaurs' closest living relatives are modern-day birds. Molecular analysis, or genetic sequencing, of a 68-million-year-old Tyrannosaurus rex protein from the dinosaur's femur confirms that T. rex shares a common ancestry with chickens, ostrich...

Beijing Genomics Institute adds AB SOLiD system to its next generation sequencing technologies

The Beijing Genomics Institute announced today that BGI has added Applied Biosystems SOLiD System to BGI's rapidly expanding next-generation sequencing technologies. Two AB SOLiD Systems have been installed and were thoroughly tested by the BGI researchers. The AB SOLiD System generated high-th...

K-State contributions to red flour beetle genome sequencing featured in March 27 issue of Nature

MANHATTAN, KAN. -- Most of us hate to find the red flour beetle living happily in the flour sack in our pantries. But for several scientists at Kansas State University, and many others throughout the world, this pest of stored grain and grain products is the best organism for studying genetics. ...

DOE JGI Community Sequencing Program delivers first moss genome

WALNUT CREEK, CAMessages from nearly a half-billion years ago, conveyed via the inventory of genes sequenced from a present-day moss, provide clues about the earliest colonization of dry land by plants. The U.S. Department of Energy Joint Genome Institute (DOE JGI) was among the leaders of an int...

454 Sequencing: Science paper describes a novel, highly efficient method of sequencing ancient DNA

Branford, September 27, 2007 454 Life Sciences, a Roche company, today reported that researchers from Pennsylvania State University have used the companys Genome Sequencer FLX system to sequence the entire mitochondrial genomes from 10 individual woolly mammoths. The study, entitled "Whole-Geno...

454 Sequencing uncovers a genetic basis for different social behaviors in wasp

Branford, September 27, 2007 454 Life Sciences, a Roche company, in collaboration with researchers from the University of Illinois at Urbana-Champaign today announced that they have uncovered genetic underpinnings to social behavior in wasps. Using the companys Genome Sequencer system, the rese...

New technique could dramatically lower costs of DNA sequencing

CHAMPAIGN, Ill. Using computer simulations, researchers at the University of Illinois have demonstrated a strategy for sequencing DNA by driving the molecule back and forth through a nanopore capacitor in a semiconductor chip. The technique could lead to a device that would read human genomes qui...

UC Irvine receives $2.18M to explore nano advancements in DNA sequencing

Irvine, Calif., Oct. 1, 2007 UC Irvines Henry Samueli School of Engineering has been awarded $2.18 million to blend traditional DNA sequencing techniques with cutting-edge nanotechnology to develop a faster and less costly method of analysis. The goal is to make DNA sequencing feasible as a routi...

454 sequencing identifies HIV drug resistance at early stage

454 Life Sciences, a member of the Roche group, and a Yale School of Medicine researcher today announced that they have used the company’s Genome Sequencer™ system to identify previously undetectable rare drug resistant HIV variants in samples from an earlier performed clinical trial. The work, p...

Genome sequencing reveals key to viable ethanol production

As the national push for alternative energy sources heats up, researchers at the University of Rochester have for the first time identified how genes responsible for biomass breakdown are turned on in a microorganism that produces valuable ethanol from materials like grass and cornstalks. Waste p...

Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting

Four hundred researchers tapping the massive flow of DNA sequence information will gather March 28-30 to share their recent developments at the 2nd Annual U.S. Department of Energy Joint Genome Institute (DOE JGI) User Meeting. DOE JGI is the world's only user facility dedicated to making high-thro...

Faster, low cost sequencing technologies needed to drive era of personalized medicine

DNA testing is transforming health care and medicine, but current technologies only give a snapshot of an individual's genetic makeup. Any patient wanting a complete picture of their inherited DNA, or genome, would drop their jaw at the sight of the bill -- to the current tune of $10 million or mor...

NHGRI aims to make DNA sequencing faster, more cost effective

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today announced the latest round of grant awards totaling more than $13 million to speed the development of innovative sequencing technologies that reduce the cost of DNA sequencing and expand the...

Scientists win grants to develop $1,000 genome sequencing technology

The current cost to determine the sequence of nucleotide bases in the 6-billion-base-pair human genome is roughly $10 million, but researchers at UC San Diego and eight other universities and biotech companies hope to use a federal grant to lower the cost to only $1,000 per human genome sequenced. ...

Columbia University licenses next-generation DNA sequencing technology

Columbia University announces today that it recently executed an exclusive license agreement for a next generation DNA sequencing technology to Intelligent Bio-Systems (IBS), Inc. This innovative DNA-sequencing technology was invented by Dr. Jingyue Ju, professor of Chemical Engineering and head of...

NHGRI announces latest sequencing targets

The National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), today announced several new sequencing targets including the Northern white-cheeked gibbon (Nomascus leucogenys), setting the stage for completing a quest to sequence the genome of at least one non...

Mitochondrial DNA sequencing tool updated

High-tech laboratory tools, like computers, are often updated publicly as their analytical capabilities expand. In the September issue of the Journal of Molecular Diagnostics, NIH grantees report they have developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that for the ...

NHGRI announces new sequencing targets

The National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), today announced its latest round of sequencing targets, with an emphasis on enhancing the understanding of how human genes function and how genomic differences between individuals influence the ris...

Genome sequencing is for ecologists, too

An organism widely used for genetics-versus-environment studies has joined the panoply of mice, rats, dogs, humans and other species whose entire genomes have been sequenced. At the Daphnia Genomics Consortium's annual meeting in Bloomington this week, Indiana University and Joint Genome Institut...

Detection of DNA on nanotubes offers new sensing, sequencing technologies

Researchers at the University of Illinois at Urbana-Champaign who recently reported that DNA-wrapped carbon nanotubes could serve as sensors in living cells now say the tiny tubes can be used to target specific DNA sequences. Potential applications for the new sensors range from rapid detection of ...

NHGRI expands effort to revolutionize sequencing technologies

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today announced it has awarded grants totaling more than $32 million to advance the development of innovative sequencing technologies intended to reduce the cost of DNA sequencing and expand the u...

Gene sequencing explains bioremediation 'bug'

A team led by Johns Hopkins scientists has found the first clear evidence that the process behind the human immune system's remarkable ability to recognize and respond to a million different proteins might have originated from a family of genes whose only apparent function is to jump around in gene...

Understanding how weeds are resistant to herbicides

...porated into a growing DNA strand. "The reason it's so fast is that it's done in parallel," said Tranel. "The plate has thousands of tiny wells, and a sequencing reaction going on in every one of them simultaneously. There's a camera that monitors the light for each of these wells simultaneously and so in one s...

Obama administration announces more than $327 million in Recovery Act funding for science research

... the world's most advanced centers for fundamental research on biofuels; New equipment for DOE Joint Genome Institute, the world's largest genomic sequencing facility for non-medical, DOE mission-related research in bioenergy, climate, and environmental remediation; Improvements at high-intensity light...

Scientists decoding genomic sequences of H1N1 using isolates from outbreak in Argentina

...ecimens from nasopharyngeal swabs and cultures over the next 10 days, and will share their findings with the larger scientific community. The complete sequencing of these virus specimens will allow the team to both characterize severe versus mild cases, as well as determine how the virus evolved at different po...
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