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Cyanobacterium sequenced features rare linear chromosome

A team of researchers headed by biologists at Washington University in St. Louis has sequenced the genome of a unique bacterium that manages two disparate operations photosynthesis and nitrogen fixation in one little cell during two distinct cycles daily. Himadri B. Pakrasi, Ph.D., George Wi...

Trichoplax genome sequenced -- 'rosetta stone' for understanding evolution

New Haven, Conn. Yale molecular and evolutionary biologists in collaboration with Department of Energy scientists produced the full genome sequence of Trichoplax , one of nature's most primitive multicellular organisms, providing a new insight into the evolution of all higher animals. The find...

The beetle's genome sequenced for the first time

75% of all animal species in the world are insects. The largest group within insects are beetles (400,000 species). Beetles can be very beautiful and colorful, but many beetle species are also serious agricultural pests that can destroy food plants like potatoes (the Colorado potato beetle) and th...

Bacterium sequenced makes rare form of chlorophyll

Researchers at Washington University in St. Louis and Arizona State University have sequenced the genome of a rare bacterium that harvests light energy by making an even rarer form of chlorophyll, chlorophyll d. Chlorophyll d absorbs red edge, near infrared, long wave length light, invisible to th...

Giant panda genome to be sequenced

BGI-Shenzhen is pleased to announce the launch of the International Giant Panda Genome Project. This announcement follows on the heels of the Panda Genome workshop held on January 2122, 2008, in Shenzhen, China. Dr. Hongmei Zhu, a scientist from BGI-Shenzhen, stated that, "The goal of this project...

Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex

In a venture once thought to lie outside the reach of science, researchers from Harvard Medical School and Beth Israel Deaconess Medical Center have captured and sequenced tiny pieces of collagen protein from a 68 million-year-old Tyrannosaurus rex. The protein fragments—seven in all—appear to most...

A salty tale: New bacterial genome sequenced from ancient salterns

Tourists in Spain often stop to ogle the country's many saltwater lagoons, used to produce salt since Roman times. Scientists, too, admire these saltern crystallizers--and even more so, the microbes that manage to survive in such briny environs. Now, reporting in the November 28-December 2 early on...

Understanding how weeds are resistant to herbicides

...e able to start generating data now that five years ago would have been cost-prohibitive." Tranel believes waterhemp is the first weed to be partially sequenced using this technology. The pyrosequencing machine emits a light signal that's captured every time a nucleotide is incorporated into a growing DNA st...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

...lthough the gene for PGL2 had not been identified, we knew that it was located on the same chromosome as the hSDH5 gene." Rutter and his colleagues sequenced the hSDH5 gene in three individuals with PGL2 from a previously described Dutch lineage. They identified a single DNA nucleotide change which resulted...

Reviews of microbial gene language published in special issue of Trends in Microbiology

...dy Torto-Alalibo, who coordinates the PAMGO project, remarked: "Advances in sequencing technologies have led to a remarkable increase in the number of sequenced microbial genomes. Analysis of these genomes has provided useful information about genes that may be important in microbe-host interactions. However r...

Exploring standards to advance microbial genomics

...advancement of the field. Although nearly 1,000 microbial genomes have been sequenced over the past 15 years, nearly a quarter of them by DOE JGI, he noted that ...resents the group. Taking this one step farther, all the genes from all the sequenced strains in a species the pan-genome for that species would constitute the...

CSHL scientists harness logic of 'Sudoku' math puzzle to vastly enhance genome-sequencing capability

...oaches that allowed only a single DNA sample to be sequenced at a time. It also significantly improves upon cur...mples gathered by Dor Yeshorim to be processed and sequenced in a single time-saving and cost-effective experim...nly short segments of an individual's genome to be sequenced to find out if the individual is carrying a certai...

The SIB recognizes the next generation of bioinformaticians

...on of intra- and interprotein interactions with greatly improved accuracy. Dr. Burger explains the importance of such a methodology, "As the number of sequenced genomes has grown exponentially over the last years, multiple alignments of many protein families now contain more than 100 homologous sequences(and s...

DOE JGI releases expanded version of Phytozome.net

... Phytozome now spans fourteen plant genomes, including eight that have been sequenced at the DOE JGI: Populus trichocarpa , the black cottonwood tree, the first tree sequenced and being explored as a feedstock for a new generation of cellulosic biofue...

DNA blueprint for healthier and more efficient cows

... Ground breaking findings by an international consortium of scientists who sequenced and analysed the bovine genome, could result in more sustainable food production. The findings, published in two reports in the journal Science t...

Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals

... Sciences. Drs. Zagon and McLaughlin discovered the growth related activity of endogenous opioids, identified OGF as the specific peptide, cloned and sequenced OGFr, and collaborated on demonstrating the remarkable properties of these native peptides in a variety of clinical studies. OGF has proven successfu...

The genetic X-factor

...n the X chromosome: males have only one X chromosome and so a gene mutation on the X is more likely to have an effect in males than in females. "We sequenced 720 out of the approximately 800 known genes on the X chromosome in more than 200 families affected by X-linked learning disabilities," explains Profe...

UC Riverside biochemist to study how crops can increase protein production

...ies as a model organism in plant biology. A member of the mustard family, Arabidopsis offers researchers several advantages such as a completely sequenced genome, a compact size, a life-cycle of about only six weeks from seed to seed, easy cultivation and high seed production. Now Daniel Gallie , a p...

Genes from tiny marine algae suggest unsuspected avenues for new research

.... Microbial oceanographer Alexandra Worden led a team of scientists that sequenced the genomes of two Prasinophytes in the genus Micromonas . Each Micromona...genomes of other green algae (at least not in the five or six other species sequenced to date). Some of these genes, however, are found in land plants or bacteri...

Genes from tiny algae shed light on big role managing carbon in world's oceans

...t comparative analysis with other algae previously sequenced by DOE JGI and Genoscope [France], have proven imm...ed group of green algae with the largest number of sequenced genomes. With these four genomes in hand--two Mic...ps a run for his money. Unlike other algae genera sequenced to date, these swift swimmers can cut through the ...

Rhythmic genomics -- the yeast metronome and the walk of life

...rved and allows us to track the evolutionary history of hybrids. Steve James, lead researcher at the Institute of Food Research (IFR), said "I have sequenced these genes to selectively identify yeast species for over 15 years and had no idea they would turn out to be so variable." Rob Davey, computationa...

To swim or to crawl: For the worm it's a no brainer

...le of individual genes may be more apparent." C. elegans , a tiny free-living worm, was the very first animal species to be completely genetically sequenced and operates with many of the same genes that are found in human beings. It is used by scientists as a model system to gain a fundamental understandin...

New technique used to profile anthrax genome

...eloped a set of procedures that can be used to apply RNA-Seq to any bacterium. In using this approach to study B. anthracis, Bergman and colleagues sequenced mRNA samples that were collected from B. anthracis cells growing in a variety of conditions. They collected more than 270 million sequence "tags," eac...

200,000 rice mutants available worldwide for scientific investigation

...esearchers as they continue their work. Dr. Andy Pereira, Professor at the Virginia Bioinformatics Institute, stated: "The Oryza sativa genome was sequenced in 2002 and researchers have come a long way since. Advances in technologies such as high-throughput sequencing and RNA interference gene silencing me...

200,000 rice mutants available worldwide for scientific investigation

...esearchers as they continue their work. Dr. Andy Pereira, Professor at the Virginia Bioinformatics Institute, stated: "The Oryza sativa genome was sequenced in 2002 and researchers have come a long way since. Advances in technologies such as high-throughput sequencing and RNA interference gene silencing me...

Boehringer Ingelheim uses Genomatix' Next Generation Sequencing data analysis systems

...ntial splice junctions, which allows for splice junction analysis and identification of new transcriptional units. For genomic re-sequencing and newly sequenced genomes, a de novo assembly will be provided. The Genomatix Genome Analyzer (GGA) delivers downstream software tools and databases for the deep bio...

Complete Genomics releases proof-of-concept data for its sequencing technology for the first time

...Marriott Beach Resort, Marco Island, Fla. Complete Genomics successfully sequenced a Caucasian HapMap sample (Coriell catalog # NA07022; cell line DNA), gener...This marks a major achievement for the team at Complete Genomics they have sequenced a human genome at a high quality and low cost, which surpassed expectations...

Comparative genomics reveals molecular evolution of Q fever pathogen

...ut large-scale generation of non-functional genes, a change that may be associated with a more pathogenic lifestyle." In the study, the researchers sequenced the genomes of three strains of the bacteria and made a four-way comparison of C. burnetii genomic sequences. Strain virulence was associated with a...

Genome of a heat and drought resistant cereal plant analyzed

... Furthermore, the comparison with the C3 plant rice - likewise completely sequenced gives us information about how these cereals became more divergent in the ... squeezing the DNA through a pressurized syringe. Finally the fragments are sequenced from both ends ans subsequentially the millions of small DNA fragments are ...

Genome sequence shows sorghum's immense potential

...ource, says a University of Georgia researcher who led a team that recently sequenced the plant's genome. "Sorghum's importance is enormous," said Andrew Pate...ool to blend desirable traits into more improved commercial plants. The sequenced sorghum genome is also being used to improve biofuel crops like sugarcane a...

Genomatix joins Illumina-Connect program

...ential splice junctions, which allows for splice junction analysis and identification of new transcriptional units.For genomic re-sequencing and newly sequenced genomes, a de novo assembly will be provided. The GGA delivers downstream software tools and databases for the deep biological analysis of genomic po...

Scientists identify bacteria that increase plant growth

...h are known as endophytic bacteria, and tested selected strains' abilities to increase poplar growth in a controlled greenhouse environment. They also sequenced the genes from four selected bacterial species and screened them for the production of plant-growth promoting enzymes, hormones, and other metabolic f...

Biologist enhances use of bioinformatic tools and achieves precision in genetic annotation

...human species, may produce illnesses such as Alzheimer, Parkinson's, muscular dystrophies, etc. There are currently 27 genomes of fungi that have been sequenced and, amongst of all these what has been done is to detect what the differences are in the genes of the OXPHOS route. They did something similar as in ...

Study: Excessive use of antiviral drugs could aid deadly flu

...ide cooperation in data sharing is still a work in progress."Not all viruses that are isolated are sequenced, and not all viral genomes that have been sequenced are shared," he said.With this publication, Janies and colleagues have done some sharing of their own, establishing a service for other researchers at...

Snails and humans use same genes to tell right from left

...of the marine limpet Lottia gigantea, a right-handed snail whose genome was sequenced recently by the Department of Energy's Joint Genome Institute (JGI) in Waln...ound analogs of nodal in the genome of the marine worm Capitella, which was sequenced by JGI, suggesting that nodal is active throughout the Lophotrochozoa. "...

Breast cancer genome shows evolution, instability of cancer

...tell us how to best treat that cancer," said Dr. C. Kent Osborne, director of the Smith Breast Center and the Duncan Cancer Center. The researchers sequenced the MCF-7 breast cancer cell line, which is commonly used in studies of the disease. This study of the genome sequence refined the understanding of ab...

Dwarf crocodiles split into three species

...on. Dwarf crocodiles are listed as vulnerable on the International Union for Conservation of Nature's Red List. In the laboratory, the researchers sequenced more than 4,000 base pairs of both mitochondrial and nuclear DNA from as many as 82 individuals sampled across Central and West Africa. The results co...

DOE Joint Genome Institute completes soybean genome

... one of the largest and most complex plant genomes sequenced by the whole genome shotgun strategy," noted Rokhs...nd nearly half-again as many as the poplar genome, sequenced by DOE JGI and published in the journal Science in...h as the water mold Phytophthora sojae, previously sequenced by DOE JGI, which causes stem and root rot of soyb...

Research consortium to sequence turkey genome

...rkey genome sequence will enable the integration of other turkey research tools and resources, such as genetic linkage and cytogenetic maps, expressed sequenced tags, predicted genes and proteins, regulatory regions, and other resources. It will also serve as a platform for development of future tools, such as...

Mysterious microbe may play important role in ocean ecology

...al sample can be concentrated to nearly pure levels using flow cytometry. The team harvested DNA from the concentrated sample of cyanobacteria and sequenced it using the Genome Sequencer FLX system from 454 Life Sciences. The company's new sequencing reagents and software produce extra-long "reads" of DNA,...
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