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Sensitivity in Biological News

Statement by Sandy Andelman, co-author of 'Drought sensitivity of the Amazon Rainforest'

Here is a statement from Dr. Sandy Andelman, co-author of the study titled "Drought Sensitivity of the Amazon Rainforest" and Vice-President of the TEAM Network at Conservation International: "With most of the climate change debate focusing on energy security and food security, this study empha...

Site used by sodium to control sensitivity of certain potassium ion channels

RICHMOND, Va. (Sept. 18, 2008) Virginia Commonwealth University School of Medicine researchers have uncovered how sodium is able to control specific potassium ion channels in cells, according to new study findings published online this week in Nature Chemical Biology . These findings, publish...

Trans-fatty acids and insulin sensitivity

Trans-fatty acids have been the topic of a lot of negative health news, but in the July Journal of Lipid research, a dietary study in rats suggests that trans-fats do not increase the risk of insulin resistance and diabetes, which may ease at least one area of concern. Epidemiological studie...

Moderate prenatal exposure to alcohol and stress in monkeys can cause touch sensitivity

A new study on monkeys has found that moderate exposure to alcohol and stress during pregnancy can lead to sensitivity to touch in the monkeys babies. In human children, sensitivity to touch is one of a number of characteristics of the approximately 5 percent of children who over-respond to senso...

Fruit fly study identifies gene mutation that regulates sensitivity to alcohol

Researchers at the University of California, San Francisco (UCSF) have discovered a gene mutation in fruit flies that alters sensitivity to alcohol. The findings, reported in the October 6 issue of the journal Cell, may have implications for human studies seeking to understand innate differences in...

Resistance and genetic sensitivity to sleeping sickness

Human African trypanosomiasis, more commonly called sleeping sickness, is induced by a parasite, the trypanosome, transmitted to humans by the bite of an insect, the glossinid tse-tse fly. There has been a resurgence of this disease over the past 20 years in Sub-Saharan Africa. The World Health Org...

Restoring tamoxifen sensitivity in resistant breast cancer cells

The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the Natio...

Increased sensitivity to nerve signals keeps diabetes at bay

Nerve signals relayed directly to the pancreas after eating a meal play a critical role in normal blood sugar control, according to a report in the June 7, 2006, Cell Metabolism. Therefore, drugs that increase the sensitivity to such signals might offer a new approach to diabetes treatment, the res...

Clock molecule's sensitivity to lithium sheds light on bipolar disorder

Researchers at the University of Pennsylvania School of Medicine discovered that a key receptor protein is a critical component of the internal molecular clock in mammals. What's more, this molecule –called Rev-erb?is sensitive to lithium and may help shed light on circadian rhythm disorders, inclu...

Mutations in the BRAF gene predict sensitivity to a novel class of cancer drugs

A team of researchers led by scientists at Memorial Sloan-Kettering Cancer Center have discovered that a new class of drugs -- now in early stage clinical trials -- work best in patients with mutations in the BRAF gene. BRAF is a protein that plays a central role in the growth and survival of cance...

Global warming increases oyster sensitivity to pollution

Do you enjoy eating oysters on a hot sunny afternoon? Make the most of it ?it may not last forever. Research has shown that global warming increases the sensitivity of oysters to metal pollution, causing a deadly threat to populations in polluted areas. Dr. Gisela Lannig from the University of Nort...

Assessing the Amazon River's sensitivity to deforestation

Understanding how the Amazon River varies in time, what causes those variations, and how sensitive it will be to ongoing, and accelerating, deforestation is a focus of study for scientists at the Woods Hole Research Center. Population and development pressures in the last several decades have led t...

Evolution of taste receptor may have shaped human sensitivity to toxic compounds

Researchers have found new evidence suggesting that the ability to taste bitter compounds has been strongly advantageous in human evolution. Animals rely on chemical perception, including the senses of taste and smell, for protection against the harmful compounds found in nature. It is widely bel...

Children's taste sensitivity and food choices influenced by taste gene

Variation in a taste receptor gene influences taste sensitivity of children and adults, accounting for individual differences in taste preferences and food selection, report a team of researchers from the Monell Chemical Senses Center. In addition to genes, age and culture also contribute to taste ...

DOE-funded research projects win 46 R&D 100 Awards for 2009

...chnologies, in Corvallis, OR. (Jointly with Perpetua) Ultrasensitive ESI-MS Source & Interface - integrates four technologies to provide greater sensitivity and precise measurements from mass spectrometry instrumentation while requiring smaller samples. Mass spectrometry instrumentation is commonly used f...

Munich researchers discover new target for tailored antibiotics

...sults, and for many years the crystal structure of the enzyme that would provide the proof could not be determined. The main problem was the oxygen sensitivity of the enzyme, which degenerates very quickly in air, thus losing both its structure and its function. Only recently a group from the Justus-Liebig Un...

Building memories with actin

...ssembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, 2009 iss... of LTP, and the Rac-PAK pathway solidifies them so that heightened synapse sensitivity can persist. The researchers hypothesize that one pathway encodes memories,...

Forest fire prevention efforts will lessen carbon sequestration, add to greenhouse warming

... reduction may still make more sense in east-side Cascade Range and other similar forests, but that the west-side Cascades and Coast Range have little sensitivity to forest fuel reduction treatments and might be best utilized for their high carbon sequestration capacities. "Ultimately, the real problem here ...

New biomarker method could increase the number of diagnostic tests for cancer

...te biomarker correspond with the presence or stage of a disease. A sophisticated type of mass spectrometry, MRM is designed for obtaining the maximum sensitivity for quantifying target compounds in patient samples. "Our work demonstrates that this technology has the potential to transform how candidate prote...

A urine test for appendicitis?

...ycoprotein (LRG), which appears to be a specific marker of local inflammation. It had an "area under the curve" value of 0.97, indicating near-perfect sensitivity (with almost no false-negatives) and near-perfect specificity (almost no false-positives). LRG was strongly elevated in diseased appendices, even when...

Caltech researchers explore how cells reconcile mixed messages in decisions about growth

...d his colleagues studied the interplay between contact inhibition and EGF in groups of epithelial cells, they found that the cells have a threshold of sensitivity to EGF. If EGF levels dip below the threshold, contact inhibition takes hold and puts the brakes on cell division. But if EGF levels rise above the th...

Size did matter

..."Holotomography is a non-destructive imaging technique like computer tomography (CT), but we use powerful and coherent synchrotron X-rays leading to a sensitivity thousand times higher," explains Paul Tafforeau of ESRF. "It is since very recently that palaeontologists use this technique to image fossils, but the...

Colon cancer screening technique shows continued promise in new study

...thwestern University researchers has a high enough sensitivity that it could potentially be as or more successful...ts showed that for advanced polyps, the test had a sensitivity of 100 percent, which means that 100 percent of pa...g healthy samples from diseased samples. While the sensitivity and specificity of tests may vary based on the thr...

Simple drug treatment may prevent nicotine-induced SIDS: Study

...xygen deprivation, therefore reversing the lethality of hypoxia. "Our initial goal was really to understand how the nervous system regulates oxygen sensitivity of cells in the adrenal gland at a basic research level," says Colin Nurse, academic advisor on the study and a professor in the department of Biology...

Design input accelerates new technologies' route to market

... By joining spaces as opposed to individuals ad-hoc interactions can be supported as well as pre-organised meetings. A potential increase in food sensitivity and allergy in the population requires improved tests so that conditions can be detected and managed. Dr Marcus Alcocer of the School of Biosciences i...

A quicker, cheaper SARS virus detector -- one easily customizable for other targets

...lating native oxide layer that can reduce sensitivity." The result, according to the paper, is a device that can detect its target molecules with a sensitivity as great as the best alternative modes, do so more rapidly and without use of chemical reagents. It is also potentially considerably cheaper than a...

Healing wounds with lasers, vehicles that drive themselves, other cutting-edge optics

...ownian motion") brought about by thermal energy. H. Jeff Kimble of Caltech will describe a new effort to counteract thermal noise and improve the sensitivity of interferometers. He and his colleagues argue that a very slight thermally-induced movement of a mirror's surface owing to thermal noise is accompan...

Investigating the development of mechanosensitivity

...itivity. At the same time they were able to show that neurons develop their sensitivity to touch and pain during different developmental phases but always coincide...ain signals to the brain. Very little, however, is known about how stimulus sensitivity actually emerges. Using the patch-clamp technique in isolated cells of ...

Skip this cocktail party

...with Frances Gulland, director of the Marine Mammal Center in Sausalito, CA, to examine how California sea lions's exposure to PCBs may increase their sensitivity to domoic acid, a naturally produced marine neurotoxin associated with "red tides." The work of Montie and his colleagues lays the groundwork for ...

Cocaine: Perceived as a reward by the brain?

...ll do not fully understand its mechanism of action. Is it the repeated stimulation of the reward circuit that leads to addiction, or is it an inherent sensitivity to addiction that leads to the increased secretion of dopamine? This question is not easy to answer, especially since other factors come into play, su...

MIT reels in RNA surprise with microbial ocean catch

...icals or pressure and modify their protein expression accordingly. But that sensitivity creates a quandary for the scientists who study them. Sort of like the obse... observer causes the microbes to change their protein expression. That same sensitivity makes some of these creatures exceedingly difficult to grow in lab cultures...

Does mom know when enough is enough?

...h that solid food was introduced, and the mothers' sensitivity to the infants' signals at 3 months were included....s, infant length gain from 3 to 6 months, maternal sensitivity to infant signals at 6 months, and the estimated n...ting weight gain from 6 to 12 months, and maternal sensitivity to the infants' signals reached predictive signifi...

Aerosol: A key piece of the climate change puzzle

...loited and the global aerosol model that has already been developed at Leeds (Global Model of Aerosol Processes). The Aerosol Model Robustness and sensitivity Study (AEROS) is a 3-year study funded by the Natural Environment Research Council in the UK. ...

Sugar, spice and puppy dog tails: Developing sex-typed personality traits and interests

...lly feminine, expressive traits didn't change over time. In contrast, boys' sensitivity and warmth declined substantially across middle childhood but increased in ...adolescence so that by about age 19, boys reported about the same levels of sensitivity and warmth as girls. For stereotypically masculine traits such as independe...

Joining forces to improve lung cancer treatment

...e III non-small-cell lung cancer (Poland) Confirmation that EGFR mutations (deletion in exon 19, missense L858R) are the most important predictors of sensitivity to tyrosine-kinase inhibitor targeted therapies (Italy) Barbara Zolty from the World Health Organization (WHO) will also highlight the importance ...

Vitamin D levels linked to asthma severity

... Rica, a country known to have a high prevalence of asthma. Each child was assessed for allergic markers, including both allergen-specific and general sensitivity tests, and assessed for lung function and circulating vitamin D levels. Children whose forced expiratory volume in one second (FEV1) exceeded 65 perce...

Drinking 100 percent fruit juice is associated with lower risk of obesity and metabolic syndrome

...EB) 2009 meeting highlights this association among adult men and women, with evidence showing that 100% juice drinkers were leaner, had better insulin sensitivity and had lower risk for obesity and metabolic syndrome a cluster of conditions that increases risk for stroke, heart disease and diabetes. Lookin...

Early isolation linked to enhanced response to cocaine

...ne, compared to male control and to female rats. Conclusions This study suggests that isolation during early development alters the brain sensitivity to cocaine, such that when the animal reaches adolescence and is exposed to cocaine, it is more sensitive to the psychostimulant effects of the drug. ...

Early isolation linked to enhanced response to cocaine

...ne, compared to male control and to female rats. Conclusions This study suggests that isolation during early development alters the brain sensitivity to cocaine, such that when the animal reaches adolescence and is exposed to cocaine, it is more sensitive to the psychostimulant effects of the drug. ...

Home tooth bleaching slightly reduces enamel strength

...n and tooth sensitivity. Azer said these side effects have been addressed by other products, such as toothpastes and treatment gels designed to lessen sensitivity and irritation. He and colleagues used extracted molars to assemble 65 human tooth samples measuring 4 millimeters square and 2 millimeters deep fo...
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