Screen in Biological News

SRI International to screen drugs that fight 2009 H1N1 influenza A

MENLO PARK, Calif. May 13, 2009 SRI International, an independent, nonprofit research and development organization, announced today that that it will screen a library of well-characterized drugs against the 2009 H1N1 influenza A virus, previously known as "swine flu." The work will be performed ...

Automated microfluidic device reduces time to screen small organisms for genetic studies

Genetic studies on small organisms such as worms and flies can now be done more quickly using a new microfluidic device developed by engineers at the Georgia Institute of Technology. The new "lab-on-a-chip" can automatically position, image, determine the phenotype of and sort small animals, su...

Cold Spring Harbor Protocols features methods to screen genomes and analyze evolution

COLD SPRING HARBOR, N.Y. (Tuesday, April 1, 2008) Identifying genes that are important in specific tissues or processes in the mouse used to be a monumental task. New technologies and strategies have simplified this search, making it effective for even the smallest laboratories. This months i...

Study suggests new way to screen infants for fetal alcohol syndrome

Cincinnati, OH, March 5, 2008 Children who have been diagnosed with Fetal Alcohol Syndrome (FAS) are more likely to have serious psychiatric and behavioral problems later in life, including a higher risk for dropping out of school, unemployment, and criminal behavior. Studies have shown that ear...

Fat screen delivers plant-derived chemical with antidiabetic effects

After screening hundreds of compounds for their effects on fat development, researchers have discovered that an ingredient found in some plants fights diabetes in mice without some of the side effects attributed to other antidiabetes drugs. The chemical they pinpointed, known as harmine, was first ...

Gene screen for breast cancer better than pathologist's 'eye'

Johns Hopkins scientists have found that a method they developed to screen body fluids for certain kinds of cells and some of their genetic blueprint is twice as accurate at spotting breast cancer cells as a pathologist's view with a microscope. The screen, developed by Sara Sukumar, Ph.D. and ...

Reducing risk of hospitalization in the elderly

... are much easier and cheaper to do, and are even more accurate in determining a person's risk of future hospitalization. This gives us the ability to screen larger groups of people and help those at risk with some simple interventions, such as physical exercise." ...

Results of national assessment of first responder location systems to be announced Aug. 3

...gear and fire trucks, and to provide information about the location of all firefighters and the paths they have taken on an easy-to-understand display screen at the command center. The WPI system also provides physiological monitoring of first responders via a sensor-equipped shirt developed by Foster Mille...

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

... technology and is currently working with Dr. Rubin, and his collaborator Dr. Arul Chinnaiyan at the University of Michigan, to develop urine tests to screen for gene fusions as a means of improving upon the current standard PSA test. Dr. Rubin, working in collaboration with Dr. Chinnaiyan's group at th...

$2 million grant aids study of lung cancer in people who never smoked

...sequencing the whole genome is going to be crucial, but we're still seeking additional funding for that." The ultimate goal is to develop a test to screen both nonsmokers and long-term former smokers before the onset of symptoms. "About 10 to 15 years after someone has stopped smoking, their cancer m...

New lab test offers better prediction of HIV microbicide safety

... namely, by disrupting the protective epithelial cell barrier," says Dr. Herold. "If confirmed by further study, this assay should be used early on to screen for microbicide safety before advancing a product to clinical trials involving thousands of women," she adds. Dr. Herold is also developing animal...

Clinical trial shows quadriplegics can operate powered wheelchair with tongue drive system

...n of the magnet with respect to the array of sensors in real-time. This information was then used to control the movements of the cursor on a computer screen or to substitute for the joystick function in a powered wheelchair. Details on use of the Tongue Drive for wheeled mobility were published in the June...

All in sight

... measurement method, infrared thermography, registers both at day and night the heat radiation originating from each body. It depicts it on a computer screen as a black and white picture, thus making it visible for humans: the brighter a spot, the warmer it is. The warm spout of a whale clearly stands out a...

Chromosomal problems affect nearly all human embryos

... Using new technologies that can detect chromosomal aberrations in the whole genome (all human chromosomes) of a single cell, the team was able to screen embryonic cells at a much higher resolution than previously, and hence identify more chromosomal abnormalities than has been possible using the curren...

New test can detect both genetic and chromosomal abnormalities in embryos

...d be possible to vitrify embryos at the blastocyst stage, either before or after biopsy, and analyse the embryos for virtually any genetic disease and screen for aneuploidy of all 23 pairs of chromosomes simultaneously. This approach could make PGD by karyomapping less expensive than conventional single dis...

New biomarker method could increase the number of diagnostic tests for cancer

...ifying protein biomarkers in body fluids may ultimately make it possible to screen multiple biomarkers in hundreds of patient samples, thus ensuring that only...in in a sample -- may be suitable for use in preclinical studies to rapidly screen large numbers of candidate protein biomarkers in the hundreds of patient sa...

Tryptophan deficiency may underlie quinine side effects

...rable on a cellular level and yeast is frequently, and successfully, used as front-line agents in testing chemicals and small molecule drugs. Their screen revealed that strains unable to make tryptophan were extremely susceptible to quinine poisoning, which led them to identify a tryptophan transporter a...

Trio of signals converge to induce liver and pancreas cell development in the embryo

...ution to fixing it, but it's a good place to start." In the near term, the team also aims to generate liver and pancreas cells for research and to screen drugs that repair defects or facilitate cell growth. ...

U of M study finds new insight on therapy for a devastating parasitic disease

...ntel caused a simple, striking effect: the drug subverts normal regeneration to produce two-headed organisms. This simple observation was then used to screen for genes required to control this effect, leading to the identification of molecules that control the effects of praziquantel within a flatworm model...

American Chemical Society's Weekly Presspac -- June 17, 2009

... plans to increasingly rely on so-called toxicity-based pathways to evaluate these substances. This approach involves using human cell cultures to screen newly marketed chemicals for adverse effects. The new tests will produce results in a fraction of the time now required with animal studies. But th...

Fate in fly sensory organ precursor cells could explain human immune disorder

...ensory organ precursor cell division has been used as a model to understand how Notch signaling is activated during asymmetric cell division. In a screen of fruit fly mutants that have disrupted peripheral nervous system development, Akhila Rajan and An-chi Tien, two graduate students in Bellen's labora...

Nanocrystals reveal activity within cells

...iving systems with minimal damage or light scatter. "Rare earths have been known to show phosphorescent behavior, like how the old-style television screen glows green after you shut it off. These nanocrystals draw on this property, and are a million times more efficient than traditional dyes," said Schuc...

Researchers from around the globe coming to K-State June 21 for workshop on Fusarium fungus

...much more efficient because strategies are more focused." The ability to screen for a particular species, or even a specific strain, of Fusarium offers m... "One of the big advances from our research is that the breeder can now can screen against the strains that they really care about," he said. "The first year ...

CSIRO deal to commercialize 'artificial gut'

...o help food manufacturers develop a wider range of healthy food products far more cheaply and quickly than possible previously. It can also be used to screen germplasm for functional grain attributes," Dr Lee said. "With the growing problem of obesity, diabetes and cardiovascular disease in Australia and ...

Slicing chromosomes leads to new insights into cell division

...therapy. "By knowing how chromosomes move, we can better understand how these drugs interfere with those movements and we can design experiments to screen for new drugs," Hunt said. "It will also allow us to have a better handle on what makes these drugs work. There are a lot of drugs that interfere with...

Stanford's Woods Institute awards new round of Environmental Venture Projects

...ecosystem service modeling, researchers will evaluate meadow restoration as an effective adaptation tool to combat climate change, develop a method to screen meadows as candidates for restoration and quantify changes in ecosystem services. PI: Steven Gorelick (Environmental Earth System Science). C...

Triage technology with a Star Trek twist

...ly diagnose obscure diseases. The standoff patient triage tool is a quantum leap forward for medical response, but science fiction remains on the big screen for the moment. The goal is to develop a handheld unit about the size of a legal notebook and as a thick as a ream of paper. Achieving this will req...

Healing wounds with lasers, vehicles that drive themselves, other cutting-edge optics

...anging vertical stripe of colors is swept across a screen faster than the eye can see, so spectators see the...ond to nanosecond timescales). What is seen on the screen of the scope is a waveform whose value is graphed ... swept horizontally providing a light-trace on the screen while, coincidentally, the instantaneous voltage o...

Identification of genetic variants affecting age at menopause could help improve fertility treatment

...ever, if these studies give us a better understanding of the function of the genetic variants involved in early menopause, we might one day be able to screen women who have problems getting pregnant to see if they have one or more of these variants which might relate to their sub-fertility, and perhaps inte...

Computer model predicts brain tumor growth and evolution

...to test if oxygen consumption rates influence tumor growth, the values assigned to those rates can be changed and the outcome observed on the computer screen not unlike playing a computer game. The result: A three-dimensional matrix of a glioma that can be adjusted to see what its growth stage will be over...

American Chemical Society's Weekly PressPac -- May 13, 2009

...ntify a substance based on its chemical fingerprint when exposed to specific kinds of light. In laboratory studies, the scientists used these tests to screen infant formula spiked with different concentrations of melamine. They found that these methods accurately detected the substance at levels as low as 1...

GenWay Biotech obtains exclusive rights to AMDL's DR-70 cancer test in US and Canada

...growing body of data reveals that the test is effective as a general cancer screen as well. The DR-70 ELISA assay quantifies Fibrin and Fibrinogen Degradatio... "The DR-70 cancer test can revolutionize the way people are able to easily screen their risk of cancer with a simple blood test. We are excited to play an i...

System that regulates blood pressure is amiss in some healthy, young blacks

...hat we are seeing yet we have some pathology here that could potentially explain difficult hypertension in kids," he says. One of his next steps is screen participants for a genetic mutation that has been linked to hypertensive kidney disease to see if that's a factor that can be used to help identify th...

NASA study says climate adds fuel to Asian wildfire emissions

...nts of Pollution in the Troposphere (MOPITT) instrument on NASA's Terra satellite -- as well as 1997-2006 fire data and research computer models -- to screen for and differentiate between carbon emissions from deforestation versus general emissions. Carbon monoxide is a good indicator of the occurrence of f...

Unifying the animate and the inanimate designs of nature

...sics to economics." He describes the law as an animated movie, where one screen is replaced by another screen on which the currents flow with greater ease. He sees the constructal law (...

Cystic fibrosis testing -- next steps

... reproductive-age population. Current professional guidelines call for screening a panel of 23 common mutations in CFTR ; however, many laboratories screen for an expanded panel of mutations. In the May 2009 issue of The Journal of Molecular Diagnostics , three articles describe improvements in cystic f...

Allscripts Integrates Electronic Health Records with Innovative Patient Kiosk

...e visits, including procedures undergone by the patient at that time. While accessing the patient's medical record, reminders can be sent to the kiosk screen for future annual exams and other periodic checkups. The Allscripts Patient Kiosk is available now through Allscripts, which provides physic...

Researchers use brain interface to post to Twitter

...motion on a computer screen. "We started thinking that moving a cursor on a screen is a good scientific exercise," says Justin Williams, a UW-Madison assistan...Williams. "And what your brain does is, if you're looking at the 'R' on the screen and all the other letters are flashing, nothing happens. But when the 'R' f...

The genetic X-factor

..., lead to learning disabilities. The international team studied almost all X chromosome genes in 208 families with learning disabilities - the largest screen of this type ever reported. Remarkably, the team also found that approximately 1𔃀% of X chromosome genes, when knocked-out, have no apparen...

2009 ASPB Summer Undergraduate Research Fellowship award announcement

...dopsis plant to Find New Components of ERECTA Signaling Pathway through EMS screen for Mutants This is a huge honor to be recognized by ASPB. I am looking ...tems. The project titled above is going to use a reverse 2-hybrid system to screen for mutated SAUR19 proteins that no longer interact with a known protein in...