Science

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

The National Library of Medicine, a part of the National Institutes of Health, is proud to present an extensive selection from the papers of one of the twentieth century’s greatest scientists, Francis Crick, on its Profiles in Science Web site. Don't miss Crick's This la...

Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis

Kinovate Life Sciences, Inc, a provider of tools for oligonucleotide synthesis and gene delivery, announced today that it will officially launch its new NittoPhase?solid support for oligonucleotide synthesis at the TIDES meeting commencing in Boston on May 1st. The joint development of this solid phase support product was announced on November 8th, 2004 by Kinovate’s sole shareholder, Nitto Denko...

Affymetrix Licenses Microfluidics Technology From Caliper Life Sciences

Caliper Life Sciences, Inc. (Nasdaq: CALP) and Affymetrix, Inc. (Nasdaq: AFFX) today announced that Caliper has issued Affymetrix a non-exclusive license to use a portion of Caliper's microfluidics patent estate with Affymetrix' GeneChip(R) microarray technologies. The license extends to the manufacture and sale of GeneChip brand products in all areas of application, including research, diagnosti...

What's really making you sick? Plant pathologists offer the science behind Sick Building Syndrome

Science-based identification of mold and other causes of Sick Building Syndrome may improve its management, say plant pathologists with The American Phytopathological Society (APS). Sick Building Syndrome (SBS) refers to a situation in which building occupants experience health problems while inside a particular building. Human health issues typically associated with SBS range from allerg...

Science study holds implications for gene therapy and stem cell biology

A study in the May 20 issue of Science holds mixed blessings for scientists who follow research in gene therapy and stem cell biology. The study, conducted by scientists from Cincinnati Children's Hospital Medical Center, and Hannover Medical School and Hamburg University in Germany, reveals important evidence that tells us more about how blood forming stem cells regenerate. On the other hand, sc...

Scientists generate patient-specific stem cells, Science study says

Scientists have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury. These ce...

Innovative collaboration brings Arctic science into the classroom

An upcoming expedition to study the Yukon and Mackenzie Rivers is not simply a research project for R. Max Holmes, an associate scientist at The Woods Hole Research Center. It is also a means to integrate education and outreach into his work. In June and July, Dr. Holmes, an ecosystem scientist with broad interests in the responses and feedbacks of ecosystems to environmental and global ch...

TrueBlue Archive Will Store Raw Life Sciences Data for Proteomics and Drug Testing

A new book, Biological Weapons Defense: Infectious Disease and Counterbioterrorism, deals with the intentional causality of disease. Published by Humana Press, this text is also available in e-Book. Many of the contributors come from the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), the nation's premier biodefense laboratory. In this 624-page, hardcover text edite...

Leprosy genome tells story of human migrations, French researchers report in Science

A French genetics study comparing strains of leprosy-causing bacteria has revealed some surprises about how the pathogen evolved and how it was spread across the continents by human migrations. The research, led by scientists at the Pasteur Institute in Paris, appears in the 13 May issue of the journal Science, published by AAAS, the nonprofit science society. The findings indicate that t...

DOE's Office of Science sets up program to aid scientists displaced by Hurricane Katrina

The Department of Energy's (DOE) Office of Science has established a program to assist scientists displaced by the effects of Hurricane Katrina. "Our colleagues in science have historically been a close-knit, generous community," wrote Dr. Raymond L. Orbach, director of DOE's Office of Science, in a letter describing the program to: universities and colleges, including those in Alabama, L...

Science's Breakthrough of the Year: Watching evolution in action

Evolution has been the foundation and guiding theory of biology since Darwin gave the theory its proper scientific debut in 1859. But Darwin probably never dreamed that researchers in 2005 would still be uncovering new details about the nuts and bolts of his theory -- how does evolution actually work in the world of influenza genes and chimpanzee genes and stickleback fish armor? Studies that fol...

Science captures the essence of fruit

New research designed to build scientific understanding of fruit genes could revolutionise the way foods, cosmetics and perfumes are created. Researchers at New Zealand-based life sciences company HortResearch say they have fine-tuned the science of gene discovery to such a degree that they can now accurately determine which genes create the individual flavours and fragrances found in fru...

Dalai Lama, top scientists to discuss science & clinical applications of meditation

Conference addresses western medicine & society's embrace of meditation, press meeting with Dalai Lama, Hopkins Medical Dean Edward Miller, and Georgetown University Professor Aviad Haramati at 8am on Nov. 8 With Western medicine's increasing interest in meditation's affect on mental and physical well-being, the Mind & Life Institute, in partnership with the Georgetown University M...

Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection

Sangamo BioSciences, Inc. today announced that data from its program to develop a ZFP Therapeutic for HIV/AIDS were presented at the 45th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Washington, DC. The study represents the first demonstration that cells can be made resistant to HIV infection by treatment with Sangamo's proprietary zinc finger DNA-binding pr...

'Creationism is not science' ?making the case for Darwin at UCL

Can the hold that Intelligent Design theorists have in America be broken by the evolutionists? Professor Michael Ruse, a leading American evolutionist, makes the case for Darwin in The Annual Robert Grant Lecture, "Darwin or Design? Reporting from the front lines of America's struggle over evolution", at the Grant Museum for Zoology at UCL (University College London) on 16th November. In h...

Are U.S. Flu Death Figures More PR Than Science?

Looking through his handmade microscope in 1702, it was Anton van Leeuwenhoek who first described the workings of a nano machine. He observed the rapid contraction of a stalk tethering the cell body of a tiny protozoan, Vorticella convallaria, to the surface of a leaf. Little did van Leeuwenhoek imagine that more than 300 years later, the biological spring that drives Vorticella would set records...

Scientist measures role of science's coolest player: The snow

What would the Earth be like if one fine day all the snow melted away? Obviously, it would be a much warmer place. But what's interesting is how much warmer, says Stephen Vavrus, an associate scientist at the Center for Climatic Research at the University of Wisconsin-Madison. Working with computer-generated simulations, Vavrus found that in the absence of snow cover, global temperatures w...

Study in Science holds promise for a new approach to drug therapy

Researchers believe they have found a way to change the action of 60 percent of currently available medications, in some cases making them many times more effective, according to an article published in the April 21 edition of the journal Science. The discovery has the potential to improve treatments for diseases including heart disease, cancer, diabetes, depression and arthritis. The study descr...

HortResearch science reveals the natural potential of apples

Fruit lovers worldwide may soon enjoy new, healthier, tastier apples, following the release this week of crucial genetic data which fruit breeders say will help revolutionise the produce industry. Researchers at New Zealand's world renowned fruit science company HortResearch, announced today that they would complete the public release of the world's most extensive collection of apple DNA s...

Science finds new fix for UV-damaged skin in arthritis treatment

For many women, accumulated sun exposure has already permanently damaged their skin cells, causing them to overproduce pigment that shows up as unsightly dark splotches and uneven skin tone over time. But new research indicates that glucosamine - a compound best known for treating arthritis ?can actually help stop the formation of new age spots, and help fade existing ones. "These findings...

The brain, traffic and nano-circuits -- e-Science takes on major challenges

Research into three major scientific and technological challenges is to receive a major boost from the application of e-Science and grid computing. The challenges are, understanding the brain, mapping the detailed environmental impact of traffic and designing future generation nano-scale electronic circuits. The Engineering and Physical Sciences Research Council (EPSRC) and other funding p...

PLoS ONE is launched by the Public Library of Science

Until now, online scientific journals have been little more than electronic versions of the printed copy. Today, that all changes with the launch of PLoS ONE, which publishes primary research from all areas of science and employs both pre- and post-publication peer review to maximize the impact of every report it publishes. PLoS ONE is published by the Public Library of Science (PLoS), the open a...

Cardiologist's 'living chip' changes science of disease monitoring

For patients living with heart failure and other health conditions, blood draws and diagnostic tests are commonplace in order to evaluate their condition. Often, though, chemical or physiologic changes silently cause damage that is not detected until much later. But what if in the future a tiny device, one the size of a nickel or significantly smaller, could be implanted in the patient to...

Public Library of Science to launch new, open access journal on neglected tropical diseases

The Public Library of Science (PLoS) announced today the creation of PLoS Neglected Tropical Diseases, the first open access journal devoted to the world's most neglected diseases. ) will focus on the overlooked diseases that strike millions of people every year in poor countries, including elephantias...

Scientist's persistence sheds light on marine science riddle

When he started compiling an online database of seashells 15 years ago, Dr. Gary Rosenberg did not envision that his meticulous record-keeping would eventually shed light on a 40-year-old evolutionary debate. The debate involves the mechanism underlying the island rule: that small animals isolated on islands evolve to be larger than their mainland relatives, and large animals evolve to be...

GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

For the first time, scientists have engineered yeast cells capable of producing a broad repertoire of recombinant therapeutic proteins with fully human sugar structures (glycosylation). These sugar structures ensure a glycoprotein's biological activity and half-life and to date, have necessitated the expression of therapeutic glycoproteins in mammalian hosts. The accomplishment reported today has...

Science researchers genetically transform immune cells into tumor fighters

A team of researchers has genetically engineered normal immune cells to become specialized tumor fighters, demonstrating for the first time that these engineered cells can persist in the body and shrink large tumors in humans. Two of the 17 people with advanced melanoma who received the experimental treatment saw their tumors shrink and were declared clinically free of disease more than...

NIH neuroscience microarray consortium launches high-throughput genotyping services

The NIH Neuroscience Microarray Consortium today announced that it has added high-density genotyping on both the Affymetrix and Illumina platforms to its list of services. Stan Nelson, the principal investigator at UCLA, says that "adding ultra-high throughput genotyping for its user-base of ~10,000 investigators across the world keeps the Consortium current with the demands of the scientific com...

New science of metagenomics 'will transform modern microbiology'

The emerging field of metagenomics, where the DNA of entire communities of microbes is studied simultaneously, presents the greatest opportunity -- perhaps since the invention of the microscope -- to revolutionize understanding of the microbial world, says a new report from the National Research Council. The report calls for a new Global Metagenomics Initiative to drive advances in the field in...

Are journal rankings distorting science?

This week’s BMJ raises concerns over whether journal rankings (known as impact factors) are distorting publishing and science. But a report by the BMJ this week warns that the popular...

Woman's Day and For Womens of Science

The health risks posed by mercury contaminated fish is sufficient to warrant issuing a worldwide general warning to the public ?especially children and women of childbearing age-to be careful about how much and which fish they eat. That is one of the key findings comprising "The Madison Declaration on Mercury Pollution" published today in a special issue of the international science journal Ambi...

Vitamins: Science doesn't always match policy

Some one hundred years after the first vitamin was named, what is known about them has not translated into beneficial, standardized recommendations for public health, says Irwin Rosenberg, MD, University Professor, and director of the Nutrition and Neurocognition Laboratory at the Jean Mayer USDA Human Nutrition Research on Aging (USDA HNRCA) at Tufts University. Based on his presentation at the...

Executable biology -- Computer science sheds light on animal development

By applying the techniques of computer engineering to a mechanistic diagram describing the development of the Nematode C. elegans, a group of researchers in Switzerland has been able to tease out what laboratory experiments have not ?how and when the crucial cross-talk between cellular signaling pathways takes place in order to determine the fates of individual cells. The novel in silico model is...

Sleepless for science: Flies show link between sleep, immune system in Stanford study

Go a few nights without enough sleep and you're more likely to get sick, but scientists have no real explanation for how sleep is related to the immune system. Now, researchers at the Stanford University School of Medicine are finding that fruit flies can point to the answers. What they have learned thus far is that illness and sleep disruption may be a two-way street: sick flies can't sle...

Researchers find 24 species believed new to science in Suriname rainforest

Presented in a report made public today, the findings from a 2005 expedition led by Conservation International’s Rapid Assessment Program (RAP) and a follow-up survey in 2006 demonstrat...