Study identifies trends of vitamin B6 status in US population sample
BOSTON- (May 20, 2008) In an epidemiological study, Tufts University researchers identified trends of vitamin B6 status in a sample
of the United States population based on measures of plasma pyridoxal 5'- phosphate (PLP) levels in the bloodstream. Plasma PLP is the indicator used by the federa...
Understanding how weeds are resistant to herbicides
... data. "Once we obtain the sequence of a resistance gene, we can develop molecular tests that are specific for the resistance mutation. "We can take a sample
of waterhemp from a field that was sprayed and the waterhemp hasn't died and we can confirm whether it is resistant or not because we know the gene se...
Lead-based consumer paint remains a global public health threat
...) for lead in paint. In addition, 69 percent of the brands had at least one sample
exceeding 10,000 ppm. With the majority of American consumer goods being pr...lso analyzed the consumer cost of leaded and unleaded paint.
Each paint sample
was applied in a single layer to a wood block, left to dry and then removed...
Study links virus to some cases of common skin cancer
... cells; and from cells washed from the mouth.
The investigators detected the virus in 26 of 177 SCC samples, 11 of 63 adjacent-skin samples, and one sample
from a mouthwash. They found no viral DNA in any of the blood samples from 57 patients. In all, 21 of 58 SCC patients, or 36 percent, tested positive ...
New computer simulation helps explain folding in important cellular protein
...emarkably, they did. The first step in studying the dimerization process was to estimate those states in GpA using Wang-Landau. The second step was to sample
various energy and structural "observables" of the system to provide insights into the thermodynamics of the entire system.
The results could be br...
Jet-propelled imaging for an ultrafast light source
... than hundreds of thousands of times a second. The sample
jet is designed to shoot droplets right through a ...on't clog, because even a particle bigger than the sample
protein or virus bigger than the stream of liquid...ata-merging also depends partly on knowing how the sample
was oriented in the beam easy to do with a large ...
E-Noses: Testing their mettle against fly noses
...s us to compare technical sensors with biological sensors.
"We looked at how the most common type of e-nose sensors metal oxide or 'MOx' receptors sample
the air around them. This is a critical factor in the performance of all noses. We then compared it with the performance of odorant receptors from t...
University of Toronto helps to 'barcode' the world's plants
...idate gene regions against three criteria: ease of obtaining DNA sequences; quality of the DNA sequences; and ability to tell species apart based on a sample
of 550 species of land plants", says Barrett. "Based on this global analysis we recommended that matK and rbcL two chloroplast genes are adopted as ...
DOE-funded research projects win 46 R&D 100 Awards for 2009
...ons. The technology has been licensed to RFinity of Idaho Falls.
Concentrator Automated portable device that concentrates and packages a sample
of suspected contaminated water for safe, efficient transport to a qualifie...
In vitro antibody production enables HIV infection detection in window period -- key to safer blood
... Experimental Biology and Medicine , show that pre-treating the whole blood sample
in the SMARTube containing immune potentiating agents promoted the synthesi...e production of detectable levels of anti-HIV antibodies in the whole blood sample
and to the detection of potentially infectious blood units which were misse...
Music is the engine of new U-M lab-on-a-chip device
...e, integrates multiple laboratory functions onto one chip just millimeters or centimeters in size. The devices allow researchers to experiment on tiny sample
sizes, and also to simultaneously perform multiple experiments on the same material. There is hope that they could lead to instant home tests for illn...
Reveal the enemy
...This type of procedure usually takes at least two days after arrival of the sample
in the laboratory. Tests that work faster, in the field, and without complex sample
preparation, whilst being precise and error-free, are thus high on the wish...
Scientists report first remote, underwater detection of harmful algae, toxins
... dynamics, such as water temperature and ocean circulation, are influenced by climate.
A MBARI-designed robotic instrument called the Environmental sample
Processor, or 'ESP,' designed as a fully-functional analytical laboratory in the sea, lets researchers collect the algal cells and extract the genetic...
Methane-eating microbes can use iron and manganese oxides to 'breathe'
... of sediment systems including as controls, an autoclaved sterile sample, a sample
with sulfate as a control and a sample
that was sulfate, iron oxide and manganese oxide free, but live. She also i...
New theory gives more precise estimates of large-scale biodiversity
...but increase more slowly for larger and larger areas - a power-law rise with the number of species proportional to the power of the area.
"You can sample
an area and count the number of species, and then double the area and find more species, but not twice as many, because the species overlap," Harte sa...
NIST issues human milk and blood serum SRMs for contaminant measurements
To prepare these SRMs, scientists collected 200 liters of blood serum and 100 liters of milk from banks across the United States and divided the sample
pools in half. (Note that the milk that was used to prepare the SRM was not suitable for feeding babies because the donors may have taken medications ...
New biomarker method could increase the number of diagnostic tests for cancer
...ble isotope dilution mass spectrometry (SID-MS), which is a technique used by protein scientists to measure the abundance of a particular protein in a sample
-- may be suitable for use in preclinical studies to rapidly screen large numbers of candidate protein biomarkers in the hundreds of patient samples n...
Working to conserve endangered 'Playboy' bunnies
...ris paludicola, which is native to South Florida and the Everglades. She is using hair follicles gathered from mainland rabbits to extract DNA. Once sample
collection is finished, Tursi will conduct DNA analysis and compare the diversities of the paludicola and hefneri over the next four or fives months. ...
Novel handheld device detects anthrax with outstanding accuracy and reliability
... producing test results from very small amounts of sample
and does not consume or destroy the sample
being tested, allowing it to be re-analyzed later ..., their accuracy is inferior to the Ceeker and the sample
is typically destroyed during testing.
The new ...
CSHL scientists harness logic of 'Sudoku' math puzzle to vastly enhance genome-sequencing capability
... to past approaches that allowed only a single DNA sample
to be sequenced at a time. It also significantly i...tiplexing approaches, scientists first tagged each sample
with a barcode a short string of DNA letters know...other samples that also had unique tags. After the sample
mix had been sequenced, scientists could use the b...
NYU Langone Medical Center awarded NIH grants totaling $1,560,000
... the HPM will support pilot demonstration projects by researchers that will sample
the microbiomes of healthy volunteers and volunteers with specific diseases...ly stages of esophageal adenocarcinoma than those who do not. His team will sample
the oral cavity, esophagus, and stomach to study the relationship between t...
NIH expands Human Microbiome Project; funds sequencing centers and disease projects
...ot demonstration projects by researchers that will sample
the microbiomes of healthy volunteers and voluntee...tive tract: Obesity
This study will sample
the gut microbiome from obese and non-obese subjec...phageal Adenocarcinoma
This team will sample
the oral cavity, esophagus, and stomach to study t...
An easy way to find a needle in a haystack by removing the haystack
... able to quickly and reliably determine more than 100 different analytes from single and small-sized samples. "The analysis of a very small plant leaf sample
from Arabidopsis thaliana , in fact a circle area with a radius of just about 0.5 millimeter, revealed over a hundred analyte peaks, among which 46 m...
Chemical in blood may explain susceptibility to bladder pain
...dicating the presence or lack of disease based on the samples' molecular profiles. Infrared spectroscopy identifies the biochemical content of a blood sample
based on where peaks of molecules appear in the infrared spectrum. Samples from humans and cats with interstitial cystitis demonstrated nearly identic...
Researchers identify new risk factor gene for rheumatoid arthritis
...s genetic finding is significant because of its key role in immune system regulation. It did not reveal itself in previous genetic studies because the sample
size was just not large enough. In previous studies, genetic samples from about 2,000 patients were used to identify markers associated with risk for ...
Gene activity reveals dynamic stroma microenvironment in prostate cancer
...appears in the current issue of the journal Clinical Cancer Research .
In this study, using special techniques and gene chips that allowed them to sample
the entire genome, the researchers found changes in 1,141 genes. They were either upregulated meaning that there was more of the protein with which t...
Knock-out drugs: Narrow window for detection
...ne and at least 10 mL blood should be taken as quickly as possible. If the interval between the incident and the medical examination is longer, a hair sample
should be taken. This can be done up to 4 weeks after the incident. Involuntarily taken drugs are only detected in routine testing after 2% of offence...
The first hyperspectral scanner in Spain
...ths that are not visible.
This scanner, known as SisuCHEMA, is a work station that integrates all the elements required for acquiring an image of a sample
in a spectral range of 900 to 2500nm, known as SWIR (short-wavelength infrared).
This station will complement the hyperspectral image analysis soft...
Sulphur in just one hair could blow a terrorist's alibi
...onth, the data obtained from a hair measuring between 4cm and 6cm can provide information about its owner's activities in the months leading up to the sample
The results of the experiment revealed that the traveller's hair indeed showed significant variations in the sulphur isotopes, while c...
Toward cheap underwater sensor nets
...r and modem hardware as energy efficient as possible," said Benson.
Greater energy efficiency means batteries can last longer and the sensors can sample
the environment more frequently. Higher sampling rates can greatly increase the utility of the collected data and enable scientists to plan experiment...
Microtest Labs Adds Dissolution Testing to its Suite of Analytical and Stability Testing Services
To estimate release and absorption rates in humans after an in vitro -- in vivo correlation is established
Dissolution is a sample
preparation technique. Samples still need to be analyzed separately, usually by Microtest's HPLC or UV Spectroscopy testing. Typical samples are oral ...
Spring agricultural fires have large impact on melting Arctic
...d environmental engineering at Harvard. Jacob participated in a portion of the campaign known as ARCTAS, which used NASA's DC-8 "flying laboratory" to sample
plumes of air over Arctic regions in Alaska and Canada.
The international team of scientists used satellites, instrumented aircraft, ocean-going sh...
Identification of genetic variants affecting age at menopause could help improve fertility treatment
...AS had not been used to study the effect of genetic variants on age at menopause.
The scientists intend to follow up their work with an even larger sample
of menopausal women to identify more chromosomal loci. "GWAS gives you SNPs connected with menopausal age, and a possible indication of the gene i...
Proteomics: Finding the key ingredients of disease
... analysis techniques worldwide and to identify potential bottlenecks."
Putting them to the test
Twenty-seven labs worldwide were sent a standard sample
of proteins to analyse using their usual techniques. Only seven of the 27 participating labs were accurate in detecting all the proteins and in the mo...
Tumor growth and chemo response may be predicted by mathematical model
... susceptibility of tumors to chemotherapy, he added. The model could augment efforts to predict drug response, which currently include removing a tiny sample
of cancer tissue and testing the response of its cells to cancer drugs in a laboratory situation before the patient starts treatment. By basing the mo...
American Chemical Society's Weekly PressPac -- May 13, 2009
...e new FDA detection guidelines. The techniques take as little as 5 minutes to detect melamine and are relatively simple to use, requiring little or no sample
ARTICLE #1 FOR IMMEDIATE RELEASE
"Melamine Detection in Infant Formula Powder Using Near- and Mid-Infrared Spectroscopy"
Study finds link between individual stress and adolescent obesity
... Journal of Adolescent Health ( http://www.jahonline.org/inpress ) and will be published in its August issue. Forty-seven percent of the teens in the sample
were overweight or obese, but that percentage increased to 56.2 percent among those who were impacted by four or more stressors.
"We found that an ...
MITs implantable device offers continuous cancer monitoring
... CAMBRIDGE, Mass.--Surgical removal of a tissue sample
is now the standard for diagnosing cancer. Such procedures, known as biopsies, are accurate but only offer a snapshot of the tumor at a single moment ...
UCSB scientists document fate of huge oil slicks from seeps at coal oil point
... 400 pounds."
It's the amount of residual oil that made it to the ocean floor that surprised all of the researchers. "Based on what we found in the sample
cores at our sites, we calculated the amount of hydrocarbon in the whole area," Valentine said. "We have to make assumptions about how deep the sedime...
Milestone in live microscopy focus of $2 million NIH grant
...o-DTEM," three new elements must be incorporated into the design: a custom-built system to hold an ultra-thin layer of fluid containing the biological sample
to be imaged; a short-exposure-time imaging mode, to avoid the blurring problem created when molecules move through their fluid medium; and a new gene...