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SLE in Biological News

DNA variations signal lupus risk

...udy, the largest of its kind to date, is the work of the International Consortium for Systemic Lupus Erythematosus (SLEGEN), of which UAB is a member. sle is the medical term for systemic lupus erythematosus, a common form of the disease. Looking at the genomes of 6,728 people, the researchers found t...

UT Southwestern secures $5 million NIH grant for lupus research

...onnected research groups focused on key aspects of sle development. Dr. Mohan, professor of internal ...ocusing on why B-cells start to attack the body in sle patients. Overseeing a group working to identi...c features that mark progression of the disease in sle patients are Dr. Olsen, professor of internal medi...

Lupus gene finding prompts call for more DNA samples

...requently causes skin rash, joint pains and malaise, but can also lead to inflammation of the kidneys and other internal organs. The risk of death in sle is increased fivefold over that of the general population. However, because the symptoms are often non-specific, diagnosing the condition can be diff...

HGS announces positive Phase 2 LymphoStat-B at ACR meeting

... of the American College of Rheumatology (ACR). sle is a chronic disease, and patients need new therap... observed for LymphoStat-B in serologically active sle patients at 52 weeks appears to be sustained throu...ymphoStat-B was well tolerated in combination with sle standard-of-care therapy during long-term exposure...

American Chemical Society's Weekly PressPac -- Sept. 26, 2007

..., kidneys and other body parts. Current treatments for lupus also known as sle include high doses of steroids and other medications with serious side eff...therapy warrants further evaluation as a possible approach for treatment of sle in humans, the report states. ARTICLE #1 FOR IMMEDIATE RELEASE Depletion...

New insights into autoimmunity and depression

...neral and in central nervous system dysfunction in sle in particular. Healthy female mice receiv...P antibodies extracted from the blood sample of an sle patient. For control purposes, equal numbers of mi...atients with clinical depression and patients with sle could help determine whether these pathways are si...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...s therefore possible to imagine the development of methods of treatment for sle based on blocking the function of the thyrosinkinase enzyme," explains Lars...javik provided the project with DNA samples and diagnostic information from sle patients. ...
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