Identification of a key molecular pathway required for brain neural circuit formation
Montral, May 15, 2009 The research group of Dr. Frdric Charron, a researcher at the Institut de recherches cliniques de Montral (IRCM), has made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. This new finding has been published in the current issue of the ...
Cell 'anchors' required to prevent muscular dystrophy
DURHAM, N.C. A protein that was first identified for playing a key role in regulating normal heart rhythms also appears to be significant in helping muscle cells survive the forces of muscle contraction. The clue was a laboratory mouse that seemed to have a form of muscular dystrophy.
Research required urgently to control planthopper pests
Los Baos, Philippines A small insect that has devastated millions of hectares of rice in southern China and Vietnam over the past few yearscausing the loss of thousands of tons of the grain at a crucial time for global productionis the focus of a critical and timely conference this week in the Ph...
Shilatifard Lab sheds light on molecular machinery required for translation of histone crosstalk
The Stowers Institutes Shilatifard Lab has published findings that shed light on the molecular machinery required
for the translation of histone crosstalk, or communication between histones.
Published in todays issue of Cell, Histone Crosstalk between H2B Monoubiquitination and H3 Methylation...
Study identifies pathway required for normal reproductive development
Massachusetts General Hospital (MGH) clinical researchers, in collaboration with basic scientists from the University of California, Irvine (UC Irvine) have identified a new molecular pathway required
for normal development of the reproductive, olfactory and circadian systems in both humans and mi...
Specific brain protein required for nerve cell connections to form and function
CHAPEL HILL Neurons, or nerve cells, communicate with each other through contact points called synapses. When these connections are damaged, communication breaks down, causing the messages that would normally help our feet push our bike pedals or our mind locate our car keys to fall short.
C-myc required by the immune system
c-myc, a gene commonly involved in cancer onset, has been found to have a role in the immune system's normal function according to a study published today in Blood. The surprising finding, by a Swiss research team led by investigators from the Lausanne Branch of the international Ludwig Institute f...
New study reveals signaling pathways required for expansion of pancreas stem cells
IDDM, which used to be referred to as Type 1 diabetes, results from selective destruction of insulin-producing pancreatic islet beta cells by the body's immune system. Islet beta cells are spread throughout the pancreas and are made up of two types of cells: alpha cells, which make glucagon, a horm...
Malignant melanoma cells secrete protein required for embryo formation
A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation.
An article describing this research was published today in the advanced online issue of the journal Nature Medicine. The researchers ident...
Molecular Partners Required For Appropriate Neuronal Gene Repression
Oregon Health & Science University researchers have identified some of the key factors that prevent the repair of brain damage caused by multiple sclerosis (MS), complications of premature birth, and other diseases and conditions. The findings offer important clues about why the nervous system ...
B cells are required for development of epithelial cancer associated with chronic inflammation
Chronic inflammation is linked to the development of certain types of cancer, but mechanisms mediating inflammation during premalignancy are not well understood. A new research study published in the May issue of Cancer Cell identifies B lymphocytes as important regulators of premalignancy associat...
Gene variations explain drug dose required to control seizures
Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University...
Protein handlers should be effective treatment target for cancer and Alzheimer's
...to the proper shape to function properly and even haul them off when they no longer work. Cancer needs them even more for the endless cell replication required
for tumor growth, Dr. Mivechi says. Essentially the opposite happens in Alzheimer's in which excess protein is a major component of the destructive br...
delSECUR CORPORATION Announces Agreement to Purchase the Intellectual Property Assets of the Corporation
...n set forth herein should be read in light of such risks. We assume no obligation to update the information contained in this press release, except as required
under applicable law.
Plankton Power and RTDC announce proposed algae-to-biofuels pilot facility on Cape Cod
...MMR) in Bourne, Massachusetts, supported by the Massachusetts National Guard pending legal and regulatory reviews. The pilot facility will provide the required
infrastructure for testing commercial scale-up of a breakthrough algae-growth technology resulting from 20 years of cold saltwater species research an...
Stem cell 'daughters' lead to breast cancer
.... In BRCA1 women these cells don't even require growth factors to proliferate they misbehave from the outset.
"We also know that the BRCA1 gene is required
for normal DNA repair. There may therefore be a triple whammy effect faulty growth control, faulty DNA repair and expanded luminal progenitor cell nu...
Parasites ready to jump
...ble to tame these "selfish" genetic elements, although highly efficient mechanisms of defence have evolved. For instance, in the germ cells, which are required
for reproduction, the system of so-called piRNAs ensures that transposon activity is inhibited but only if these RNAs are transmitted from the mother...
First genetically-engineered malaria vaccine to enter human trials
...has the only facility worldwide capable of producing genetically-altered malaria parasites that comply with the good manufacturing practice guidelines required
for human clinical trials.
Test helps in fight against lung infections and for treating other life-threatening infections
...c. will now allow doctors to more accurately identify the right antibiotics required
to treat serious, chronic infections that are biofilm based. With more tha...to cause death.
Until bioFILM PA™, treatment of chronic infections required
trying different antibiotics until one or several together eliminated or co...
Indonesia Now Using MegaMatcher Biometric Technology in Integrated Passport Issuance System
...t to generate templates from face and fingerprint images collected at local Indonesian Immigration Offices. These templates, along with scans of other required
documents, are stored on a local server and forwarded automatically by X/LINK SAF (Store and Forward) to the Biometric Matching System at Immigration ...
DOE-funded research projects win 46 R&D 100 Awards for 2009
...with Pulsed Filtered Cathodic Arc Technology a system that promises more computer memory at less cost by depositing thin films of diamond-like carbon required
by next-generation computer hard-disk heads. (Jointly with Veeco Instruments, Inc.)
TEAM Electron Microscope Stage The TEAM Stage will make one ...
High-tech vehicle design boosts emergency rescue capacity
The high capacity model developed in the EUREKA project demanded a different approach from existing equipment. "Our design required
totally new ideas and construction, including use of high performance aeronautics and aerospace materials, such as titanium and carbon fibre," explain...
Improved air quality during Beijing Olympics could inform pollution-curbing policies
...y due to a new emission standard implemented in Beijing in 2008, in which all new registered vehicles as well as gasoline and diesel fuel engines were required
to achieve emissions standards equivalent to European Union regulations. A similar standard was mandated starting in June 2008 for 20,000 buses and 66...
Noise pollution negatively affects woodland bird communities, says CU-Boulder study
... vocal frequencies of mourning doves and black-headed grosbeaks appear to overlap with most human-caused noises, which may inhibit vocal communication required
for repelling rivals, pairing and nesting.
The study indicated birds that were intolerant of noise and nested in quiet areas were subject to great...
EPA grant to University of Chicago for research on food allergy triggers
...igger allergic responses, scientists will be equipped to develop new tests for adverse effects from these foods and interpret data from toxicity tests required
Each year, food allergies instigate more than 30,000 emergency room visits, and in rare cases can lead to death. The number of aller...
Scientists discover gene mutation responsible for hereditary neuroendocrine tumor
...neuroendocrine tumor called paraganglioma (PGL). The gene, called hSDH5, is required
for activation of an enzyme complex that plays a critical role in the chemi...eded for the SDH complex to function normally. They also found that Sdh5 is required
for activation of another protein called Sdh1 that is also part of the SDH ...
Sticky protein helps reinforce fragile muscle membranes
... restored muscle membrane integrity and protected the muscles from damage.
"Injecting the protein helped us prove that glycosylated dystroglycan is required
to attach the membrane to the extracellular proteins and thus reinforce the membrane integrity," said Campbell, who also holds the Roy J. Carver Chair...
High construction cost for cycads
... indicate the construction costs of this leaf form are substantial."
Green leaves must pay back their own construction costs, but each leaf is also required
to supply the energy needed to maintain its live tissues throughout its lifespan. Additionally, large plants like Guam's Cycas have an abundance of ...
Tires made from trees -- better, cheaper, more fuel efficient
...tially replace silica as a reinforcing filler in the manufacture of rubber tires.
A new study suggests that this approach might decrease the energy required
to produce the tire, reduce costs, and better resist heat buildup. Early tests indicate that such products would have comparable traction on cold or w...
University of Minnesota research leads to new technology to protect human health
... Organization (WHO) for a simple, inexpensive method to detect melamine contamination in infant formula and other liquids. Until now, melamine testing required
expensive laboratory equipment and skilled personnel. This kit simplifies the testing and reduces the cost of melamine detection. The MaxDiscovery Mel...
Ethiopian government celebrates rinderpest eradication
...ile traveling to isolated areas," said Catley, who is also an assistant professor at The Friedman School of Nutrition Science and Policy at Tufts. "It required
refrigeration facilities, ice machines, cold boxes and fleets of vehicles. They needed an easier way to deliver the vaccine."
By 1990, three years ...
Scientists report first remote, underwater detection of harmful algae, toxins
...r 'ESP,' designed as a fully-functional analytical laboratory in the sea, lets researchers collect the algal cells and extract the genetic information required
for organism identification as well as the toxin needed to assess the risk to humans and wildlife. The ESP then conducts specialized, molecular-based ...
A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline
...ted with increased risk of cognitive impairment. At the same time, long-term physical activity is associated with improved cognition but the intensity required
to preserve cognition is not known.
Mary C. Tierney, PhD, CPsych, Professor of Family and Community Medicine at the University of Toronto, and Sen...
Parascript Signature Verification Technology Used by Moscow Law Firm to Detect Signature Fraud in $160,000 Debt Collection Case
... all instances. Knowledge of the law, high qualifications, and experience in conducting trials enable unconventional approach to judicial proof issues required
by the customers. Clients include Russian and Forbes 500 international companies.
Children's Hospital of Pittsburgh of UPMC scientists identify enzyme important in aging
... PAPPA controls the availability in tissues of a hormone known as insulin-like growth factor (IGF) that is a promoter of cell division. Hence, IGF is required
for normal embryonic and postnatal growth. But IGF also is associated with tumor growth, inflammation and cardiovascular disease in adults. By deletin...
UAB students' Nintendo Wii CPR earns American Heart Association support
...st spring semester for their senior project."
The UAB team worked on the Wii CPR project for its Design in BME biomedical engineering course, which required
the students to successfully design and construct a prototype of the technology for real-world use in order to pass the course. After a successful cla...
22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey
...ntia or neurological and addictive disorders in the most rational and empirical manner.
Neuropsychopharmacological research provides data that are required
to develop drugs, which act on specific receptors within a neurotransmitter system. The pharmacological progress achieved in recent decades is mainly ...
A matter of density, not quantity
...ther seed a macroscopic volume with bacteria and wait for them to reach the required
population through cell division, or enclose a few cells in an extremely ti...ny cases. "This unambiguously refutes the notion that millions of cells are required
for quorum sensing," says Ismagilov.
Toward an explanation for Crohn's disease?
...ycobacteria, but researchers must still determine the precise combination of these factors to understand how the disease develops.
More research is required
to establish a complete explanation. From this, it is expected that new therapeutic approaches that fight the cause of Crohn's disease may be develop...
Landmark project to map genomics of complex ant systems
...oughput genome sequencing technology, which will provide 10 giga-bases of data an amount equivalent to three human genomes. Previously, it would have required
millions of dollars and extensive manpower to sequence just one organism.
"We're entering completely new territory," says James Taylor, assistant p...