Navigation Links
Regulating in Biological News

Key protein regulating inflammation may prove relevant to controlling sepsis

Scientists at Singapore's Institute of Molecular and Cell Biology (IMCB), under the Agency for Science, Technology and Research (A*STAR), have identified the protein, WIP1, as the molecular "brake" that curbs severe inflammation in the body. The findings may prove relevant to developing m...

JDRF-funded researchers discover proteins regulating human beta cell replication

NEW YORK, January 16, 2009 - Researchers at the University of Pittsburgh School of Medicine, funded by JDRF, have discovered that adult beta cells have the ability to replicate with the help of a protein known as cdk6. This research was led by Andrew F. Stewart, M.D., a Professor of Medicine and ...

Food for thought -- regulating energy supply to the brain during fasting

LA JOLLA, CAIf the current financial climate has taught us anything, it's that a system where over-borrowing goes unchecked eventually ends in disaster. It turns out this rule applies as much to our bodies as it does to economics. Instead of cash, our body deals in energy borrowed from muscle and ...

CSHL team traces extensive networks regulating alternative RNA splicing

Two professors at Cold Spring Harbor Laboratory (CSHL) have succeeded in tracing intricate biochemical networks involving a class of proteins that enable genes to express themselves in specific tissues at particular moments in development. Michael Q. Zhang, Ph.D. and Adrian R. Krainer, Ph.D.,...

Glypican-3 gene function in regulating body size helps inform novel cancer treatments

Toronto (May 13, 2008) - In a leading study that has implications for the development of novel therapies for a number of breast, lung and ovarian cancers that have lost the expression of a gene called glypican-3 (GPC3), Sunnybrook researchers have discovered how the loss of the GPC3 gene induces o...

2 genes are important key to regulating immune response

NEW YORK (Dec. 28, 2007) -- A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10). The discovery fills in an important "missing link" in a biochemical pathway ...

Scientists discover new regulating mechanism in cells

Researchers here have discovered a new mechanism used by cells ?and manipulated by retroviruses ?to control the making of certain essential proteins, including some involved in cancer. The mechanism uses an enzyme called RNA helicase A (RHA), which is made by the cell. The study by researche...

Protein's role in regulating cell death sets direction for cancer research

A protein called calpain can be the key either preventing or promoting the cell death, a Queen's University study has found. "This work provides proof in principle that pharmacological inhibition of calpain may be used to block cell death in situations where this is not desirable, such as in neu...

Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation

Disruption of a single gene, Nrf2, plays a critical role in determining the susceptibility to asthma. A research team led by Shyam Biswal, PhD, at the Johns Hopkins Bloomberg School of Public Health found the absence of Nrf2 exacerbated allergen-mediated asthma in mice models. The study’s findings,...

Mechanism regulating tooth shape formulation found

One of the remaining challenges for evolutionary developmental studies of mammals, whose evolution is best known from their teeth, is how their tooth shape is altered during development. Researchers of the University of Helsinki together with their Japanese colleagues from the University of Kioto n...

A new mechanism of regulating RNA degradation

At first, we thought that gene expression was modulated only by transcription factors. Then we found that the RNA resulting from transcription could be regulated by the RISC complex (siRNA-mediated degradation via Dicer). And now it seems that regulation at the RNA level is even more complex than ...

NIH stimulus funding supports Emory biomedical scientists

...prostate cancer: The nutrient phosphate is an additive in products ranging from soft drinks to meats and bakery goods, but it plays a critical role in regulating cell growth and could encourage tumor formation. This project monitors the influence of dietary phosphate on a mouse model of prostate cancer. Unde...

AGU journal highlights -- Aug. 6, 2009

...entists understand the mechanics of how stratospheric ozone becomes depleted through interactions with these short-lived compounds. Title: Process regulating short-lived species in the tropical tropopause layer Authors: A. Gettleman and M. Park: Atmospheric Chemistry Division, National Center for Atmosph...

Reprogramming human cells without inserting genes

... only does this data force us to rethink what the true markers of pluripotency may be, it suggests there is a natural mechanism at work in these cells regulating the stem cell gene expression. That opens a whole new line of inquiry." ...

Common allergy drug reduces obesity and diabetes in mice

...ar more abundant in fat tissue from obese and diabetic humans and mice than they were in normal weight fat tissue. This led to an obvious question: by regulating mast cells, could we then control the symptoms? To find out, Shi and colleagues took a group of obese and diabetic mice and, for a period of two mo...

Improved air quality during Beijing Olympics could inform pollution-curbing policies

...ording to a Cornell study. Led by Max Zhang, assistant professor of mechanical and aerospace engineering, the study indicates that such measures as regulating traffic density and encouraging public transportation can have a significant impact on local air quality. "We hope our study can help or advise loc...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

... Paragangliomas are rare, generally benign tumors that arise from cells called glomus cells, which are located along blood vessels and play a role in regulating blood pressure and blood flow. Approximately 25 percent of paragangliomas are hereditary. Of the four familial PGL syndromes, three forms have previou...

A genetic basis for schizophrenia

...ased expression of these factors, leading to hindered cell migration and a change in cell fate. "This research indicates that Disc1 may be involved in regulating stem cells and their fate," says Morris. The second paper, published in the June 2009 online issue of Human Molecular Genetics , studied the hippo...

Genetic marker linked to problem behaviors in adults with developmental disabilities

... A common variation of the gene involved in regulating serotonin and norepinephrine in the brain may be linked to problem behaviors in adults with developmental and intellectual disabilities, new research ...

Ozone, nitrogen change the way rising CO2 affects Earth's water

...published their findings recently in the Journal of Geophysical Research Biogeosciences. Plants play a significant role in Earth's water cycle, regulating the amount of water cycling through land ecosystems and how long it stays there. Plants draw in water from the atmosphere and soil, and they discharge...

Plant protein 'doorkeepers' block invading microbes, study finds

...ut invading bacteria," Coaker said. She noted that, over the last 20 years, scientists have identified a number of proteins that are important for regulating the plant immune system but still do not have a good sense of what protein complexes these proteins belong to and how they signal to confer disease re...

Iron and biological production in the high-latitude North Atlantic

... Southampton scientists have demonstrated an unexpected role of iron in regulating biological production in the high-latitude North Atlantic. Their findings have important implications for our understanding of ocean-climate interacti...

Canadian researchers set to study impact of nanomaterials on aquatic ecosystems

...he potential effects of nanoparticles in specific water environments. "Nanotechnology is a very new and quickly developing field. Governments and regulating agencies around the world are seeking solid scientific data upon which to base their regulatory standards," said Greg Goss, project co-leader and prof...

Axel Ullrich named winner of 2009 Dr. Paul Janssen Award for Biomedical Research

...asis of a newly discovered gene with an oncogenic function in human cancer. In the early 1990s, Ullrich identified the signaling system involved in regulating tumor angiogenesis, the growth of blood vessels in tumors. He discovered that inhibiting a key player in the signaling system (called vascular endoth...

Plant protein 'doorkeepers' block invading microbes, study finds

...ut invading bacteria," Coaker said. She noted that, over the last 20 years, scientists have identified a number of proteins that are important for regulating the plant immune system but still do not have a good sense of what protein complexes these proteins belong to and how they signal to confer disease re...

Xie Lab uncovers molecular machinery related to stem cell fate

...rotein affects germline stem cell differentiation and how it is involved in regulating the quality of stem cells through intercellular competition. The work was p...and senior author on the paper. "Translational control is very important in regulating gene expression. Many genes critical for stem cell development in the fruit...

Cells use import machinery to export their goods as well

...s from outside the cell, called endocytosis. But, in a paper to be published June 26 in Cell , Jaiswal and Simon show that some of the key molecules regulating endocytosis, such as clathrin, dynamin and actin, are also at work in exocytosis. "In retrospect, it makes perfect sense," Jaiswal says. "But at ...

Nematode courting caught on camera

...son Whittaker and Paul Sternberg from the California Institute of Technology investigated the role of the excitatory neurotransmitter acetylcholine in regulating tail muscles to achieve an exploratory embrace. The video shows an intimate moment between two nematodes of the species Caenorhabditis elegans . ...

Tumor suppressor gene in flies may provide insights for human brain tumors

...rowth. "We were very surprised when we found that PP2A also suppressed tumors," Wang said. Follow-up experiments showed that PP2A is important for regulating Polo kinase function, and showed that these two critical brain tumor suppressors work together to control neural stem cell divisions. "Our discove...

Researchers observe single protein dimers wavering between two symmetrically opposed structures

... in The Proceedings of the National Academy of Sciences ( PNAS ) on June 8, 2009, emphasizes that such shape shifting by proteins is a common way of regulating cellular activities. This direct view provides a neat example of the dynamic and complex nature of proteins, contrasting with a single preferred folde...

Protein regulates movement of mitochondria in brain cells

...e cell body perhaps to be recycled or replenished in some form. Rempe and his colleagues have discovered a protein that plays a critical role in regulating the movement or transport of mitochondria in neuron cells. The protein, which they dubbed hypoxia upregulated mitochondrial movement regulator (HUMM...

Dual role in breast tissue for a protein involved in leukemia

...toral graduate student in tumor biology at Georgetown University Medical Center. Stat5a is a member of the STAT family of proteins, which are key to regulating cell growth and differentiation. Because they have been found to be over-expressed in leukemia, Miermont and Priscilla Furth, MD, a professor of oncol...

Embryology study offers clues to birth defects

...tissues during embryogenesis. These processes are regulated by signaling molecules that control the growth and differentiation of progenitor cells by regulating specific genes. One of these signaling molecules is retinoic acid, a metabolite produced from vitamin A (retinol), which plays a key role in the deve...

Researchers identify new risk factor gene for rheumatoid arthritis

...mber of the NF-B family, important transcription factors that have many roles in the body. The NF-B family seems to have a big hand in regulating the body's immune response as well. "The NF-is a key switching point for many cellular activities," said Peter K. Gregersen...

USC researchers present diabetes findings at American Diabetes Association Scientific Sessions

... Casey Donovan, Ph.D., professor of kinesiology and biology, will discuss his research on the role of the brain and the portal vein in sensing and regulating low blood sugar. Building on his research that determined the portal vein connecting the pancreas and liver has glucose sensors that alert the bod...

Jefferson receives $1.7 million grant to study stem cells in intervertebral discs of the spine

....7 million National Institutes of Health grant funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases to study mechanisms regulating stem cell self-renewal and differentiation with the aim of regenerating diseased and painful intervertebral discs. A previous study by the same group ...

MicroRNAs grease the cell's circadian clockwork

...me. "We have studied the role of a microRNA called miR-122, which is highly abundant in liver. It has caught considerable attention for its role in regulating cholesterol and lipid metabolism and in aiding the replication of hepatitis C virus" explains David Gatfield, one of Professor Schibler's collaborator...

'Disordered' amino acids may really be there to provide wiggle room for signaling protein

...in-binding tail, effectively shutting the protein down. "The flexibility of the linker and its tendency to be more or less disordered are critical for regulating the balance between internal ("autoinhibitory") forces and external interactions with the protein's signaling partners" Roder says. This idea is reinf...

Bolivian rainforest study suggests feeding behavior in monkeys and humans have ancient, shared roots

...tionally-balanced food sources that are used extensively by a wild population may need special attention in terms of conservation planning, perhaps by regulating logging and selecting certain tree species for re-planting. The majority of the monkeys' nourishment was sourced from a species of fig tree, Ficus bol...

Low levels of vitamin D linked to common vaginal infection in pregnant women

...nsufficient levels of vitamin D. They also found that the prevalence of BV decreased as vitamin D levels rose. Vitamin D may play a role in BV by regulating the production and function of antimicrobial molecules, which in turn may help the immune system prevent and control bacterial infection. However, onl...
Other Tags
(Date:12/5/2014)... , Dec. 4, 2014 Increased ... boosted investments in new testing and inspection technologies. ... given rise to a range of innovative test ... requirements of Generation Y, which is generally more ... a result, product development strategies of test equipment ...
(Date:11/21/2014)... , November 18, 2014 According ... Market by Systems (Video, RFID, Access Control, Intrusion Detection, ... Hotels, Banks, Government), Component Service Geography - Global Forecasts ... Market is projected to be around $25 Billion in ... 2020, growing at a CAGR of 8.69%. ...
(Date:11/18/2014)... , Nov. 18, 2014  The Secure Identity ... Association today jointly announce the formation of The ... of its Identity and Biometric Entry and ... Framework received official support from BORDERPOL, the international ... improve and provide expertise regarding border security, traveler ...
Breaking Biology News(10 mins):Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
(Date:12/26/2014)... (PRWEB) December 26, 2014 India Network ... insurance in the USA, announced today a new version ... members in choosing the right plan for their visiting ... complexity out of the selection process when choosing an ... age group with only a few clicks. Many elderly ...
(Date:12/26/2014)... December 26, 2014 Parker & ... the best in heating, cooling and plumbing contractor ... hour emergency services in 2014 with regard to ... that Arizona is known for its incredibly hot ... understands the intricacies and details of a wide ...
(Date:12/25/2014)... The click strand woven bamboo flooring ... the business announces a click strand woven bamboo ... 2015. , Click strand woven bamboo flooring replicates ... well-known brand in the bamboo industry. It promises ... bamboo flooring supplier. , “We are happy to ...
(Date:12/25/2014)... 25, 2014 Product liability lawsuits filed ... recall ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in ... Order issued in the U.S. District Court, Northern District ... an open conference on January 7, 2015, at the ... in West Palm Beach, Florida. The Conference is scheduled ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online ... its collection of discounted prom dresses, most of which ... spokesman of the company, the promotion is valid until ... to expand the UK market. , The prom dresses ... lengths, and styles: A-line strapless, empire strapless chiffon, one ...
Breaking Medicine News(10 mins):Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 3Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2
Other Contents