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Prostate in Biological News

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

Researchers from NewYork-Presbyterian Hospital/Weill Cornell Medical Center have discovered a new gene fusion that is highly expressed in a subset of prostate cancers. The results may lead to more accurate prostate cancer testing and new targets for potential treatments. Experts believe that gene ...

Genetic factors implicated in survival gap for breast, ovarian or prostate cancer

NEW YORK (July 8, 2009) A new finding reveals that African-American patients with breast, ovarian, and prostate cancer tend to die earlier than patients of other races with these cancers, even when they receive identical medical treatment and when socioeconomic factors are controlled for. The fin...

Green tea may affect prostate cancer progression

PHILADELPHIA According to results of a study published in Cancer Prevention Research , a journal of the American Association for Cancer Research, men with prostate cancer who consumed the active compounds in green tea demonstrated a significant reduction in serum markers predictive of prostate c...

Gene activity reveals dynamic stroma microenvironment in prostate cancer

HOUSTON -- (June 9, 2009) As stroma the supportive framework of the prostate gland react to prostate cancer, changes in the expression of genes occur that induce the formation of new structures such as blood vessels, nerves and parts of nerves, said researchers at Baylor College of Medicine in ...

3-D research model tackles prostate cancer spread

Shirly Sieh, a PhD student at IHBI, is studying the way cancer cells escape from the prostate through the bloodstream to form tumour colonies, most often in the spine and long bones. "It is an innovative study which uses a tissue engineering platform technology developed by IHBI's Professor Diet...

Agent Orange exposure increases veterans' risk of aggressive recurrence of prostate cancer

AUGUSTA, Ga. - Veterans exposed to Agent Orange are at increased risk of aggressive recurrence of prostate cancer, researchers report. A study of 1,495 veterans who underwent radical prostatectomy to remove their cancerous prostates showed that the 206 exposed to Agent Orange had nearly a 50 pe...

New drug shows promise in treating drug-resistant prostate cancer

A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs. Chemists and biologists at UCLA and colleagues at several other institutions, including Memorial Sloan-Kettering Cancer...

New medications show promise in treating drug-resistant prostate cancer

A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs. Of 30 men who received low doses of one the drugs in a multisite phase I/II trial designed to evaluate safety, 22 showed a...

Freezing prostate cancer does a man's body good

SAN DIEGO, Calif. (March 9, 2009)The so-called "male lumpectomy"a minimally invasive interventional radiology treatment for prostate canceris as effective as surgery in destroying diseased tumors and can be considered a first-line treatment for patients of all risk levels and particularly those wh...

Dana-Farber oncologists present at ASCO GU -- predict prostate cancer survival using Source MDx test

Orlando, Fla., February 27, 2009 Dana-Farber Cancer Institute (DFCI) and Source MDx today announced that Source MDx's whole blood RNA transcript-based Precision Profiles diagnostic test predicted survival in men with castration-resistant prostate cancer (CRPC). In a study of 62 CRPC patients, th...

New lab evidence suggests preventive effect of herbal supplement in prostate cancer

PHILADELPHIA DHEA is a natural circulating hormone and the body's production of it decreases with age. Men take DHEA as an over-the-counter supplement because it has been suggested that DHEA can reverse aging or have anabolic effects since it can be metabolized in the body to androgens. Increased...

Men with wives, significant others more likely to be screened for prostate cancer

PHILADELPHIA Although the link between early screening and prostate cancer survival is well established, men are less likely to go for early screening unless they have a wife or significant other living with them, according to a study published in Cancer Epidemiology, Biomarkers and Prevention ,...

Genetic risk factors may tailor prostate cancer screening approaches

Men with a family history of prostate cancer and African-American men are particularly susceptible to the disease, with a twofold to sevenfold increased risk. Assessing risk in these populations has been difficult. "There have been years of effort to try to identify genes and genetic mutations ...

Height linked to risk of prostate cancer development and progression

PHILADELPHIA A man's height is a modest marker for risk of prostate cancer development, but is more strongly linked to progression of the cancer, say British researchers who conducted their own study on the connection and also reviewed 58 published studies. In the September issue of Cancer Ep...

Why a common treatment for prostate cancer ultimately fails

Some of the drugs given to many men during their fight against prostate cancer can actually spur some cancer cells to grow, researchers have found. The findings were published online this week in a pair of papers in the Proceedings of the National Academy of Sciences . The results may help exp...

Exposure to Agent Orange linked to prostate cancer in Vietnam veterans

(SACRAMENTO, Calif.) UC Davis Cancer Center physicians today released results of research showing that Vietnam War veterans exposed to Agent Orange have greatly increased risks of prostate cancer and even greater risks of getting the most aggressive form of the disease as compared to those who we...

UCLA researchers locate and image prostate cancer as it spreads to lymph nodes

Using an engineered common cold virus, UCLA researchers delivered a genetic payload to prostate cancer cells that allowed them, using Positron Emission Tomography (PET), to locate the diseased cells as they spread to the lymph nodes, the first place prostate cancer goes before invading other organ...

Counting tumor cells in blood predicts treatment benefit in prostate cancer

Counting the number of tumor cells circulating in the bloodstream of patients with castration-resistant prostate cancer can accurately predict how well they are responding to treatment, new results show. At the ESMO Conference Lugano (ECLU) organized by the European Society for Medical Oncology...

Urologists identify 7 biomarkers that may help pinpoint prostate cancer recurrence

DALLAS June 15, 2008 A simple blood test may help doctors better predict whether prostate cancer will recur or spread in patients who have undergone surgery for the disease, researchers at UT Southwestern Medical Center have found. In a study published in the June 15 issue of Clinical Cancer...

Certain form of tomatoes could be key to prostate cancer prevention

COLUMBIA, Mo. New cancer research from the University of Missouri suggests that eating a certain form of tomato product could be the key to unlocking the prostate cancer-fighting potential of the tomato. The positive effect of tomato products has been suggested in many studies, but, until now, re...

Estrogen helps drive distinct, aggressive form of prostate cancer

NEW YORK (May 27, 2008) -- Using a breakthrough technology, researchers led by a Weill Cornell Medical College scientist have pinpointed the hormone estrogen as a key player in about half of all prostate cancers. Estrogen-linked signaling helps drive a discrete and aggressive form of the diseas...

Genes may play role in risk assessment for prostate cancer among Hispanics and caucasians

PHILADELPHIA Genetic differences may explain the greater risk for prostate cancer among Caucasian men compared with Hispanic men, which could help clinicians predict who is more likely to develop the disease, according to a paper published in the May 15, 2008, issue of Clinical Cancer Research, a...

Potential association of type 2 diabetes genes with prostate cancer

ANN ARBOR, Mich.---Scientists have identified six new genes which play a role in the development of type 2 diabetes, and among the group is the second gene known to also play a role in prostate cancer. The new findings bring the total number of genes or genomic regions implicated in diabetes to...

New, noninvasive prostate cancer test beats PSA in detecting prostate cancer

An experimental biomarker test developed by researchers at the University of Michigan more accurately detects prostate cancer than any other screening method currently in use, according to a study published in the February 1 issue of Cancer Research, a journal of the American Association for Cance...

Nanomedicine research for prostate cancer supported by $5 million gift

NEW YORK (Jan. 29, 2008) -- The Prostate Cancer Foundation, largely through the generosity of David H. Koch, has given $5 million to four institutions, including Weill Cornell Medical College, to support novel research in prostate cancer. The gift is one of the largest-ever individual donations fo...

Safeway Inc. and PCF to fund landmark prostate cancer research collaboration

WASHINGTON, DC -- Safeway Inc. and the Prostate Cancer Foundation today announced they will collectively donate $6 million to fund the S.T.A.R. Program (for Special Team Amplification of Research), an innovative research initiative focused on exploring the role of targeted heat in cancer therapy t...

New genetic variant associated with prostate cancer in African-Americans

Two tiny genetic variations may provide the best clues yet for finding more precise ways to estimate prostate cancer risk and improve screening and early detection for men of African descent, report researchers from the University of Chicago and the Translational Genomics Research Institute, Phoen...

Leading researchers to reveal comprehensive dos and don'ts for prostate cancer

Lake Tahoe, CA, October 13, 2007Today at the Prostate Cancer Foundations Annual Scientific Retreat, researchers will share new findings on how eating common foods such as tomatoes and fish, maintaining a healthy weight, and avoiding meats cooked at high temperatures may help prevent prostate cance...

New prostate cancer research findings

WHAT: The 2007 Prostate Cancer Foundation Scientific Retreat will feature new studies by the worlds leading researchers in prostate cancer. Presentations include discoveries expected to lead to new diagnostics and treatments, and the potential to help men avoid developing prostate cancer. ...

University of Minnesota study refutes belief that black men have more aggressive prostate cancer

A University of Minnesota study of prostate cancer tumors from Caucasian and African-American men has shown no evidence that the cancer is more aggressive in black men. Lead investigator Akhouri Sinha, a professor of genetics, cell biology, and development and research scientist at the Minneapolis...

Biomarker predicts malignancy potential of HG-PIN lesions in the prostate

PHILADELPHIA Men whose prostate cancer screenings show high grade prostatic intraepithelial neoplasia (HG-PIN) may find themselves in limbo, stuck between diagnoses they are told prostate cancer has not yet developed, but it might, and they are advised to undergo repeated needle biopsies as a pr...

Heavy multivitamin use may be linked to advanced prostate cancer

While regular multivitamin use is not linked with early or localized prostate cancer, taking too many multivitamins may be associated with an increased risk for advanced or fatal prostate cancers, according to a study in the May 16 issue of the Journal of the National Cancer Institute . Millions...

No magic tomato? Study breaks link between lycopene and prostate cancer prevention

Tomatoes might be nutritious and tasty, but don’t count on them to prevent prostate cancer. In the May issue of Cancer Epidemiology, Biomarkers & Prevention, researchers based at the National Cancer Institute and Fred Hutchinson Cancer Research Center report that lycopene, an antioxidant predo...

Gene elevating breast cancer risk also causes prostate cancer

Cancer is a complex and common disease caused by a combination of both genetic and environmental factors. An inherited predisposition seems to be involved in at least 5?0 per cent of all cases of breast cancer. The two major familial breast cancer susceptibility genes BRCA1 and BRCA2 only explain 2...

Radiation therapy combo cures prostate cancer long-term

Seventy-four percent of men treated with a combination of radiation seed implants and external beam radiation therapy for prostate cancer are cured of their disease 15 years following their treatment, according to a study released today in the International Journal of Radiation Oncology*Biology*Phy...

Inflammation may play role in metastasis of prostate cancer

Many would assume that "mounting an immune response" or "having your body fight the cancer" is a good thing. Now, research at the University of California, San Diego (UCSD) School of Medicine strongly suggests that inflammation associated with the progression of tumors actually plays a key role in...

Sunshine pill for prostate cancer in 2009

A tablet designed to emulate the healing power of the sun could be available for the treatment of advanced prostate cancer as early as 2009. But it remains to be seen whether the drug will be the revolution in prostate cancer care that its makers claim. The drug, Asentar (DN-101), is based on vi...

Nanoparticles for delivery of prostate cancer treatment

Alan Garen , professor of molecular biophysics and biochemistry at Yale has received a $100,000 award from the Prostate Cancer Foundation to expand research on the delivery of a targeted therapy for prostate cancer using nanoparticles. Garen and his collaborator Zhiwei Hu have developed a w...

Men with prostate cancer avoid radiation due to misconceptions

Negative perceptions about radiation therapy can strongly influence a prostate cancer patient's choice to avoid external beam radiation therapy, even though studies have proven the treatment to be as safe and effective as other treatments for the disease, including surgery, according to a study pre...

Scientists discover way to block growth of prostate cancer cells

Scientists have discovered for the first time a specific biochemical pathway by which the sex hormone, androgen, increases levels of harmful chemicals called reactive oxygen species (ROS) in the prostate gland that play a role in the development of prostate cancer. They found that a drug that blo...
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