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Scripps-led study shows ocean health plays vital role in coral reef recovery

The new research study led by scientists at Scripps Institution of Oceanography at UC San Diego suggests that by improving overall ocean health, corals are better able to recover from bleaching events, which occur when rising sea temperatures force corals to expel their symbiotic algae, known as z...

Newly discovered gene plays vital role in cancer

[PRESS RELEASE, 27 February 2009] Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously unknown gene, Wrap53, controls the activity of p53...

NYU Langone Medical Center researchers find micro RNA plays a key role in melanoma metastasis

NEW YORK CITY (February 5, 2009)Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly. Now, scientists from NYU Langone Medical Center have identifi...

Compromised skin barrier function plays a role in psorasis development

Researchers at the Genome Institute of Singapore (GIS) and the Anhui Medical University, China, have identified genes that play an important role in the development of psoriasis, a common chronic skin disease. The research, led by GIS Human Genetics Group Leader and Associate Prof. Liu Jianjun,...

Queen's University Belfast plays leading role in Europe-wide tests for safer food

A top food scientist at Queen's University Belfast is playing a major role in a 4m European project to develop new techniques to detect chemical contaminants in food and animal feed. Professor Chris Elliott, Director of the Institute of Agri-Food and Land Use at Queen's, will lead a team of...

Master gene plays key role in blood sugar levels

When mice that lack steroid receptor-2 (SRC-2) a master regulator gene called a coactivator fast for a day, their blood sugar levels plummet. If they go another day without food, they will die. The severity of the hypoglycemia (low blood sugar) was unexpected, said Dr. Bert W. O'Malley, chai...

Mysterious microbe plays important role in ocean ecology

An unusual microorganism discovered in the open ocean may force scientists to rethink their understanding of how carbon and nitrogen cycle through ocean ecosystems. A paper describing the new findings appears in the November 14 issue of the journal Science . A research team led by Jonathan ...

Wake Forest plays integral role in effort to revolutionize vehicle safety

WINSTON-SALEM, N.C. From stiff plastic limbs and metal rods to complex virtual humans made of muscle, tendon and bone, the crash test dummies of yesteryear are evolving and researchers at Wake Forest University School of Medicine are among those bringing them to life. This new generation of h...

Study finds genetic variant plays role in cleft lip

University of Iowa researchers and collaborators have found, in a previously identified gene, a variation that likely contributes to one in five cases of isolated cleft lip. It is the first time a genetic variant has been associated with cleft lip alone, rather than both cleft lip and palate. T...

Protein identified that plays role in blood flow

COLUMBIA, Mo. For years, researchers have known that high blood pressure causes blood vessels to contract and low blood pressure causes blood vessels to relax. Until recently, however, researchers did not have the tools to determine the exact proteins responsible for this phenomenon. Now, using a...

Early parenting plays key role in infants' physiological response to stress

In infancy, genes are the key influence on a child's ability to deal with stress. But as early as 6 months of age, parenting plays an important role in changing the impact of genes that may put infants at risk for responding poorly to stress. That's the message from a new study by researchers a...

Moss protein plays role in Alzheimer's disease

Preventing Alzheimers from developing is a goal of Raphael Kopan, Ph.D., professor of molecular biology and pharmacology at the Washington University School of Medicine. The moss plant (Physcomitrella patens) studied in the laboratory of Ralph S. Quatrano, Ph.D., Spencer T. Olin Professor and cha...

Small RNA plays parallel roles in bacterial metabolism

They are often overlooked, and were once thought to be too small to contribute much to major cellular processes, but in recent years the study of small ribonucleic acids (sRNA) has gained momentum. Now a team from the University of Illinois has identified the unique metabolic activities of one of ...

Speed plays crucial role in breaking protein's H-bonds

Researchers at MIT studying the architecture of proteins have finally explained why computer models of proteins behavior under mechanical duress differ dramatically from experimental observations. This work could have vast implications in bioengineering and medical research by advancing our unders...

Confirmed -- deforestation plays critical climate change role

Dr Pep Canadell, from the Global Carbon Project and CSIRO Marine and Atmospheric Research, says today in the journal Science that tropical deforestation releases 1.5 billion tonnes of carbon each year into the atmosphere. "Deforestation in the tropics accounts for nearly 20 per cent of carbon em...

Motor protein plays key role in connecting neurons

A motor protein called myosin X runs the main road of a developing neuron, delivering to its tip a receptor that enables it to communicate with other neurons, scientists say. In another piece of the puzzle of how neurons form connections, researchers have found myosin X travels a portion of a ...

Anticipation plays a powerful role in human memory, brain study finds

Psychologists have long known that memories of disturbing emotional events - such as an act of violence or the unexpected death of a loved one - are more vivid and deeply imprinted in the brain than mundane recollections of everyday matters. Probing deeper into how such memories form, researcher...

Fish species plays surprise role in aiding coral reef recovery

In a study that marks progress in understanding the basis of coral reef recovery, researchers have revealed the critical importance of a rare batfish, Platax pinnatus, in promoting the return to health of a disturbed coral reef overgrown with algae. The findings bring to light a previously unrecogn...

Zinc plays important role in brain circuitry

To the multitude of substances that regulate neuronal signaling in the brain and spinal cord add a new key player: zinc. By engineering a mouse with a mutation affecting a neuronal zinc target, researchers have demonstrated a central role for zinc in modulating signaling among the neurons. Signific...

Got inexpensive contrast agent? Milk plays new role in imaging

In a new twist on the slogan “milk does a body good,?radiologists are testing use of the dairy staple as a contrast agent in gastrointestinal imaging exams—with excellent results. The researchers reported their findings today at the annual meeting of the Radiological Society of North America (RSNA)...

Neural stem cell gene plays crucial role in eye development

Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place. Neural stem cells are cells that can differentiate into different cell types in the ne...

Sleeping beauty plays a significant role in identifying cancer genes

Researchers at the University of Minnesota Cancer Center and the National Cancer Institute (NCI), part of the National Institutes of Health, have discovered a new method that could accelerate the way cancer-causing genes are found and could lead to a more accurate identification of the genes, accor...

Micro-molecule plays big role in birth defects

University of Florida researchers have learned how to selectively shut down a flyweight-sized genetic molecule that packs a heavyweight punch, a discovery that may help doctors better understand cancer, birth defects and other health problems. The finding, which will be reported this week in the ...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

A new research study identifies a critical inhibitory step that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying neutrophils is act...

White blood cell waste disposal system plays critical regulatory role

A new research study identifies a critical inhibitory step that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying neutrophils is act...

An HIV Protein Plays a Surprising Role in Gene Activation

Retroviruses are expert manipulators when it comes to co-opting their host's cellular resources. A great deal of human complexity stems from the vast repertoire of proteins and mechanisms dedicated to the business of regulating gene expression, and retroviruses like HIV have evolved myriad ways of ...

NIH stimulus funding supports Emory biomedical scientists

... Dietary phosphate and prostate cancer: The nutrient phosphate is an additive in products ranging from soft drinks to meats and bakery goods, but it plays a critical role in regulating cell growth and could encourage tumor formation. This project monitors the influence of dietary phosphate on a mouse mod...

AGU journal highlights -- Aug. 6, 2009

... summarized below are available at http://www.agu.org/jinstructions.shtml 1. Ozone depletion reduces ocean carbon uptake The Southern Ocean plays an important role in mitigating climate change because it acts as a sink of atmospheric carbon dioxide. Most current models predict that the strength ...

Joint research into an enzyme that causes genetic diseases

...knowledge of the structure of pyruvate carboxylase when it is in solution (in the "natural" state). Pyruvate carboxylase is a metabolic enzyme that plays a fundamental role in the metabolism of fatty acids (the components of fats) and sugars. When its function is not adequately performed (for example, w...

UC San Diego engineer provides insights to decades-old DNA squabble

...on of DNA and proteins that makes up chromosomes. The function of chromatin is to package DNA into a smaller volume to fit in the cell. Chromatin also plays an important role in the regulation of genetic processes like DNA replication, transcription, recombination, and repair because all these processes de...

'Microfluidic palette' may paint clearer picture of biological processes

...tial application of the microfluidic palette is the study of chemotaxis, the movement of cells along a chemical gradient, a biological phenomenon that plays a role in the spread of cancer (metastasis), wound healing, infection and carbon cycling in the ocean. ...

Little-known protein found to be key player

...N -- (July 29, 2009) -- Italian and U.S. biologists this week report that a little-understood protein previously implicated in a rare genetic disorder plays an unexpected and critical role in building and maintaining healthy cells. Even more surprising, their report in the journal Nature shows that the p...

Experimental treatment halts hypoxic-ischemic brain injury in newborns

...r in the divisions of Developmental Biology and Neurology at Cincinnati Children's. Besides demonstrating the brain's plasminogen activator system plays a pivotal role in neonatal cerebral hypoxic-ischemic brain injury, Dr. Kuan said the study also shows this system may be a promising therapeutic targe...

Scientists track impact of DNA damage in the developing brain

...e data will be important for understanding the role the DNA damage response plays in preventing neurological disease," the investigators wrote. The study ...ng to cell cycle arrest rather than apoptosis. In the hippocampus, which plays a role in memory and emotion, investigators reported abnormal gene expressi...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

...ereditary form of a rare neuroendocrine tumor called paraganglioma (PGL). The gene, called hSDH5, is required for activation of an enzyme complex that plays a critical role in the chemical reactions that take place within cells to convert biochemical energy into usable energy. This study will be published ...

Warming climate threatens California fruit and nut production

...t. Each species or cultivar is assumed to have a specific chilling requirement, which needs to be fulfilled every winter. Insufficient winter chill plays havoc with flowering time, which is particularly critical for trees such as walnuts and pistachios that depend on male and female flowering occurring ...

New research finds possible genetic link to cause of pregnancy loss and disorders

...sed mice to study the genetic causes of aneuploidy. They've zeroed in on mutations in a handful of genes as the culprits, including Bub1. The gene plays a role in a checkpoint that ensures that chromosomes are properly divided during meiosis, the cell division process that enables a stem cell to become...

UCLA researchers discover new molecular pathway for targeting cancer, disease

... found that specific gene expression induced by the Hh pathway could be inhibited. This finding was also confirmed in mice. "Since Hh signaling plays a major role in other physiological and pathological processes, we may be able to impact other diseases as well," Parhami said. Dr. William Matsui ...

The right messenger for a healthy immune response

... the Molecular Immunology group at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany have now shown that Beta-Interferon also plays a crucial role during an immune response: without Beta-Interferon immune cells are unable to show "wanted posters" of pathogens to other cells. As a c...

Flexible neck in cell-receptor DC-SIGN targets more pathogens

...ings from a research team led by University of Illinois chemist Deborah Leckband show that flexibility in the region near the binding sites of DC-SIGN plays a significant role in pathogen targeting and binding. "Our work focuses on how DC-SIGN recognizes HIV and other pathogens, and on what structural fe...
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Breaking Medicine News(10 mins):Health News:Less Sleep in Teen Years Tied to More Pounds at 21 2Health News:Flapping baby birds give clues to origin of flight 2Health News:Flapping baby birds give clues to origin of flight 3Health News:NJ Top Docs Presents Dr. Christophe Oliveira of Rehabilitation Instiute of North Jersey 2Health News:NJ Top Docs Presents Dr. Christophe Oliveira of Rehabilitation Instiute of North Jersey 3Health News:Drug shows promise against Sudan strain of Ebola in mice 2Health News:TGen receives approval for patient enrollment in brain cancer clinical trial 2
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