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PAP in Biological News

'Normal' cells far from cancer give nanosignals of trouble

...hnique, once optimized, could be used to detect cell abnormalities early and help physicians assess who might be at risk for developing cancer. Like a pap smear of the cervix, a simple brushing of cells is all that is needed to get the specimen required for testing. Using PWS, the researchers made ano...

Inherited genetic cause, possible treatment found for complex lung disorder

... events that lead to PAP. The lungs of people with pap fill with pulmonary surfactant, a substance compos... "This is the first data to demonstrate familial pap in humans and the critical role of the gene CSF2RA... anesthesia to flush out the lungs. People with pap can also acquire secondary infections. This happen...

NCI grant launches clinical trials for colon cancer screening

... screening test are negative in order to correlate the screening results with the colonoscopy results. "Our hope is that similar to how the routine pap smear drastically reduced deaths from cervical cancer, this new technology could do the same when it comes to colon cancer," said Backman. Backman'...

Women with AIDS face cervical cancer threat

...w-tech, low-cost screening protocol that allows them to identify precancerous or suspected cancer within minutes instead of waiting for results from a pap test. The women can then be treated immediately....

Iowa State researchers develop technology for early detection of viruses

...aser beam that lights the tags. Cameras capture the images for computer analysis. The research team tested the technique using samples from normal pap smears. They also spiked some of those samples with the virus to make sure the tests picked up known amounts of the virus. Although this test conce...

American Chemical Society's Weekly PressPac - Oct. 10, 2007

...when a sample has even a tiny amount of contaminants. Since over 50 million pap smears are performed in the United States each year to test for HPV the le...e, called single-molecule spectroscopy, could be easily integrated into the pap smear method. It can become a good clinical screening or quantification met...

Warts vaccine -- 1 of many in pipeline

...ould the product under trial be effective, it also gives them the chance to be amongst the first to benefit." A vaccine would complement both the pap smear program and currently available vaccines to prevent infections. Genital warts are transmitted by skin contact and the 2003 Australian Study...

Study shows continued success for new HPV vaccine against virus responsible for cervical cancer

...s cases and we were 98 percent effective. Everyone who gets cancer goes through a pre-cancerous stage," says Ault. "There are about 50 to 60 million pap smears performed each year in the US, and about seven percent are abnormal. We spend about 3 billion dollars each year to find and treat these pre-ca...

Synthetic peptide targets latent papilloma virus infections

...e skin, tongue or penis, warts in the cervix are often flat and easily overlooked unless laboratory staining is used to find signs of pathology, as in pap screening. If untreated or left to flare up repeatedly, the warts can progress to cancer. Earlier work by Botchan and numerous other researchers o...

New test for most virulent HPV strains under study

... a cervical scraping, like that for a liquid-based pap smear, to test for HPV types 16 and 18, responsibl...ay to 1,500 women age 30 and older with a negative pap test and to 1,000 women age 18 and older with cerv...“One is as a primary screening adjunct test with a pap test for women age 30 and older and the other is a...

Temple University Hospital investigates treatment for cervical dysplasia

... Hernandez. "Qualified participants must be 25 or younger, with an abnormal pap test result in the past six months." According to Hernandez, HPV vacci... Every year, more than 3 million women have an abnormal result on a routine pap test. Of these women, about 300,000-500,000 receive a diagnosis of moderat...

What does the public really know about HPV?

... could be sexually transmitted, and 79 percent knew it could cause abnormal pap smears. The public needs education about HPV and cervical cancer...sed health care choices among existing prevention strategies, including the pap test, HPV DNA test, and HPV vaccine, researchers concluded. "Individ...

Higher risk for cervical cancer seen among women infected with multiple HPV types

...een multiple HPV types and a woman's risk for developing pre-cancerous abnormalities in her cervix. During each of the 16,000 patient visits, both the pap smear and HPV tests were administered. The mean follow-up time of the study participants was over three years. When Franco, Trottier and their col...

Rutgers researchers find fat gene

...t; a simple single cell organism. "We isolated the pap enzyme from yeast that corresponds in form to lipi...t the sequence of the amino acids that make up the pap enzyme, allowing them to backtrack along the path ...ry much like the lipin found in mammals. The yeast pap enzyme shares a high resemblance to the lipin prot...

Survey reveals women and doctors aren't talking about HPV

...h their healthcare provider their HPV risk, get regular screenings with the pap test and, if they are age 30 or older, ask about HPV testing as well." O... cause cell changes in the cervix that can ultimately become cancerous. The pap test can identify cells that have become abnormal due to HPV, and HPV testi...

Study of genomic DNA leads to new advances in cancer diagnostics

...ential exists for future diagnostic applications. The cell smear assay, which is similar to methods commonly used in diagnostics laboratories (such as pap smears), could be applied to such a purpose. The authors also used flow cytometry to characterize melanomas of varying invasiveness. Further study wil...
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