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OHSU in Biological News

Genetically engineered mice yield clues to 'knocking out' cancer

...l in humans and mice. Therefore, a mouse serves a perfect model for studying the biological function of the neil1 gene in both species. To do this, ohsu researchers under R. Stephen Lloyd genetically engineered mice without the neil1 gene (known as neil1 knockout mice). During their first 6-10 months o...

OHSU researchers study the idling brain

...n have focused on how activity changes when engaged in specific tasks," explained Damien Fair, Ph.D., a postdoctoral research scientist in psychiatry, ohsu School of Medicine. "However now we know there are several regions in the brain that continue to interact while a person is supposedly at rest sort o...

Discovering drugs, biofuels in tropical seas

...s because the shipworm, one species of mollusk the ohsu project will focus on, harbors bacteria that hold ...sion of the Department of Science and Engineering, ohsu School of Medicine. The team includes scientists f...rman of the Department of Science and Engineering, ohsu School of Medicine. "Looking at microbes in the oc...

OHSU commercial collaborations have surged

...ome in fiscal year 2008 of nearly $10 million, the ohsu Office of Technology & Research Collaborations (TR...nsored research agreements cover projects on which ohsu plays a role, either through basic research or tes...an increasingly vibrant entrepreneurial culture at ohsu in which partnerships, such as one we've forged wi...

Methadone even at therapeutic levels can kill

...ociate professor of cardiovascular medicine in the ohsu School of Medicine. The findings lend support t...is fast-acting and its effect is long-lasting. The ohsu studys authors proposed that a large prospective e...piratory suppression both awake and asleep. The ohsu research was based on the work of the landmark Ore...

International scientists tackle obstacles to treating brain disorders

...he blood-brain barrier. He and 14 other scientists wrote the review. Edward Neuwelt, M.D., a professor of neurology and neurological surgery in the ohsu School of Medicine and a physician at the Portland Veterans Affairs Medical Center, is among the most active scientists in the international community...

OHSU researchers reveal the science of shivering

...ent by restricting blood flow to the skin, also appear to be controlled by the sensory mechanism that we found, explained Kazuhiro Nakamura, Ph.D., an ohsu Fellow for Research Abroad from the Japan Society for the Promotion of Science. He published the research along with his colleague Shaun Morrison, Ph....

Children with gene show reduced cognitive function

... University study has found. Scientists in the ohsu School of Medicine discovered that 7- to 10-year-o...or of behavioral neuroscience and neurology in the ohsu School of Medicine. "This study suggests there alr...nd colleagues - lead author Summer Acevedo, Ph.D., ohsu postdoctoral fellow, and Byung Park, Ph.D., senior...

OHSU turns innovations into commercial opportunities at record pace

...er year for Oregon Health & Science University. ohsu researchers disclosed 132 inventions, more than in... in 2000. Five new startup companies based on ohsu discoveries were incorporated during the year, bri...e from commercialization of inventions licensed by ohsu nearly doubled to $1.23 million from $719,800 the ...

OHSU surgeon implants donated tissue allografts

...professor of orthopedics and rehabilitation in the ohsu School of Medicine, and a specialist in sports med...Now, as a result of a new cooperative conceived by ohsu surgeons and administrators, Oregonians will incre...awford said the collaboration between CTS, JRF and ohsu "has been exciting and I am delighted I could be a...

OHSU lab finds meth receptor that could lead to therapy

...recently opened Program in Chemical Biology in the ohsu School of Medicine's Department of Physiology and ...r short. "The Program in Chemical Biology at ohsu is one of the few in the U.S. that allows biologis...es like drug addiction," said David Dawson, Ph.D., ohsu professor and chairman of physiology and pharmacol...

New cigarette designs don't offer lower predicted cancer risks

...tems at OHSU's OGI School of Science & Engineering, and a member of the ohsu Cancer Institute. "People have known for a long time that there are ca...professor of medicine (hematology and medical oncology) and director of the ohsu Cancer Institute, said "the tobacco industry would have us believe that the...

OHSU researchers demonstrate how white blood cells cannibalize virus-infected cells

...pointment in the Department of Molecular Microbiology and Immunology in the ohsu School of Medicine. "While we don't fully understand why this happens, ... Parker, Ph.D., a professor of Molecular Microbiology and Immunology in the ohsu School of Medicine. Parker and his colleague, Scott Wetzel, noted a similar...

Melatonin improves mood in winter depression

...kers, as well as in totally blind people. Lewy and his colleagues in the ohsu Sleep and Mood Disorders Lab set out to test the hypothesis that circadian ...e chairman of psychiatry, and director of the Sleep and Mood Disorders Lab, ohsu School of Medicine. ...

OHSU study says stem cell 'fusion' occurs in tumors

...ls to regenerate organ tissue. Scientists in the ohsu School of Medicine found that transplanted cells d...n the epithelial compartment of a tumor." Other ohsu studies in recent years are giving weight to the f...of molecular and medical genetics, and pediatrics, ohsu School of Medicine, and director of OHSU's Oregon ...

In-home sensors spot dementia signs in elderly

...y when elders are starting to have trouble. Hayes and colleagues in the ohsu Oregon Center for Aging & Technology - ORCATECH - used an unobtrusive "...d practice we have nowadays," said ORCATECH's director, Jeffrey Kaye, M.D., ohsu professor of neurology and biomedical engineering. ...

Clawed frog helps Fanconi anemia research make leaps

...ncer-susceptibility syndrome. Scientists in the ohsu School of Medicine's Department of Biochemistry an... Biology. The international team is led by the ohsu laboratory of Maureen Hoatlin, Ph.D. Using extract...s arrival on replicating DNA. Stacie Stone, an ohsu graduate student and co-lead author of the study, ...

OHSU discovery sheds light into how stem cells become brain cells

...and an adjunct associate professor of cell and developmental biology in the ohsu School of Medicine. "In later stages, these same stem cells suddenly start ...ith Dr. Steven Matsumoto from the Integrative Biosciences Department at the ohsu School of Dentistry, bred mice lacking the gene in the nervous system. This...

Male elephants woo females with precise chemistry

...ussen, Ph.D., research professor of environmental and biomolecular systems, ohsu OGI School of Science & Engineering, said of the study published in the...f of the enantiomer pair and identified as either "plus" or "minus." The ohsu and New Zealand team showed that the enantiomers of frontalin are released ...

Molecular Partners Required For Appropriate Neuronal Gene Repression

...professor of cell and developmental biology in the ohsu School of Medicine. "In recent years, it became cl... in our search for human treatments." Other key ohsu researchers involved in the study are: Stephen Bac...ciate professor of pediatrics and neurology in the ohsu School of Medicine; and Bruce Bebo Jr., Ph.D., a s...

OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis

...professor of cell and developmental biology in the ohsu School of Medicine. "In recent years, it became cl... in our search for human treatments." Other key ohsu researchers involved in the study are: Stephen Bac...ciate professor of pediatrics and neurology in the ohsu School of Medicine; and Bruce Bebo Jr., Ph.D., a s...

Researchers develop new testing methods for potential monkeypox or smallpox outbreak

...," said Mark Slifka, Ph.D., lead author and an assistant scientist at the VGTI, an assistant professor of molecular microbiology and immunology in the ohsu School of Medicine and an assistant scientist at the Oregon National Primate Research Center. "Our research demonstrates that the limitations of curre...

OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies

... pregnancy and also during infancy," explained Michael Gravett, M.D., chief of maternal-fetal medicine in the Department of Obstetrics and Gynecology, ohsu School of Medicine, and a researcher at ONPRC. "While we strongly encourage all women to quit smoking, this is not always possible. These data suggest...

Study: 'homemade' gene expression technology unreliable

...eter Spencer, Ph.D., professor of neurology in the ohsu School of Medicine. Spencer, director of the ohsu Center for Research on Occupational and Environmental Toxicology, co-authored with several ohsu colleagues one of three articles about microarrays...
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