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Neurologic in Biological News

Open access research celebrated

... 2008) http://ccforum.com/content/12/2/R61 This study explains how a common component of the contraceptive pill (progesterone) could improve the neurologic outcome for patients with severe head injuries. This year, three new awards were introduced: Editor of the Year - Chris Arme, Parasites & Vec...

Living long, living well

...ass.How does inflammation, brought on by stress, affect aging? What can we do to avert the looming public health and economic crisis of an epidemic of neurologic diseases caused by a rapidly expanding elderly population? How do older adults manage to keep a rosy outlook in the face of inevitable decline? How do...

To fight drug addiction, UB researchers target the brain with nanoparticles

...d the UB team. The new approach developed by the UB researchers also may be applicable to treating Parkinson's disease, cancer and a range of other neurologic and psychiatric disorders, which require certain drugs to be delivered to the brain. At the same time, the study's co-authors in the UB Department ...

Epstein-Barr virus may be associated with progression of MS

...searchers now are carrying out prospective longitudinal studies in patients who experienced a condition called "clinically isolated syndrome," a first neurologic episode that lasts at least 24 hours, and is caused by inflammation/demyelination in one or more sites in the central nervous system. If a second epis...

Mayo Clinic researchers suspect a novel gene is causing restless legs syndrome in a large family

...ng-Chi Lin, M.D., for help. Dr. Lin, a sleep disorders specialist at the Mayo Clinic campus in Florida, diagnosed restless legs syndrome. This common neurologic disorder interrupts sleep because of unpleasant sensations in the legs at rest, especially in the evening, that are temporarily relieved by movement. ...

Genetic mutation causes familial susceptibility for degenerative brain disease

...ore predisposes individuals to infection-triggered neurologic disease," said Dr. Neilson. "In order to prevent o...Dr. Neilson said. The disease is known for causing neurologic injury in children following common infections, li...e cough, vomiting and diarrhea in combination with neurologic dysfunction, alteration of consciousness and seizu...

NIH doles out $3M in new innovator awards to 2 UC San Diego faculty

... function of lipid molecules that transmit signals within cells. Despite the importance of these molecules in diseases ranging from cardiovascular and neurologic disease to diabetes and cancer, little is known about their functions. Field plans to study these seven lipid signaling molecules, called phosphoinosi...

Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering

... function of lipid molecules that transmit signals within cells. Despite the importance of this molecule in diseases ranging from cardiovascular and neurologic disease to diabetes and cancer, little is known about its function. The NIH doled out New Innovator Awards to a total of 31 young scientists acros...

UCSF researchers identify virus behind mysterious parrot disease

...searchers said. The disorder often leads to the birds' inability to swallow and digest food, with resulting wasting; many birds also suffer from neurologic symptoms such as imbalance and lack of coordination. Regardless of the clinical course the disease takes, it is often fatal. Scientists have theo...

N.Y. research team discovers how antidepressants and cocaine interact with brain cell targets

...so clear and detailed at the level of molecular behavior that they will be most valuable to developing more effective therapies for mood disorders and neurologic and psychiatric diseases, and to direct effective treatments for drug addiction to cocaine and amphetamines," says co-lead author Dr. Harel Weinstein,...

Weill Cornell science briefs June/July 2008

...at by understanding the mechanics of the cellular trafficking machine, he and other scientists will ultimately be able to identify and repair numerous neurologic malfunctions. News About Inflammatory Bowel Disease, Crohn's Disease: Stem Cells Heal Chronic Inflammation in the Gut May Help Restore Im...

New oral angiogenesis inhibitor offers potential nontoxic therapy for a wide range of cancers

...urprisingly wide range of cancers, including metastatic cancers, and produced a few complete remissions. Trials were suspended in the 1990s because of neurologic side effects that occasionally occurred at high doses, but it remains one of the broadest-spectrum angiogenesis inhibitors known. Lodamin appears ...

Gene therapy slows progression of fatal neurodegenerative disease in children

...that is fatal by age 8-12 years, was able to slow significantly the rate of neurologic decline in treated children, according to a paper published online ahead of...2 cDNA, the authors report that over an 18-month period, assessment using a neurologic rating scale demonstrated significant slowing of disease progression in the...

Motor neuron disease and toxic substances: Possible link?

...h on treatments. Most intriguing, the scientists found the mutations caused changes in a protein already known to be involved when people develop neurologic disorders as a result of exposure to toxic organophosphateschemicals commonly used in solvents and insecticides and also as nerve gas agents. This dis...

NIH awards UC $9 million grant to improve patient point-of-care technologies

...ssist the diagnosis and treatment of patients with neurologic emergencies. The result is the "Point-of-Care Cent... the project. Its said that time is brain during a neurologic emergency. Point-of-care information is critical f...iagnostic information for the patient experiencing neurologic emergencies. The UC center is dedicated to the...

Newly discovered antibody may be body's natural defense against Alzheimer's

...tes." The ability of the antibodies to recognize toxic proteins based on their shape may have important implications for immune therapy of other neurologic disorders, the researchers explain. "We were able to confirm that the antibodies we found not only recognize oligomers of beta amyloid but also ...

RNA map provides first comprehensive understanding of alternative splicing

...nome, the map has implications for the treatment of a growing list of human neurologic diseases in which RNA regulation, and particularly RNA splicing, has been i...Darnell. "There is a converging set of observations indicating that as neurologic diseases are better understood, alternative splicing is going to play an im...

Amateur boxing linked to brain cell injury

... a rest from boxing. At the first assessment, the boxers reported how many hits to the head they received during the match and underwent physical and neurologic examinations; none showed signs of brain injury. The researchers also tested the cerebrospinal fluids of 10 healthy men who were not boxers as contro...

Incidence of stroke decreases over last 50 years

...n 750,000 new strokes occurring each year in the United States. It is the third leading cause of death behind heart disease and cancer and the leading neurologic cause of long-term disability, according to background information in the article. Prior estimates of long-term trends in the incidence and severity o...

Green tea and the 'Asian Paradox'

...aging and preventing allergies, diabetes, bacterial and viral infections, cavities, reduce or cure diseases with an inflammatory component and improve neurologic and psychological health. "More studies are necessary to fully elucidate and better understand green tea's method of action, particularly at the ce...

Scientists show how thinking can harm brain cells

...ochester Medical Center have targeted a new culprit and method of attack on neurologic functions in diseases such as Alzheimer's and dementia associated with HIV....ation of memories, these impulses can inflict injury on neurons and disrupt neurologic function. Understanding this mechanism could provide a new path for drug...

Cells from amniotic fluid used to tissue-engineer a new trachea

...e-threatening: babies born with incomplete, malformed or missing tracheas cannot breathe and must immediately go on heart-lung bypass, which can cause neurologic and other complications. Surgeons have tried various fixes, such as grafting in pieces of the baby's rib or pelvic bone, using synthetic substances li...

Old drug shows new promise for Huntington's Disease

...Clioquinol is banned for internal use in many countries because of its side effects. In Japan in the late 1950s and 60s, the drug was found to cause a neurologic condition called subacute myelo-optico-neuropathy (SMON), with symptoms including visual loss, muscle weakness, and numbness, in several thousand peop...

Discovery could be key to bioterrorism defense

...es were put into cells that were then exposed to a live virus at AAHL." Hendra virus was first isolated in 1994 when an outbreak of respiratory and neurologic disease emerged among horses and humans in Hendra, Australia, killing two people. Hendra recently reemerged in Queensland, Australia, and researchers ...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

... and treatment is essential to preserving brain and motor function." Children transplanted after onset of symptoms do stabilize but exhibit minimal neurologic improvement, said Maria Luisa Escolar, MD, of UNC-CH, whose team assessed the neurological, cognitive and physical development of each child with Krab...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

... and treatment is essential to preserving brain and motor function." Children transplanted after onset of symptoms do stabilize but exhibit minimal neurologic improvement, said Maria Luisa Escolar, MD, of UNC-CH, whose team assessed the neurological, cognitive and physical development of each child with Krab...

Gene variations explain drug dose required to control seizures

... Similarly, appropriate doses of carbamazepine take time to determine because of the drug's variable affects on patient metabolism and its potential neurologic side effects. The team identified genes considered to be obvious candidates underlying patients' drug response, based on their known roles in the m...
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