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Nanoparticles in Biological News

Carbon nanoparticles toxic to adult fruit flies but benign to young

PROVIDENCE, R.I. [Brown University] Carbon nanoparticles are widely used in medicine, electronics, optics, materials science and architecture, but their health and environmental impact is not fully understood. In a series of experiments, researchers at Brown University sought to determine how ...

Facile synthesis of nanoparticles with multiple functions advanced in Singapore

Nanostructured materials have garnered great interest worldwide due to their unique size-dependent properties for chemical, electronic, structural, medical and consumer applications. Singapore's Institute for Bioengineering and Nanotechnology (IBN) has discovered a new environmentally friendly...

New nanoparticles could revolutionize therapeutic drug discovery

A revolutionary new protein stabilisation technique has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) which could lead to 30 per cent more proteins being available as potential targets for drug development - opening up exciting possibilit...

Magnetic nanoparticles navigate therapeutic genes through the body

Health professionals send genes and healthy cells on their way through the bloodstream so that they can, for example, repair tissue damage to arteries. But do they reach their destination in sufficient quantities? Scientists of the PTB have developed a highly sensitive measuring method with which ...

The gold standard: Biodesign Institute researchers use nanoparticles to make 3-D DNA nanotubes

Arizona State University researchers Hao Yan and Yan Liu imagine and assemble intricate structures on a scale almost unfathomably small. Their medium is the double-helical DNA molecule, a versatile building material offering near limitless construction potential. In the January 2, 2009 issue o...

UD researchers show that plants can accumulate nanoparticles in tissues

Researchers at the University of Delaware have provided what is believed to be the first experimental evidence that plants can take up nanoparticles and accumulate them in their tissues The laboratory study, which involved pumpkin plants, indicates a possible pathway for nanoparticles to enter ...

Workshop on environmental nanoparticles at UD, Nov. 10-11

The University of Delaware will host "Environmental Nanoparticles: Science, Ethics & Policy" on Nov. 10-11 at the John M. Clayton Hall Conference Center in Newark, Del. The registration deadline is Monday, Oct. 20. The workshop, which is co-sponsored by UD's Center for Critical Zone Research an...

$2M grant awarded to University of Kentucky for research on nanoparticles and human health

(Atlanta, Ga. August 20, 2008) Today, the U.S. Environmental Protection Agency (EPA) announced the award of a $2 million grant to the University of Kentucky (UK) to investigate how the sizes and shapes of nanoparticles affect their ability to enter the brain. This is the largest EPA Science to A...

New ORNL process brings nanoparticles into focus

OAK RIDGE, Tenn., June 23, 2008 Scientists can study the biological impacts of engineered nanomaterials on cells within the body with greater resolution than ever because of a procedure developed by researchers at the Department of Energy's Oak Ridge National Laboratory. The method, detailed i...

Environmental fate of nanoparticles depends on properties of water carrying them

The fate of carbon-based nanoparticles spilled into groundwater and the ability of municipal filtration systems to remove the nanoparticles from drinking water depend on subtle differences in the solution properties of the water carrying the particles, a new study has found. In slightly sal...

MIT: Remote-control nanoparticles deliver drugs directly into tumors

CAMBRIDGE, MA--MIT scientists have devised remotely controlled nanoparticles that, when pulsed with an electromagnetic field, release drugs to attack tumors. The innovation, reported in the Nov. 15 online issue of Advanced Materials, could lead to the improved diagnosis and targeted treatment of c...

New insights into health and environmental effects of carbon nanoparticles

A new study raises the possibility that flies and other insects that encounter nanomaterial "hot spots," or spills, near manufacturing facilities in the future could pick up and transport nanoparticles on their bodies, transferring the particles to other flies or habitats in the environment. The s...

University of Leicester researchers discover new fluorescent silicon nanoparticles

Researchers in the Department of Physics and Astronomy at the University of Leicester have developed a new synthesis method, which has led them to the discovery of fluorescent silicon nanoparticles and may ultimately help track the uptake of drugs by the body's cells. Dr Klaus von Haeften expla...

Shape matters in the case of cobalt nanoparticles

Shape is turning out to be a particularly important feature of some commercially important nanoparticlesbut in subtle ways. New studies* by scientists at the National Institute for Standards and Technology (NIST) show that changing the shape of cobalt nanoparticles from spherical to cubic can fund...

To fight drug addiction, UB researchers target the brain with nanoparticles

BUFFALO, N.Y. -- A precise, new nanotechnology treatment for drug addiction may be on the horizon as the result of research conducted at the University at Buffalo. Scientists in UB's Institute for Lasers, Photonics and Biophotonics and UB's Department of Medicine have developed a stable nanoparti...

MU scientists go green with gold, distribute environmentally friendly nanoparticles

COLUMBIA, Mo. -- Gold nanoparticles are everywhere. They are used in cancer treatments, automobile sensors, cell phones, blood sugar monitors and hydrogen gas production. However, until recently, scientists couldn't create the nanoparticles without producing synthetic chemicals that had negative i...

Researchers mimic bacteria to produce magnetic nanoparticles

When it comes to designing something, its hard to find a better source of inspiration than Mother Nature. Using that principle, a diverse, interdisciplinary group of researchers at the U.S. Department of Energys Ames Laboratory is mimicking bacteria to synthesize magnetic nanoparticles that could...

Novel 3-D cell culture model shows selective tumor uptake of nanoparticles

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists. The project, conducted jointly in the Schools of Pharmacy, Biomedical Sciences and Human Development, will b...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

Researchers at Purdue University have shown that common bacteria can deliver a valuable cargo of "smart nanoparticles" into a cell to precisely position sensors, drugs or DNA for the early diagnosis and treatment of various diseases. The approach represents a potential way to overcome hurdles ...

Cancer tip -- Nanoparticles can damage DNA, increase cancer risk

Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research presented at the 2007 Annual Meeting of the American Association for Cancer Research. Nanoparticles are small enough to penetrate cell ...

Coated nanoparticles solve sticky drug-delivery problem

The layers of mucus that protect sensitive tissue throughout the body have an undesirable side effect: they can also keep helpful medications away. To overcome this hurdle, Johns Hopkins researchers have found a way to coat nanoparticles with a chemical that helps them slip through this sticky barr...

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

Researchers at UC San Diego have discovered that iron-containing nanoparticles being tested for use in several biomedical applications can be toxic to nerve cells and interfere with the formation of their signal-transmitting extensions. "Iron is an essential nutrient for mammals and most life f...

Gold nanoparticles prove to be hot stuff

Gold nanoparticles are highly efficient and sensitive "handles" for biological molecules being manipulated and tracked by lasers, but they also can heat up fast--by tens of degrees in just a few nanoseconds--which could either damage the molecules or help study them, according to scientists at JILA...

U-M researchers use nanoparticles to target brain cancer

Tiny particles one-billionth of a meter in size can be loaded with high concentrations of drugs designed to kill brain cancer. What's more, these nanoparticles can be used to image and track tumors as well as destroy them, according to researchers at the University of Michigan Comprehensive Cancer ...

Quantum dots reviewed -- Could these nanoparticles hold the cure to cancer?

The worlds of medical and biological research are abuzz with the promises offered by nanoparticles known as semiconductor quantum dots. These Quantum Dots (QDs) have unique optical and electronic properties that make them suitable for breakthrough treatments such as the detection and destructio...

MIT nanoparticles may help detect, treat tumors

A new technique devised by MIT engineers may one day help physicians detect cancerous tumors during early stages of growth. The technique allows nanoparticles to group together inside cancerous tumors, creating masses with enough of a magnetic signal to be detectable by a magnetic resonance imagi...

Gold nanoparticles could improve antisense cancer drugs

In the fight against cancer, antisense drugs, which prevent genes from producing harmful proteins such as those that cause cancer, have the promise to be more effective than conventional drugs, but the pace of development of these new drugs has been slow. Using gold nanoparticles combined with DN...

NJIT study shows nanoparticles could damage plant life

A nanoparticle commonly used in industry could have a damaging effect on plant life, according to a report by an environmental scientist at New Jersey Institute of Technology (NJIT). The report, published in a recent issue of "Toxicology Letters," shows that nanoparticles of alumina (aluminum ox...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

A novel delivery system that transports gene silencing nanoparticles into tumor cells has been shown to inhibit Ewing's sarcoma in an animal model of the disease. In this classic "Trojan horse" approach, a protein called transferrin that normally delivers iron into cells is modified to also smug...

In nature, proteins sweep up nanoparticles

Here’s a pollution-control tip from nature: Deep inside a flooded mine in Wisconsin, scientists from several institutions including the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have discovered a world in which bacteria emit proteins that sweep up metal nanop...

Argonne to showcase science and technology at community open house

..., science and supercomputers work together in solving logic puzzles Learn about the science of toys Walk through an accelerator Glimpse nanoparticles changing colors Battle model cars powered by fuel cells to see which is fastest Watch a master scientific glassblower demonstrate his craft ...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

...anoparticle delivery of a DNA encoding diphtheria toxin suicide gene. These nanoparticles were injected into mice with primary or metastatic ovarian tumors. To t... grow at all, while all control tumors increased in size. Administration of nanoparticles to three different ovarian cancer mouse models prolonged lifespan by nearly...

All-in-1 nanoparticle: A Swiss Army knife for nanomedicine

... nanoparticles are being developed to perform a wide range of med... at the University of Washington have combined two nanoparticles in one tiny package. The result is the first st...s is the first time that a semiconductor and metal nanoparticles have been combined in a way that preserves the fun...

DOE-funded research projects win 46 R&D 100 Awards for 2009

...coln, Neb. (Jointly with the Environmental Protection Agency) Precision nanoparticles A revolutionary technology that efficiently produces nanoparticles in uniform and prescribed sizes (1-100 nanometers) using supercritical flui...

Chasing tiny vehicles

... nanoparticles are just billionths of a millimeter in size. Exhib...nsitive microscopic technique to pursue individual nanoparticles as they make their way into target cells in real-...tial and temporal resolution. They tested magnetic nanoparticles that could be used, among other things, in cancer ...

Toxin detection as close as an inkjet printer

... like the one found in computer printer cartridges but with special additives to make the ink biocompatible. An ink comprised of biocompatible silica nanoparticles is first deposited on paper, followed by a second ink containing the enzyme, and the resulting bio-ink forms a thin film of enzyme that is entrapped i...

Contaminated site remediation: Are nanomaterials the answer?

... http://www.nanotec.org.uk/finalReport.htm ), the British Royal Society and Royal Academy of Engineering recommended that the use of free manufactured nanoparticles be prohibited for environmental applications such as remediation until further research on potential risks and benefits had been conducted. The Europe...

New way to make sensors that detect toxic chemicals

...the chips. According to Morris, this is the first time that nickel oxide nanoparticles have been applied in this way. But to Beach, the most important "first" ...nstance, to speed up the response rate. A one-gram batch of nickel oxide nanoparticles costs about $5.00 to make; one chip carries four nanograms (billionths of a...

Canadian researchers set to study impact of nanomaterials on aquatic ecosystems

...rsity of Alberta and the National Research Council of Canada, will collaborate on a $3.39 million, three-year study to assess the potential effects of nanoparticles in specific water environments. "Nanotechnology is a very new and quickly developing field. Governments and regulating agencies around the world ...

Can a new implant coating technique create a new six million dollar man?

... "We can incorporate biological materials" because the electrochemical process works at lower temperatures, says Prof. Eliaz. "The reinforcement of nanoparticles will improve the mechanical properties and may also improve the biological response. Drug incorporation may reduce the risk of post-surgery infection ...
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