NYU in Biological News

$29.4 million grant establishes CTSI at NYU in partnership with Health and Hospitals Corporation

New York, NY July 14, 2009 NYU and NYU School of Medicine received a $29.4 million, five-year Clinical and Translational Science Award from the National Institutes of Health (NIH) to establish a University-wide Clinical & Translational Science Institute (CTSI) in partnership with the New York Ci...

From stem cells to new organs: Stanford and NYU scientists cross threshold in regenerative medicine

By now, most people have read stories about how to "grow your own organs" using stem cells is just a breakthrough away. Despite the hype, this breakthrough has been elusive. A new report published in the March 2009 issue of The FASEB Journal ( http://www.fasebj.org ) brings bioengineered organs ...

A new cellular pathway linked to cancer is identified by NYU researchers

NEW YORK, July 24, 2008 In the life of a cell, the response to DNA damage determines whether the cell is fated to pause and repair itself, commit suicide, or grow uncontrollably, a route leading to cancer. In a new study, published in the July 25th issue of Cell , scientists at NYU Langone Medic...

Hybridization partially restores vision in cavefish, NYU study finds

Hybridizing blind cave fish from different cave populations can partially restore the vision of their offspring, biologists at New York University have found. The study suggests that genetic engineering can override, at least in part, half a million years of evolutionary change in one generation. ...

NYU Langone Medical Center awarded NIH grants totaling $1,560,000

... New York, NY, June 24, 2009 Two nyu Langone Medical Center researchers have received $1,560,000 in grant suppor...om the National Institutes of Health (NIH). The studies being conducted at nyu Langone Medical Center are two of several projects being conducted through ...

Genetic switch potential key to new class of antibiotics

...s much more than a passive middleman, and instead exerts decisive control over expression. Researchers in the Breaker lab at Yale and Nudler lab at nyu reported in 2002 that regulatory mechanisms arising from riboswitches regulate gene expression at the level of the mRNA by changing shape in ways that...

NYU College of Dentistry awarded $1.9 million NIH grant for HIV research

...discovered the mechanism in an earlier study he conducted with the assistance of a one-year pilot grant from CFAR, The Center for AIDS Research at the nyu School of Medicine. HIV normally inserts its DNA into the DNA of the cells it infects in a process called integration that is inefficient and pron...

New potential therapeutic target discovered for genetic disorder -- Barth syndrome

... Researchers at nyu Langone Medical Center may have discovered a new t...e study and assistant professor of cell biology at nyu Langone Medical Center. BTHS syndrome is an X-...f organic acids in urine. In a previous study, nyu researchers documented the characteristics of a ta...

NYU Langone Medical Center researchers find micro RNA plays a key role in melanoma metastasis

...tant to therapy, and deadly. Now, scientists from nyu Langone Medical Center have identified the possibl...istant professor in the Department of Pathology at nyu School of Medicine, and the lead author of the study. Dr. Hernando is also a member of the nyu Cancer Institute at...

Consumers desire more genetic testing, but not designer babies

... A new study by researchers at nyu Langone Medical Center found a high desire for add...away, MS CGC, a certified genetic counselor at the nyu Cancer Institute. The article entitled, "Consumers...arry Ostrer, Director of Human Genetics Program at nyu Langone Medical Center. "Our study gauged the cons...

JCI online early table of contents: Jan. 19, 2009

...ettering Cancer Center, New York, New York, USA. Phone: (212) 639-7333; Fax: (212) 794-6236; E-mail: f-giancotti@ski.mskcc.org . Yuliya Pylayeva nyu School of Medicine, New York, New York, USA. Phone: (212) 263-2937; Fax: (212) 263-8166; E-mail: pylayy01@nyumc.org . View the PDF of this articl...

David Rose to present Howe School lecture on new technologies and business models, Jan. 29

...ring high-potential entrepreneurs who are breaking new ground in technology-enabled businesses. He is a regular speaker at Yale, Harvard, Columbia and nyu business schools, and was a founding member of the New York New Media Association. Rose is one of the country's most active early-stage technology i...

NYU scientists discover dangerous new method for bacterial toxin transfer

...than previously imagined. In a laboratory experiment, the scientists from nyu School of Medicine discovered that Staphylococcus aureus, a notorious bacte...ing microbes. When they modeled that phage therapy in the lab, however, the nyu researchers observed a phage-mediated transfer of pathogenic S. aureus gene...

Peering inside the skull of a mouse to solve meningitis mystery

... NEW YORK, Dec. 22, 2008 nyu Langone Medical Center scientists and their collab...n immune system responds to viral diseases. The nyu researchers, Michael L. Dustin, Ph.D., the Irene D...fessor of Immunology and Professor of Pathology at nyu School of Medicine, and Jiyun V. Kim, Ph.D., a sci...

Ants may help researchers unlock mysteries of human aging process

... nyu School of Medicine researcher Dr. Danny Reinberg w...," said Dr. Reinberg, professor of Biochemistry at nyu School of Medicine's Smilow Research Center. "Ants...is a Howard Hughes Medical Institute researcher at nyu and lead investigator for the award. Dr. Reinberg ...

NYU receives $490k NSF grant to promote women in the sciences

...ce. "This grant is a small step towards helping nyu accelerate the necessary institutional transformat..., faculty excellence is significantly enhanced and nyu becomes a stronger institution." "Given its ris...f and deputy to the president, who also chairs the nyu Women's Leadership Forum, launched last year with ...

NYU Cancer Institute researcher among first NIH EUREKA award recipients

...ard, Ph.D, assistant professor of pathology at the nyu Cancer Institute, is the first nyu School of Medicine recipient of the EUREKA award. In 2006, Dr. Krogsgaard joined nyu and her work has focused on the different signalin...

NYU, American Museum of Natural History receive $1.6 million NSF grant

...ers to embark on genome-wide structure predictions in a cost effective way. nyu biologists, headed by Bonneau, who holds an appointment in NYU's Courant In...hese protein sequences. These methods include "Rosetta," a computer program nyu researchers have previously used in predicting protein structure. Thes...

NYU scientists identify critical protein complex in formation of cell cilia

...ORK, August 19, 2008 An international team led by nyu Cancer Institute have identified a protein complex...cht, Ph.D., professor of pathology and director of nyu Cancer Institute Genomics Facility, investigates t...h in humans," said William Y. Tsang, Ph.D., of the nyu School of Medicine and Cancer Institute, and first...

NYU Langone Medical Center's tip sheet to the International Conference on Alzheimer's Disease 2008

... NEW YORK, July 26, 2008 nyu Langone Medical Center researchers have long been ...egivers' depression. At the 2008 ICAD meeting, nyu Langone Medical Center researchers are presenting ...D., Associate Professor, Department of Psychiatry, nyu Langone Medical Center EMBARGOED FOR RELEASE UNT...

Asthma and other allergies tied to absence of specialized cells

...g an allergic reaction. Now, researchers at nyu School of Medicine have zeroed in on a class of cu...e Lafaille, Ph.D., Associate Research Scientist at nyu Langone Medical Center. "Every time we don't reac...allergens, which are always protein molecules. The nyu research shows that Foxp3-directed regulatory T ce...

Landon Foundation-AACR INNOVATOR Awards

...arbone, M.D., Ph.D., and Haining Yang, Ph.D., University of Hawaii; Nancy Cox, Ph.D., and Ian Steele, Ph.D., University of Chicago; Harvey Pass, M.D., nyu School of Medicine and Clinical Cancer Center; Joseph Testa, Ph.D., Fox Chase Cancer Center; Y. Izzetin Baris, M.D., University of Hacettepe in Ankara...

NYU dental professor discovers biological clock linking tooth growth to other metabolic processes

...time intervals for small mammals, and longer ones for larger animals. For example, rats have a one-day interval, chimpanzees six, and humans eight. nyu dental professor Dr. Timothy Bromage discovered the rhythm while observing incremental growth lines in tooth enamel, which appear much like the annual...

Scientists find color vision system independent of motion detection

...el pathways. More recently, however, the complete segregation of motion detection and color vision came into question. To explore this matter, the nyu and University of Wrzburg researchers examined the fruit fly Drosophila. Fruit flies development is well-understood by biologists and therefore serves...

Evolution is deterministic, not random, biologists conclude from multi-species study

...ent Biology. The leading author is Karin Kiontke, a post-doctoral fellow in New York Universitys Department of Biology. The research team included nyu Biology Professor David Fitch as well as researchers from the University of Paris, the Israel Institute of Technology, and the Max-Planck Institute fo...

A novel way found to prevent protein plaques implicated in Alzheimer's

...Ph.D., Professor of Psychiatry and Cell Biology at nyu School of Medicine and Director of the Center for ...r. Nixon also directs the Silberstein Institute at nyu School of Medicine. Given the increasing prev...Child and Adolescent Psychiatry and a Vice-Dean at nyu School of Medicine. ...

NYU's Center for Genomics & Systems Biology receives $4.4 million NSF grant

...as received a $4.4 million National Science Foundation (NSF) grant in which nyu researchers will seek to identify genes on a genome-wide scale that underli...othy Schiff Professor of Genomics and the projects primary investigator. nyu is the grants lead institution, with scientific collaborations coming from ...

Vaccine prevents prion disease in mice

... days for mice that have not been vaccinated to develop the disease. "These are promising findings," said study author Thomas Wisniewski, MD, of nyu School of Medicine in New York, and a member of the American Academy of Neurology. "We are now in the process of redesigning the vaccine so it can be ...

NYU algorithm enhances ability to detect cancer genes

...mor suppressor genes implicated in the cancer. The nyu study focused on automatic methods for reliable de...tions, and their boundaries. For this purpose, the nyu scientists sought to devise an efficient and novel...the cancer progresses to an advanced stage. The nyu algorithm estimates the location of tumor suppress...

NYU researchers decorate virus particles, showing potential to enhance MRI capabilities

...tly by NYU's Department of Chemistry and the Department of Radiology at the nyu School of Medicine. The study is part of a collaborative discussion group b...uch as those for both MR and optical imaging, are integrated. The nyu researchers were able to show the attachment of a large number of gadoliniu...

Study finds how organs monitor themselves during early development

... growing and developing normally, and if it needs to regenerate itself. When such loops derail, cancer and other diseases can arise. Scientists at nyu School of Medicine have unraveled the signals in a feedback loop governing ovarian development. This work has been several years in the making and is ...

Biologists develop genome-wide map of miRNA-mRNA interactions

...are predicted miRNA targets. To test the computational predictions, the nyu team developed a new in vivo analysis system comparing the expression of a ...u) and are linked to a new graphical network-browsing tool developed in the nyu Center for Comparative Functional Genomics. This allows for exploration of ...

Researchers show how air pollution can cause heart disease

... "We established a causal link between air pollution and atherosclerosis," says Lung Chi Chen, Ph.D., Associate Professor of Environmental Medicine at nyu School of Medicine and a lead author of the study. Atherosclerosis--the hardening, narrowing, and clogging of the arteries--is an important component ...

Scientists observe how a close bond activates the immune system

...ffect on T cell signaling," says Michael L. Dustin, Ph.D., the Irene Diamond Associate Professor of Immunology and Associate Professor of Pathology at nyu School of Medicine, and one of the lead authors of the study. The research by Dr. Dustin and Jay T. Groves of University of California, Berkeley, a...

Scientists discover the molecular switch for nerve cells' insulating jelly rolls

...by James L. Salzer, M.D., Ph.D., Professor of Cell Biology and Neurology at nyu School of Medicine, identified the long-sought factor that determines wheth...es of experiments, Dr. Carla Taveggia, the first author of the study and an nyu research scientist, together with collaborators at NYU, Columbia University...

NYU chemists use computer simulation to enhance understanding of DNA transcription

...s regulate fundamental gene expression. However, the molecular mechanism underlying this process remains unclear. The research team, which included nyu chemists Tamar Schlick, Jian Sun (now at the Cornell Medical School), and Qing Zhang, analyzed a 12-nucleosome array. Using a variety of salt conditio...

Active Vaccine Prevents Mice From Developing Prion Disease

... nyu School of Medicine scientists have created the fir... and Europe are working on prion vaccines. But the nyu study is important because it breaks new ground in...ve immunization. The prion vaccine developed at nyu would most likely first be used to protect livesto...

Researchers find new genes necessary to make embryo

...m the analyses of genes showing partial penetrance suggest the possibility of a general architectural motif in genetic networks," said Fabio Piano, an nyu biologist and lead author of the study, "in which genes in critical positions consist largely of older components while new functions added later prov...

NYU study reveals how brain's immune system fights viral encephalitis

... "There is no magic bullet in fighting viral infections in neurons," said nyu Biology Professor Carol Shoshkes Reiss, the study's senior author. "However...as been responsible for a viral encephalitis outbreak in the northeast. The nyu researchers set out to determine how the body can fight viral encephalitis....

NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis

... "There is no magic bullet in fighting viral infections in neurons," said nyu Biology Professor Carol Shoshkes Reiss, the study's senior author. "However...as been responsible for a viral encephalitis outbreak in the northeast. The nyu researchers set out to determine how the body can fight viral encephalitis....