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Facile synthesis of nanoparticles with multiple functions advanced in Singapore

Nanostructured materials have garnered great interest worldwide due to their unique size-dependent properties for chemical, electronic, structural, medical and consumer applications. Singapore's Institute for Bioengineering and Nanotechnology (IBN) has discovered a new environmentally friendly...

Trans fats hinder multiple steps in blood flow regulation pathways

CHAMPAIGN, Ill. Partially hydrogenated vegetable oils in processed foods contain trans fatty acids that interfere with the regulation of blood flow. A new report reveals a new way in which these "trans fats" gum up the cellular machinery that keeps blood moving through arteries and veins. In t...

Tracking down the causes of multiple sclerosis

This release is available in German . Over 100,000 people suffer from multiple sclerosis in Germany alone. Despite intensive research, the factors that trigger the disease and influence its progress remain unclear. Scientists from the Max Planck Institute of Neurobiology in Martinsried an...

Mothers of multiple births at increased odds of postpartum depression

Mothers of multiples have 43 percent increased odds of having moderate to severe depressive symptoms nine months after giving birth compared to mothers of single-born children, according to researchers at the Johns Hopkins Bloomberg School of Public Health. Researchers examined the relationship be...

New drug agent knocks out multiple enzymes in cancer pathway

A team of 24 researchers from the U.S., Europe, Taiwan and Japan and led by University of Illinois scientists has engineered a new anti-cancer agent that is about 200 times more active in killing tumor cells than similar drugs used in recent clinical trials. The study appears this week in the ...

'Buckyballs' to treat multiple sclerosis

If you're of a certain age, you'll remember Buckminster Fuller's distinctive "geodesic domes" soccer-ball-shaped structures that the late futurist envisioned as ideal human domiciles. Tel Aviv University chemists remember them too and are now putting them to use in the treatment of multiple scle...

Malaria immunity trigger found for multiple mosquito species

Researchers at the Johns Hopkins Bloomberg School of Public Health have for the first time identified a molecular pathway that triggers an immune response in multiple mosquito species capable of stopping the development of Plasmodium falciparum -the parasite that causes malaria in humans. By s...

Acorda Therapeutics submits new drug application for Fampridine-SR in multiple sclerosis

HAWTHORNE, N.Y., February 2, 2009 Acorda Therapeutics, Inc. (Nasdaq: ACOR) today announced the submission of a New Drug Application to the U.S. Food and Drug Administration (FDA) on January 30, 2009 for Fampridine-SR, a novel therapy being developed to improve walking ability in people with multi...

Response to immune protein determines pathology of multiple sclerosis

New research may help reveal why different parts of the brain can come under attack in patients with multiple sclerosis (MS). According to a new study in mice with an MS-like disease, the brain's response to a protein produced by invading T cells dictates whether it's the spinal cord or cerebellum...

Project aims to reduce complications, multiple surgeries with biodegradable implantable devices

PITTSBURGHDozens of engineers and doctors from universities and industries around the world will collaborate on a five-year, $18.5 million project announced Sept. 4 to develop implantable devices made from biodegradable metals. The devices will be designed to adapt to physical changes in a patient...

Fast AFM probes measure multiple properties of biomolecules or materials simultaneously

New research demonstrates that novel probe technology based on flexible membranes can replace conventional atomic force microscopy (AFM) cantilevers for applications such as fast topographic imaging, quantitative material characterization and single molecule mechanics measurements. In addition ...

Potential new target for multiple sclerosis therapy

Researchers demonstrate both genetic and pharmaceutical evidence for the role of a protein called collagenase-2 in the development of multiple sclerosis (MS), providing a potential new way to combat this debilitating disease. Collagenase-2 is a member of a protein family called matrix metallop...

New magnetic separation technique might detect multiple pathogens at once

DURHAM, N.C. -- A magnetic separation technique developed by researchers at Duke University's Pratt School of Engineering and Purdue University makes it relatively simple to sort through beads hundreds of times smaller than the period at the end of this sentence. The method could lead to new t...

Israeli scientists identify: Genes that affect responses of multiple sclerosis patients to copaxone

A group of Israeli scientists from the Technion Israel Institute of Technology, the Weizmann Institute of Science and Teva Pharmaceutical Industries have recently identified genes responsible for the positive response of many multiple sclerosis patients to the drug Copaxone®. These findings m...

For honey bee queens, multiple mating makes a difference

The success of the reign of a honey bee queen appears to be determined to a large degree by the number of times she mates with drone bees. That is what research by scientists in the Department of Entomology and W.M. Keck Center for Behavioral Biology at North Carolina State University suggests...

Emphasis on conifer forests places multiple species at risk

CORVALLIS, Ore. The traditional emphasis on dense, fast-growing, conifer-dominated forests in the Pacific Northwest raises questions about the health of dozens of animal species that depend on shrubs, herbs and broad-leaf trees, a new analysis by Oregon State University and the U.S. Geological Su...

Nicotinic receptors may be important targets for treatment of multiple addictions

For years, scientists have known that some people are biologically more susceptible to drug addiction than others, but they have only been able to speculate why. In the August 15, 2007 issue of the Journal of Neuroscience, researchers at the University of Chicago report on a study that may help...

Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma

Two new studies may lead to the development of more effective therapies for individuals with multiple myeloma (MM), a common and incurable blood cell cancer. The research, published by Cell Press in the August issue of the journal Cancer Cell, provides new insight into the molecular mechanisms tha...

Investigating the measles virus as a tool to kill multiple myeloma

Mayo Clinic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow that currently has no cure. This is the third of a series of molecular medicine studies in patients testing the potential of measles to kill ca...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

Human embryonic stem cells (hESCs) hold great promise for benefiting degenerative diseases, and do so by invoking multiple mechanisms. Such cells can be grown in a manner compatible with clinical use (i.e., without animal feeder layers) and even without the need for immunosuppression. These were a ...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

Researchers in the Greene Infectious Disease Laboratory at Columbia University Mailman School of Public Health and their colleagues in the WHO Global Laboratory Network have developed a new tool for pathogen surveillance and discovery—the GreeneChip System. The GreeneChip is the first tool to prov...

An advanced genetic diagnostic method for multiple myeloma

A researcher at the University of Navarra, Borja Sáez Ochoa, has proposed a new genetic diagnostic method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages. The dissertation of this biologist, produced in the Department of Genet...

Epstein-Barr virus might kick-start multiple sclerosis

Researchers have found that patients with multiple sclerosis (MS) carry a population of immune cells that overreact to Epstein-Barr virus. The virus, which causes mononucleosis and may contribute to some cancers, has long been suspected to play a role in MS. However, the mechanism linking the virus...

Higher risk for cervical cancer seen among women infected with multiple HPV types

Although doctors have known that the cervical tissue at the opening to the womb can harbor multiple HPV types, this study is the first to document that the risk for developing cervical cancer, the second most common form of cancer in women worldwide, is higher in females infected with multiple HPV ...

Airborne mold spores increase kids' risk for multiple allergies

University of Cincinnati (UC) researchers say exposure to a certain group of fungal spores--abundant in the air that we breathe every day--can make young children more susceptible to developing multiple allergies later in life. The team found that infants who were exposed to basidiospores and ot...

Chimpanzees can transmit cultural behavior to multiple 'generations'

Transferring knowledge through a chain of generations is a behavior not exclusive to humans, according to new findings by researchers at the Yerkes National Primate Research Center of Emory University and the University of St. Andrews, Scotland. For the first time, researchers have shown chimpanzee...

Epstein-Barr virus may be associated with multiple sclerosis

Young adults with high levels of antibodies against the Epstein-Barr virus, the virus that most often causes mononucleosis, may be more likely to develop multiple sclerosis 15 to 20 years later, according to a study posted online today that will appear in the June 2006 print issue of Archives of Ne...

Genome changes tracked during multiple myeloma initiation, progression and treatment

Scientists have made significant progress toward elucidating key genetic events associated with the development and progression of multiple myeloma (MM), an incurable malignancy that is the second most common cancer of the blood. The results, published in the April issue of Cancer Cell, provide new...

Compound from marine bacteria shows potential as multiple myeloma therapy

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November is...

OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis

Oregon Health & Science University researchers have identified some of the key factors that prevent the repair of brain damage caused by multiple sclerosis (MS), complications of premature birth, and other diseases and conditions. The findings offer important clues about why the nervous system ...

New technique helps identify multiple DNA regulatory sites

Just as the printing press revolutionized the creation of reading matter, a "nano-printing" technique developed at MIT could enable the mass production of nano-devices currently built one at a time. The most immediate candidate for this innovation is the DNA microarray, a nano-device used to dia...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

Multiple sclerosis (MS) can be an unpredictable disease. It develops when the body's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vision—that can appear independe...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of...

Scientists find universal rules for food-web stability

..."Food-web stability is enhanced when species at high trophic levels feed on multiple prey species and species at intermediate trophic levels are fed upon by multiple predator species," says Ulf Dieckmann of IIASA. The scientists have also...

AGU journal highlights -- Aug. 6, 2009

...e studies but that it is not feasible to impose them in a common way across multiple models for the next Intergovernmental Panel on Climate Change assessment. ...r situations with closely spaced bottom topography. Title: Influence of multiple sills upon internal wave generation and the implications for mixing Auth...

Understanding how weeds are resistant to herbicides

...ere and independently down in southern Illinois?" Understanding how the resistance occurred has implications for weed management. "If it's evolving multiple times, you need to pay attention to what you're doing in your field whereas if it evolved once and is moving around then you've got to pay attention t...

Brain difference in psychopaths identified

...n Molecular Psychiatry . The research investigated the brain biology of psychopaths with convictions that included attempted murder, manslaughter, multiple rape with strangulation and false imprisonment. Using a powerful imaging technique (DT-MRI) the researchers have highlighted biological differences in...

DNA computation gets logical at the Weizmann Institute of Science

...(Socrates is a man), the computer answered the question 'Is Socrates Mortal?' correctly. The team went on to set up more complicated queries involving multiple rules and facts, and the DNA computing devices were able to deduce the correct answers every time. At the same time, the team created a compiler a...

August 2009 Geology and GSA Today media highlights

... period in which southern Pangea saw the waxing and waning of massive continental ice sheets while low-latitude Pangean sedimentary sequences recorded multiple 100-m eustatic fluctuations. This cyclicity is thought to have been driven by changes in Earth's orbit with relation to the sun. Horton and Poulsen em...

Parasites ready to jump

...the endo-siRNAs. Furthermore, the team pinpointed an entirely novel feature of this system: Repression of transposon activity was also detectable when multiple copies of a mobile element were present in the cell but not yet incorporated into the genome. The phenomenon of RNA interference first came to ligh...
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