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Methods in Biological News

K-State host to workshop on rapid methods to detect microorganisms in food

Kansas State University once again is host to a noted microbiology workshop that helps the scientists who test food and other samples for microorganisms. K-State's 29th annual Rapid Methods and Automation in Microbiology workshop will be June 19-26. The workshop, now in its 29th year, has serve...

Scholar unconvinced new lie-detection methods better than old ones

CHAMPAIGN, lll. When a crime has been committed, the usual modus operandi for police detectives and their fictional counterparts has been to dust the scene for fingerprints. And once they have a suspect in custody, out comes the polygraph, or lie detector. But in today's forensically sophistic...

Protein function and chromatin structure methods featured in Cold Spring Harbor Protocols

COLD SPRING HARBOR, N.Y. (Tues., March 3, 2009) Two new methods for analyzing the roles played by proteins in cells are featured in the March issue of Cold Spring Harbor Protocols ( www.cshprotocols.org/TOCs/toc3_09.dtl ). Thomas J. Wandless and colleagues from Stanford University ( http://w...

New manual presents robust, state-of-the-art proteomics methods for teaching and research

COLD SPRING HARBOR, N.Y. (Dec. 18, 2008) "Life happens at the level of proteins . . . They build, process, activate, and inactivate; they polymerize, repair, support, modify, degrade, fold, migrate, and transport; they shorten, signal, cleave, inhibit, digest, fluoresce, induce, excise, carry, ...

Deep biosphere research points to new methods for recovering petroleum

Miles below us, deep within Earth's crust, life is astir. Organisms there are not the large creatures typically envisioned when thinking of life. Instead, thriving there are microbes, the smallest and oldest form of life on Earth. Although the biological diversity of these deep biosphere microorga...

New lab manual focuses on essential methods for purifying and characterizing proteins

COLD SPRING HARBOR, N.Y. (Oct. 7, 2008) A new, user-friendly laboratory manual for protein purification and analysis has just been released by Cold Spring Harbor Laboratory Press. Designed for routine, day-to-day use in the laboratory, it includes essential step-wise protocols as well as backg...

HapMap browsing and DDDP methods for genetic analysis featured in CSH Protocols

COLD SPRING HARBOR, N.Y. (Tuesday, July 1, 2008) To aid in the study of genetic diseases, scientists with the International Haplotype Map Project have developed a haplotype map of the human genome, a tool that displays common patterns of genetic variation. While data from the project are ava...

Cold Spring Harbor Protocols features methods for analyzing genomes and plant cells

COLD SPRING HARBOR, N.Y. (Monday, June 2, 2008) With the sequencing of the human genome came the startling revelation that the number of copies of a genes and other DNA sequences can vary widely between individuals. This copy number variation (or CNV), contributes to our species' genetic diver...

Expanded histology methods book covers processing of animal, plant, and microbial tissues

COLD SPRING HARBOR, N.Y. For more than 25 years, the book Histological and Histochemical Methods has served as an established resource for researchers, students, and technologists in the biological and biomedical sciences who need to process normal or diseased tissues for microscopic analysis...

Cold Spring Harbor Protocols features methods to screen genomes and analyze evolution

COLD SPRING HARBOR, N.Y. (Tuesday, April 1, 2008) Identifying genes that are important in specific tissues or processes in the mouse used to be a monumental task. New technologies and strategies have simplified this search, making it effective for even the smallest laboratories. This months i...

Powerful yet reliable proteomics techniques are the focus of a new methods book

COLD SPRING HARBOR, N.Y. Conventional approaches to proteomics have recently been augmented with a new generation of technologies unfamiliar to many life science researchers. A new methods book, Proteomics: Methods Express , identifies the most powerful of these new technologies and presents ...

RNA-based methods for developmental studies are featured in Cold Spring Harbor Protocols

COLD SPRING HARBOR, N.Y. (Fri., Feb. 1, 2008) This months issue of Cold Spring Harbor Protocols ( www.cshprotocols.org/TOCs/toc2_08.dtl ) highlights two methods to understand developmental processes in plants and flies. Both methods involve work with RNA and are freely accessible on the Web ...

New book presents methods to poke and prod individual molecules

COLD SPRING HARBOR, N.Y. Single-molecule biologythe revolutionary field that deals with the study of individual macromoleculesis undergoing rapid growth. Tremendous technical advances have made it possible to probe molecules one by one, and to produce dynamic images as they twist, twirl, wobbl...

From brains to behavior: Cold Spring Harbor Protocols features methods for neuroscience research

COLD SPRING HARBOR, N.Y. (Mon., Oct. 1, 2007) Research in the field of neuroscience is constantly expanding to provide knowledge about biological mechanisms that underlie our ability to experience and interact with the world around us. To facilitate such research, two neuroscience methods are fea...

Contraception: progress brings hope for new methods for men

For decades, pundits have predicted new contraceptives for men within the next 5 to 10 years. Are we really getting any closer? Judging from work presented today at the second "Future of Male Contraception" conference, the answer may finally be yes. But will men actually use a new method if r...

Alternative methods proposed to detect pesticides and antibiotics in water and natural food

Water or food of natural origins (from plants or animals) that we consume on a daily basis can contain unwanted supplies for our organism, such as pesticides or antibiotics. A doctoral thesis carried out by Jorge Juan Soto Chinchilla, from the Department of Analytical Chemistry Department of Anal...

Researchers develop 'brain-reading' methods

It is widely known that the brain perceives information before it reaches a person's awareness. But until now, there was little way to determine what specific mental tasks were taking place prior to the point of conscious awareness. That has changed with the findings of scientists at Rutgers Un...

Infant formula adulteration with melamine underscores need for better detection methods

Rockville, Md., June 17, 2009 Following the recent adulteration of infant formula and other milk products with the industrial chemical melamine, the U. S. Pharmacopeial (USP) Convention is holding an international workshop this week to explore better ways to detect deliberately falsified protein ...

Cold Spring Harbor Protocols features stem cell differentiation, plant RNAi methods

COLD SPRING HARBOR, N.Y. (Mon., Feb. 2, 2009) -- By using OP9-DL1 cells as a support system, researchers can study the differentiation of embryonic stem cells into mature components of the immune system. This month's issue of Cold Spring Harbor Protocols ( www.cshprotocols.org/TOCs/toc2_09.d...

Cold Spring Harbor Protocols features organ and cell culture methods

COLD SPRING HARBOR, N.Y. (Mon., Nov. 3, 2008) Understanding the function of organs like the brain, kidney, and reproductive tissues requires experimental systems that allow for the study and manipulation of developing cells and tissues in the laboratory. This month's issue of Cold Spring Harb...

Radioactivity: Discover the lowest amounts with new methods

Detecting ever lower amounts of ionising radiation with ever better methods sci-entists have had this goal since the start of the nuclear age. In addition to natural radiation, mankind is exposed to a multitude of other sources of radiation which result from the military and technical use of radi...

Cold Spring Harbor Protocols highlights gene silencing, cancer cell biology methods

COLD SPRING HARBOR, N.Y. Combining the specificity of small interfering RNA (siRNA) silencing with the versatility of lentiviral vectors gives researchers a powerful tool for the investigation of gene function both in vivo and in vitro. This month's issue of Cold Spring Harbor Protocols ( w...

Application of Genomatix in silico methods reveals novel cancer associated genes

Genomatix Software GmbH, an in silico systems biology company with headquarter in Munich (Germany), released today that researcher in Dublin, Ireland and Boston, U.S.A. identified novel cancer associated genes, based on strategies and products developed and promoted by Genomatix. Experimental verif...

New methods offer insight into regulatory DNA

Through the Human Genome Project, the HapMap Project and other efforts, we are beginning to identify genes that are modified in some diseases. More difficult to measure and identify are the regulatory regions in DNA ?the 'managers' of genes ?that control gene activity and might be important in caus...

Researchers develop new testing methods for potential monkeypox or smallpox outbreak

Researchers at the Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University have developed new diagnostic methods to better detect future monkeypox or smallpox outbreaks. The research also sheds new light on the 2003 monkeypox outbreak in the Midwest -- monkeypox is close...

Scientists use manufacturing methods to reconstruct mastodon

Combining 13,000-year-old bones with 21st century auto manufacturing techniques, scientists and exhibit preparators at the University of Michigan Exhibit Museum of Natural history are reconstructing a male mastodon skeleton for an exhibit that opens to the public May 21. Meanwhile, museum visitor...

New methods of gene delivery using lasers

Leading laser scientists at the University of St Andrews have developed a new method of delivering genes to cells using laser light. The new technique, which is cheap and powerful, could have important implications for future studies in biomedicine and healthcare. Optical technology has huge pot...

Studies reveal methods viruses use to sidestep immune system

A series of studies by researchers at UT Southwestern Medical Center sheds light on the mechanisms used by viruses to thwart a host's immune defenses and may aid in the development of more effective drugs to fight hepatitis C and West Nile viruses, as well as the flu and the common cold. In a st...

Wastewater produces electricity and desalinates water

...s that allow water to pass but not salt -- or an electrodialysis process that uses electricity to draw salt ions out of water through a membrane. Both methods require large amounts of energy. "Water desalination can be accomplished without electrical energy input or high water pressure by using a source of...

'Green' energy from algae

...h and industry. Partly, large-scale facilities were constructed. "It is our objective to develop new economically efficient and sustainable extraction methods to obtain a maximum amount of cell constituents from the algae that can be used for energy production", says Mller. "The plant cells are exposed to a ...

Women often opt to surgically remove their breasts, ovaries to reduce cancer risk

...d and individualized for each patient." Likewise, Evans suggested that additional studies are needed to help evaluate the communication efforts and methods between doctors and/or counselors and women at risk for breast cancer. Questions to be raised should include how is the communication method occurring...

New DNA and RNA aptamers offer unique therapeutic advantages

...gies that have the highest likelihood of success. In the article entitled "Therapeutic Applications of DNA and RNA Aptamers," the authors describe the methods used to identify aptamers that specifically bind protein drug targets of interest, the types of modifications that have been made to aptamers to enhan...

Pinhead-size worms + robot = new antibiotics

...tibiotics. Their study appeared in ACS Chemical Biology , a monthly journal. Frederick Ausubel and colleagues note in the new study that existing methods for identifying germ-fighting drugs involve adding the potential drug to cultures of bacteria or cells and watching the results. These tests sometimes...

New stem cell research could reduce number of animal experiments

...d the mechanisms underlying the disease, but will also reduce the numbers of animals used in research. "There is a real need to develop alternative methods for studying these diseases that are more robust and better simulate how the disease develops in humans." The grant will fund a teaching replacemen...

Sustainable agriculture at the ESA Annual Meeting

... more ecosystem services in the long term." Reduced tilling improves soil microbe biodiversity The idea of using biological instead of chemical methods to create healthy croplands doesn't include just above-ground approaches. Soil bacteria can affect the growth and success of crop plants by fixing nit...

The way you eat may affect your risk for breast cancer

...of a growth factor (IGF-1) in relationship to these two calorie restriction methods chronic and intermittent and tumor development beginning in 10-week old f...ngs from clinical trials, Pollak suggested that lifestyle and pharmacologic methods to reduce IGF-1 and insulin deserve ongoing investigations. Cleary agreed, ...

Restoring a natural root signal helps to fight a major corn pest

...ern corn rootworm (Diabrotica virgifera virgifera) is the most damaging maize pest in the US and is responsible for enormous financial losses. Current methods to control the rootworm pest include insecticides, crop rotation and transgenic Bt maize lines that are not yet approved in Europe. After first invadi...

Global curbs on overfishing are beginning to work

... are seeing recovery in overall ecosystem structure, even if some species aren't fully recovered yet. "But we can't rest on our laurels. Management methods need to be tailored to particular fisheries and regions and also need to change through time as the system changes." Dr Fulton says surveys conduct...

Reducing risk of hospitalization in the elderly

... with a greater future risk of functional decline and disability. "Most methods of measuring muscle mass or density rely on complex imaging procedures, suc...onsuming and expensive," says Cawthon. "However, we found that much simpler methods such as measuring walking speed are much easier and cheaper to do, and ar...

New computer simulation helps explain folding in important cellular protein

...ms, such as the folding process of soluble proteins, polymers, DNA or protein complexes. Therefore, it is an excellent alternative to other simulation methods used traditionally in the field of protein-folding thermodynamics." In the current study, the team discovered something generally important about m...
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