Mello in Biological News

UMass Medical School's Craig Mello elected to American Academy of Arts and Sciences

WORCESTER, Mass.The American Academy of Arts & Sciences today announced that it has elected University of Massachusetts Medical Schools Craig C. Mello, PhD, to its membership, which includes some 200 Nobel laureates, more than 60 Pulitzer Prize winners and national and worldwide leaders drawn from...

RNA research strategy for Europe takes shape

...activity with the discovery in 1998 by US researchers Andrew Fire and Craig mello of a phenomenon called RNA interference, meaning that genes can be 'silenced' by RNA. This discovery, for which Fire and mello were awarded the Nobel Prize in 2006, revolutionised the way scientists thi...

MGH researcher Gary Ruvkun named a co-recipient of the Lasker Award

...n-4 and let-7 are released from their precursor hairpin RNA molecules by the enzyme Dicer, which is also critical to the RNA interference process that mello and Fire had discovered and for which they received the 2006 Nobel Prize. It now appears that the human genome contains between 500 and 1,000 micr...

Class of antibiotics can enhance gene-silencing tool

... the amount of RNA injected, which can trigger an anti-viral response, rather than from the genetic sequence of the RNA used. Andrew Fire and Craig mello received the 2006 Nobel Prize in Medicine for their discovery that short pieces of RNA, when introduced into cells, can silence a stretch of genetic c...

UMass Medical School researcher Victor Ambros receives Gairdner Award, Franklin Medal

..., received the Gairdner in 2005 for his work in the discovery of RNA interference with Andrew Z. Fire, PhD, of Stanford University School of Medicine. mello and Fire later received the 2006 Nobel Prize in Physiology or Medicine for the same work. Also this week, at the Franklin Institute in Philadelphi...

Mechanism for the in-vivo transport of siRNA

... Finally, in the late nineties the Nobel prizewinners Andrew Fire and Craig mello established the technique of RNA interference, in which double-stranded RNA...considerable problems arose in the attempt to transfer the strategy used by mello and Fire to vertebrates. In particular the administration of small RNAs, kn...

New approach to BSE successful in lab

... Bonn together with their colleagues at the Max Planck Institute in Martinsried. To do this they used an effect discovered by the US researchers Craig mello and Andrew Fire, for which they were awarded this year’s Nobel Prize for Medicine. Scrapie is a variant of the cattle disease BSE and the human equiva...

American scientist's research of life's first cells

...ve her award in Stockholm, Sweden, on Monday, 11 December, during an award ceremony. She will also meet with Nobel Prize winners Andrew Fire and Craig mello during her stay in Stockholm. Irene Chen received the grand prize for her essay, "The Emergence of Cells During the Origin of Life," which is being pu...

University of Iowa scientists explore function of 'junk DNA'

...ists discovered that some DNA produced small pieces of non-coding RNA that could turn off, or silence, genes. This discovery won Andrew Fire and Craig mello the 2006 Nobel Prize for medicine or physiology. Since their discovery, the field has exploded and small, non-coding RNAs have been shown to play an i...