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Medicines in Biological News

Comprehensive genetic study paves way for new blood-pressure medicines

Eight previously unknown genes that affect blood pressure were recently identified in a comprehensive international study comprising 34,433 Europeans. The findings of the study, in which Uppsala University researchers participated, are being presented today in the Web edition of Nature Genetics ....

Research exposes the risk to infants from the chemicals used in liquid medicines

A team of medical scientists from the University of Leicester has published research which looks into the harmful substances in liquid medicines that premature babies are being exposed to. Research published today (Jan 20) ahead of print in the Fetal & Neonatal Edition of Archives of Disease ...

Pregnant women with asthma can be more confident about some medicines

Budesonide sprays can be regarded as safe for pregnancy - other asthma drugs have not been as well studied though Women can usually keep using the same asthma drugs they were using before they got pregnant. Budesonide sprays are the best studied and can be regarded as safe. More trials of ot...

Producing medicines in plant seeds

Using plants to produce useful proteins could be an inexpensive alternative to current medicine production methods. Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) at Ghent University have succeeded in producing in plant seeds proteins that have a very strong resembl...

Protect patients from exploitation by alternative medicines industry

It is time to protect patients from “vile and cynical exploitation?by the alternative medicines industry, argues a cancer expert in this week’s BMJ. It is estimated that up to 80% of all patients with cancer take a complementary treatment or follow a dietary programme to help treat their cancer, ...

Transport System Smuggles Medicines Into Brain

Parrots, long a favorite pet animal, are attractive to owners because of their vibrant colors. But those colors may mean more to parrots than what meets the eye. For more than a century, biochemists have known that parrots use an unusual set of pigments to produce their rainbow of plumage colors...

121 breeding tigers estimated to be found in Nepal

...gal international trade in tiger parts and derivatives (skin, bones, meat in some cases although not reported in Nepal) and use in traditional Chinese medicines (TCM). Apart from these, sporadic cases of retaliatory killing from irate communities have been reported. Other important reasons of tiger population ...

Dietary supplements manufacturers gain new tool to help ensure quality products

...ications of standards for the identity, strength, purity and consistency of medicines and food ingredients, respectively. These specifications include items that...FDA if they fail to so conform). USP has been setting quality standards for medicines for nearly 200 years. ...

Research network wins approximately £5.7 million to target human and animal diseases in Africa

...nd interdisciplinary working groups investigating topics including: emerging and zoonotic diseases, linkages between agriculture and health, access to medicines in developing countries, and Distance Learning for Development (DL4D). ...

Axel Ullrich named winner of 2009 Dr. Paul Janssen Award for Biomedical Research

...d Ullrich. "Dr. Paul is a legend whose work had a tremendous impact on combating some of the world's most serious diseases. Four of the more than 80 medicines he developed are on the World Health Organization's list of essential medicines." "Johnson & Johnson is pleased the Selection Committee chose Dr. U...

DuoCort: New chronotherapy for adrenal insufficiency

...to optimize a drug's desired effects and minimize its undesired ones. Chronotherapy for the most part is not about new drug substances but about using medicines in new ways, better attuned to the bodys needs. Designing a drug so its release into the bloodstream has a particular release pattern or using pumps t...

American Chemical Society weekly presspac -- June 10, 2009

...4 FOR IMMEDIATE RELEASE Reengineering a food poisoning microbe to carry medicines and vaccines Molecular Pharmaceutics Scientists have used genetic e...ls and capsules to the discomfort and inconvenience of injections. But many medicines and vaccines cannot be given by mouth because they would be destroyed by st...

American Chemical Society's weekly PressPac -- May 27, 2009

...duled for the June 1 issue of ACS' Molecular Pharmaceutics , a bi-monthly journal. Finding ways to improve the stomach's uptake of poorly soluble medicines has been one of the major challenges facing pharmaceutical companies. Estimates suggest, for instance, that 40 percent of potential new drugs fall int...

International Serious Adverse Events Consortium announces initial study results in its global research collaboration to identify genetic markers related to drug induced liver injury

... involving researchers at the University of Liverpool and at Queen's Medical Centre, Nottingham. Patients respond differently to medicines, and all medicines can have adverse effects in some people. The SAEC's work is based on the hypothesis that many of these differences have a genetic basis. Its research...

Clinical trials for shingles drug take an important step forward

...rug said: "We believe this drug has the potential to be the most powerful inhibitor ever discovered to treat shingles. "Each year only 25 new medicines are approved for clinical use [worldwide or by the FDA]. Although FV-100 is early in its overall development plan, the chances of it becoming an appr...

University awarded £1.7M to develop nanotechnology for use in health care

...y techniques to develop new approaches for future drug development. Many medicines currently in use have poor solubility and have to be administered in large ...us the incurable disease that can lead to AIDS. There are more than 20 HIV medicines already on the market, which aim to prevent AIDS by ensuring that the disea...

WARF signs license agreement with Pfizer for human embryonic stem cells

...uman tissue. Our scientists will determine how new medicines may be able to improve the way stem cells regenera...lth care help people live longer, the need for new medicines to keep people healthy continues to grow. Pfizer r...tunity to discover and develop a new generation of medicines for major medical needs. Pfizer's initial research...

New hope for advances in treating malaria

...ds. Dr McConkey says: "Our chemicals are particularly exciting as they kill malaria parasites at low concentrations, something that is important for medicines as they are massively diluted on entering the bloodstream and, unlike many pharmaceutical products, we have a firm understanding of the molecular basi...

Our brains make their own marijuana: We're all pot heads deep inside

... that our brain has been making proteins that act directly on the marijuana receptors in our head. The next step is for scientists to come up with new medicines that eliminate the nasty side of pota better joint, so to speak." ...

American Chemical Society Weekly PressPac -- April 1, 2009

...m attacks myelin, a protective coating on many nerve fibers. This attack triggers a slowly worsening host of symptoms. Twenty years ago, few effective medicines were available for these patients. Many of the new drugs are pills rather than injectable medicines, making it easier for patients to take the med...

Ecologists question effects of climate change on infectious diseases

...es become warmer and regions near the equator become too hot. The newly suitable areas for diseases will tend to be in more affluent regions where medicines are in widespread use and can more readily combat the diseases, Lafferty says. He cites model estimations that the most dangerous kind of malaria will...

Codeine use and accident risk

...ic accident was 3 times as large. When the use of other potential impairing medicines was excluded, the risk of accident sank significantly. For sporadic codeine...sed to codeine who were included in the study had also been dispensed other medicines with abuse potential in the week prior to the accident. - One can concl...

Tobacco makes medicine

... Tobacco isn't famous for its health benefits. But now scientists have succeeded in using genetically modified tobacco plants to produce medicines for several autoimmune and inflammatory diseases, including diabetes. The research is published in the open access journal BMC Biotechnology . A l...

K-State biologist collaborating with researchers in Africa on grassland sustainability, biodiversity

...e dependence is more critical in Africa," Hartnett said. "Not only do the grasslands produce grain and meat, but they also produce building materials, medicines and other essential goods and services. That's what makes the grasslands such an important region to focus on." Hartnett said the research collabor...

MIT student develops new innovations to selectively kill cancer cells

...ineering systems of nanoparticles that collectively outsmart disease barriers has many potential applications in medicine, from improving regenerative medicines to ultra-sensitive diagnostics." Looking Forward Von Maltzahn's work has already made a significant impact scientifically and commercially, ...

Singapore research organisations team up to advance drug discovery using brain tumor stem cells

...ser to becoming a reality. Dr. Jonathon D. Sedgwick, LSCDD Managing Director and Chief Scientific Officer, said that "discovering new, breakthrough medicines through translational and clinical research requires intensive collaborations amongst partners. This research collaboration with clinicians and scient...

New target for medicine to combat Alzheimer's: VIB scientists confirm protein's key role

...as the disease progresses. Today, this disease cannot yet be cured. Current medicines for Alzheimer's patients sustain the memory functions for a short time, but...t of a new medicine against Alzheimer's disease. The majority of all of the medicines that are available in pharmacies − regardless of the disease that the...

Anadys Pharmaceuticals to Present at the Roth OC Growth Stock Conference

...rmaceutical company dedicated to improving patient care by developing novel medicines in the areas of hepatitis C and oncology. For the treatment of chronic hep...ces to Anadys' strategy, development programs, and ability to develop novel medicines in the areas of hepatitis C and oncology. Such forward-looking statements ...

GEN reports on strategies to overcome blood-brain barrier

... of approaches to preserve the ability of the BBB to block harmful and toxic substances from entering the brain and to permit the passage of effective medicines for the treatment of CNS diseases, according to the February 1 issue of GEN ( http://www.genengnews.com/articles/chitem.aspx?aid=2778 ). "The blo...

Acorda Therapeutics submits new drug application for Fampridine-SR in multiple sclerosis

... for patients, their families and their health care providers. There are no medicines currently indicated to improve walking ability in people with MS, and Fampr...e a centralized Marketing Authorization Application (MAA) with the European medicines Agency (EMEA). The Company plans to file the MAA when it has determined the...

Stress may hasten the growth of melanoma tumors

...plify the progression of their disease. But the same new research that infers this also suggests that the use of commonly prescribed blood pressure medicines might slow the development of those tumors and therefore improve these patients' quality of life. The study, the third by Ohio State University sci...

Study: Excessive use of antiviral drugs could aid deadly flu

...ges originated and where they are spreading. At the height of their popularity in China and Russia, adamantanes were added to over-the-counter cold medicines and were also given to animals in some agricultural settings. "We don't have hard data on how it was used or whether it was appropriately or inappr...

UT Southwestern researchers identify gene linked to inherited form of fatal lung disease

...rikes people in their 50s and older, causing severe scarring of the lungs. Death usually occurs within three years of diagnosis. "We don't have any medicines to treat this disease," said Dr. Christine Garcia, assistant professor in the Eugene McDermott Center for Human Growth and Development and of internal...

International public-private partnership offers new paradigm for medicinal chemistry

...link between the academic community and GSK in an emerging area of science should enhance knowledge and ultimately support our efforts to develop more medicines of benefit to patients." In keeping with SGC policy, the structure and function of each probe will promptly be made freely available. Traditionall...

American Chemical Society's Weekly PressPac -- Dec. 3, 2008

...., EASTERN TIME, Dec. 8, 2008 Updated standards to reduce metal contaminants in prescription drugs Chemical & Engineering News Prescription medicines in the United States could soon have lower levels of potentially harmful metals, as the organization that sets drug standards develops new limits for ...

Food can affect a cell in the same way hormones do

... important implications for the development of medicines. About half of all medicines are transmitted to cells via receptors, because receptors are located on th...also found in humans, then an unexpected new group of candidate targets for medicines becomes available − offering promising possibilities for the treatmen...

A spoonful of sugar?

...n about the barriers that prevent them from taking medicines prescribed for them. Funded with 328,247 from t... Professor Rachel Elliott, Lord Trent Professor of medicines and Health in The University of Nottingham's Schoo...her efforts have been made to improve adherence to medicines among children but studies have shown that simply ...

Superglue from the sea

...arket today." The synthetic glue also can carry drugs, so it could be used to deliver pain killers, growth factors, antibiotics, anti-inflammatory medicines or even stem cells to sites where bone fragments are glued, "simultaneously fixing the bone and delivering potent drugs or even genes to the spots whe...

Overuse of narcotics and barbiturates may make migraine worse

...e worse if these medications are overused. Treatment with these classes of medicines was associated with an increased risk of transformed migraine (TM) headache...levels of monthly headache days. "Proper treatment with the appropriate medicines can bring relief to most people with migraine," said Dr. Lipton. "Primary ...

Musculoskeletal center wins $2.2 million for drug safety

...2 million federal grant to study the risks and benefits of a newer class of medicines called biologics. These are genetically engineered therapies that target th...ry conditions diagnosed by rheumatologists and other specialists. "These medicines have revolutionized the way chronic inflammatory disease is treated, and th...
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