Labor

Scientists Replicate Hepatitis C Virus in Laboratory

For the first time, scientists have replicated hepatitis C virus (HCV) in the laboratory. The ability to replicate HCV in cell culture will allow researchers to better study the life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists at the National Institute of Diabetes...

Scientists collaborate to assess health of global environment

For the first time, a group of scientists has accomplished the daunting task of evaluating the status of all of the ecosystems on Earth, and the outlook is troubling. Commissioned by the United Nations in 2001, the Millennium Ecosystem Assessment program will issue its primary report on March 30 during press conferences in London, Washington, D.C., Tokyo, Beijing, New Delhi, Brasilia, Cai...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

Scientists at Affymetrix, Inc. (Nasdaq: AFFX) reported today in Science magazine online that they have completed a high-resolution scan of structure and function for nearly 30 percent of the human genome sequence. In collaboration with the National Cancer Institute, the research team used high-density GeneChip(R) microarrays to study every fifth base, on average, of 10 human chromosomes; they fou...

Innovative collaboration brings Arctic science into the classroom

An upcoming expedition to study the Yukon and Mackenzie Rivers is not simply a research project for R. Max Holmes, an associate scientist at The Woods Hole Research Center. It is also a means to integrate education and outreach into his work. In June and July, Dr. Holmes, an ecosystem scientist with broad interests in the responses and feedbacks of ecosystems to environmental and global ch...

Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory

Scientists in the UK have proved that human embryonic stem cells can develop in the laboratory into the early forms of cells that eventually become eggs or sperm. Their work opens up the possibility that eggs and sperm could be grown from stem cells and used for assisted reproduction, therapeutic cloning and the creation of more stem cells for further research and for the improved treatments for...

Novel laboratory technique nudges genes into activity

A new technique that employs RNA, a tiny chemical cousin of DNA, to turn on genes could lead to therapeutics for conditions in which nudging a gene awake would help alleviate disease, researchers at UT Southwestern Medical Center say. The gene-activating method, which is being developed by UT Southwestern scientists, also is providing researchers with a novel research tool to investigate...

Laboratory professionals in Africa receive training under AIDS Relief Plan

The American Society for Clinical Pathology (ASCP) announced that the Society will receive approximately $1.5 million in federal funds to continue to provide laboratory training and quality improvement programs in African countries severely affected by AIDS. The training programs are for medical laboratory professionals in Africa and will continue in 2006 through the President's Emergency Plan f...

UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina

In the immediate wake of Hurricane Katrina, scientists and research centers from across the country came together to generate information on the contaminated floodwaters and offer it to hazardous materials experts and public health officials. In a matter of hours, the University of North Carolina at Chapel Hill's Marine Sciences Program and Renaissance Computing Institute (RENCI), together...

Solexa and collaborating scientists illuminate the small RNA component of the transcriptome

Solexa, Inc. (Nasdaq: SLXA) today announced that its researchers in collaboration with the Delaware Biotechnology Institute and the University of Delaware reported the most comprehensive analysis to date of the small RNA component of the transcriptome. The research, "Elucidation of the Small RNA Component of the Transcriptome," was published in the September 2, 2005 issue of the peer-reviewed jou...

Melanoma vaccine strategy shows promise in laboratory experiments

A novel approach to creating a vaccine to treat melanoma has demonstrated promising effectiveness in a new laboratory study led by researchers at The Wistar Institute. About a third of melanoma patients might benefit from such a vaccine. The study appears in the current issue of Cancer Research. In the study, the scientists used a small protein called a peptide found in approximately 70 pe...

Mayo Clinic collaboration discovers protein amplifies DNA injury signals

A Mayo Clinic-led research collaboration has discovered that the protein MDC1 amplifies weak DNA injury signals so genetic repair can begin. Once amplified, even low-level damage signals become strong enough to activate the cell's natural repair processes while the injury is most tractable to repair. How this "distress call" was communicated wasn't clear until this finding, which appears...

Component in soy products causes reproductive problems in laboratory mice

Genistein, a major component of soy, was found to disrupt the development of the ovaries in newborn female mice that were given the product. This study adds to a growing body of literature demonstrating the potentially adverse consequences of genistein on the reproductive system. "Although we are not entirely certain about how these animal studies on genistein translate to the human popula...

New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice

Results from a new study in laboratory mice show that nighttime exposure to artificial light stimulated the growth of human breast tumors by suppressing the levels of a key hormone called melatonin. The study also showed that extended periods of nighttime darkness greatly slowed the growth of these tumors. The study results might explain why female night shift workers have a higher rate of...

Sperm created in the laboratory from embryonic stem cells produce viable progeny

Scientists have demonstrated for the first time that embryonic stem (ES) cells cultured in the laboratory can produce sperm with the capacity to produce viable offspring. The research, published in the July issue of Developmental Cell, opens many exciting avenues for future studies, including investigation of mechanisms involved in sperm production and development of new treatment strategies for...

Mayo Clinic collaboration mining of ancient herbal text leads to potential new anti-bacterial drug

A unique Mayo Clinic collaboration has revived the healing wisdom of Pacific Island cultures by testing a therapeutic plant extract described in a 17th century Dutch herbal text for its anti-bacterial properties. Early results show that extracts from the Atun tree effectively control bacteria that can cause diarrhea, as claimed by naturalist Georg Eberhard Rumpf, circa 1650. He documented his tra...

Living laboratory found on shoreline statues

A team from the University of Liverpool's School of Biological Sciences have found that the 100 life-size statues which make up Antony Gormley's 'Another Place' art installation on Crosby Beach have become a haven for a settlement of a particular breed of barnacle - Elminius modestus. Although the barnacles have been present on North West shorelines since the 1950s, they originate from hal...

Technology for monitoring fetal oxygen during labor offers no apparent benefit

A new technology for measuring blood oxygen levels of a baby during labor--expected to provide information useful for preventing birth complications--offers no apparent benefit, report researchers in a National Institutes of Health research network. The technology, known as fetal oxygen saturation monitoring, was designed for use along with electronic fetal monitoring, which tracks the fet...

Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu

Researchers at the University of California, San Diego and the University of Hawaii will use bioinformatics, grid computing and networking infrastructure, as well as collaborative ties to Asian institutions to learn more about avian flu, in hopes of helping to head off a much-feared pandemic in the region of the world where the disease has already cost human lives. "We will use modern h...

New collaborative research reveals chimpanzees can sustain multiple-tradition cultures

The study, available in today’s online edition of Current Biology, confirms captive chimpanzees have the capacity to sustain...